W Borkowsky

Summary

Affiliation: New York University
Country: USA

Publications

  1. ncbi request reprint Correlation between HIV-Specific CD8 cell production of interferon- gamma and plasma levels of HIV RNA in perinatally infected pediatric populations
    William Borkowsky
    The Saul Krugman Division of Infectious Diseases, Division of Pediatrics, New York University School of Medicine, New York, New York 10016, USA
    J Infect Dis 190:722-6. 2004
  2. doi request reprint Planned multiple exposures to autologous virus in HIV type 1-infected pediatric populations increases HIV-specific immunity and reduces HIV viremia
    William Borkowsky
    NYU School of Medicine, New York, New York 10016, USA
    AIDS Res Hum Retroviruses 24:401-11. 2008
  3. pmc Structured treatment interruptions (STIs) in HIV-1 infected pediatric populations increases interferon gamma production and reduces viremia
    William Borkowsky
    NYU School of Medicine, New York, NY, USA
    Vaccine 26:3086-9. 2008
  4. pmc Distribution and evolution of T-cell receptor Vbeta repertoire on peripheral blood lymphocytes of newborn infants of human immunodeficiency virus (HIV)-infected mothers: differential display on CD4 and CD8 T cells and effect of HIV infection
    William Borkowsky
    Department of Pediatrics, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Clin Vaccine Immunol 14:1215-22. 2007
  5. doi request reprint Insulin-like growth factor-1 and lean body mass in HIV-infected children
    Caroline J Chantry
    Department of Pediatrics, University of California Davis Medical Center, 2516 Stockton Boulevard, Sacramento, CA 95817, USA
    J Acquir Immune Defic Syndr 48:437-43. 2008
  6. ncbi request reprint Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team
    S A Nachman
    Department of Pediatrics, State University of New York at Stony Brook, 11794 8111, USA
    JAMA 283:492-8. 2000
  7. ncbi request reprint Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women
    C K Cunningham
    Department of Pediatrics, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Clin Infect Dis 32:801-7. 2001
  8. ncbi request reprint Lymphoproliferative responses to recombinant HIV-1 envelope antigens in neonates and infants receiving gp120 vaccines. AIDS Clinical Trial Group 230 Collaborators
    W Borkowsky
    The Saul Krugman Division of Infectious Diseases and Immunology, New York University Medical School, New York, NY 10016, USA
    J Infect Dis 181:890-6. 2000
  9. ncbi request reprint Changes in frequency of HIV-1-specific cytotoxic T cell precursors and circulating effectors after combination antiretroviral therapy in children
    H M Spiegel
    Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA
    J Infect Dis 180:359-68. 1999
  10. pmc Impact of medications prescribed for treatment of attention-deficit hyperactivity disorder on physical growth in children and adolescents with HIV
    Patricia A Sirois
    Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA 70112, USA
    J Dev Behav Pediatr 30:403-12. 2009

Research Grants

  1. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 1999
  2. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 2000
  3. ABI PRISM 7700 SEQUENCE DETECTION SYSTEM
    William Borkowsky; Fiscal Year: 2001
  4. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 2001
  5. PEDIATRIC AIDS CLINICAL TRIALS UNIT
    William Borkowsky; Fiscal Year: 2002
  6. Core--HIV Virology and Sequencing
    William Borkowsky; Fiscal Year: 2008

Detail Information

Publications49

  1. ncbi request reprint Correlation between HIV-Specific CD8 cell production of interferon- gamma and plasma levels of HIV RNA in perinatally infected pediatric populations
    William Borkowsky
    The Saul Krugman Division of Infectious Diseases, Division of Pediatrics, New York University School of Medicine, New York, New York 10016, USA
    J Infect Dis 190:722-6. 2004
    ..Attempts to establish the same correlation in small numbers of children have also been made, with similar controversy resulting...
  2. doi request reprint Planned multiple exposures to autologous virus in HIV type 1-infected pediatric populations increases HIV-specific immunity and reduces HIV viremia
    William Borkowsky
    NYU School of Medicine, New York, New York 10016, USA
    AIDS Res Hum Retroviruses 24:401-11. 2008
    ..Other studies may have failed due to an insufficient number of exposures to HIV; most of the studies had fewer than six drug interruptions...
  3. pmc Structured treatment interruptions (STIs) in HIV-1 infected pediatric populations increases interferon gamma production and reduces viremia
    William Borkowsky
    NYU School of Medicine, New York, NY, USA
    Vaccine 26:3086-9. 2008
    ..This allowed us to conclude that exposure to autologous virus increased HIV-specific immune responses and decreased HIV RNA were seen in those who have had >13 interruptions, with STI intervals that exceeded 27 days...
  4. pmc Distribution and evolution of T-cell receptor Vbeta repertoire on peripheral blood lymphocytes of newborn infants of human immunodeficiency virus (HIV)-infected mothers: differential display on CD4 and CD8 T cells and effect of HIV infection
    William Borkowsky
    Department of Pediatrics, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Clin Vaccine Immunol 14:1215-22. 2007
    ..In conclusion, newborns demonstrate different distributions of TCR Vbeta types on CD4 and CD8 cells. HIV infection produces no change in neonatal TCR and little change over the course of 2 years compared to that seen in the uninfected...
  5. doi request reprint Insulin-like growth factor-1 and lean body mass in HIV-infected children
    Caroline J Chantry
    Department of Pediatrics, University of California Davis Medical Center, 2516 Stockton Boulevard, Sacramento, CA 95817, USA
    J Acquir Immune Defic Syndr 48:437-43. 2008
    ....
  6. ncbi request reprint Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team
    S A Nachman
    Department of Pediatrics, State University of New York at Stony Brook, 11794 8111, USA
    JAMA 283:492-8. 2000
    ..Although protease inhibitors are used routinely in adults with human immunodeficiency virus (HIV) infection, the role of these drugs in the treatment of clinically stable HIV-infected children is not clear...
  7. ncbi request reprint Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women
    C K Cunningham
    Department of Pediatrics, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Clin Infect Dis 32:801-7. 2001
    ..Thus, both vaccines were safe and well tolerated in neonates, and there was no evidence of accelerated immunologic decline in HIV-infected infants...
  8. ncbi request reprint Lymphoproliferative responses to recombinant HIV-1 envelope antigens in neonates and infants receiving gp120 vaccines. AIDS Clinical Trial Group 230 Collaborators
    W Borkowsky
    The Saul Krugman Division of Infectious Diseases and Immunology, New York University Medical School, New York, NY 10016, USA
    J Infect Dis 181:890-6. 2000
    ..Responses to heterologous envelope antigens were also detected. Immune responses to vaccination are achievable at an age when some infection (perinatal or breast milk exposure related) may be prevented...
  9. ncbi request reprint Changes in frequency of HIV-1-specific cytotoxic T cell precursors and circulating effectors after combination antiretroviral therapy in children
    H M Spiegel
    Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA
    J Infect Dis 180:359-68. 1999
    ..In children with complete viral suppression, the frequency of HIV-1-specific CTL responses decreased, suggesting that viral replication is required to maintain CTL responses in the systemic circulation...
  10. pmc Impact of medications prescribed for treatment of attention-deficit hyperactivity disorder on physical growth in children and adolescents with HIV
    Patricia A Sirois
    Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA 70112, USA
    J Dev Behav Pediatr 30:403-12. 2009
    ..To examine the relationships between physical growth and medications prescribed for symptoms of attention-deficit hyperactivity disorder in children with HIV...
  11. pmc Predictors of growth and body composition in HIV-infected children beginning or changing antiretroviral therapy
    C J Chantry
    Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA 95817, USA
    HIV Med 11:573-83. 2010
    ..The aim of the study was to describe growth and body composition changes in HIV-positive children after they had initiated or changed antiretroviral therapy (ART) and to correlate these with viral, immune and treatment parameters...
  12. ncbi request reprint Immunologic response to combination nucleoside analogue plus protease inhibitor therapy in stable antiretroviral therapy-experienced human immunodeficiency virus-infected children
    W Borkowsky
    Division of Infectious Diseases, New York University School of Medicine, New York, NY 10016, USA
    J Infect Dis 182:96-103. 2000
    ..02) by week 48 in this clinically stable population. Changes in lymphoproliferative responses to HIV antigens and recall antigens did not increase over time and between groups...
  13. ncbi request reprint The impact of early initiation of highly active antiretroviral therapy on the human immunodeficiency virus type 1-specific CD8 T cell response in children
    H M Spiegel
    Aaron Diamond AIDS Research Center, Rockefeller University, New York, NY 10016, USA
    J Infect Dis 182:88-95. 2000
    ..Thus, the reduced magnitude and breadth of the HIV-1-specific CD8 T cell response in early HAART-treated children is due to their younger age...
  14. ncbi request reprint Prevalence of the T215Y mutation in human immunodeficiency virus type 1-infected pregnant women in a New York cohort, 1995--1999
    Y Sitnitskaya
    Division of Pediatric Infectious Diseases, New York University School of Medicine, New York, NY, USA
    Clin Infect Dis 33:e3-7. 2001
    ..All mutations were noted in women with zidovudine experience, which suggests that monotherapy may not be adequate prophylaxis for vertical transmission of HIV-1 infection in the current era...
  15. ncbi request reprint Early changes in quasispecies repertoire in HIV-infected infants: correlation with disease progression
    S M Essajee
    Department of Pediatric Infectious Diseases, New York University Medical Center, New York City, New York 10016, USA
    AIDS Res Hum Retroviruses 16:1949-57. 2000
    ..These results show that in HIV-infected children, multiple variants may initiate infection and early quasispecies diversification is associated with a favorable clinical outcome...
  16. pmc Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection
    Aimee El Hed
    Departments of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    J Infect Dis 201:843-54. 2010
    ..Identification of the Th17 T cell subset as important mediators of host defense and pathology prompted us to determine their susceptibility to human immunodeficiency virus (HIV) infection...
  17. pmc Metabolic abnormalities and viral replication are associated with biomarkers of vascular dysfunction in HIV-infected children
    T I Miller
    Department of Pediatrics, Division of Pediatric Clinical Research, Miller School of Medicine at the University of Miami, Miami, FL, USA
    HIV Med 13:264-75. 2012
    ....
  18. ncbi request reprint Human immunodeficiency virus type 1 antigenemia in children
    W Borkowsky
    Department of Pediatrics, New York University Medical Center, NY 10016
    J Pediatr 114:940-5. 1989
    ..Plasma core antigen was less frequent in children without symptoms and was not detected in 10 infected children when they were tested at birth...
  19. pmc Dynamics of human immunodeficiency virus type 1 replication in vertically infected infants
    K Luzuriaga
    Department of Pediatrics, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Boston, Massachusetts, USA
    J Virol 73:362-7. 1999
    ..These data confirm the central role of HIV-1 replication in the pathogenesis of vertical HIV-1 infection and reinforce the importance of early, potent combination therapies for the long-term control of HIV-1 replication...
  20. ncbi request reprint Immunoreconstitution in children receiving highly active antiretroviral therapy depends on the CD4 cell percentage at baseline
    Divna Nikolic-Djokic
    New York University Medical Center, New York, NY 10016, USA
    J Infect Dis 185:290-8. 2002
    ..The results support the option of delaying HAART in early asymptomatic HIV-1 disease in children and the use of other markers of disease progression, in addition to virus load...
  21. doi request reprint Assessment of adherence to antiretroviral therapy in perinatally HIV-infected children and youth using self-report measures and pill count
    John J Farley
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Dev Behav Pediatr 29:377-84. 2008
    ..The purpose of this study was to compare these different methods with one another and with viral load...
  22. doi request reprint Erythema induratum of Bazin in a child: evidence for a cell-mediated hyper-response to Mycobacterium tuberculosis
    Jennifer Lighter
    From the Department of Pediatrics, New York University School of Medicine, New York, NY, USA
    Pediatr Infect Dis J 28:326-8. 2009
    ..5 cm of induration and an interferon-gamma releasing assay was also markedly positive. A diagnosis of erythema induratum of Bazin was confirmed on skin biopsy. The patient was successfully treated with multi-drug antituberculosis therapy...
  23. pmc HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites
    Charlotte V Hobbs
    NYU School of Medicine, Dept of Pediatrics, Div of Infectious Disease, 550 First Ave, 8W New Bellevue, NY, NY 10010, USA
    J Infect Dis 199:134-41. 2009
    ..We found that lopinavir/ritonavir had a dose-dependent effect on liver-stage parasite development. Given that sub-Saharan Africa is where the HIV/AIDS pandemic intersects with malaria, these results merit analysis in clinical settings...
  24. doi request reprint Hyper interleukin-10 in an HIV-positive child with t-cell lymphoma and candidal sepsis
    Jennifer Lighter
    Saul Krugman Division of Pediatric Infectious Diseases and Immunology, New York University School of Medicine, New York, New York
    J Int Assoc Physicians AIDS Care (Chic) 7:228-31. 2008
    ..Significantly elevated levels of Interleukin-10 (IL-10) were found in the patient's serum, which may have played a role in acute demise...
  25. ncbi request reprint Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages
    Yoshihiko Hoshino
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    J Immunol 172:6251-8. 2004
    ..These changes explain in part why TB accelerates the course of AIDS. CXCR4 inhibitors are a rational therapeutic approach in HIV/TB coinfection...
  26. pmc Impaired immunity to recall antigens and neoantigens in severely immunocompromised children and adolescents during the first year of effective highly active antiretroviral therapy
    Mona Rigaud
    New York University School of Medicine, New York, NY, USA
    J Infect Dis 198:1123-30. 2008
    ....
  27. pmc Recombinant glycoprotein vaccines for human immunodeficiency virus-infected children and their effects on viral quasispecies
    Shaffiq M Essajee
    Department of Pediatrics, Division of Infectious Diseases, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Clin Diagn Lab Immunol 9:79-82. 2002
    ..These results suggest that the immune response elicited by RGP vaccines does not exert a significant selection pressure on the viral quasispecies and therefore may not be helpful in changing the course of the disease...
  28. doi request reprint Implementation of HIV testing at 2 New York City bathhouses: from pilot to clinical service
    Demetre Daskalakis
    Division of Infectious Diseases and Immunology, New York University Langone Medical Center, New York, New York 10016, USA
    Clin Infect Dis 48:1609-16. 2009
    ..Several cities in the United States have developed programs that offer HIV testing in these venues. Similar programs have not existed before in New York City...
  29. ncbi request reprint Human immunodeficiency virus type 1 (HIV-1) gp120-specific antibodies in neonates receiving an HIV-1 recombinant gp120 vaccine
    E J McFarland
    Department of Pediatrics, University of Colorado Health Science Center, Denver, CO 80262, USA
    J Infect Dis 184:1331-5. 2001
    ..These results provide support for further studies of vaccine strategies to prevent mother-to-infant HIV-1 transmission...
  30. ncbi request reprint Natural history of HIV infected pediatric long-term or slow progressor population after the first decade of life
    Juliana A Ofori-Mante
    Department of Pediatrics, Division of Infectious Diseases, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Pediatr Infect Dis J 26:217-20. 2007
    ..There is very limited information on this group of children beyond the first decade of life. A group of HIV-infected long-term nonprogressor/slow progressor children was studied...
  31. pmc CCR5 expression and duration of high risk sexual activity among HIV-seronegative men who have sex with men
    Susan M Thomas
    Department of Environmental Medicine, New York University School of Medicine, NY 10016 3240, USA
    AIDS 20:1879-83. 2006
    ....
  32. pmc Toxicities associated with dual nucleoside reverse-transcriptase inhibitor regimens in HIV-infected children
    Russell B Van Dyke
    Department of Pediatrics, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    J Infect Dis 198:1599-608. 2008
    ..Human immunodeficiency virus (HIV) therapy includes a backbone of nucleoside reverse-transcriptase inhibitors (NRTIs). Toxicities associated with NRTIs are not fully defined in children...
  33. ncbi request reprint Group-specific antibody levels surrounding invasive pneumococcal illness in children infected with human immunodeficiency virus
    J C King
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Infect Dis 181:1817-21. 2000
    ..Heterologous, noninfecting group seroresponses were detected frequently (72%) in the paired serum samples from these 4 homologous group seroresponders...
  34. pmc Immunological memory after exposure to variola virus, monkeypox virus, and vaccinia virus
    Sumathi Sivapalasingam
    Division of Infectious Disease, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    J Infect Dis 195:1151-9. 2007
    ..Survivors of variola virus infection demonstrated VV-specific CD4 memory cell responses and neutralizing antibodies >40 years after infection...
  35. pmc Safety and immunogenicity of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine in HIV-infected children 7 to 12 years old
    Myron J Levin
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:197-204. 2010
    ..Quadrivalent human papillomavirus vaccine (QHPV) is > 95% effective in preventing infection with vaccine-type human papillomavirus. The safety and immunogenicity of QHPV are unknown in HIV-infected children...
  36. ncbi request reprint Perinatal transmission and viral evolution of hepatitis C virus quasispecies in infants coinfected with HIV
    Henry Pollack
    Department of Pediatrics, The Saul Krugman Division of Infectious Diseases and Immunology, New York University School of Medicine, NY 10016, USA
    J Acquir Immune Defic Syndr 36:890-9. 2004
    ..Sequences of the hypervariable region in the N terminus of the E2/NS1 region (HVR-1) of the children and their mothers were compared. HCV quasispecies changes in the infants were tracked over several years...
  37. pmc Lipid and glucose alterations in HIV-infected children beginning or changing antiretroviral therapy
    Caroline J Chantry
    Department of Pediatrics, University of California Davis Medical Center, Sacramento, California 95817, USA
    Pediatrics 122:e129-38. 2008
    ....
  38. pmc Incidence of noninfectious conditions in perinatally HIV-infected children and adolescents in the HAART era
    Sharon A Nachman
    Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794 8111, USA
    Arch Pediatr Adolesc Med 163:164-71. 2009
    ....
  39. pmc A phase I-II study of live attenuated varicella-zoster virus vaccine to boost immunity in human immunodeficiency virus-infected children with previous varicella
    Anne A Gershon
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Pediatr Infect Dis J 28:653-5. 2009
    ..There were no serious adverse events. Two years after vaccination 82% of subjects remained VZV-antibody positive and 60% had VZV-specific cell-mediated immunity. No child developed herpes zoster...
  40. ncbi request reprint Cutaneous anthrax associated with microangiopathic hemolytic anemia and coagulopathy in a 7-month-old infant
    Abigail Freedman
    Department of Pediatrics, New York University Medical Center, 550 First Ave, New York, NY 10016, USA
    JAMA 287:869-74. 2002
    ..The systemic manifestations of the disease persisted for nearly a month despite corticosteroid therapy, but resolved...
  41. pmc Anti-influenza serum and mucosal antibody responses after administration of live attenuated or inactivated influenza vaccines to HIV-infected children
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:189-96. 2010
    ..Live-attenuated influenza vaccine (LAIV) prevents more cases of influenza in immune-competent children than the trivalent inactivated vaccine (TIV). We compared the antibody responses to LAIV or TIV in HIV-infected children...
  42. ncbi request reprint Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age
    Ellen Gould Chadwick
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Pediatr Infect Dis J 24:793-800. 2005
    ..Few data are available regarding clinical outcomes or dosing requirements for the protease inhibitor ritonavir in human immunodeficiency virus (HIV)-infected children younger than under 24 months of age...
  43. ncbi request reprint Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in human immunodeficiency virus-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    University of Colorado School of Medicine, Pediatric Infectious Disease, The Children s Hospital, Denver, CO 80218, USA
    Pediatr Infect Dis J 25:920-9. 2006
    ....
  44. ncbi request reprint Pertussis booster vaccination in HIV-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    School of Medicine, University of Colorado and Children s Hospital, Denver, Colorado, USA
    Pediatrics 120:e1190-202. 2007
    ..Our goal was to evaluate the immunogenicity and safety of pertussis booster vaccination in children infected with HIV on highly active antiretroviral therapy (HAART)...
  45. pmc Association of hypercholesterolemia incidence with antiretroviral treatment, including protease inhibitors, among perinatally HIV-infected children
    Katherine Tassiopoulos
    Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 47:607-14. 2008
    ..Antiretroviral therapy has been associated with hypercholesterolemia in HIV-infected children. Few longitudinal studies have been conducted to examine this association, however...
  46. ncbi request reprint Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents
    Chang Heok Soh
    Department of Biostatistics, Harvard School of Public Health, MA, Boston 02115, USA
    Lancet 362:2045-51. 2003
    ..Better understanding might help to resolve questions on when to initiate treatment...
  47. pmc Association of site-specific and participant-specific factors with retention of children in a long-term pediatric HIV cohort study
    Paige L Williams
    Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115 6017, USA
    Am J Epidemiol 167:1375-86. 2008
    ..Although participant characteristics are difficult to modify, the authors identified several potentially modifiable site practices that could be targeted to improve retention...
  48. pmc Long-term effects of highly active antiretroviral therapy on CD4+ cell evolution among children and adolescents infected with HIV: 5 years and counting
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:1751-60. 2008
    ....
  49. pmc Pharmacokinetics of high-dose lopinavir-ritonavir with and without saquinavir or nonnucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected pediatric and adolescent patients previously treated with protease inhibitors
    Brian L Robbins
    St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Antimicrob Agents Chemother 52:3276-83. 2008
    ....

Research Grants9

  1. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 1999
    ..The influence of both maternal and child alleles on transmission will be assessed. The correlation of immune responses measured in AIM 3 and the clinical outcome of HCV infection with HLA alleles in the child will be studied. ..
  2. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 2000
    ..The influence of both maternal and child alleles on transmission will be assessed. The correlation of immune responses measured in AIM 3 and the clinical outcome of HCV infection with HLA alleles in the child will be studied. ..
  3. ABI PRISM 7700 SEQUENCE DETECTION SYSTEM
    William Borkowsky; Fiscal Year: 2001
    ..The principal investigator will be responsible for helping design primers and probes for the instrument as well as insure that the assay and those who manage it undergo appropriate quality control procedures. ..
  4. BIOLOGY OF PEDIATRIC HEPATITIS C INFECTION
    William Borkowsky; Fiscal Year: 2001
    ..The influence of both maternal and child alleles on transmission will be assessed. The correlation of immune responses measured in AIM 3 and the clinical outcome of HCV infection with HLA alleles in the child will be studied. ..
  5. PEDIATRIC AIDS CLINICAL TRIALS UNIT
    William Borkowsky; Fiscal Year: 2002
    ..This effort will also be helped by established links to previously funded community resources, our community advisory board, and by our own local General Clinical Research Center. ..
  6. Core--HIV Virology and Sequencing
    William Borkowsky; Fiscal Year: 2008
    ..abstract_text> ..