Martin J Blaser

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta)
    Sabine Kienesberger
    Department of Medicine, NYU Langone Medical Center, New York, NY, USA
    Gut Pathog 4:9. 2012
  2. pmc Antibiotic exposure and the development of coeliac disease: a nationwide case-control study
    Karl Mårild
    Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
    BMC Gastroenterol 13:109. 2013
  3. pmc Distinct cutaneous bacterial assemblages in a sampling of South American Amerindians and US residents
    Martin J Blaser
    Department of Medicine, New York University Langone Medical Center, New York, NY 10016, USA
    ISME J 7:85-95. 2013
  4. pmc Equilibria of humans and our indigenous microbiota affecting asthma
    Martin J Blaser
    Department of Medicine, New York University Langone Medical Center, 550 First Avenue, OBV A606, New York, NY 10016, USA
    Proc Am Thorac Soc 9:69-71. 2012
  5. ncbi request reprint Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation
    Michael H Pillinger
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Biol Chem 282:18722-31. 2007
  6. pmc Substantial alterations of the cutaneous bacterial biota in psoriatic lesions
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 3:e2719. 2008
  7. pmc Repeat-associated plasticity in the Helicobacter pylori RD gene family
    Joshua R Shak
    Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Bacteriol 191:6900-10. 2009
  8. ncbi request reprint Natural variation in populations of persistently colonizing bacteria affect human host cell phenotype
    Rahul A Aras
    Departments of Medicine and Microbiology, New York University School of Medicine, New York, New York, USA
    J Infect Dis 188:486-96. 2003
  9. pmc Serological assays for identification of human gastric colonization by Helicobacter pylori strains expressing VacA m1 or m2
    Chandrabali Ghose
    Department of Microbiology, New York University School of Medicine, New York, New York, USA
    Clin Vaccine Immunol 14:442-50. 2007
  10. pmc Leptin and ghrelin in relation to Helicobacter pylori status in adult males
    Jatin Roper
    New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Endocrinol Metab 93:2350-7. 2008

Collaborators

Detail Information

Publications70

  1. pmc Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta)
    Sabine Kienesberger
    Department of Medicine, NYU Langone Medical Center, New York, NY, USA
    Gut Pathog 4:9. 2012
    ..abstract:..
  2. pmc Antibiotic exposure and the development of coeliac disease: a nationwide case-control study
    Karl Mårild
    Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
    BMC Gastroenterol 13:109. 2013
    ..Although antibiotics are common environmental factors with a profound impact on intestinal microbiota, data on antibiotic use as a risk factor for subsequent CD development are scarce...
  3. pmc Distinct cutaneous bacterial assemblages in a sampling of South American Amerindians and US residents
    Martin J Blaser
    Department of Medicine, New York University Langone Medical Center, New York, NY 10016, USA
    ISME J 7:85-95. 2013
    ..The results provide evidence that ethnicity, lifestyle and/or geography are associated with the structure of human cutaneous bacterial communities...
  4. pmc Equilibria of humans and our indigenous microbiota affecting asthma
    Martin J Blaser
    Department of Medicine, New York University Langone Medical Center, 550 First Avenue, OBV A606, New York, NY 10016, USA
    Proc Am Thorac Soc 9:69-71. 2012
    ..pylori protects against childhood-onset asthma, probably through the gastric recruitment of regulatory T cells. The phenomenon of disappearing ancient microbiota may be a general paradigm driving the diseases of modernity...
  5. ncbi request reprint Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation
    Michael H Pillinger
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Biol Chem 282:18722-31. 2007
    ..These data indicate H. pylori effects on host epithelial MMP-1 expression via ERK, with p38 playing a potential regulatory role...
  6. pmc Substantial alterations of the cutaneous bacterial biota in psoriatic lesions
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 3:e2719. 2008
    ..001), whereas normal skin from the psoriatic patients showed intermediate levels (12.3+/-21.6%). We conclude that psoriasis is associated with substantial alteration in the composition and representation of the cutaneous bacterial biota...
  7. pmc Repeat-associated plasticity in the Helicobacter pylori RD gene family
    Joshua R Shak
    Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Bacteriol 191:6900-10. 2009
    ..This novel family of hypervariable genes with conserved, repetitive, and allelic domains may represent an important locus for understanding H. pylori persistence in its natural host...
  8. ncbi request reprint Natural variation in populations of persistently colonizing bacteria affect human host cell phenotype
    Rahul A Aras
    Departments of Medicine and Microbiology, New York University School of Medicine, New York, New York, USA
    J Infect Dis 188:486-96. 2003
    ..These findings indicate that within an individual host, intragenomic recombination between H. pylori repetitive DNA produces strain variants differing in their signals to host cells...
  9. pmc Serological assays for identification of human gastric colonization by Helicobacter pylori strains expressing VacA m1 or m2
    Chandrabali Ghose
    Department of Microbiology, New York University School of Medicine, New York, New York, USA
    Clin Vaccine Immunol 14:442-50. 2007
    ..In an Asian-American population, serologic responses to VacA m region-specific antigens were not able to predict the risk of development of gastric cancer...
  10. pmc Leptin and ghrelin in relation to Helicobacter pylori status in adult males
    Jatin Roper
    New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Endocrinol Metab 93:2350-7. 2008
    ..Leptin and ghrelin, hormones involved in human energy homeostasis, are both produced in the stomach...
  11. pmc Early-life family structure and microbially induced cancer risk
    Martin J Blaser
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS Med 4:e7. 2007
    ..In this study, we considered whether early-life family structure affects the risk of later developing gastric cancer among H. pylori+ men...
  12. ncbi request reprint Analysis of hopQ alleles in East Asian and Western strains of Helicobacter pylori
    Ping Cao
    Department of Medicine, Division of Infectious Diseases, A2200 Medical Center North, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    FEMS Microbiol Lett 251:37-43. 2005
    ..Geographic variation in the genetic characteristics of H. pylori strains may be a factor contributing to geographic variation in gastric cancer incidence...
  13. pmc Asthma is inversely associated with Helicobacter pylori status in an urban population
    Joan Reibman
    Department of Medicine, New York University School of Medicine, New York City, New York, USA
    PLoS ONE 3:e4060. 2008
    ..Since the general prevalence of Helicobacter pylori has been decreasing, we hypothesized that H. pylori serostatus would be inversely related to the presence of asthma...
  14. pmc The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin
    Fritz Francois
    New York University Langone Medical Center, New York, NY, USA
    BMC Gastroenterol 11:37. 2011
    ..pylori colonization. We prospectively evaluated the effect of H. pylori eradication on meal-associated changes in serum ghrelin and leptin levels, and body weight...
  15. pmc Molecular analysis of human forearm superficial skin bacterial biota
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 104:2927-32. 2007
    ..4% of all clones. These results show that the bacterial biota in normal superficial skin is highly diverse, with few well conserved and well represented genera, but otherwise low-level interpersonal consensus...
  16. pmc Effect of Caenorhabditis elegans age and genotype on horizontal gene transfer in intestinal bacteria
    Cynthia Portal-Celhay
    Department of Medicine, New York University Langone Medical Center, New York, New York, USA
    FASEB J 27:760-8. 2013
    ....
  17. pmc Antimutator role of the DNA glycosylase mutY gene in Helicobacter pylori
    Shuyan Huang
    Department of Microbiology and Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Bacteriol 188:6224-34. 2006
    ..Our findings indicate that H. pylori possesses phase-variable base excision repair, consistent with a tension between repair and mutation...
  18. doi request reprint Helicobacter pylori colonization is inversely associated with childhood asthma
    Yu Chen
    Department of Environmental Medicine, School of Medicine, New York University, New York, New York 10016, USA
    J Infect Dis 198:553-60. 2008
    ..Asthma, a serious health problem worldwide, is becoming more common. Colonization with Helicobacter pylori, a major human indigenous (commensal) microbe, during early life may be relevant to the risk of childhood asthma...
  19. pmc Theodore E. Woodward Award: Global warming and the human stomach: microecology follows macroecology
    Martin J Blaser
    Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Trans Am Clin Climatol Assoc 116:65-75; discussion 75-6. 2005
    ..The disappearance of H. pylori (especially cag+ strains), possibly contributing to the risk of these esophageal diseases, may be an indicator for changing human microecology...
  20. pmc Bacterial biota in reflux esophagitis and Barrett's esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    World J Gastroenterol 11:7277-83. 2005
    ..To identify the bacterial flora in conditions such as Barrettos esophagus and reflux esophagitis to determine if they are similar to normal esophageal flora...
  21. pmc Conservation and diversity of sap homologues and their organization among Campylobacter fetus isolates
    Zheng Chao Tu
    Departments of Medicine Microbiology, New York University School of Medicine Department of Veterans Affairs Medical Center, New York, New York 10016, USA
    Infect Immun 72:1715-24. 2004
    ..In total, the observed differences suggest that the sap island has evolved differing genotypes that are plastic, perhaps enabling colonization of varied niches, in addition to antigenic variation...
  22. pmc Quantitation and composition of cutaneous microbiota in diabetic and nondiabetic men
    Henry Redel
    Department of Medicine, New York University School of Medicine, New York, NY 10010, USA
    J Infect Dis 207:1105-14. 2013
    ..Diabetic foot infections are a leading cause of lower extremity amputations. Our study examines the microbiota of diabetic skin prior to ulcer development or infection...
  23. ncbi request reprint Does Helicobacter pylori protect against asthma and allergy?
    Martin J Blaser
    Department of Medicine, New York University School of Medicine, 550 First Avenue OBV A606, New York, NY 10016, USA
    Gut 57:561-7. 2008
  24. ncbi request reprint Plastic cells and populations: DNA substrate characteristics in Helicobacter pylori transformation define a flexible but conservative system for genomic variation
    Steven M Levine
    Dept of Medicine, New York University School of Medicine, New York, NY 10016, USA
    FASEB J 21:3458-67. 2007
    ..pylori population biology...
  25. pmc UvrD helicase suppresses recombination and DNA damage-induced deletions
    Josephine Kang
    Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Bacteriol 188:5450-9. 2006
    ..pylori that face high-level genotoxic stress in vivo...
  26. pmc Structural and functional divergence of MutS2 from bacterial MutS1 and eukaryotic MSH4-MSH5 homologs
    Josephine Kang
    Department of Microbiology, New York University School of Medicine, and VA Medical Center, New York, NY 10016, USA
    J Bacteriol 187:3528-37. 2005
    ..This phenotypic analysis is consistent with the phylogenetic and biochemical data suggesting that MutS1 and MutS2 have divergent functions...
  27. doi request reprint The seroprevalence of Helicobacter pylori and its relationship to malaria in Ugandan children
    Vinay Gupta
    Columbia University, College of Physicians and Surgeons, 630W 168 th Street, New York, New York 10032, USA
    Trans R Soc Trop Med Hyg 106:35-42. 2012
    ..60 (1.39-1.85), P<0.001). We observed nearly universal prevalence of CagA+ H. pylori by the age of 10 years in Kampala and found no evidence that H. pylori-positivity is protective against malaria...
  28. doi request reprint What are the consequences of the disappearing human microbiota?
    Martin J Blaser
    Department of Medicine and the Department of Microbiology, New York University Langone Medical Center, New York, New York 10017, USA
    Nat Rev Microbiol 7:887-94. 2009
    ....
  29. pmc Longitudinal analysis of serological responses of adults to Helicobacter pylori antigens
    Guillermo I Perez-Perez
    Department of Medicine, New York University Langone Medical Center, New York, New York, USA
    J Infect Dis 202:916-23. 2010
    ..These findings indicate that H. pylori-specific antibody responses are host-specific with IgG1:IgG4 ratios stable over 21 years, IgG1 responses predominating, and HspA seroconversion with aging...
  30. doi request reprint Analysis of Malassezia microbiota in healthy superficial human skin and in psoriatic lesions by multiplex real-time PCR
    Luciana C Paulino
    Department of Medicine, New York University School of Medicine, NY 10016, USA
    FEMS Yeast Res 8:460-71. 2008
    ..In accordance with our previous observations, no significant dichotomy between samples from healthy skin and from psoriatic lesions was found; the samples clustered according to the subject, rather than health status...
  31. pmc Repair and antirepair DNA helicases in Helicobacter pylori
    Josephine Kang
    Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Bacteriol 190:4218-24. 2008
    ..pylori RecG resolvase provides an "antirepair" pathway allowing for selection of varied strains. Such competition between repair and antirepair provides a novel mechanism to maximize fitness at a bacterial population level...
  32. pmc Phenotypic and genotypic variation in methylases involved in type II restriction-modification systems in Helicobacter pylori
    Tohru Takata
    Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Nucleic Acids Res 30:2444-52. 2002
    ....
  33. pmc The nonfermentable dietary fiber hydroxypropyl methylcellulose modulates intestinal microbiota
    Laura M Cox
    Department of Medicine, New York University Langone Medical Center, New York, New York, USA
    FASEB J 27:692-702. 2013
    ..This work indicates that HPMC is a potential prebiotic fiber that influences intestinal microbiota and improves host metabolism...
  34. pmc Extensive repetitive DNA facilitates prokaryotic genome plasticity
    Rahul A Aras
    Department of Medicine, New York University School of Medicine and Veterans Affairs Medical Center, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 100:13579-84. 2003
    ....
  35. pmc Effect of host species on recG phenotypes in Helicobacter pylori and Escherichia coli
    Josephine Kang
    Department of Microbiology, New York University School of Medicine, VA Medical Center, New York, New York, USA
    J Bacteriol 186:7704-13. 2004
    ..Therefore, host context appears critical in defining the function of recG. The fact that in E. coli recG phenotypes are not constant in other species indicates the diverse roles for conserved recombination genes in prokaryotic evolution...
  36. ncbi request reprint A Helicobacter pylori restriction endonuclease-replacing gene, hrgA, is associated with gastric cancer in Asian strains
    Takafumi Ando
    Departments of Medicine and Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Cancer Res 62:2385-9. 2002
    ..Although a direct function for hrgA in virulence could not be demonstrated, our data indicate that hrgA is a strain-specific gene that might be associated with gastric cancer among H. pylori isolates from Asian patients...
  37. pmc The effect of laparoscopic gastric banding surgery on plasma levels of appetite-control, insulinotropic, and digestive hormones
    Joshua R Shak
    Department of Medicine, NYU School of Medicine, New York, NY, USA
    Obes Surg 18:1089-96. 2008
    ..To examine this hypothesis, we determined plasma concentrations of appetite-control, insulinotropic, and digestive hormones in relation to LAGB...
  38. pmc Natural transformation of helicobacter pylori involves the integration of short DNA fragments interrupted by gaps of variable size
    Edward A Lin
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS Pathog 5:e1000337. 2009
    ..Taken together, these observations support a system of highly efficient short-fragment recombination involving multiple recombination events within a single locus...
  39. ncbi request reprint Mechanisms underlying Campylobacter fetus pathogenesis in humans: surface-layer protein variation in relapsing infections
    Zheng Chao Tu
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Infect Dis 191:2082-9. 2005
    ..In total, these findings indicate that relapse may reflect at least 3 differing pathogenetic pathways...
  40. pmc Genetic divergence of Campylobacter fetus strains of mammal and reptile origins
    Zheng Chao Tu
    Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Microbiol 43:3334-40. 2005
    ..Diagnostic tools have been developed to differentiate among C. fetus isolates for taxonomic and epidemiologic uses...
  41. pmc Quantitation of major human cutaneous bacterial and fungal populations
    Zhan Gao
    Department of Medicine, New York University Langone Medical Center, New York, New York 10016, USA
    J Clin Microbiol 48:3575-81. 2010
    ..These results provide the first quantitation of the site and host specificities of major bacterial and fungal populations in human skin and present simple methods for their assessment in studies of disease...
  42. pmc Competition and resilience between founder and introduced bacteria in the Caenorhabditis elegans gut
    Cynthia Portal-Celhay
    Department of Medicine and Microbiology, New York University School of Medicine, New York, New York, USA
    Infect Immun 80:1288-99. 2012
    ..coli strain and against Salmonella. Our data provide evidence of active competition for colonization niches in the C. elegans gut, as determined by bacterial factors and subject to in vivo selection...
  43. ncbi request reprint Helicobacter pylori and overweight status in the United States: data from the Third National Health and Nutrition Examination Survey
    Ilseung Cho
    Department of Medicine, New York University School of Medicine, New York, NY, USA
    Am J Epidemiol 162:579-84. 2005
    ..pylori groups. In this US population-based study, there was no significant association between H. pylori colonization, cagA+ strains of H. pylori, and being overweight...
  44. ncbi request reprint Structure and genotypic plasticity of the Campylobacter fetus sap locus
    Zheng Chao Tu
    Division of Infectious Diseases, Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Mol Microbiol 48:685-98. 2003
    ..As divergent SLP C-termini possess multiple antigenic sites, their reciprocal recombination behind the unique sap promoter leads to continuing antigenic variation...
  45. ncbi request reprint Role of dprA in transformation of Campylobacter jejuni
    Tohru Takata
    Department of Medicine, New York University School of Medicine, New York, NY, USA
    FEMS Microbiol Lett 252:161-8. 2005
    ..pylori>H. influenzae) restored electro-transformation. Thus, C. jejuni expresses a DprA ortholog that functionally most closely resembles that of H. pylori and is involved in DNA transformation...
  46. ncbi request reprint Inhibition of Bacillus anthracis growth and virulence-gene expression by inhibitors of quorum-sensing
    Marcus B Jones
    Department of Microbiology, Sackler Institute, and Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Infect Dis 191:1881-8. 2005
    ..These data suggest that use of QS inhibitors could represent novel therapies for anthrax...
  47. pmc Host-dependent Lewis (Le) antigen expression in Helicobacter pylori cells recovered from Leb-transgenic mice
    Mary Ann Pohl
    Department of Medicine, New York University School of Medicine and Veteran s Administration Medical Center, New York, NY 10016, USA
    J Exp Med 206:3061-72. 2009
    ..These studies indicate that H. pylori evolves to resemble the host's gastric Le phenotype, and reveal a bacterial genetic locus that is subject to host-driven selection pressure...
  48. ncbi request reprint A paradigm for direct stress-induced mutation in prokaryotes
    Josephine M Kang
    Department of Medicine, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA
    FASEB J 20:2476-85. 2006
    ..These studies provide a new paradigm for adaptation under increased selective pressures that may be present in other prokaryotes...
  49. pmc Transient and persistent Helicobacter pylori colonization in Native American children
    Guillermo I Perez-Perez
    Division of Infectious Diseases, Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Clin Microbiol 41:2401-7. 2003
    ..pylori-negative children. Thus, H. pylori acquisition, accompanied by a transient PGI increase, was frequent in this population, especially in the second and third years of life, but often was brief...
  50. ncbi request reprint An endangered species in the stomach
    Martin J Blaser
    Department of Medicine, New York University School of Medicine, USA
    Sci Am 292:38-45. 2005
  51. pmc Plasticity of repetitive DNA sequences within a bacterial (Type IV) secretion system component
    Rahul A Aras
    Department of Medicine, New York University School of Medicine, and VA Medical Center, NY 10016, USA
    J Exp Med 198:1349-60. 2003
    ..Using repetitive DNA, H. pylori rearrangements in a host-exposed subunit of a conserved bacterial secretion system may permit a novel form of antigenic evasion...
  52. pmc Role of futC slipped strand mispairing in Helicobacter pylori Lewisy phase variation
    Edgardo Sanabria-Valentín
    Department of Microbiology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Microbes Infect 9:1553-60. 2007
    ..Le(y) synthesis was restored and Le(x) expression was reciprocally lowered. From these studies, we confirmed the principal role of futC slipped-strand mispairing in Le antigenic variation in vitro and in vivo...
  53. pmc Association between oral health and gastric precancerous lesions
    Christian R Salazar
    Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY 10003, USA
    Carcinogenesis 33:399-403. 2012
    ..7%)], independent of potential confounders. Our findings demonstrate that specific oral health conditions and behaviors such as gingival bleeding and tooth flossing are associated with gastric precancerous lesions...
  54. pmc East Asian genotypes of Helicobacter pylori strains in Amerindians provide evidence for its ancient human carriage
    Chandrabali Ghose
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 99:15107-11. 2002
    ..These findings provide evidence that H. pylori has been present in humans at least since ancestors of Amerindians migrated from Asia more than 11,000 years ago...
  55. pmc Molecular analysis of fungal microbiota in samples from healthy human skin and psoriatic lesions
    Luciana C Paulino
    Department of Medicine, New York University School of Medicine, 550 First Ave, OBV A 606, New York, NY 10016, USA
    J Clin Microbiol 44:2933-41. 2006
    ..These data indicate the predominance of Malassezia organisms in healthy human skin, host-specific variation, stability over time, and as yet, no consistent patterns differentiating psoriatic skin from healthy skin...
  56. pmc Antibiotics in early life alter the murine colonic microbiome and adiposity
    Ilseung Cho
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    Nature 488:621-6. 2012
    ..In this model, we demonstrate the alteration of early-life murine metabolic homeostasis through antibiotic manipulation...
  57. pmc DprB facilitates inter- and intragenomic recombination in Helicobacter pylori
    Xue Song Zhang
    Department of Medicine, New York University School of Medicine, New York, New York, USA
    J Bacteriol 194:3891-903. 2012
    ..We provide evidence that the two putative H. pylori HJRs (DprB and RuvC) have overlapping but distinct functions involving intergenomic (primarily DprB) and intragenomic (primarily RuvC) recombination...
  58. pmc Evidence of host-virus co-evolution in tetranucleotide usage patterns of bacteriophages and eukaryotic viruses
    David T Pride
    Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    BMC Genomics 7:8. 2006
    ..Tetranucleotide usage deviation (TUD) patterns were chosen since they have previously been shown to contain phylogenetic signal similar to that of 16S rRNA...
  59. ncbi request reprint Matrix metalloproteinase secretion by gastric epithelial cells is regulated by E prostaglandins and MAPKs
    Michael H Pillinger
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Biol Chem 280:9973-9. 2005
    ..pylori infection and/or cyclooxygenase inhibition may induce epithelial cell signaling to contribute to gastric ulcerogenesis...
  60. ncbi request reprint The language used by Helicobacter pylori to regulate human cells
    Michael H Pillinger
    Department of Medicine, New York University School of Medicine, New York, NY 10010, USA
    J Infect Dis 196:6-9. 2007
  61. pmc Campylobacter fetus of reptile origin as a human pathogen
    Zheng Chao Tu
    Department of Medicine, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA
    J Clin Microbiol 42:4405-7. 2004
    ..Although phenotypic testing did not definitively identify the organisms, molecular analysis indicated that they were the same strain of Campylobacter fetus subsp. fetus and were of reptile origin...
  62. pmc Genotypic and phenotypic variation of Lewis antigen expression in geographically diverse Helicobacter pylori isolates
    Mary Ann Pohl
    Department of Medicine, New York University School of Medicine, New York, NY, USA
    Helicobacter 16:475-81. 2011
    ..pylori by variation at the Le synthesis loci. In this report, we sought to characterize Le genotypic and phenotypic variation in geographically diverse H. pylori isolates...
  63. pmc Natural transformation of an engineered Helicobacter pylori strain deficient in type II restriction endonucleases
    Xue Song Zhang
    Department of Medicine, New York University School of Medicine and VA Medical Center, New York, New York, USA
    J Bacteriol 194:3407-16. 2012
    ..In total, the data indicate that the type II REd mutant has enhanced competence with no loss of growth or repair facility compared to the wild type, facilitating H. pylori mutant construction and other genetic engineering...
  64. pmc Association between gastric Helicobacter pylori colonization and glycated hemoglobin levels
    Yu Chen
    Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA
    J Infect Dis 205:1195-202. 2012
    ..Few studies have evaluated the potential influence of Helicobacter pylori on biomarkers for diabetes...
  65. pmc Helicobacter pylori interstrain restriction-modification diversity prevents genome subversion by chromosomal DNA from competing strains
    Rahul A Aras
    Department of Medicine and Microbiology, New York University School of Medicine and VA Medical Center, New York, NY, USA
    Nucleic Acids Res 30:5391-7. 2002
    ..pylori R-M diversity limits acquisition of chromosomal DNA fragments of >/=1 kb...
  66. pmc Helicobacter pylori persistence: biology and disease
    Martin J Blaser
    Department of Medicine, New York University School of Medicine, and New York Harbor Veterans Affairs Medical Center, New York 10016, USA
    J Clin Invest 113:321-33. 2004
    ..A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia...
  67. pmc Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans
    Cynthia Portal-Celhay
    Department of Medicine, New York University School of Medicine, NYU Langone Medical Center, 550 First Avenue, OBV A606, New York, NY 10016, USA
    BMC Microbiol 12:49. 2012
    ..To address this question, we evaluated the ability of worms to control bacterial accumulation as a functional marker of intestinal immunity...
  68. pmc Helicobacter pylori in health and disease
    Timothy L Cover
    Department of Medicine, Vanderbilt University School of Medicine and Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee 37232, USA
    Gastroenterology 136:1863-73. 2009
    ....
  69. pmc Who are we? Indigenous microbes and the ecology of human diseases
    Martin J Blaser
    Internal Medicine, Department of Medicine, Microbiology at New York University School of Medicine, New York, USA
    EMBO Rep 7:956-60. 2006
  70. pmc The human microbiome: at the interface of health and disease
    Ilseung Cho
    Department of Medicine, NYU Langone Medical Center, New York, New York 10016, USA
    Nat Rev Genet 13:260-70. 2012
    ..Both the microbiome and metagenome probably have important functions in health and disease; their exploration is a frontier in human genetics...