Florian Bassermann

Summary

Affiliation: New York University
Country: USA

Publications

  1. ncbi Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany, and Department of Pathology, St Jude Chidren s Research Hospital, Memphis, TN 38105, USA
    J Biol Chem 282:15965-72. 2007
  2. ncbi Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA)
    Tao Ouyang
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 278:30028-36. 2003
  3. ncbi NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany
    Cell 122:45-57. 2005
  4. ncbi Phosphorylation of grb10 regulates its interaction with 14-3-3
    Susanne Urschel
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 280:16987-93. 2005
  5. pmc Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M
    Anna Lena Illert
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 287:37997-8005. 2012
  6. pmc APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1
    Christine von Klitzing
    Department of Internal Medicine ΙΙΙ, Technical University of Munich, Munich, Germany
    PLoS ONE 6:e28998. 2011
  7. pmc Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase
    Anna Lena Illert
    Department of Internal Medicine III, Technical University of Munich, Munich 81675, Germany
    Development 139:2523-34. 2012
  8. ncbi Mitotic entry: a matter of oscillating destruction
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, Munich, Germany
    Cell Cycle 4:1515-7. 2005
  9. ncbi Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway
    Florian Bassermann
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675, Germany
    J Biol Chem 277:12437-45. 2002
  10. ncbi SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma
    Vanesa Fernández-Sáiz
    Department of Medicine III, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Nat Cell Biol 15:72-81. 2013

Collaborators

  • Michele Pagano
  • Christian Peschel
  • Justus Duyster
  • Ren Yuan Bai
  • Marco Barchi
  • Florian Lordick
  • Thomas Jahn
  • Andreas Sendler
  • Verena Voelter
  • Anna Lena Illert
  • Christine von Klitzing
  • Vanesa Fernández-Sáiz
  • Stephan W Morris
  • Luca Busino
  • David Frescas
  • Kathrin Abbrederis
  • Susanne Urschel
  • Tao Ouyang
  • Anna Maria Knorn
  • Bernhard Kuster
  • Simone Lemeer
  • Ruth Eichner
  • Christian Langer
  • Lars Bullinger
  • Sonja Schroeder
  • Julia Slotta-Huspenina
  • Julia Kurutz
  • Clemens Reiter
  • Bianca Sabrina Targosz
  • Mitsuteru Hiwatari
  • Cristina Antinozzi
  • Hiroyuki Kawaguchi
  • Letitia Quintanilla-Martinez
  • Corinna Albers
  • Michael Zech
  • Dirk G de Rooij
  • Stefanie Kreutmair
  • Cathrin Moll
  • Richard Huss
  • Sabine Wötzel
  • Astrid Fröschl
  • Giulio F Draetta
  • Sofia I H Godinho
  • Ryo Koyama-Nasu
  • Alessio Maiolica
  • Choogon Lee
  • Daniele Guardavaccaro
  • Patrick M Nolan
  • Raymonde Busch
  • Nadine Roethling
  • Christoph Schuhmacher
  • Joerg R Siewert
  • Silvia Münch
  • Silvia Klumpen
  • Cornelius Miething

Detail Information

Publications14

  1. ncbi Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany, and Department of Pathology, St Jude Chidren s Research Hospital, Memphis, TN 38105, USA
    J Biol Chem 282:15965-72. 2007
    ..Thus, cyclin B1/Cdk1 may contribute to the regulation of its own abundance in early mitosis...
  2. ncbi Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA)
    Tao Ouyang
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 278:30028-36. 2003
    ..These results implicate an antiapoptotic role for NIPA in NPM-ALK-mediated signaling events...
  3. ncbi NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany
    Cell 122:45-57. 2005
    ..Thus, SCF(NIPA)-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle...
  4. ncbi Phosphorylation of grb10 regulates its interaction with 14-3-3
    Susanne Urschel
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 280:16987-93. 2005
    ..Based on these findings, we propose a regulatory circuitry involving a phosphorylation-regulated complex formation of Grb10 with 14-3-3 and Akt...
  5. pmc Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M
    Anna Lena Illert
    Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany
    J Biol Chem 287:37997-8005. 2012
    ..Thus, our data add to the recently described divergent functions of ERK1 and ERK2 in cell cycle regulation, which may be due in part to the differential ability of these kinases to phosphorylate and inactivate NIPA at G(2)/M...
  6. pmc APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1
    Christine von Klitzing
    Department of Internal Medicine ΙΙΙ, Technical University of Munich, Munich, Germany
    PLoS ONE 6:e28998. 2011
    ..Our data thus define a novel mode of regulating APC/C-mediated ubiquitination...
  7. pmc Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase
    Anna Lena Illert
    Department of Internal Medicine III, Technical University of Munich, Munich 81675, Germany
    Development 139:2523-34. 2012
    ..Moreover, we show nuclear accumulation of cyclin B1 with a subsequent premature increase in G2/M kinase activity in Nipa-/- spermatocytes. Together, these results reveal a novel role for NIPA in meiosis...
  8. ncbi Mitotic entry: a matter of oscillating destruction
    Florian Bassermann
    Department of Internal Medicine III, Technical University of Munich, Munich, Germany
    Cell Cycle 4:1515-7. 2005
    ..Thus, oscillating ubiquitination of nuclear cyclin B1 driven by the SCFNIPA complex contributes to the timing of mitotic entry in the mammalian cell cycle...
  9. ncbi Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway
    Florian Bassermann
    Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675, Germany
    J Biol Chem 277:12437-45. 2002
    ....
  10. ncbi SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma
    Vanesa Fernández-Sáiz
    Department of Medicine III, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Nat Cell Biol 15:72-81. 2013
    ....
  11. ncbi Erythropoietin-alfa during neoadjuvant chemotherapy for locally advanced esophagogastric adenocarcinoma
    Kathrin Abbrederis
    Third Department of Medicine Hematology Oncology, Institute for Medical Statistics and Epidemiology, and Munich Center for Clinical Studies, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
    Ann Thorac Surg 82:293-7. 2006
    ..In a previous study we showed that many patients with esophagogastric adenocarcinoma experience anemia during neoadjuvant chemotherapy. We now investigated the role of erythropoietin in managing anemia during neoadjuvant chemotherapy...
  12. ncbi SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
    Luca Busino
    Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, NY 10016, USA
    Science 316:900-4. 2007
    ..Silencing of Fbxl3 produced no effect in Cry1-/-;Cry2-/- cells, which shows that Fbxl3 controls clock oscillations by mediating the degradation of CRY proteins...
  13. pmc The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
    Florian Bassermann
    Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, NY 10016, USA
    Cell 134:256-67. 2008
    ..These findings define a novel pathway that is crucial for the G2 DNA-damage-response checkpoint...
  14. ncbi JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes
    David Frescas
    Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, New York, New York 10016, USA
    Nature 450:309-13. 2007
    ....