Research Topics
Genomes and Genes
| Florian BassermannSummaryAffiliation: New York University Country: USA Publications
| Collaborators
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Detail Information
Publications
Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1Florian Bassermann
Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany, and Department of Pathology, St Jude Chidren s Research Hospital, Memphis, TN 38105, USA
J Biol Chem 282:15965-72. 2007..Thus, cyclin B1/Cdk1 may contribute to the regulation of its own abundance in early mitosis...
Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA)Tao Ouyang
Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
J Biol Chem 278:30028-36. 2003..These results implicate an antiapoptotic role for NIPA in NPM-ALK-mediated signaling events...
NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entryFlorian Bassermann
Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany
Cell 122:45-57. 2005..Thus, SCF(NIPA)-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle...
Phosphorylation of grb10 regulates its interaction with 14-3-3Susanne Urschel
Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675 Munich, Germany
J Biol Chem 280:16987-93. 2005..Based on these findings, we propose a regulatory circuitry involving a phosphorylation-regulated complex formation of Grb10 with 14-3-3 and Akt...
APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1Christine von Klitzing
Department of Internal Medicine ΙΙΙ, Technical University of Munich, Munich, Germany
PLoS ONE 6:e28998. 2011..Our data thus define a novel mode of regulating APC/C-mediated ubiquitination...
Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophaseAnna Lena Illert
Department of Internal Medicine III, Technical University of Munich, Munich 81675, Germany
Development 139:2523-34. 2012..Moreover, we show nuclear accumulation of cyclin B1 with a subsequent premature increase in G2/M kinase activity in Nipa-/- spermatocytes. Together, these results reveal a novel role for NIPA in meiosis...
Mitotic entry: a matter of oscillating destructionFlorian Bassermann
Department of Internal Medicine III, Technical University of Munich, Munich, Germany
Cell Cycle 4:1515-7. 2005..Thus, oscillating ubiquitination of nuclear cyclin B1 driven by the SCFNIPA complex contributes to the timing of mitotic entry in the mammalian cell cycle...
Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathwayFlorian Bassermann
Department of Internal Medicine III, Laboratory of Leukemogenesis, Technical University of Munich, 81675, Germany
J Biol Chem 277:12437-45. 2002....
Erythropoietin-alfa during neoadjuvant chemotherapy for locally advanced esophagogastric adenocarcinomaKathrin Abbrederis
Third Department of Medicine (Hematology/Oncology, Institute for Medical Statistics and Epidemiology, and Munich Center for Clinical Studies, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
Ann Thorac Surg 82:293-7. 2006..There were no erythropoietin-related adverse events. CONCLUSIONS: Treatment with erythropoietin is effective and well tolerated in patients with esophagogastric adenocarcinoma who experience anemia during neoadjuvant chemotherapy...
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteinsLuca Busino
Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, NY 10016, USA
Science 316:900-4. 2007..Silencing of Fbxl3 produced no effect in Cry1-/-;Cry2-/- cells, which shows that Fbxl3 controls clock oscillations by mediating the degradation of CRY proteins...
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genesDavid Frescas
Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, New York, New York 10016, USA
Nature 450:309-13. 2007....
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpointFlorian Bassermann
Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, NY 10016, USA
Cell 134:256-67. 2008..These findings define a novel pathway that is crucial for the G2 DNA-damage-response checkpoint...
