Affiliation: New Jersey
Aviv A. Telomeres, sex, reactive oxygen species, and human cardiovascular aging. J Mol Med (Berl). 2002;80:689-95 pubmed
..In the final analysis, the biology of reactive oxygen species may offer a common explanation for some interindividual variation in cardiovascular aging and age-dependent telomere attrition in humans. ..
Aviv A, Levy D. Telomeres, atherosclerosis, and the hemothelium: the longer view. Annu Rev Med. 2012;63:293-301 pubmed publisher
..Our model comes down to this proposition: Shortened LTL predicts increased atherosclerotic risk because the injurious component of atherosclerosis exceeds the repair capacity of HSC reserves, which largely depend on HSC telomere length. ..
Aviv A, Chen W, Gardner J, Kimura M, Brimacombe M, Cao X, et al
. Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol. 2009;169:323-9 pubmed publisher
..These findings underscore the complexity of leukocyte telomere dynamics in vivo and suggest that determinants in addition to the "end-replication problem" contribute to telomere shortening in vivo. ..
Aviv A. Genetics of leukocyte telomere length and its role in atherosclerosis. Mutat Res. 2012;730:68-74 pubmed publisher
..The mechanisms underlying these associations are still not well understood, but they stem in part from genetic factors in control of telomere maintenance and the rate of HSC replication. ..
Aviv A, Hunt S, Lin J, Cao X, Kimura M, Blackburn E. Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR. Nucleic Acids Res. 2011;39:e134 pubmed publisher
..We discuss the ramifications of these findings with regard to measurements of telomere length/DNA content in epidemiological/clinical circumstances. ..
Aviv A, Hollenberg N, Weder A. Urinary potassium excretion and sodium sensitivity in blacks. Hypertension. 2004;43:707-13 pubmed
..In this sense, the biological implication of sodium sensitivity in blacks and in humans in general has ramifications above and beyond salt-evoked increase in blood pressure. ..
Aviv A, Susser E. Leukocyte telomere length and the father's age enigma: implications for population health and for life course. Int J Epidemiol. 2013;42:457-62 pubmed publisher
..We draw together work across a range of disciplines to offer an integrated perspective of this issue. ..