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Optical mapping and its potential for large-scale sequencing projectsC Aston
Wyeth Ayerst Research, CNS Disorders, Princeton, NJ 08543, USA
Trends Biotechnol 17:297-302. 1999..Such optical maps can be constructed from both large-insert clones and genomic DNA, and are used as a scaffold for accurately aligning sequence contigs generated by shotgun sequencing...
