Research Topics
| L A AdlerSummaryAffiliation: New York University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Atomoxetine treatment outcomes in adolescents and young adults with attention-deficit/hyperactivity disorder: results from a post hoc, pooled analysisLenard A Adler
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Clin Ther 34:363-73. 2012..As a first step, we present the results of a post hoc, pooled analysis that compared the efficacy and safety profile of atomoxetine in these 2 patient populations...
A randomized controlled trial of a novel mixed monoamine reuptake inhibitor in adults with ADHDTimothy E Wilens
Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Behav Brain Funct 4:24. 2008..abstract:..
Attention-deficit/hyperactivity disorder in adult patients with posttraumatic stress disorder (PTSD): is ADHD a vulnerability factor?L A Adler
New York University School of Medicine, NY 10016, USA
J Atten Disord 8:11-6. 2004..This study examined the association between PTSD and ADHD using retrospective and current clinical evaluations...
Validity of pilot Adult ADHD Self- Report Scale (ASRS) to Rate Adult ADHD symptomsLenard A Adler
Department of Psychiatry and Neurology, Adult ADHD Program, NYU School of Medicine, New York, NY 10016, USA
Ann Clin Psychiatry 18:145-8. 2006..The goal of this study was to validate the pilot Adult ADHD Self-Report Scale (pilot ASRS) versus standard clinician ratings on the ADHD Rating Scale (ADHD RS)...
Combination pharmacotherapy for adult ADHDLenard A Adler
Faculty Practice Offices, NYU School of Medicine, 530 First Avenue, New York, NY 10016, USA
Curr Psychiatry Rep 8:409-15. 2006..Adjunct treatment of mirtazapine to stimulant medications reduced associated insomnia. These data support previous research that validates the use of combination pharmacotherapy for adults with ADHD...
Quality of life assessment in adult patients with attention-deficit/hyperactivity disorder treated with atomoxetineLenard A Adler
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
J Clin Psychopharmacol 26:648-52. 2006..Despite the existence of research demonstrating the effects of ADHD on certain aspects of life, the clinical trials of treatments for this disorder have focused primarily on efficacy and safety...
Once-daily atomoxetine for adult attention-deficit/hyperactivity disorder: a 6-month, double-blind trialLenard A Adler
NYU School of Medicine, New York VA Harbor Healthcare System, New York, NY 10016, USA
J Clin Psychopharmacol 29:44-50. 2009..Atomoxetine demonstrated significant efficacy that continued into the evening. Adverse events were similar to previous trials...
Double-blind, placebo-controlled study of the efficacy and safety of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorderLenard A Adler
Department of Psychiatry, New York University School of Medicine, 530 First Ave 7D, New York, NY 10016, USA
J Clin Psychiatry 69:1364-73. 2008..To evaluate the efficacy and safety of 30, 50, and 70 mg/day lisdexamfetamine dimesylate compared with placebo in adults with attention-deficit/hyperactivity disorder (ADHD)...
Functional outcomes in the treatment of adults with ADHDLenard A Adler
Department of Psychiatry, New York University School of Medicine, New York, NY 10010, USA
J Atten Disord 11:720-7. 2008..ADHD is associated with significant functional impairment in adults. The present study examined functional outcomes following 6-month double-blind treatment with either atomoxetine or placebo...
The reliability and validity of self- and investigator ratings of ADHD in adultsLenard A Adler
New York University School of Medicine, New York, NY 10016, USA
J Atten Disord 11:711-9. 2008....
Efficacy and safety of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled, double-blind, parallel group, dose-escalation studyLenard A Adler
NYU School of Medicine, New York VA Harbor Healthcare System, New York, NY 10016, USA
J Clin Psychopharmacol 29:239-47. 2009..To assess the efficacy and safety of OROS methylphenidate (Concerta; McNeil Pediatrics Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc, Titusville, NJ) in the management of attention-deficit/hyperactivity disorder (ADHD) in adults...
Retrospective safety analysis of atomoxetine in adult ADHD patients with or without comorbid alcohol abuse and dependenceLenard Adler
Department of Psychiatry and Child and Adolescent Psychiatry, New York University Langone School of Medicine, 530 First Avenue, 7D, New York NY 10016, USA
Am J Addict 18:393-401. 2009..Vital signs and measures of hepatic function were not significantly different among the 3 drinking status groups taking atomoxetine...
Management of ADHD in adultsLenard A Adler
Department of Clinical Psychiatry and Neurology, New York University School of Medicine, 530 First Avenue, Suite 5A, New York, NY 10016, USA
J Clin Psychiatry 63:29-35. 2002..This article reviews the history, neurobiology, and pharmacologic management of adult ADHD...
Clinical presentations of adult patients with ADHDLenard A Adler
Combined Psychiatry and Neurology Adult ADHD Program, New York University School of Medicine, New York 10016, USA
J Clin Psychiatry 65:8-11. 2004..These reports also stress the high probability of comorbid disorders and family aggregation of ADHD, as well as the likelihood that the adult with ADHD has developed coping mechanisms to compensate for his or her impairment...
Long-term, open-label safety and efficacy of atomoxetine in adults with ADHD: final report of a 4-year studyLenard A Adler
New York University, School of Medicine, New York, NY 10016, USA
J Atten Disord 12:248-53. 2008..Previously, data from 97 weeks of open-label atomoxetine treatment of adults with attention-deficit/hyperactivity disorder (ADHD) were reported. This final report of that study presents results from over 4 years of treatment...
Diagnosis and evaluation of adults with attention-deficit/hyperactivity disorderLenard Adler
Department of Psychiatry, New York University School of Medicine, FPO Offices, 530 First Avenue, Suite 5A, New York, NY 10016, USA
Psychiatr Clin North Am 27:187-201. 2004..Accordingly, adult ADHD remains a clinical diagnosis, and the clinician-administered interview remains the cornerstone of diagnostic evaluation...
Long-term effectiveness and safety of dexmethylphenidate extended-release capsules in adult ADHDLenard A Adler
New York University School of Medicine, New York, NY 10016, USA
J Atten Disord 12:449-59. 2009..This study evaluates dexmethylphenidate extended release (d-MPH-ER) in adults with ADHD...
Training raters to assess adult ADHD: reliability of ratingsLenard A Adler
New York University School of Medicine, New York, NY 10016, USA
J Atten Disord 8:121-6. 2005..For the ADHDRS-IV-Inv, rater agreement was moderate, and reliability, as measured by Cronbach's alpha, was substantial. The data indicate that clinicians can be trained to reliably evaluate ADHD in adults using the ADHDRS-IV-Inv...
Emotional dysregulation in adult ADHD and response to atomoxetineFrederick W Reimherr
Mood Disorders Clinic, Department of Psychiatry, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Biol Psychiatry 58:125-31. 2005....
Safety and tolerability of once versus twice daily atomoxetine in adults with ADHDLenard Adler
School of Medicine, New York University, New York, NY, USA
Ann Clin Psychiatry 18:107-13. 2006..Changes in dosing strategy are unlikely to be accompanied by safety risks, implying that there is room for prescribers to use discretion and to base dosing strategies on individual factors...
Long-term safety and effectiveness of lisdexamfetamine dimesylate in adults with attention-deficit/ hyperactivity disorderRichard Weisler
Department of Psychiatry, University of North Carolina, Chapel Hill, USA
CNS Spectr 14:573-85. 2009..To evaluate the long-term safety and effectiveness of lisdexamfetamine dimesylate (LDX) in the treatment of adults with attention-deficit/hyperactivity disorder (ADHD)...
Genetic polymorphisms in the treatment of depression: speculations from an augmentation study using atomoxetineFrederick Reimherr
Department of Psychiatry, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
Psychiatry Res 175:67-73. 2010..Although this study is speculative, it represents a pharmacologically and genotypically well-defined patient population...
Epidemiology, impairments, and differential diagnosis in adult ADHD: introductionLenard A Adler
CNS Spectr 13:4-5. 2008
ABT-089, a neuronal nicotinic receptor partial agonist, for the treatment of attention-deficit/hyperactivity disorder in adults: results of a pilot studyTimothy E Wilens
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Biol Psychiatry 59:1065-70. 2006..This pilot study was designed to evaluate ABT-089, a neuronal nicotinic receptor partial agonist, as treatment for adult attention-deficit/hyperactivity disorder (ADHD)...
Atomoxetine treatment of adults with ADHD and comorbid alcohol use disordersTimothy E Wilens
Massachusetts General Hospital, 55 Fruit Street, YAW 6900, Boston, MA 02114, USA
Drug Alcohol Depend 96:145-54. 2008..The study aim was to determine if atomoxetine was superior to placebo in improving ADHD and alcohol use in recently abstinent adults with ADHD and comorbid alcohol use disorder...
Gender differences in 2 clinical trials of adults with attention-deficit/hyperactivity disorder: a retrospective data analysisReid J Robison
Mood Disorders Clinic, Department of Psychiatry, University of Utah, Salt Lake City, UT 84132, USA
J Clin Psychiatry 69:213-21. 2008....
Assessing attention-deficit/hyperactivity disorder in adults: focus on rating scalesKevin R Murphy
Adult ADHD Clinic of Central Massachusetts, Northboro 01532, USA
J Clin Psychiatry 65:12-7. 2004..1 Symptom Checklist. More research is needed to establish the usefulness of self-administered rating scales compared with investigator-administered scales in the assessment and diagnosis of adult ADHD...
Long-term, open-label study of the safety and efficacy of atomoxetine in adults with attention-deficit/hyperactivity disorder: an interim analysisLenard A Adler
New York University, New York, USA
J Clin Psychiatry 66:294-9. 2005..CONCLUSION: The results of this interim analysis of an ongoing, open-label study of adults with ADHD support the long-term efficacy, safety, and tolerability of atomoxetine for the treatment of adult ADHD...
Patterns and predictors of attention-deficit/hyperactivity disorder persistence into adulthood: results from the national comorbidity survey replicationRonald C Kessler
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
Biol Psychiatry 57:1442-51. 2005..Despite growing interest in adult attention-deficit/hyperactivity disorder (ADHD), little is known about predictors of persistence of childhood cases into adulthood...
Atomoxetine and adult attention-deficit/hyperactivity disorder: the effects of comorbidityThomas J Spencer
Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, USA
J Clin Psychiatry 67:415-20. 2006....
Efficacy and safety of dexmethylphenidate extended-release capsules in adults with attention-deficit/hyperactivity disorderThomas J Spencer
Pediatric Psychopharmacology Research Clinic, Massachusetts General Hospital, Boston, Massachusetts 02114, and New York University School of Medicine, New York, NY, USA
Biol Psychiatry 61:1380-7. 2007..This multicenter, randomized, fixed-dose, double-blind, placebo-controlled study evaluated efficacy of extended-release dexmethylphenidate (d-MPH-ER) in adults with attention-deficit/hyperactivity disorder (ADHD)...
Addition of atomoxetine for depression incompletely responsive to sertraline: a randomized, double-blind, placebo-controlled studyDavid Michelson
Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, Ind, USA
J Clin Psychiatry 68:582-7. 2007..Addition of a noradrenergic intervention in patients poorly or partially responsive to SSRIs may improve outcomes, but few well-controlled studies testing this hypothesis have been reported...
Validity of the World Health Organization Adult ADHD Self-Report Scale (ASRS) Screener in a representative sample of health plan membersRonald C Kessler
Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
Int J Methods Psychiatr Res 16:52-65. 2007..90. The brevity and ability to discriminate DSM-IV cases from non-cases make the six-question ASRS Screener attractive for use both in community epidemiological surveys and in clinical outreach and case-finding initiatives...
Non-stimulant trials of adult ADHDLenard A Adler
Adult ADHD Program, New York University School of Medicine, New York City, New York, USA
CNS Spectr 12:11-3. 2007
Familial transmission of ADHD and psychoactive substance use disordersLenard A Adler
Am J Psychiatry 165:11-2. 2008
The impact, identification, and management of attention-deficit/hyperactivity disorder in adults. IntroductionLenard A Adler
New York University Medical Center, New York, NY, USA
CNS Spectr 12:1-2. 2007
Misuse and diversion of stimulants prescribed for ADHD: a systematic review of the literatureTimothy E Wilens
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Am Acad Child Adolesc Psychiatry 47:21-31. 2008..The purpose of this systematic review of the literature is to evaluate the extent and characteristics of stimulant misuse and diversion in attention-deficit/hyperactivity disorder (ADHD) and non-ADHD individuals...
Functional and psychosocial impairment in adults with undiagnosed ADHDStephen L Able
US Outcomes Research, Lilly Research Laboratories, Indianapolis, IN 46285, USA
Psychol Med 37:97-107. 2007..Additionally, compare adults with undiagnosed and diagnosed ADHD to investigate possible reasons why the undiagnosed avoid clinical detection...
From childhood into adulthood: the changing face of ADHDLenard A Adler
New York University Medical Center, New York, New York, USA
CNS Spectr 12:6-9. 2007
Treatment predictors of extrapyramidal side effects in patients with tardive dyskinesia: results from Veterans Affairs Cooperative Study 394James B Lohr
Psychiatry Service, San Diego Department of Veterans Affairs Medical Center, California 92161, USA
J Clin Psychopharmacol 22:196-200. 2002..These findings indicate that clinician-modifiable factors related to medication usage can influence the outcome of TD and EPS in patients with persistent TD...
Network homogeneity reveals decreased integrity of default-mode network in ADHDLucina Q Uddin
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
J Neurosci Methods 169:249-54. 2008..Network homogeneity provides a potential alternative method for assessing functional connectivity of specific large-scale networks in clinical populations...
Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorderF Xavier Castellanos
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Biol Psychiatry 63:332-7. 2008....
