D Maciejewski-Lenoir

Summary

Affiliation: Neurocrine Biosciences

Country: USA

Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia
D Maciejewski-Lenoir
Neurocrine Biosciences Inc, San Diego, CA 92121, USA
J Immunol 163:1628-35. 1999
Selective impairment of corticotropin-releasing factor1 (CRF1) receptor-mediated function using CRF coupled to saporin
D Maciejewski-Lenoir
Neurocrine Biosciences, Inc, San Diego, California 92121, USA
Endocrinology 141:498-504. 2000
The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia
S A Boehme
Neurocrine Biosciences, Inc, San Diego, CA 92121, USA
J Immunol 165:397-403. 2000

Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia
D Maciejewski-Lenoir
Neurocrine Biosciences Inc, San Diego, CA 92121, USA
J Immunol 163:1628-35. 1999
..However, the activity of this chemokine on astrocytes may also be highly relevant in inducing astrocyte-microglia cell interactions through cytokine/mediator release leading to microglial activation...
Selective impairment of corticotropin-releasing factor1 (CRF1) receptor-mediated function using CRF coupled to saporin
D Maciejewski-Lenoir
Neurocrine Biosciences, Inc, San Diego, California 92121, USA
Endocrinology 141:498-504. 2000
..Taken together, these results suggest the utility of CRF-SAP as a specific and subtype-selective tool for long term impairment of CRF1 receptor-expressing cells...
The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia
S A Boehme
Neurocrine Biosciences, Inc, San Diego, CA 92121, USA
J Immunol 165:397-403. 2000
..These results, therefore, suggest that the interaction between fractalkine and CX3CR-1 may play an important role in promoting and preserving microglial cell survival in the CNS...