M E Hoffer

Summary

Affiliation: Naval Medical Center
Country: USA

Publications

  1. ncbi request reprint Posttraumatic balance disorders
    Michael E Hoffer
    Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 13:69-72. 2007
  2. ncbi request reprint Vestibular testing abnormalities in individuals with motion sickness
    Michael E Hoffer
    Department of Defense, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Otol Neurotol 24:633-6. 2003
  3. ncbi request reprint Characterizing and treating dizziness after mild head trauma
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Otol Neurotol 25:135-8. 2004
  4. ncbi request reprint Transtympanic management of tinnitus
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Otolaryngol Clin North Am 36:353-8. 2003
  5. ncbi request reprint Use of the round window microcatheter in the treatment of Meniere's disease
    M E Hoffer
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Laryngoscope 111:2046-9. 2001
  6. ncbi request reprint Microdose gentamicin administration via the round window microcatheter: results in patients with Meniere's disease
    M E Hoffer
    The Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, California 93124 2200, USA
    Ann N Y Acad Sci 942:46-51. 2001
  7. ncbi request reprint Sustained-release delivery of leupeptin in the chinchilla: hearing results
    Michael E Hoffer
    Department of Defense, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 9:76-8. 2003
  8. ncbi request reprint Sustained-release devices in inner ear medical therapy
    Michael E Hoffer
    The Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 93134, USA
    Otolaryngol Clin North Am 37:1053-60. 2004
  9. ncbi request reprint Delivery of drugs to the inner ear
    Michael E Hoffer
    Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Curr Opin Otolaryngol Head Neck Surg 14:329-31. 2006
  10. ncbi request reprint The early kinetics of gentamicin uptake into the inner ear
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 8:27-9. 2002

Detail Information

Publications22

  1. ncbi request reprint Posttraumatic balance disorders
    Michael E Hoffer
    Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 13:69-72. 2007
    ..As dizziness is one of the most common outcomes of TBI, it is essential that those who study and treat dizziness be familiar with this subject...
  2. ncbi request reprint Vestibular testing abnormalities in individuals with motion sickness
    Michael E Hoffer
    Department of Defense, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Otol Neurotol 24:633-6. 2003
    ..The goal of this study was to compare the results of vestibular testing in individuals with motion sickness to a group of control subjects...
  3. ncbi request reprint Characterizing and treating dizziness after mild head trauma
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Otol Neurotol 25:135-8. 2004
    ..The objectives of this study were to characterize patterns of dizziness seen after mild head trauma and to examine the diagnosis and treatment of this disorder...
  4. ncbi request reprint Transtympanic management of tinnitus
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Otolaryngol Clin North Am 36:353-8. 2003
    ..Ideally in the future with knowledge of the disease and its etiology the physician will simply pick the established medicine, the established dose, and the established route of administration and achieve a relatively predictable result...
  5. ncbi request reprint Use of the round window microcatheter in the treatment of Meniere's disease
    M E Hoffer
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Laryngoscope 111:2046-9. 2001
    ..We applied the 1995 American Academy of Otolaryngology-Head and Neck Surgery criteria to this patient group to analyze the results of treatment...
  6. ncbi request reprint Microdose gentamicin administration via the round window microcatheter: results in patients with Meniere's disease
    M E Hoffer
    The Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, California 93124 2200, USA
    Ann N Y Acad Sci 942:46-51. 2001
    ..Our results are compared to the published literature examining transtympanic injection. In addition, the underlying science supporting this type of treatment is examined...
  7. ncbi request reprint Sustained-release delivery of leupeptin in the chinchilla: hearing results
    Michael E Hoffer
    Department of Defense, Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 9:76-8. 2003
    ..The medicine produced no hearing loss at the early time points but did produce some hearing loss at later time points. We discuss these results and begin to outline the next steps in the investigation of this agent...
  8. ncbi request reprint Sustained-release devices in inner ear medical therapy
    Michael E Hoffer
    The Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 93134, USA
    Otolaryngol Clin North Am 37:1053-60. 2004
    ..This article discusses the results of this work and the application and use of sustained-release devices in patients...
  9. ncbi request reprint Delivery of drugs to the inner ear
    Michael E Hoffer
    Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, California 92134 2200, USA
    Curr Opin Otolaryngol Head Neck Surg 14:329-31. 2006
    ..The purpose of this review is to examine the literature that has been published recently (since January of 2005) in this field and to explore how this new literature has impacted on current practices...
  10. ncbi request reprint The early kinetics of gentamicin uptake into the inner ear
    Michael E Hoffer
    Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Int Tinnitus J 8:27-9. 2002
    ..The information gained from this study may increase our scientific understanding about the effects of gentamicin on the inner ear and may allow clinicians to treat patients more effectively for inner-ear disorders...
  11. ncbi request reprint Transtympanic versus sustained-release administration of gentamicin: kinetics, morphology, and function
    M E Hoffer
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, San Diego, CA 92134-2200
    Laryngoscope 111:1343-57. 2001
    ..Sustained delivery of gentamicin produces universal HL at 72 hours. The reliability of sustained-release delivery to the ear reduces functional and morphological variations between animals...
  12. ncbi request reprint Morphologic changes in the inner ear of Chinchilla laniger after middle ear administration of gentamicin in a sustained-release vehicle
    M E Hoffer
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, CA 92134 5000, USA
    Otolaryngol Head Neck Surg 120:643-8. 1999
    ..We also examine measurement of hair cell damage with heat shock protein levels. By better understanding the actions of gentamicin in this animal model, we hope to facilitate safer use of intratympanic medicines in our patient population...
  13. ncbi request reprint Reduction of noise-induced hearing loss using L-NAC and salicylate in the chinchilla
    R D Kopke
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Hear Res 149:138-46. 2000
    ..These findings demonstrate the feasibility of reduction of noise-induced hearing loss using clinically available antioxidant compounds...
  14. ncbi request reprint Targeted topical steroid therapy in sudden sensorineural hearing loss
    R D Kopke
    The Department of Defense Spatial Orientation Center, Naval Medical Center, San Diego, California 92134-2200, USA
    Otol Neurotol 22:475-9. 2001
    ....
  15. pmc Growth factor treatment enhances vestibular hair cell renewal and results in improved vestibular function
    R D Kopke
    Departments of Defense Spatial Orientation Center and Otolaryngology, Naval Medical Center, San Diego, CA 92134, USA
    Proc Natl Acad Sci U S A 98:5886-91. 2001
    ..These results suggest that growth factor therapy may be an effective treatment for balance disorders that are the result of hair cell dysfunction and/or loss...
  16. ncbi request reprint Objective vestibular tests as outcome measures in head injury patients
    Kim Gottshall
    Vestibular Assessment and Rehabilitation, Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 2200, USA
    Laryngoscope 113:1746-50. 2003
    ..Dynamic visual acuity testing (DVAT) and the Dizziness Handicap Index (DHI) can be used as reliable outcome measures in patients after head injury...
  17. ncbi request reprint Distribution of PLGA nanoparticles in chinchilla cochleae
    Xianxi Ge
    Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA 92134 5000, USA
    Otolaryngol Head Neck Surg 137:619-23. 2007
    ..To study the distribution of polylactic/glycolic acid-encapsulated iron oxide nanoparticles (PLGA-NPs) in chinchilla cochleae after application on the round window membrane (RWM)...
  18. ncbi request reprint Active head movements facilitate compensation for effects of prism displacement on dynamic gait
    Kim R Gottshall
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, CA 92134, USA
    J Vestib Res 16:29-33. 2006
    ..Four groups, between-subjects study...
  19. ncbi request reprint Vestibular rehabilitation for migraine-associated dizziness
    Kim R Gottshall
    Department of Defense Spatial Orientation Center, Naval Medical Center, San Diego, CA 92134, USA
    Int Tinnitus J 11:81-4. 2005
    ..Patients with migraine-associated dizziness can benefit from physical therapy intervention. The results of this study are important in considering the approach to vertiginous migraine patients with and without head injury...
  20. ncbi request reprint The role of vestibular rehabilitation in the treatment of Meniere's disease
    Kim R Gottshall
    Department of Defense Spatial Orientation Center, Naval Medical Center San Diego, CA 92134, USA
    Otolaryngol Head Neck Surg 133:326-8. 2005
    ..To study the role of vestibular rehabilitation is treating patients with Meniere's disease...
  21. ncbi request reprint U.S. Phase I preliminary results of use of the Otologics MET Fully-Implantable Ossicular Stimulator
    Herman A Jenkins
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Otolaryngol Head Neck Surg 137:206-12. 2007
    ..The safety of the Otologics Fully-Implantable MET Ossicular Stimulator was assessed in adult patients with bilateral moderate to severe sensorineural hearing loss...
  22. doi request reprint Otologics fully implantable hearing system: Phase I trial 1-year results
    Herman A Jenkins
    University of Colorado Denver, Aurora, Colorado 80045, USA
    Otol Neurotol 29:534-41. 2008
    ..To assess the safety of the Otologics fully implantable hearing system after 1 year of use in a Phase I clinical trial...