C G Hayes

Summary

Affiliation: Naval Medical Center
Country: USA

Publications

  1. ncbi request reprint West Nile virus: Uganda, 1937, to New York City, 1999
    C G Hayes
    Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    Ann N Y Acad Sci 951:25-37. 2001
  2. ncbi request reprint Characterization of antibody responses to combinations of a dengue-2 DNA and dengue-2 recombinant subunit vaccine
    M Simmons
    Virology Program, Naval Medical Research Center, Silver Spring, Maryland 20910-7500, USA
    Am J Trop Med Hyg 65:420-6. 2001
  3. pmc Development and evaluation of serotype- and group-specific fluorogenic reverse transcriptase PCR (TaqMan) assays for dengue virus
    J D Callahan
    Viral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910-7500, USA
    J Clin Microbiol 39:4119-24. 2001
  4. ncbi request reprint Hepatitis E virus DNA vaccine elicits immunologic memory in mice
    J He
    Department of Virus Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Silver Spring, MD 20910, USA
    J Biomed Sci 8:223-6. 2001
  5. ncbi request reprint A dengue virus serotype-1 DNA vaccine induces virus neutralizing antibodies and provides protection from viral challenge in Aotus monkeys
    T J Kochel
    Virology Program, Naval Medical Research Center, 8901 Wisconsin Avenue, 20889 5607, Bethesda, MD, USA
    Vaccine 18:3166-73. 2000
  6. pmc Evaluation of a dipstick enzyme-linked immunosorbent assay for detection of antibodies to dengue virus
    S J Wu
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889 5607, USA
    Clin Diagn Lab Immunol 4:452-7. 1997
  7. ncbi request reprint Short report: Antibody responses of mice immunized with a tetravalent dengue recombinant protein subunit vaccine
    M Simmons
    Virology Program, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    Am J Trop Med Hyg 65:159-61. 2001
  8. pmc Detection of dengue viral RNA using a nucleic acid sequence-based amplification assay
    S J Wu
    Viral Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    J Clin Microbiol 39:2794-8. 2001
  9. ncbi request reprint Synergistic neutralizing antibody response to a dengue virus type 2 DNA vaccine by incorporation of lysosome-associated membrane protein sequences and use of plasmid expressing GM-CSF
    K Raviprakash
    Virology Program, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, Maryland 20910, USA
    Virology 290:74-82. 2001
  10. ncbi request reprint Dengue virus type 1 DNA vaccine induces protective immune responses in rhesus macaques
    K Raviprakash
    Virology Program, Infectious Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Rm 3N71, Silver Spring, MD 20910 7500, USA
    J Gen Virol 81:1659-67. 2000

Collaborators

Detail Information

Publications18

  1. ncbi request reprint West Nile virus: Uganda, 1937, to New York City, 1999
    C G Hayes
    Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    Ann N Y Acad Sci 951:25-37. 2001
    ..This review will attempt to compare observations on the biology of West Nile virus made over about 60 years prior to the recent epidemics to observations made in association with these urban epidemics...
  2. ncbi request reprint Characterization of antibody responses to combinations of a dengue-2 DNA and dengue-2 recombinant subunit vaccine
    M Simmons
    Virology Program, Naval Medical Research Center, Silver Spring, Maryland 20910-7500, USA
    Am J Trop Med Hyg 65:420-6. 2001
    ..Our observations indicate that the combination RD prime-boost regimen warrants further investigation as a vaccine strategy to prevent dengue infection...
  3. pmc Development and evaluation of serotype- and group-specific fluorogenic reverse transcriptase PCR (TaqMan) assays for dengue virus
    J D Callahan
    Viral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910-7500, USA
    J Clin Microbiol 39:4119-24. 2001
    ..Our results demonstrate that the dengue virus TaqMan RT-PCR assays may be utilized as rapid, sensitive, and specific screening and serotyping tools for epidemiological studies of dengue virus infections...
  4. ncbi request reprint Hepatitis E virus DNA vaccine elicits immunologic memory in mice
    J He
    Department of Virus Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Silver Spring, MD 20910, USA
    J Biomed Sci 8:223-6. 2001
    ..We speculate that this type of response could protect a human from overt disease...
  5. ncbi request reprint A dengue virus serotype-1 DNA vaccine induces virus neutralizing antibodies and provides protection from viral challenge in Aotus monkeys
    T J Kochel
    Virology Program, Naval Medical Research Center, 8901 Wisconsin Avenue, 20889 5607, Bethesda, MD, USA
    Vaccine 18:3166-73. 2000
    ..These results demonstrate that DNA immunization is a promising approach for the development of dengue vaccines and that A. nancymae monkeys are suitable for dengue vaccine trials...
  6. pmc Evaluation of a dipstick enzyme-linked immunosorbent assay for detection of antibodies to dengue virus
    S J Wu
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889 5607, USA
    Clin Diagn Lab Immunol 4:452-7. 1997
    ..The dipstick ELISA was also shown to be useful for detecting seroconversions to DEN IgM or IgG in paired serum samples from 20 patients with virus isolation-confirmed acute DEN infections...
  7. ncbi request reprint Short report: Antibody responses of mice immunized with a tetravalent dengue recombinant protein subunit vaccine
    M Simmons
    Virology Program, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    Am J Trop Med Hyg 65:159-61. 2001
    ....
  8. pmc Detection of dengue viral RNA using a nucleic acid sequence-based amplification assay
    S J Wu
    Viral Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910 7500, USA
    J Clin Microbiol 39:2794-8. 2001
    ..The NASBA assay had a specificity of 100% based on the negative test results for the 21 normal human serum or plasma samples. These results indicate that the NASBA assay is a promising assay for the early diagnosis of dengue infections...
  9. ncbi request reprint Synergistic neutralizing antibody response to a dengue virus type 2 DNA vaccine by incorporation of lysosome-associated membrane protein sequences and use of plasmid expressing GM-CSF
    K Raviprakash
    Virology Program, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, Maryland 20910, USA
    Virology 290:74-82. 2001
    ..The highest antibody responses were noted when the modified construct was coinjected with plasmid expressing the GM-CSF gene. These results could form the basis for an effective tetravalent dengue virus DNA vaccine...
  10. ncbi request reprint Dengue virus type 1 DNA vaccine induces protective immune responses in rhesus macaques
    K Raviprakash
    Virology Program, Infectious Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Rm 3N71, Silver Spring, MD 20910 7500, USA
    J Gen Virol 81:1659-67. 2000
    ..Vaccine-induced antibody had an avidity index similar to that of antibody induced by virus infection; however, no clear correlation was apparent between antibody avidity and virus neutralization titres...
  11. ncbi request reprint Construction of a full length infectious clone for dengue-1 virus Western Pacific,74 strain
    B Puri
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, MD 20889 5607, USA
    Virus Genes 20:57-63. 2000
    ..Biological properties of the transcript-derived virus, such as the pattern of dengue-specific protein synthesis and growth rate in LLCMK2 or C6/36 cells, resembled those of the parent DEN1 WP virus...
  12. ncbi request reprint Immunogenicity of dengue virus type 1 DNA vaccines expressing truncated and full length envelope protein
    K Raviprakash
    Virology Program, Infectious Diseases Department, Naval Medical Research Institute, 8901 Wisconsin Avenue, Bethesda, MD, USA
    Vaccine 18:2426-34. 2000
    ..Data suggested that the plasmid expressing prM and full length E produced virus like particles in transfected cells, and is probably a better immunogen compared to that expressing 80% E...
  13. pmc Comparison of two rapid diagnostic assays for detection of immunoglobulin M antibodies to dengue virus
    S J Wu
    Viral and Rickettsial Diseases Department, Naval Medical Research Center, Bethesda, Maryland 20889 5607, USA
    Clin Diagn Lab Immunol 7:106-10. 2000
    ..3 and 97.1%, respectively. Both commercial assays provide sensitive and specific detection of anti-dengue virus IgM antibody and could prove useful in settings where the microplate ELISA is impractical...
  14. ncbi request reprint Complete nucleotide sequence analysis of a Western Pacific dengue-1 virus strain
    B Puri
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889 5607, USA
    Virus Genes 17:85-8. 1998
    ..When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively...
  15. ncbi request reprint Molecular analysis of dengue virus attenuation after serial passage in primary dog kidney cells
    B Puri
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889 5607, USA
    J Gen Virol 78:2287-91. 1997
    ..Important nucleotide base changes responsible for attenuation accumulated between 45AZ5 PDK-O and 27...
  16. ncbi request reprint Molecular characterization of a hepatitis E virus isolate from Namibia
    J He
    Department of Virus Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Silver Spring, MD 20910, USA
    J Biomed Sci 7:334-8. 2000
    ..These data link the HEV causing the 1983 Namibia outbreak to more recent HEV transmission in northern and sub-Saharan Africa, suggesting this subgenotype of HEV is firmly established throughout the continent...
  17. ncbi request reprint Haiti: absence of dengue hemorrhagic fever despite hyperendemic dengue virus transmission
    S B Halstead
    Medical Science and Technology Division, Office of Naval Research, Arlington, Virginia 22217-5660, USA
    Am J Trop Med Hyg 65:180-3. 2001
    ..These observations, which are reminiscent of those in Africa, provide further evidence of a dengue resistance gene in black populations...
  18. ncbi request reprint Conversion of dengue virus replicative form RNA (RF) to replicative intermediate (RI) by nonstructural proteins NS-5 and NS-3
    K Raviprakash
    Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889, USA
    Am J Trop Med Hyg 58:90-5. 1998
    ..The recombinant proteins, however, required one or more cellular protein(s) for their activity. Examination of NS-3 protein sequence revealed heretofore unnoticed sequence similarities with other polymerases...