Research Topics
| C L AmlingSummaryAffiliation: Naval Medical Center Country: USA Publications
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Detail Information
Publications
Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomyChristopher L Amling
Department of Urology, Naval Medical Center, 34800 Bob Wilson Drive, San Diego, CA 92134 5000, USA
J Clin Oncol 22:439-45. 2004....
Relationship between obesity and prostate cancerChristopher L Amling
Department of Urology, Naval Medical Center, San Diego, California 92134 5000, USA
Curr Opin Urol 15:167-71. 2005..This review examines the relationship between obesity and prostate cancer, with an update of recent research in this field...
Biochemical failure: role for early hormonal therapyC L Amling
Naval Medical Center, San Diego, California, USA
BJU Int 94:9-10. 2004
Advanced prostate cancer treatment guidelines: a United States perspectiveC L Amling
Naval Medical Center, San Diego, California, USA
BJU Int 94:7-8. 2004
Impact of nerve sparing on surgical margins and biochemical recurrence: results from the SEARCH databaseJ L Nelles
Department of Urology, San Francisco School of Medicine, University of California, San Francisco, CA, USA
Prostate Cancer Prostatic Dis 12:172-6. 2009..The risk for biochemical recurrence was not affected by bilateral or unilateral nerve sparing. When used on appropriately selected patients, nerve sparing does not increase the probability of PSM or biochemical recurrence after RP...
Relationship between obesity and race in predicting adverse pathologic variables in patients undergoing radical prostatectomyC L Amling
Department of Urology, Naval Medical Center, San Diego, California, USA
Urology 58:723-8. 2001..Blacks have higher grade cancers than other ethnic groups and, at the same time, have significantly higher BMIs. These findings suggest that obesity may in part account for the racial variability in PCa risk...
Impact of obesity on biochemical control after radical prostatectomy for clinically localized prostate cancer: a report by the Shared Equal Access Regional Cancer Hospital database study groupStephen J Freedland
Department of Urology, The Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287 2101, USA
J Clin Oncol 22:446-53. 2004..Given the limited information regarding the impact of obesity on treatment outcomes for prostate cancer, we sought to examine the relationship between body mass index (BMI) and cancer control after radical prostatectomy (RP)...
Do younger men have better biochemical outcomes after radical prostatectomy?Stephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Urology 63:518-22. 2004..Prior studies have suggested that younger men have lower prostate-specific antigen recurrence rates after RP, although none of the prior studies had controlled for the year of surgery...
Improved clinical staging system combining biopsy laterality and TNM stage for men with T1c and T2 prostate cancer: results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California-Los Angeles School of Medicine and Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90095, USA
J Urol 169:2129-35. 2003..If confirmed at other centers and in men who undergo with other treatment modalities, consideration should be given to revising the current TNM staging system to reflect these findings...
Race as an outcome predictor after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90095-1738, USA
Urology 60:670-4. 2002..The Shared Equal Access Regional Cancer Hospital database is a valuable resource for studying patients treated with RP...
Efficacy of digital rectal examination after radiotherapy for prostate cancerP A Johnstone
Radiation Oncology Division and Clinical Investigation Department, Naval Medical Center, University of California, San Diego, California 92134-1014, USA
J Urol 166:1684-7. 2001..CONCLUSIONS: Routine digital rectal examination in patients with prostate cancer after radiotherapy may be omitted from followup protocols...
Malignant cytological washings from prostate specimens: an independent predictor of biochemical progression after radical prostatectomyJ F Ward
Departments of Urology and Pathology, Naval Medical Center, San Diego, California, USA
J Urol 165:469-73. 2001..One month of total androgen blockade preoperatively significantly decreases the rate of positive cytology but does not appear to change the rate of early biochemical failure...
Repeat biopsy strategy in patients with atypical small acinar proliferation or high grade prostatic intraepithelial neoplasia on initial prostate needle biopsyP G Borboroglu
Department of Urology, Naval Medical Center-San Diego, 34800 Bob Wilson Drive, Suite 5, San Diego, CA 92134-1005, USA
J Urol 166:866-70. 2001..The optimal repeat biopsy strategy in this setting should include bilateral biopsies of the standard sextant locations. We also strongly recommend that transition zone sampling should be considered...
Correlation of positive prostate sextant biopsy locations to sites of positive surgical margins in radical prostatectomy specimensP G Borboroglu
Department of Urology, Naval Medical Center San Diego, San Diego, CA 92134-1005, USA
Eur Urol 39:648-53; discussion 654. 2001..While pathologic processing of biopsy specimens according to longitudinal prostate location (base, mid and apex) is probably unnecessary, the number of positive biopsies on a given side may be useful preoperative information...
Obesity and biochemical outcome following radical prostatectomy for organ confined disease with negative surgical marginsStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287 2101, USA
J Urol 172:520-4. 2004....
Outcomes after radical prostatectomy among men who are candidates for active surveillance: results from the SEARCH databaseChristopher J Kane
Division of Urology, Department of Surgery, University of California San Diego, San Diego, CA 92103 8897, USA
Urology 76:695-700. 2010..We sought to evaluate outcomes after radical prostatectomy among men with low-risk prostate cancer who would be candidates for active surveillance...
The percentage of prostate needle biopsy cores with carcinoma from the more involved side of the biopsy as a predictor of prostate specific antigen recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARStephen J Freedland
Department of Urology, University of California-Los Angeles, Los Angeles, California, USA
Cancer 98:2344-50. 2003..Using the percentage of cores from the dominant side along with the PSA level and the biopsy Gleason score provided significant risk stratification for PSA failure...
Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3? Results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California Los Angeles and Department of Surgery, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, California 90095, USA
J Urol 169:2142-6. 2003..We examined the significance of the pathological features of positive surgical margin and extracapsular extension for predicting biochemical failure following radical prostatectomy...
Biochemical outcome after radical prostatectomy among men with normal preoperative serum prostate-specific antigen levelsStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Cancer 101:748-53. 2004..Whether malignancies in such men are associated with better outcomes is unclear. The authors compared the risk of biochemical failure after radical prostatectomy (RP) between men with normal PSA levels and men with elevated PSA levels...
Time trends in biochemical recurrence after radical prostatectomy: results of the SEARCH databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, 90095-1738, USA
Urology 61:736-41. 2003..This may reflect lead-time bias in detecting PSA recurrence by the use of more sensitive PSA assays in recent years...
Freedom from a detectable ultrasensitive prostate-specific antigen at two years after radical prostatectomy predicts a favorable clinical outcome: analysis of the SEARCH databaseSteven L Chang
Department of Urology, Stanford University Medical Center, Stanford, California 94305, USA
Urology 75:439-44. 2010..Previous studies demonstrate that a PSADT < 9 months after radical prostatectomy is associated with prostate cancer-specific mortality. Conventionally, PSADT has been calculated after biochemical failure (PSA > or = 2 0.2 ng/mL)...
Initiation of salvage therapy for prostate cancerP A S Johnstone
Radiation Oncology Division, Naval Medical Center San Diego, California 92134 1005, USA
Prostate Cancer Prostatic Dis 5:136-43. 2002..These are strikingly interdependent, and few clear absolutes are evident from this questionnaire. This is a point of necessary further research and continued discussion among physicians caring for these patients...
Transureteral saline perfusion to obtain renal hypothermia: potential application in laparoscopic partial nephrectomyDonald S Crain
Department of Urology, Naval Medical Center San Diego, 34800 Bob Wilson Dr, San Diego, CA 92134 5000, USA
JSLS 8:217-22. 2004..Laparoscopic surgery precludes traditional ice-slush cooling. To facilitate renal cooling during laparoscopic partial nephrectomy, we investigated a method of intrarenal cooling by retrograde transureteral iced saline perfusion...
Multiinstitutional validation of the UCSF cancer of the prostate risk assessment for prediction of recurrence after radical prostatectomyMatthew R Cooperberg
Department of Urology, Program in Urologic Oncology, Urologic Outcomes Research Group, UCSF Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
Cancer 107:2384-91. 2006..This study used a large external dataset to validate CAPRA...
Prostate carcinoma among men with human immunodeficiency virus infectionNancy F Crum
Division of Infectious Diseases, Department of Internal Medicine, Naval Medical Center San Diego, San Diego, California 92134, USA
Cancer 101:294-9. 2004..To determine the incidence of prostate carcinoma in men with HIV infection, the authors initiated a prostate carcinoma screening program in a large HIV clinic...
Preoperative model for predicting prostate specific antigen recurrence after radical prostatectomy using percent of biopsy tissue with cancer, biopsy Gleason grade and serum prostate specific antigenStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Urol 171:2215-20. 2004..We developed a preoperative model to risk stratify patients for prostate specific antigen (PSA) failure following radical prostatectomy (RP) and identify those at high risk who would be potential candidates for neoadjuvant clinical trials...
Predictors of prostate-specific antigen progression among men with seminal vesicle invasion at the time of radical prostatectomyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Cancer 100:1633-8. 2004..The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival...
Effect of race on biochemical disease-free outcome in patients with prostate cancer treated with definitive radiation therapy in an equal-access health care system: radiation oncology report of the Department of Defense Center for Prostate Disease ResearcPeter A S Johnstone
Naval Medical Ctr, San Diego, Calif 92134 1014, USA
Radiology 225:420-6. 2002..To report on the first collaboration of the Department of Defense Center for Prostate Disease Research concerned with the relationship between African American race and biochemical disease-free outcomes after definitive radiation therapy...
Comparison of percentage of total prostate needle biopsy tissue with cancer to percentage of cores with cancer for predicting PSA recurrence after radical prostatectomy: results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, 90095-1738, USA
Urology 61:742-7. 2003....
Comparison of preoperative prostate specific antigen density and prostate specific antigen for predicting recurrence after radical prostatectomy: results from the search data baseStephen J Freedland
Department of Urology, University of California-Los Angeles School of Medicine, USA
J Urol 169:969-73. 2003..The minimal and statistically insignificant improvement in preoperative risk assessment provided by PSA density does not justify the time and effort necessary to calculate this value...
A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: diagnosis, pathogenesis, and managementNancy F Crum
Infectious Diseases Division, Naval Medical Center San Diego, San Diego, California 92134 1005, USA
AIDS Patient Care STDS 19:655-71. 2005..We review the epidemiology, diagnosis, pathogenesis, and treatment options of both hypogonadism and ED among HIV-infected men...
Percent of prostate needle biopsy cores with cancer is significant independent predictor of prostate specific antigen recurrence following radical prostatectomy: results from SEARCH databaseStephen J Freedland
Department of Urology, University of California Los Angeles, Department of Surgery, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, California 90095, USA
J Urol 169:2136-41. 2003....
Effect of age on biochemical disease-free outcome in patients with T1-T3 prostate cancer treated with definitive radiotherapy in an equal-access health care system: a radiation oncology report of the Department of Defense Center for Prostate Disease ReseaPeter A S Johnstone
Investigation Department, Naval Medical Center, San Diego, CA 92134, USA
Int J Radiat Oncol Biol Phys 55:964-9. 2003..The records of the Department of Defense Center for Prostate Disease Research were queried for the biochemical disease-free results of patients after definitive RT and analyzed by age...
Practice patterns in vasectomy reversal surgery: results of a questionnaire study among practicing urologistsDonald S Crain
Urology Department, Naval Medical Center San Diego, 92134 5000, USA
J Urol 171:311-5. 2004..We designed a questionnaire to assess the practice patterns of community and academic urologists with respect to surgical technique, followup care, patient selection and the definition of success...
Profound anemia from duodenal invasion of metastatic testicular seminomaHernan O Altamar
Department of Urology, Naval Medical Center San Diego, California 92134-1005, USA
J Urol 171:344-5. 2004
Defining prostate specific antigen progression after radical prostatectomy: what is the most appropriate cut point?C L Amling
Department of Urology, Naval Medical Center, San Diego, California, USA
J Urol 165:1146-51. 2001..Aspects of the American Society for Therapeutic Radiology and Oncology (ASTRO) definition of biochemical failure after radiation therapy are also analyzed in our radical prostatectomy cases...
Is there a difference in outcome after radical prostatectomy between patients with biopsy Gleason sums 4, 5, and 6? Results from the SEARCH databaseS J Freedland
Department of Urology, UCLA School of Medicine, Los Angeles, California 90095 1738, USA
Prostate Cancer Prostatic Dis 6:261-5. 2003..We sought to examine the significance of biopsy Gleason sum for predicting biochemical failure following radical prostatectomy (RP) for men with biopsy Gleason sums of 4, 5, and 6...
Intraoperative cell salvage in radical retropubic prostatectomyC L Gray
Department ofUrology, Naval Medical Center, San Diego, California, USA
Urology 58:740-5. 2001..Cell salvage does not appear to be associated with an increased risk of early biochemical progression after RRP...
Ureteral stenting after ureteroscopy for distal ureteral calculi: a multi-institutional prospective randomized controlled study assessing pain, outcomes and complicationsP G Borboroglu
Department of Urology, Naval Medical Center and Division of Urology, University of California, San Diego, California 92134-1005, USA
J Urol 166:1651-7. 2001..Patients without stents had significantly less pain, fewer urinary symptoms and decreased narcotic use postoperatively...
Outcomes for surgical management of orchalgia in patients with identifiable intrascrotal lesionsC L Gray
Department of Urology, Naval Medical Center, San Diego, Calif 92134 5000, USA
Eur Urol 39:455-9. 2001..We evaluated the success of commonly performed surgical procedure indicated for pain relief in patients with specific intrascrotal lesions...
Prostate size and risk of high-grade, advanced prostate cancer and biochemical progression after radical prostatectomy: a search database studyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287 2101, USA
J Clin Oncol 23:7546-54. 2005..We examined whether prostate weight was associated with tumor grade, advanced disease, or risk of biochemical progression after radical prostatectomy (RP)...
Racial differences in prognostic value of adult height for biochemical progression following radical prostatectomyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin Cancer Res 11:7735-42. 2005..However, hormonal activity and diets vary between races. We examined whether height was significantly associated with biochemical progression following radical prostatectomy and whether there was an interaction between height and race...
Diagnosis and management of superficial bladder cancerC L Amling
Department of Urology, Naval Medical Center, San Diego, California, USA
Curr Probl Cancer 25:219-78. 2001..With the development of orthotopic lower urinary tract reconstruction to the native urethra, the quality of life impact of radical cystectomy has been lessened...
Prostate cancer mortality rates compared to urologist population densities and prostate-specific antigen screening levels on a state-by-state basis in the United States of AmericaJ L Colli
Department of Urology, University of Alabama, Birmingham, AL 35294, USA
Prostate Cancer Prostatic Dis 11:247-51. 2008..We found that prostate cancer mortality rates correlated inversely with urologist population densities (P<0.01) and PSA screening (P<0.01) suggesting that screening and treatment reduce prostate cancer mortality...
A prospective randomized comparison of extensive prostate biopsy to standard biopsy with assessment of diagnostic yield, biopsy pain and morbidityR L Sur
Department of Urology, Naval Medical Center, San Diego, California 92134-5000, USA
Prostate Cancer Prostatic Dis 7:126-31. 2004..Extended biopsy with 24 samples does not improve cancer detection compared to standard biopsy when 10 cores are obtained. Extensive biopsy is very well tolerated and associated with less pain and more satisfaction than standard biopsy...
Delay of radical prostatectomy and risk of biochemical progression in men with low risk prostate cancerStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Urol 175:1298-302; discussion 1302-3. 2006..Whether delays and especially prolonged delays, eg greater than 180 days, before RP negatively impact the disease outcome is unclear...
Exploring causes for declining prostate cancer mortality rates in the United StatesJanet L Colli
Department of Urology, University of Alabama, Birmingham, AL 35294, USA Birmingham VA Medical Center VMAC, Birmingham, AL 35294, USA
Urol Oncol 26:627-33. 2008..The purpose of this study is to compare declining prostate cancer mortality rates among states with independent variables that may have an association to explore causes for the decline...
Obesity, serum prostate specific antigen and prostate size: implications for prostate cancer detectionStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Urol 175:500-4; discussion 504. 2006..We examined the association between BMI, and PSA and prostate weight in a cohort of men undergoing RP...
Limited value of bone scintigraphy and computed tomography in assessing biochemical failure after radical prostatectomyChristopher J Kane
Department of Urology, Naval Medical Center San Diego, San Diego, California, USA
Urology 61:607-11. 2003..4%) or a positive CT scan (14.0%) within 3 years of biochemical recurrence. Most patients with a positive bone scan have a high PSA level and a high PSA velocity (greater than 0.5 ng/mL/mo)...
The association between obesity and the progression of prostate and renal cell carcinomaChristopher L Amling
Department of Urology, Naval Medical Center, 34800 Bob Wilson Drive, San Diego, CA 92134 5000, USA
Urol Oncol 22:478-84. 2004..Since obesity is one of few modifiable risk factors that may impact the clinical course of these cancers, lifestyle and dietary changes to limit obesity should be recommended...
Use of early PSA velocity to predict eventual abnormal PSA values in men at risk for prostate cancerR H Riffenburgh
Department of Clinical Investigation, Naval Medical Center, San Diego, California 92134 5000, USA
Prostate Cancer Prostatic Dis 6:39-44. 2003..Early PSAV from normal PSA readings may allow early detection of men at risk for prostate cancer. This may help identify men for earlier prostate biopsy or for less frequent PSA monitoring...
Prostate cancer in men using testosterone supplementationFranklin D Gaylis
Division of Urology, University of California at San Diego Medical Center, San Diego, California, USA
J Urol 174:534-8; discussion 538. 2005..To increase awareness of this risk, we report on a series of patients in whom clinically significant prostate cancer developed and was presumed to be related to exogenous testosterone use...
High cholesterol levels are associated with reduced prostate cancer mortality rates during periods of high but not low statin use in the United StatesJanet L Colli
Department of Urology, University of Alabama, Birmingham, AL 35294, USA
Urol Oncol 27:170-3. 2009..We hypothesize that prostate cancer risks from high cholesterol may be reduced when statin use is high...
Multilocular cystic renal cell carcinoma with osseous metaplasia in a 25-year-old womanTammy L Bloom
Department ofUrology, Naval Medical Center San Diego, San Diego, California 92134-5000, USA
Urology 61:462. 2003..We report a case of a markedly calcified multilocular renal cell carcinoma, clear cell type, with diffuse osseous metaplasia...
Renal cell carcinoma rates compared with health status and behavior in the United StatesJanet L Colli
Department of Urology, University of Alabama at Birmingham, 1530 3rd Avenue, South Birmingham, AL 35294, USA
Urology 73:431-6. 2009..To explore the relationship between renal cell carcinoma rates and health status and behavior in the United States...
A prospective, randomized pilot trial of acupuncture of the kidney-bladder distinct meridian for lower urinary tract symptomsPeter A Johnstone
Radiation Oncology Division and Urology Department, Naval Medical Center, San Diego, California, USA
J Urol 169:1037-9. 2003..945 for PSA and p = 0.37 for the free-to-total PSA ratio. CONCLUSIONS: Acupuncture to the kidney-bladder distinct meridian neither relieves lower urinary tract symptoms nor impacts PSA...
Palliative transurethral prostate resection for bladder outlet obstruction in patients with locally advanced prostate cancerDonald S Crain
Department of Urology, Naval Medical Center San Diego, California 92134, USA
J Urol 171:668-71. 2004..However, the rates of postoperative urinary retention and reoperation are higher than in patients undergoing TURP for BPH...
Obesity-related plasma hemodilution and PSA concentration among men with prostate cancerLionel L Banez
Division of Urologic Surgery and the Duke Prostate Center, and Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
JAMA 298:2275-80. 2007..Because men with higher body mass index (BMI) have greater circulating plasma volumes, lower PSA concentrations among obese men may be due to hemodilution...
Small transrectal ultrasound volume predicts clinically significant Gleason score upgrading after radical prostatectomy: results from the SEARCH databaseRyan S Turley
Division of Urological Surgery, Duke Prostate Center, Duke University School of Medicine, Durham, North Carolina, USA
J Urol 179:523-7; discussion 527-8. 2008..We examined the likelihood of clinically relevant upgrading after radical prostatectomy as a function of transrectal ultrasound volume...
The effect of race/ethnicity on the accuracy of the 2001 Partin Tables for predicting pathologic stage of localized prostate cancerElisabeth I Heath
Barbara Ann Karmanos Cancer Institute, Department of Hematology and Oncology, Wayne State University, 4100 John R, 4 HWCRC, Detroit, MI 48201, USA
Urology 71:151-5. 2008..To test the accuracy of the 2001 Partin Tables in African American men who underwent radical prostatectomy at multiple centers throughout the United States...
Obesity and oncological outcome after radical prostatectomy: impact of prostate-specific antigen-based prostate cancer screening: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databasesStephen J Freedland
Urology Section, Department of Surgery, Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27710, USA
BJU Int 102:969-74. 2008....
Risk stratification for biochemical recurrence in men with positive surgical margins or extracapsular disease after radical prostatectomy: results from the SEARCH databaseJayakrishnan Jayachandran
Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
J Urol 179:1791-6; discussion 1796. 2008..We further stratified these men into a low risk group in which watchful waiting after surgery may be preferred and a high risk cohort in which adjuvant therapy may be preferred...
Limitations of prostate specific antigen doubling time following biochemical recurrence after radical prostatectomy: results from the SEARCH databaseRobert J Hamilton
Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
J Urol 179:1785-9; discussion 1789-90. 2008..Hence, those with calculable prostate specific antigen doubling time may represent a select lower risk group relative to all men with biochemical recurrence...
What are the factors associated with short prostate specific antigen doubling time after radical prostatectomy? A report from the SEARCH database groupAnna E Teeter
Division of Urologic Surgery and Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
J Urol 180:1980-4; discussion 1985. 2008..We determined which demographic and clinicopathological variables were predictive of a short prostate specific antigen doubling time in a cohort of men with clinically localized prostate cancer treated with radical prostatectomy...
Obesity and positive surgical margins by anatomic location after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital databaseJayakrishnan Jayachandran
Urology Section, Veterans Affairs Medical Center, Duke University School of Medicine, Durham, NC 27710, USA
BJU Int 102:964-8. 2008....
Is a positive bladder neck margin truly a T4 lesion in the prostate specific antigen era? Results from the SEARCH DatabaseW Cooper Buschemeyer
Department of Surgery Division of Urologic Surgery, Duke University School of Medicine and Urology Section, Surgical Service, Veterans Affairs Medical Center Durham, Durham, North Carolina 27710, USA
J Urol 179:124-9; discussion 129. 2008..We examined the association between positive bladder neck margins and prostate specific antigen recurrence relative to other pathological findings...
Race, biochemical disease recurrence, and prostate-specific antigen doubling time after radical prostatectomy: results from the SEARCH databaseRobert J Hamilton
Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
Cancer 110:2202-9. 2007..To address this issue, the authors examined racial differences in pathologic features, time to disease recurrence, and prostate-specific antigen (PSA) doubling time (PSADT) among a cohort of patients treated with RP...
Biochemical recurrence after localized treatmentChristopher L Amling
Division of Urology, University of Alabama, South Birmingham, AL 35294 3411, USA
Urol Clin North Am 33:147-59, v. 2006..Some treatment strategies discussed in this article include salvage radiotherapy after radical prostatectomy, salvage therapy after radiotherapy, and hormonal therapy...
Clinical and pathologic outcome after radical prostatectomy for prostate cancer patients with a preoperative Gleason sum of 8 to 10Patrick J Bastian
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Cancer 107:1265-72. 2006..Whereas multimodal therapy has often meant radiation plus hormonal therapy, newer possibilities for multimodal therapy exist such as surgery with neoadjuvant or adjuvant chemohormonal therapy or surgery with adjuvant radiation...
Is biopsy Gleason score independently associated with biochemical progression following radical prostatectomy after adjusting for pathological Gleason score?Nicholas J Fitzsimons
Division of Urologic Surgery, Duke Prostate Center, University Medical Center, Duke University School of Medicine, Durham, NC 27710, USA
J Urol 176:2453-8; discussion 2458. 2006..However, it is unclear whether it remains associated with outcome after surgery when the pathological Gleason score is known...
Changing nature of high risk patients undergoing radical prostatectomyChristopher J Kane
Urology Section, Department of Surgery, Veterans Administration Medical Center San Francisco, San Francisco, USA
J Urol 177:113-7. 2007..We examined the outcomes of radical prostatectomy alone in high risk patients with prostate cancer and evaluated changes in high risk prostate cancer outcomes with time...
Upgrading and downgrading of prostate needle biopsy specimens: risk factors and clinical implicationsStephen J Freedland
Department of Surgery, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
Urology 69:495-9. 2007..Given the critical role that needle biopsy plays in treatment decisions, we sought to determine the risk factors for upgrading and downgrading the prostate biopsy specimen...
Optimal timing, cutoff, and method of calculation of preoperative prostate-specific antigen velocity to predict relapse after prostatectomy: a report from SEARCHChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:732-7. 2007..We studied the timing, cutoff levels, and method of calculation to better define its usefulness...
Predicting unilateral prostate cancer based on biopsy features: implications for focal ablative therapy--results from the SEARCH databaseCharles D Scales
Department of Surgery Division of Urologic Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
J Urol 178:1249-52. 2007..However, few studies have assessed the correlation between biopsy parameters and pathological outcome (unilateral vs bilateral disease)...
Impact of obesity on the utility of preoperative prostate-specific antigen velocity to predict for relapse after prostatectomy: a report from the SEARCH databaseChristopher R King
Division of Urologic Oncology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:921-6. 2007....
PSA in the new millennium: a powerful predictor of prostate cancer prognosis and radical prostatectomy outcomes--results from the SEARCH databaseStephen J Freedland
Urology Section, Veterans Affairs Medical Center, Durham, NC, USA
Eur Urol 53:758-64; discussion 765-6. 2008..We examined the prognostic significance of preoperative PSA to predict pathologic stage and biochemical progression among men undergoing radical prostatectomy in the new millennium (2000-2006)...
Risk stratification of men with Gleason score 7 to 10 tumors by primary and secondary Gleason score: results from the SEARCH databaseDavid E Kang
Division of Urologic Surgery, Department of Surgery and Duke Prostate Center, Duke University School of Medicine, Durham, North Carolina, USA
Urology 70:277-82. 2007..Whether the increased risk associated with Gleason score 4+3 disease is equivalent to that of Gleason score 4+4 or greater is unclear...
Body mass index, prostate weight and transrectal ultrasound prostate volume accuracyKamran P Sajadi
Augusta Veterans Affairs Medical Center and Medical College of Georgia, Augusta, Georgia 30912, USA
J Urol 178:990-5. 2007..We hypothesized that obesity may represent a technical challenge when performing transrectal ultrasound that decreases the accuracy of estimating prostate volume...
Prostate-specific antigen and detection of prostate cancer: What have we learned and what should we recommend for screening?Christopher L Amling
Division of Urology, FOT 1105, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294, USA
Curr Treat Options Oncol 7:337-45. 2006..It is hoped that ongoing prospective screening trials will determine the value of PSA screening. However, until these results are available the controversy will continue, and men will continue to be screened...
Dilemmas in management of the small renal massChristopher L Amling
Curr Opin Urol 16:315-6. 2006
Do racial differences in prostate size explain higher serum prostate-specific antigen concentrations among black men?John C Mavropoulos
Department of Pathology, Duke University School of Medicine, Durham, North Carolina 27710, USA
Urology 69:1138-42. 2007..To determine whether elevated serum prostate-specific antigen (PSA) values in black men are due, at least partially, to larger prostate size among black men...
Current decision-making in prostate cancer therapyJared Cox
Department of Surgery Division of Urology, University of Alabama at Birmingham, Alabama 35294, USA
Curr Opin Urol 18:275-8. 2008..Several options exist for the treatment of localized prostate cancer, and this review discusses the decision-making process facing patients diagnosed with this disease...
Computerized tomographic angiography for renal donor evaluation leads to a higher exclusion rateAndrew M Strang
Division of Urology, University of Alabama at Birmingham, Birmingham, Alabama 35294 3296, USA
J Urol 177:1826-9. 2007..We compared the exclusion rate for potential living renal donors evaluated with computerized tomography angiography and radionuclide renal scintigraphy (renal scan) vs excretory urogram, renal scan and renal arteriography...
