Sudarshan R Jadcherla

Summary

Affiliation: Nationwide Children's Hospital
Country: USA

Publications

  1. ncbi request reprint Esophageal reflexes modulate frontoparietal response in neonates: Novel application of concurrent NIRS and provocative esophageal manometry
    Sudarshan R Jadcherla
    Divisions of Neonatology and Pediatric Gastroenterology and Nutrition, Nationwide Children s Hospital, Columbus, Ohio Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio
    Am J Physiol Gastrointest Liver Physiol 307:G41-9. 2014
  2. pmc Maturation of upstream and downstream esophageal reflexes in human premature neonates: the role of sleep and awake states
    Sudarshan R Jadcherla
    The Ohio State Univ College of Medicine, Section of Neonatology, Pediatric Gastroenterology and Nutrition, The Research Institute at Nationwide Children s Hospital, 700 Children s Dr, Columbus, OH 43205
    Am J Physiol Gastrointest Liver Physiol 305:G649-58. 2013
  3. pmc Physiology of esophageal sensorimotor malfunctions in neonatal neurological illness
    Sudarshan R Jadcherla
    Section of Neonatology, The Ohio State University College of Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    Am J Physiol Gastrointest Liver Physiol 304:G574-82. 2013
  4. pmc Pathophysiology of aerodigestive pulmonary disorders in the neonate
    Sudarshan R Jadcherla
    The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, The Ohio State University Wexner College of Medicine, 700 Children s Drive, Columbus, OH 43205, USA
    Clin Perinatol 39:639-54. 2012
  5. pmc Impact of feeding strategies on the frequency and clearance of acid and nonacid gastroesophageal reflux events in dysphagic neonates
    Sudarshan R Jadcherla
    Section of Neonatology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43205, USA
    JPEN J Parenter Enteral Nutr 36:449-55. 2012
  6. pmc Impact of personalized feeding program in 100 NICU infants: pathophysiology-based approach for better outcomes
    Sudarshan R Jadcherla
    Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Research Institute at Nationwide Children s Hospital, Section of Neonatology, Ohio State University College of Medicine, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 54:62-70. 2012
  7. pmc Esophageal sensation in premature human neonates: temporal relationships and implications of aerodigestive reflexes and electrocortical arousals
    Sudarshan R Jadcherla
    Sections of Neonatology, Pediatric Gastroenterology, and Nutrition, The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Department of Pediatrics, The Ohio State University College of Medicine, The Research Institute at Nationwide Children s Hospital, Columbus 43205, USA
    Am J Physiol Gastrointest Liver Physiol 302:G134-44. 2012
  8. pmc Significance of gastroesophageal refluxate in relation to physical, chemical, and spatiotemporal characteristics in symptomatic intensive care unit neonates
    Sudarshan R Jadcherla
    Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Pediatr Res 70:192-8. 2011
  9. pmc Evaluation and management of neonatal dysphagia: impact of pharyngoesophageal motility studies and multidisciplinary feeding strategy
    Sudarshan R Jadcherla
    Ohio State University College of Medicine, Columbus, OH, USA
    J Pediatr Gastroenterol Nutr 48:186-92. 2009
  10. pmc Definition and implications of novel pharyngo-glottal reflex in human infants using concurrent manometry ultrasonography
    Sudarshan R Jadcherla
    Sections of Neonatology, Pediatric Gastroenterology and Nutrition, Center for Perinatal Research, Nationwide Children s Hospital, The Ohio State University College of Medicine, 700 Children s Drive, Columbus, Ohio 43205, USA
    Am J Gastroenterol 104:2572-82. 2009

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Esophageal reflexes modulate frontoparietal response in neonates: Novel application of concurrent NIRS and provocative esophageal manometry
    Sudarshan R Jadcherla
    Divisions of Neonatology and Pediatric Gastroenterology and Nutrition, Nationwide Children s Hospital, Columbus, Ohio Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio
    Am J Physiol Gastrointest Liver Physiol 307:G41-9. 2014
    ..Deglutition contrasting with secondary peristalsis is related to cortical activation, thus implicating higher hierarchical aerodigestive protective functional neural networks. ..
  2. pmc Maturation of upstream and downstream esophageal reflexes in human premature neonates: the role of sleep and awake states
    Sudarshan R Jadcherla
    The Ohio State Univ College of Medicine, Section of Neonatology, Pediatric Gastroenterology and Nutrition, The Research Institute at Nationwide Children s Hospital, 700 Children s Dr, Columbus, OH 43205
    Am J Physiol Gastrointest Liver Physiol 305:G649-58. 2013
    ..Sleep further modulates the frequency recruitment and the type of aerodigestive reflexes. ..
  3. pmc Physiology of esophageal sensorimotor malfunctions in neonatal neurological illness
    Sudarshan R Jadcherla
    Section of Neonatology, The Ohio State University College of Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    Am J Physiol Gastrointest Liver Physiol 304:G574-82. 2013
    ....
  4. pmc Pathophysiology of aerodigestive pulmonary disorders in the neonate
    Sudarshan R Jadcherla
    The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, The Ohio State University Wexner College of Medicine, 700 Children s Drive, Columbus, OH 43205, USA
    Clin Perinatol 39:639-54. 2012
    ..Objective evaluation of aerodigestive reflexes and symptom correlation may provide support for evidence-based personalized management of feeding and airway protection strategies...
  5. pmc Impact of feeding strategies on the frequency and clearance of acid and nonacid gastroesophageal reflux events in dysphagic neonates
    Sudarshan R Jadcherla
    Section of Neonatology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43205, USA
    JPEN J Parenter Enteral Nutr 36:449-55. 2012
    ....
  6. pmc Impact of personalized feeding program in 100 NICU infants: pathophysiology-based approach for better outcomes
    Sudarshan R Jadcherla
    Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Research Institute at Nationwide Children s Hospital, Section of Neonatology, Ohio State University College of Medicine, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 54:62-70. 2012
    ....
  7. pmc Esophageal sensation in premature human neonates: temporal relationships and implications of aerodigestive reflexes and electrocortical arousals
    Sudarshan R Jadcherla
    Sections of Neonatology, Pediatric Gastroenterology, and Nutrition, The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Department of Pediatrics, The Ohio State University College of Medicine, The Research Institute at Nationwide Children s Hospital, Columbus 43205, USA
    Am J Physiol Gastrointest Liver Physiol 302:G134-44. 2012
    ..Aerodigestive homeostasis is defended by multiple tiers of aerodigestive safety mechanisms, and when esophageal reflexes are delayed, cortical hypervigilance (ECAs) occurs...
  8. pmc Significance of gastroesophageal refluxate in relation to physical, chemical, and spatiotemporal characteristics in symptomatic intensive care unit neonates
    Sudarshan R Jadcherla
    Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Pediatr Res 70:192-8. 2011
    ..001). In conclusion, clinical significance of symptoms as measured by SSI and SI and characterization of spatial-temporal-physical-chemical nature of GER events as defined by pH-impedance methods clarifies the definition of GERD...
  9. pmc Evaluation and management of neonatal dysphagia: impact of pharyngoesophageal motility studies and multidisciplinary feeding strategy
    Sudarshan R Jadcherla
    Ohio State University College of Medicine, Columbus, OH, USA
    J Pediatr Gastroenterol Nutr 48:186-92. 2009
    ..Our aims were to determine pharyngoesophageal motility correlates in neonates with dysphagia and the impact of multidisciplinary feeding strategy...
  10. pmc Definition and implications of novel pharyngo-glottal reflex in human infants using concurrent manometry ultrasonography
    Sudarshan R Jadcherla
    Sections of Neonatology, Pediatric Gastroenterology and Nutrition, Center for Perinatal Research, Nationwide Children s Hospital, The Ohio State University College of Medicine, 700 Children s Drive, Columbus, Ohio 43205, USA
    Am J Gastroenterol 104:2572-82. 2009
    ..Glottal relationships during swallowing dominate the etiology of dysphagia. We investigated the pharyngo-glottal relationships during basal and adaptive swallowing...
  11. ncbi request reprint Esophago-glottal closure reflex in human infants: a novel reflex elicited with concurrent manometry and ultrasonography
    Sudarshan R Jadcherla
    Sections of Neonatology, Pediatric Gastroenterology and Nutrition at the Columbus Children s Hospital, Department of Pediatrics, Columbus Children s Hospital, Columbus, Ohio, USA
    Am J Gastroenterol 102:2286-93. 2007
    ..We tested the hypotheses that glottal response is related to the type of esophageal peristaltic response, stimulus volume, and respiratory phase...
  12. pmc Effect of postnatal maturation on the mechanisms of esophageal propulsion in preterm human neonates: primary and secondary peristalsis
    Alankar Gupta
    Center for Perinatal Research, Nationwide Children s Hospital Research Institute, Columbus, Ohio 43205, USA
    Am J Gastroenterol 104:411-9. 2009
    ..We tested the hypotheses that: (i) maturation modifies esophageal bolus propulsion characteristics, and (ii) the mechanistic characteristics differ between primary and secondary peristalsis...
  13. pmc Lower esophageal sphincter relaxation reflex kinetics: effects of peristaltic reflexes and maturation in human premature neonates
    Eneysis M Pena
    Nationwide Children s Hospital, The Ohio State University College of Medicine, USA
    Am J Physiol Gastrointest Liver Physiol 299:G1386-95. 2010
    ..Maturation modulates an increased recruitment of inhibitory pathways that favor LESR...
  14. ncbi request reprint Antroduodenal motility and feeding outcome among neonatal extracorporeal membrane oxygenation survivors
    Sudarshan R Jadcherla
    Division of Neonatology and Pediatric Gastroenterology and Nutrition, Columbus Children s Hospital and Children s Research Institute, Department of Pediatrics at the OSU, Columbus, Ohio 43205, USA
    J Pediatr Gastroenterol Nutr 41:347-50. 2005
    ..Feeding difficulties are common among survivors of extracorporeal membrane oxygenation (ECMO). In this study, we characterized antroduodenal motor patterns and feeding outcomes among 10 ECMO survivors...
  15. pmc Physiology and pathophysiology of glottic reflexes and pulmonary aspiration: from neonates to adults
    Sudarshan R Jadcherla
    Department of Pediatrics, Sections of Neonatology, Pediatric Gastroenterology, and Nutrition, The Ohio State University College of Medicine, Columbus, OH 43205, USA
    Semin Respir Crit Care Med 31:554-60. 2010
    ..We also discuss recent advances in our understanding of glottal reflexes and the relationship of these reflexes to developmental anatomy and physiology, the pathophysiology of aspiration, and aerodigestive interactions...
  16. doi request reprint Spatiotemporal characteristics of acid refluxate and relationship to symptoms in premature and term infants with chronic lung disease
    Sudarshan R Jadcherla
    Section of Neonatology, Center for Perinatal Research, Department of Pediatrics, The Ohio State University College of Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Am J Gastroenterol 103:720-8. 2008
    ..0) with symptoms in CLD. We tested the hypothesis that in infants with CLD, AREs into the pharynx are associated with increased symptom occurrence and delayed clearance...
  17. ncbi request reprint Manometric evaluation of esophageal-protective reflexes in infants and children
    Sudarshan R Jadcherla
    Children s Research Institute, Columbus Children s Hospital, Department of Pediatrics, College of Medicine and Public Health, Ohio State University, Columbus 43205, USA
    Am J Med 115:157S-160S. 2003
    ....
  18. ncbi request reprint Upstream effect of esophageal distention: effect on airway
    Sudarshan R Jadcherla
    Section of Neonatology and Pediatric Gastroenterology and Nutrition, Columbus Children s Hospital, OH 43205, USA
    Curr Gastroenterol Rep 8:190-4. 2006
    ..Recent advances in methods to evaluate aerodigestive responses in infants that have been validated are discussed...
  19. doi request reprint Esophageal mechanosensitive mechanisms are impaired in neonates with hypoxic-ischemic encephalopathy
    Crystal D Hill
    Section of Neonatology, Department of Pediatrics, The Ohio State University College of Medicine and Public Health, Columbus, OH, USA
    J Pediatr 162:976-82. 2013
    ..As a secondary aim, we tested the hypothesis that infants with HIE receiving therapeutic hypothermia had different aerodigestive reflex characteristics than infants with HIE who received traditional neonatal care...
  20. ncbi request reprint Mechanical small bowel obstruction in premature infants diagnosed by intestinal manometry
    Sudarshan R Jadcherla
    Division of Neonatology, Columbus Children s Hospital and Department of Pediatrics at The Ohio State University School of Medicine and Public Health, Columbus, Ohio 43205, USA
    J Pediatr Gastroenterol Nutr 41:247-50. 2005
  21. ncbi request reprint Correlation of glottal closure using concurrent ultrasonography and nasolaryngoscopy in children: a novel approach to evaluate glottal status
    Sudarshan R Jadcherla
    Section of Neonatology, Pediatric Gastroenterology and Nutrition, Columbus Children s Hospital, Columbus, Ohio 43205, USA
    Dysphagia 21:75-81. 2006
    ..Our objective was to determine the temporal correlation between concurrent nasolaryngoscopy (NLS) and ultrasonography (USG) evaluation of glottal motion...
  22. ncbi request reprint Studies of feeding intolerance in very low birth weight infants: definition and significance
    Sudarshan R Jadcherla
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Pediatrics 109:516-7. 2002