Yungui Huang

Summary

Affiliation: Nationwide Children's Hospital
Country: USA

Publications

  1. pmc Employing MCMC under the PPL framework to analyze sequence data in large pedigrees
    Yungui Huang
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital Columbus, OH, USA
    Front Genet 4:59. 2013
  2. doi request reprint Association statistics under the PPL framework
    Yungui Huang
    The Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Genet Epidemiol 34:835-45. 2010
  3. pmc SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility
    Huiling He
    Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA
    J Clin Endocrinol Metab 98:E973-80. 2013
  4. pmc KELVIN: a software package for rigorous measurement of statistical evidence in human genetics
    Veronica J Vieland
    Battelle Center for Mathematical Medicine, Research Institute at Nationwide Children s Hospital, Ohio State University, 700 Children s Drive, Columbus, OH 43205, USA
    Hum Hered 72:276-88. 2011
  5. ncbi request reprint Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky
    Christopher W Bartlett
    Center for Quantitative and Computational Biology and Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA
    Genet Epidemiol 31:S61-7. 2007
  6. pmc Meta-analysis of repository data: impact of data regularization on NIMH schizophrenia linkage results
    Kimberly A Walters
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 9:e84696. 2014
  7. pmc Exploiting gene x gene interaction in linkage analysis
    Yungui Huang
    Center for Quantitative and Computational Biology, Columbus Children s Research Institute, 700 Children s Drive, Columbus, Ohio 43205, USA
    BMC Proc 1:S64. 2007
  8. pmc A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications
    Veronica J Vieland
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    Am J Hum Genet 82:1349-56. 2008

Collaborators

Detail Information

Publications8

  1. pmc Employing MCMC under the PPL framework to analyze sequence data in large pedigrees
    Yungui Huang
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital Columbus, OH, USA
    Front Genet 4:59. 2013
    ..We illustrate both the positional mapping template, as well as the efficacy of the hybrid algorithm, in application to a single large pedigree with phenotypes simulated under a two-locus trait model...
  2. doi request reprint Association statistics under the PPL framework
    Yungui Huang
    The Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Genet Epidemiol 34:835-45. 2010
    ..Here we examine the performance of the proposed LD statistics using simulated data, as well as assessing the effects of key modeling violations on this performance...
  3. pmc SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility
    Huiling He
    Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA
    J Clin Endocrinol Metab 98:E973-80. 2013
    ..Papillary thyroid carcinoma (PTC) shows high heritability, yet efforts to find predisposing genes have been largely negative...
  4. pmc KELVIN: a software package for rigorous measurement of statistical evidence in human genetics
    Veronica J Vieland
    Battelle Center for Mathematical Medicine, Research Institute at Nationwide Children s Hospital, Ohio State University, 700 Children s Drive, Columbus, OH 43205, USA
    Hum Hered 72:276-88. 2011
    ....
  5. ncbi request reprint Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky
    Christopher W Bartlett
    Center for Quantitative and Computational Biology and Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA
    Genet Epidemiol 31:S61-7. 2007
    ..The difficulty of using (primarily) affected sib pair data in a gene x gene interaction analysis is explored...
  6. pmc Meta-analysis of repository data: impact of data regularization on NIMH schizophrenia linkage results
    Kimberly A Walters
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 9:e84696. 2014
    ..These results have implications for analyses based on other types of data (e.g., case-control GWAS or sequencing data) as well as data obtained from other repositories. ..
  7. pmc Exploiting gene x gene interaction in linkage analysis
    Yungui Huang
    Center for Quantitative and Computational Biology, Columbus Children s Research Institute, 700 Children s Drive, Columbus, Ohio 43205, USA
    BMC Proc 1:S64. 2007
    ..This suggests that gene x gene interactions could be effectively used in quantitative trait analyses even when families have been ascertained as ASPs for a related dichotomous trait...
  8. pmc A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications
    Veronica J Vieland
    Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    Am J Hum Genet 82:1349-56. 2008
    ..This model has several clinical implications, which we believe will prove relevant to other complex diseases as well...