Peter J Giannone

Summary

Affiliation: Nationwide Children's Hospital
Country: USA

Publications

  1. pmc Maternal preeclampsia and neonatal outcomes
    Carl H Backes
    Department of Pediatrics, College of Medicine, The Ohio State University and Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH 43205, USA
    J Pregnancy 2011:214365. 2011
  2. pmc Cellular strain amplifies LPS-induced stress signaling in immature enterocytes: potential implications for preterm infant NCPAP
    Alicia M Alcamo
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Pediatr Res 72:256-61. 2012
  3. ncbi request reprint Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis
    Peter J Giannone
    Department of Pediatrics at Centers for Cardiovascular Medicine, Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 48:276-82. 2009
  4. pmc Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis
    Peter J Giannone
    Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatr Res 70:67-71. 2011
  5. ncbi request reprint Endothelin-1 in human intestine resected for necrotizing enterocolitis
    Philip T Nowicki
    Center for Cell and Vascular Biology, Columbus Children s Research Institute, Department of Pediatrics, Division of Neonatology, Ohio State University, USA
    J Pediatr 146:805-10. 2005
  6. ncbi request reprint Effects of prenatal lipopolysaccharide exposure on epithelial development and function in newborn rat intestine
    Peter J Giannone
    Section of Neonatology, Department of Pediatrics, Center for Cardiovascular Medicine, Columbus Children s Research Institute, Columbus, Ohio 43205, USA
    J Pediatr Gastroenterol Nutr 43:284-90. 2006
  7. ncbi request reprint Endothelial nitric oxide synthase in human intestine resected for necrotizing enterocolitis
    Philip T Nowicki
    Department of Pediatrics, Department of Surgery, The Ohio State University, Columbus, Ohio, USA
    J Pediatr 150:40-5. 2007
  8. pmc LPS-binding protein enables intestinal epithelial restitution despite LPS exposure
    Juli M Richter
    Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 54:639-44. 2012
  9. ncbi request reprint Intestinal O2 consumption in necrotizing enterocolitis: role of nitric oxide
    Philip T Nowicki
    Department of Pediatrics, Ohio State University, Columbus, Ohio 43205, USA
    Pediatr Res 59:500-5. 2006
  10. ncbi request reprint Mean arterial pressure in concordant and discordant triplets during the first week of life
    Leandro Cordero
    Division of Neonatal Perinatal Medicine, Pediatrics and Obstetrics, The Ohio State University Medical Center, Columbus, OH 43210 1228, USA
    J Perinatol 25:198-204. 2005

Collaborators

Detail Information

Publications18

  1. pmc Maternal preeclampsia and neonatal outcomes
    Carl H Backes
    Department of Pediatrics, College of Medicine, The Ohio State University and Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH 43205, USA
    J Pregnancy 2011:214365. 2011
    ..Reviewed is the current literature in the diagnosis and obstetrical management of preeclampsia, the outcomes of late-preterm infants, and potential strategies to optimize fetal outcomes in pregnancies complicated by preeclampsia...
  2. pmc Cellular strain amplifies LPS-induced stress signaling in immature enterocytes: potential implications for preterm infant NCPAP
    Alicia M Alcamo
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Pediatr Res 72:256-61. 2012
    ..We tested the hypothesis that mechanical strain causes an exaggerated enterocyte inflammatory response and decreased enterocyte growth and proliferation in the absence and presence of lipopolysaccharide (LPS)...
  3. ncbi request reprint Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis
    Peter J Giannone
    Department of Pediatrics at Centers for Cardiovascular Medicine, Research Institute at Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 48:276-82. 2009
    ..An increased incidence of necrotizing enterocolitis (NEC) has been noted in infants who are born to mothers with chorioamnionitis...
  4. pmc Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis
    Peter J Giannone
    Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Pediatr Res 70:67-71. 2011
    ..We speculate that PARP-1 overactivation in NEC may drive mucosal cell death in this disease and that PARP-1 may be a novel therapeutic target in NEC...
  5. ncbi request reprint Endothelin-1 in human intestine resected for necrotizing enterocolitis
    Philip T Nowicki
    Center for Cell and Vascular Biology, Columbus Children s Research Institute, Department of Pediatrics, Division of Neonatology, Ohio State University, USA
    J Pediatr 146:805-10. 2005
    ..We then evaluated if ET-1 participates in hemodynamic regulation within intestinal subserosal arterioles harvested from portions of human preterm intestine that demonstrate NEC...
  6. ncbi request reprint Effects of prenatal lipopolysaccharide exposure on epithelial development and function in newborn rat intestine
    Peter J Giannone
    Section of Neonatology, Department of Pediatrics, Center for Cardiovascular Medicine, Columbus Children s Research Institute, Columbus, Ohio 43205, USA
    J Pediatr Gastroenterol Nutr 43:284-90. 2006
    ..Maternal infection during pregnancy is associated with several neonatal morbidities, including periventricular leukomalacia and lung maldevelopment and injury...
  7. ncbi request reprint Endothelial nitric oxide synthase in human intestine resected for necrotizing enterocolitis
    Philip T Nowicki
    Department of Pediatrics, Department of Surgery, The Ohio State University, Columbus, Ohio, USA
    J Pediatr 150:40-5. 2007
    ..To determine the expression and function of endothelial nitric oxide synthase (eNOS) in submucosal arterioles harvested from human intestine resected for necrotizing enterocolitis (NEC) or congenital bowel disease...
  8. pmc LPS-binding protein enables intestinal epithelial restitution despite LPS exposure
    Juli M Richter
    Center for Perinatal Research, The Research Institute at Nationwide Children s Hospital, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Gastroenterol Nutr 54:639-44. 2012
    ..We sought to determine how LBP would affect wound healing in an in vitro model of intestinal cell restitution and protect against intestinal injury in a rodent model of NEC...
  9. ncbi request reprint Intestinal O2 consumption in necrotizing enterocolitis: role of nitric oxide
    Philip T Nowicki
    Department of Pediatrics, Ohio State University, Columbus, Ohio 43205, USA
    Pediatr Res 59:500-5. 2006
    ..We conclude that iNOS-derived NO suppresses VO2 in intestine resected for NEC that demonstrates a relatively normal histology on light microscopy...
  10. ncbi request reprint Mean arterial pressure in concordant and discordant triplets during the first week of life
    Leandro Cordero
    Division of Neonatal Perinatal Medicine, Pediatrics and Obstetrics, The Ohio State University Medical Center, Columbus, OH 43210 1228, USA
    J Perinatol 25:198-204. 2005
    ..To retrospectively determine mean arterial pressure (MAP) for stable concordant and discordant triplets during the first 7 days of life...
  11. doi request reprint The neonatal intestinal vasculature: contributing factors to necrotizing enterocolitis
    Craig A Nankervis
    Center for Perinatal Research, Nationwide Children s Hospital, Columbus, OH, USA
    Semin Perinatol 32:83-91. 2008
    ..Strategies focused on maintaining the delicate balance favoring vasodilation in the newborn intestinal circulation may prove to be useful in the prevention and treatment of NEC...
  12. ncbi request reprint Use of polyethylene bags in extremely low birth weight infant resuscitation for the prevention of hypothermia
    Patrick D Carroll
    Department of Pediatrics, College of Medicine, Ohio State University, Columbus 43210 1228, USA
    J Reprod Med 55:9-13. 2010
    ..To compare the clinical responses of extremely low birth weight (ELBW) infants resuscitated in polyethylene bags with ELBW infants who were resuscitated using traditional temperature control measures...
  13. doi request reprint Decreased cardiac expression of vascular endothelial growth factor and redox imbalance in murine diabetic cardiomyopathy
    Bing Han
    Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Am J Physiol Heart Circ Physiol 297:H829-35. 2009
    ....
  14. doi request reprint Breastfeeding in women with severe preeclampsia
    Leandro Cordero
    Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio 43210 1228, USA
    Breastfeed Med 7:457-63. 2012
    ..This study examined feeding practices and factors associated with breastfeeding initiation in 281 women with SP and their 200 late-preterm and 81 term infants...
  15. ncbi request reprint Probiotics and prebiotics for the prevention of necrotizing enterocolitis
    Michael R Stenger
    Department of Pediatrics, The Ohio State University College of Medicine and Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    Curr Infect Dis Rep 13:13-20. 2011
    ..These preliminary studies support the need for a large, randomized, controlled trial to further investigate the role of probiotics in the prevention of NEC...
  16. doi request reprint Necrotizing enterocolitis in neonates with congenital heart disease
    Peter J Giannone
    Section of Neonatology, Nationwide Children s Hospital and Research Institute, Columbus, OH 43205, USA
    Life Sci 82:341-7. 2008
    ..In this article, we review the pathogenesis of NEC and CHD including associated mortality and morbidities and discuss possible mechanisms linking these two disease states...
  17. ncbi request reprint Mean arterial pressure in very low birth weight (801 to 1500 g) concordant and discordant twins during the first day of life
    Leandro Cordero
    Division of Neonatal Perinatal Medicine, Pediatrics and Obstetrics, Department of Pediatrics, The Ohio State University Medical Center, N118 Doan Hall, 410 W 10th Avenue, Columbus, OH 43210 1228, USA
    J Perinatol 23:545-51. 2003
    ..To determine retrospectively mean arterial pressure (MAP) for stable and unstable concordant and discordant very low birth weight (VLBW: 801 to 1500 g) twins during the first 24 hours of life...
  18. doi request reprint Necrotizing enterocolitis in neonates undergoing the hybrid approach to complex congenital heart disease
    Wendy A Luce
    Department of Pediatrics, Ohio State University, Columbus, OH, USA
    Pediatr Crit Care Med 12:46-51. 2011
    ..The hybrid procedure is another palliative option for hypoplastic left-heart syndrome, but NEC in neonates undergoing this procedure has not been reported...