Brian Becknell

Summary

Affiliation: Nationwide Children's Hospital
Country: USA

Publications

  1. doi request reprint Impact of urinary tract infection on inpatient healthcare for congenital obstructive uropathy
    Brian Becknell
    Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43201, USA
    J Pediatr Urol 8:470-6. 2012
  2. doi request reprint Hepatoblastoma and prune belly syndrome: a potential association
    Brian Becknell
    Department of Pediatrics, Ohio State University College of Medicine, Columbus, OH 43205, USA
    Pediatr Nephrol 26:1269-73. 2011
  3. pmc Molecular basis of renal adaptation in a murine model of congenital obstructive nephropathy
    Brian Becknell
    Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America Division of Pediatric Nephrology, Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 8:e72762. 2013
  4. pmc Struvite urolithiasis and chronic urinary tract infection in a murine model of urinary diversion
    Brian Becknell
    Division of Nephrology, Department of Pediatrics, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Urology 81:943-8. 2013
  5. doi request reprint The demographics and costs of inpatient vesicoureteral reflux management in the USA
    John David Spencer
    Pediatric Nephrology Fellowship Program, Nationwide Children s Hospital, The Ohio State University, Columbus, OH, USA
    Pediatr Nephrol 26:1995-2001. 2011
  6. pmc Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract
    Brian Becknell
    1 Division of Nephrology, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, USA 2 Center for Clinical and Translational Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, USA
    Kidney Int 87:151-61. 2015
  7. doi request reprint Ultrasound imaging of the murine kidney
    Ashley R Carpenter
    Center for Molecular and Human Genetics, Research Institute at Nationwide Children s Hospital, Columbus, OH, USA
    Methods Mol Biol 886:403-10. 2012
  8. pmc The innate immune response during urinary tract infection and pyelonephritis
    John David Spencer
    Department of Pediatrics, Division of Nephrology, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    Pediatr Nephrol 29:1139-49. 2014
  9. pmc Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract
    Brian Becknell
    Section of Nephrology, Nationwide Children s Hospital, Columbus, Ohio, United States of America Center for Clinical and Translational Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 8:e77714. 2013
  10. doi request reprint The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections
    Brian Becknell
    Department of Pediatrics, Division of Nephrology, Nationwide Children s Hospital, Columbus, OH, USA
    Expert Rev Anti Infect Ther 13:81-90. 2015

Detail Information

Publications13

  1. doi request reprint Impact of urinary tract infection on inpatient healthcare for congenital obstructive uropathy
    Brian Becknell
    Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43201, USA
    J Pediatr Urol 8:470-6. 2012
    ..Urinary tract infections (UTIs) pose a risk for ascending infections and CKD in patients with COU. We evaluated the impact of comorbid UTIs on hospital charges and length of stay (LOS) for pediatric COU discharges...
  2. doi request reprint Hepatoblastoma and prune belly syndrome: a potential association
    Brian Becknell
    Department of Pediatrics, Ohio State University College of Medicine, Columbus, OH 43205, USA
    Pediatr Nephrol 26:1269-73. 2011
    ..All individuals were born after 2002. These subjects lacked genetic, natal, or environmental factors known to confer risk of HBL. The occurrence of PBS and HBL in these patients constitutes a novel potential association...
  3. pmc Molecular basis of renal adaptation in a murine model of congenital obstructive nephropathy
    Brian Becknell
    Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America Division of Pediatric Nephrology, Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 8:e72762. 2013
    ..These observations will permit the development of novel biomarkers and therapeutic approaches to progressive renal injury in the context of congenital obstruction. ..
  4. pmc Struvite urolithiasis and chronic urinary tract infection in a murine model of urinary diversion
    Brian Becknell
    Division of Nephrology, Department of Pediatrics, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Urology 81:943-8. 2013
    ..To characterize the clinical course after cutaneous vesicostomy (CV) in megabladder (mgb(-/-)) mice with functional urinary bladder obstruction...
  5. doi request reprint The demographics and costs of inpatient vesicoureteral reflux management in the USA
    John David Spencer
    Pediatric Nephrology Fellowship Program, Nationwide Children s Hospital, The Ohio State University, Columbus, OH, USA
    Pediatr Nephrol 26:1995-2001. 2011
    ..Since 2000, hospital charges for inpatient VUR management have increased. More efforts are needed to evaluate cost-effective strategies for the evaluation and management of VUR...
  6. pmc Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract
    Brian Becknell
    1 Division of Nephrology, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, USA 2 Center for Clinical and Translational Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, USA
    Kidney Int 87:151-61. 2015
    ..Our studies suggest RNase 6 serves as an evolutionarily conserved antimicrobial peptide that participates in the maintenance of urinary tract sterility. ..
  7. doi request reprint Ultrasound imaging of the murine kidney
    Ashley R Carpenter
    Center for Molecular and Human Genetics, Research Institute at Nationwide Children s Hospital, Columbus, OH, USA
    Methods Mol Biol 886:403-10. 2012
    ..We have developed a simple US-based method of detection and quantitation of hydronephrosis in a mouse model of congenital obstructive nephropathy, the megabladder (mgb) mouse...
  8. pmc The innate immune response during urinary tract infection and pyelonephritis
    John David Spencer
    Department of Pediatrics, Division of Nephrology, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    Pediatr Nephrol 29:1139-49. 2014
    ..In doing so, we focus on the role of antimicrobial peptides-a ubiquitous component of the innate immune response. ..
  9. pmc Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract
    Brian Becknell
    Section of Nephrology, Nationwide Children s Hospital, Columbus, Ohio, United States of America Center for Clinical and Translational Research, The Research Institute at Nationwide Children s Hospital, Columbus, Ohio, United States of America
    PLoS ONE 8:e77714. 2013
    ..Thus, whereas mBD-1 deficiency does not alter bladder UPEC burden in vivo, we have identified mBD-3 and mBD-14 as potential mediators of mucosal immunity in the lower urinary tract...
  10. doi request reprint The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections
    Brian Becknell
    Department of Pediatrics, Division of Nephrology, Nationwide Children s Hospital, Columbus, OH, USA
    Expert Rev Anti Infect Ther 13:81-90. 2015
    ..In this manuscript, we review the diagnosis and management of acute and recurrent UTI in the pediatric population. ..
  11. doi request reprint Trends in pediatric urolithiasis: patient characteristics, associated diagnoses, and financial burden
    Kirsten Kusumi
    Division of Nephrology, Department of Pediatrics, Nationwide Children s Hospital The Ohio State University, 700 Children s Drive, Columbus, OH, 43205, USA
    Pediatr Nephrol 30:805-10. 2015
    ..The goal of this study was to examine national trends in hospitalization, emergency department (ED) utilization, secondary diagnoses, and charges associated with pediatric urolithiasis...
  12. doi request reprint Urinary diversion via cutaneous vesicostomy in the megabladder mouse
    Ashley R Carpenter
    Center for Molecular and Human Genetics, The Research Institute at Nationwide Children s Hospital, Columbus, OH, USA
    Methods Mol Biol 886:393-402. 2012
    ....
  13. pmc Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption
    Brian Becknell
    Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43205, USA
    Kidney Int 79:120-7. 2011
    ..Hence, COL4A5 mutation analysis should be considered when glomerulonephritis presents in an X-linked inheritance pattern, even with a presentation distinct from Alport syndrome...