Zhigang Zhou

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi QSAR models for predicting cathepsin B inhibition by small molecules--continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    J Mol Graph Model 28:714-27. 2010
  2. ncbi Multi-conformation 3D QSAR study of benzenesulfonyl-pyrazol-ester compounds and their analogs as cathepsin B inhibitors
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health Bethesda, MD 20894, USA
    J Mol Graph Model 30:135-47. 2011
  3. ncbi Structure-based virtual screening for drug discovery: a problem-centric review
    Tiejun Cheng
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA
    AAPS J 14:133-41. 2012
  4. ncbi Computational analysis of the cathepsin B inhibitors activities through LR-MMPBSA binding affinity calculation based on docked complex
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institute of Health, Bethesda, Maryland 20894, USA
    J Comput Chem 30:2165-75. 2009
  5. ncbi PubChem's BioAssay Database
    Yanli Wang
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D400-12. 2012

Detail Information

Publications5

  1. ncbi QSAR models for predicting cathepsin B inhibition by small molecules--continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    J Mol Graph Model 28:714-27. 2010
    ....
  2. ncbi Multi-conformation 3D QSAR study of benzenesulfonyl-pyrazol-ester compounds and their analogs as cathepsin B inhibitors
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health Bethesda, MD 20894, USA
    J Mol Graph Model 30:135-47. 2011
    ..The multi-conformation method to build 3D QSAR is very effective approach to obtain satisfactory models with high correlation with experimental results and high prediction power for unknown compounds...
  3. ncbi Structure-based virtual screening for drug discovery: a problem-centric review
    Tiejun Cheng
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA
    AAPS J 14:133-41. 2012
    ....
  4. ncbi Computational analysis of the cathepsin B inhibitors activities through LR-MMPBSA binding affinity calculation based on docked complex
    Zhigang Zhou
    National Center for Biotechnology Information, National Library of Medicine, National Institute of Health, Bethesda, Maryland 20894, USA
    J Comput Chem 30:2165-75. 2009
    ..Our results also show that the results based on protein dimer show better correlations with experimental activity when compared to results based on monomer in the in silico calculations...
  5. ncbi PubChem's BioAssay Database
    Yanli Wang
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D400-12. 2012
    ..In this work, we provide an update for the PubChem BioAssay resource, including information content growth, data model extension and new developments of data submission, retrieval, analysis and download tools...