Research Topics
Species | Z ZhangSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Logistic regression analysis of biomarker data subject to pooling and dichotomizationZ Zhang
Biostatistics and Bioinformatics Branch, Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
Stat Med 31:2473-84. 2012..We make recommendations with regard to the choice of design for pooled epidemiologic studies...
A two-part model for reference curve estimation subject to a limit of detectionZ Zhang
Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
Stat Med 30:1455-65. 2011..The method is illustrated with hormone data from the Third National Health and Nutrition Examination Survey...
Binary regression analysis with pooled exposure measurements: a regression calibration approachZhiwei Zhang
Biostatistics and Bioinformatics Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
Biometrics 67:636-45. 2011..The methods are illustrated using data from the Collaborative Perinatal Project...
Uteroglobin is essential in preventing immunoglobulin A nephropathy in miceF Zheng
Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland 20892 1830, USA
Nat Med 5:1018-25. 1999..These results define an essential role for UG in preventing mouse IgA nephropathy and warrant further studies to determine if a similar mechanism(s) underlies the human disease...
Uteroglobin: physiological role in normal glomerular function uncovered by targeted disruption of the uteroglobin gene in miceA B Mukherjee
Section on Developmental Genetics, Heritable Disorders Branch, The National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892 1830, USA
Am J Kidney Dis 32:1106-20. 1998..Nevertheless, the UG gene-knockout mice provide a valuable animal model for investigation of human glomerulopathies in general and familial Fn-deposit glomerulopathy in particular...
Uteroglobin: a novel cytokine?A B Mukherjee
Section on Developmental Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
Cell Mol Life Sci 55:771-87. 1999..Molecular characterization of the UG receptor and signal transduction via this receptor pathway may show that this protein belongs to a novel cytokine/chemokine family...
Cisplatin-DNA adduct determination in the hepatic albumin gene as compared to whole genomic DNAZ Zhang
Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 4255, USA
Chem Res Toxicol 10:971-7. 1997..85 kb fragment. The data demonstrate that this 1.85 kb region containing expressed regions of the albumin gene has undergone both less adduction and more rapid adduct removal, as compared to the MH1C1 genome as a whole...
Gapped BLAST and PSI-BLAST: a new generation of protein database search programsS F Altschul
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
Nucleic Acids Res 25:3389-402. 1997..PSI-BLAST is used to uncover several new and interesting members of the BRCT superfamily...
Use of p53 transgenic mice in the development of cancer models for multiple purposesR A Lubet
Chemoprevention Branch, National Cancer Institute, Executive Plaza North, Room 201, 6130 Executive Boulevard, Bethesda, MD 20852, USA
Exp Lung Res 26:581-93. 2000....
Severe fibronectin-deposit renal glomerular disease in mice lacking uteroglobinZ Zhang
Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development NICHD, National Insitutes of Health NIH, Bethesda, MD 20892 1830, USA
Science 276:1408-12. 1997..Thus, UG is essential for maintaining normal renal function in mice, which raises the possibility that an analogous pathogenic mechanism may underlie genetic Fn-deposit human glomerular disease...
Uteroglobin binding proteins: regulation of cellular motility and invasion in normal and cancer cellsG C Kundu
Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1830, USA
Ann N Y Acad Sci 923:234-48. 2000..Taken together, our data define receptor-mediated functions of UG in which this protein regulates vital cellular functions by both autocrine and paracrine pathways...
Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteinsJ Satoi
Liver Diseases Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-1800, USA
J Virol 75:12121-7. 2001..The HCV transgenic mice can be induced by DNA immunization to generate anti-HCV antibodies and anticore CTLs. However, they are tolerant at the CTL level against the E2 protein despite DNA immunization...
Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complexZ Zhang
Liver Diseases Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 275:15157-65. 2000..Thus, interaction of HBX with the proteasome complex in metazoan cells may underlie the functional basis of proteasome as a cellular target of HBX...
Palmitoyl-protein thioesterase gene expression in the developing mouse brain and retina: implications for early loss of vision in infantile neuronal ceroid lipofuscinosisZ Zhang
Section on Developmental Genetics, Heritable Disorders Branch, NICHD, NIH, Bethesda, MD 20892 1830, USA
Gene 231:203-11. 1999..Consequently, the loss of vision occurs before the deterioration of brain functions in this disease...
Human uteroglobin gene: structure, subchromosomal localization, and polymorphismZ Zhang
Section on Developmental Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, MD 20892, USA
DNA Cell Biol 16:73-83. 1997..Moreover, the close proximity of this gene to several candidate disease genes makes it an important chromosomal marker in cloning and characterization of those genes...
