Research Topics
Genomes and GenesSpecies | Cuilin ZhangSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Prepregnancy consumption of fruits and fruit juices and the risk of gestational diabetes mellitus: a prospective cohort studyLiwei Chen
Program of Epidemiology, School of Public Health, Louisiana State University Health Science Center, New Orleans, Louisiana, USA
Diabetes Care 35:1079-82. 2012..Examine the association of prepregnancy habitual consumption of fruits and fruit juices and gestational diabetes mellitus (GDM) risk...- Effect of dietary and lifestyle factors on the risk of gestational diabetes: review of epidemiologic evidenceCuilin Zhang
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 21205, USA
Am J Clin Nutr 94:1975S-1979S. 2011..This review provides an overview of emerging diet and lifestyle factors that may contribute to the prevention of GDM. It also discusses major methodologic concerns about the available epidemiologic studies of GDM risk factors... - Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitusCuilin Zhang
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
PLoS ONE 3:e3753. 2008..Our objective is to determine the association between maternal plasma 25-[OH] D concentrations in early pregnancy and the risk for gestational diabetes mellitus (GDM)... 
Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US womenCuilin Zhang
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, 6100 Executive Blvd, Room 7B03, MSC 7510, 9000 Rockville Pike, Bethesda, MD 20892 7510, USA
Circulation 117:1658-67. 2008..However, the association of premature death resulting from these diseases with abdominal adiposity has not been widely studied, and findings are inconsistent...- Influence of endogenous reproductive hormones on F2-isoprostane levels in premenopausal women: the BioCycle StudyEnrique F Schisterman
Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Boulevard, 7B03M, Rockville, MD 20852, USA
Am J Epidemiol 172:430-9. 2010..If F(2)-isoprostanes are specific markers of oxidative stress, these results call into question the commonly held hypothesis that endogenous estradiol reduces oxidative stress... - The impact of dietary folate intake on reproductive function in premenopausal women: a prospective cohort studyAudrey J Gaskins
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland, USA
PLoS ONE 7:e46276. 2012..Our objective was to evaluate the association between dietary folate intake, hormone levels, and sporadic anovulation in healthy, regularly menstruating women... - Whole grains are associated with serum concentrations of high sensitivity C-reactive protein among premenopausal womenAudrey J Gaskins
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20852, USA
J Nutr 140:1669-76. 2010.... - A longitudinal study of serum lipoproteins in relation to endogenous reproductive hormones during the menstrual cycle: findings from the BioCycle studySunni L Mumford
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
J Clin Endocrinol Metab 95:E80-5. 2010..Exogenous estrogens have been shown to affect the lipid profile, leading to the hypothesis that endogenous estrogens may have similar effects... - Caffeinated beverage intake and reproductive hormones among premenopausal women in the BioCycle StudyKaren C Schliep
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Am J Clin Nutr 95:488-97. 2012..Caffeinated beverages are widely consumed among women of reproductive age, but their association with reproductive hormones, and whether race modifies any such associations, is not well understood... - Polymorphisms in the neuropeptide Y gene and the risk of obesity: findings from two prospective cohortsEdwina H Yeung
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Boulevard, 7B03, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 96:E2055-62. 2011..Neuropeptide Y (NPY) increases appetite and food intake in animals. Conflicting evidence has been found for the association between polymorphisms of the NPY gene and obesity in humans... - A prospective study of prepregnancy dietary fat intake and risk of gestational diabetesKatherine Bowers
Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Am J Clin Nutr 95:446-53. 2012..Fatty acids play a vital role in glucose homeostasis; however, studies on habitual dietary fat intakes and gestational diabetes mellitus (GDM) risk are limited and provide conflicting findings... - A prospective study of prepregnancy dietary iron intake and risk for gestational diabetes mellitusKatherine Bowers
Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
Diabetes Care 34:1557-63. 2011..The current study is to determine if prepregnancy dietary and supplemental iron intakes are associated with the risk of GDM... - Racial differences in the association between sex hormone-binding globulin and adiposity in premenopausal women: the BioCycle studyEdwina H Yeung
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
Diabetes Care 33:2274-6. 2010..To assess the associations between measures of adiposity and sex hormone- binding globulin (SHBG) and to evaluate whether such associations differ by race... - Longitudinal study of insulin resistance and sex hormones over the menstrual cycle: the BioCycle StudyEdwina H Yeung
Eunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Epidemiology, Statistics, and Prevention Research, Epidemiology Branch, 6100 Executive Boulevard, Room 7B03, MSC 7510, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 95:5435-42. 2010..Conflicting findings have been reported regarding the effect of menstrual cycle phase and sex hormones on insulin sensitivity... - Birth weight, postnatal weight change, and risk for high blood pressure among chinese childrenKatherine Bowers
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20852, USA
Pediatrics 127:e1272-9. 2011..Previous studies were conducted largely in Western countries however the hypothesis may also be relevant in developing countries where metabolic disorders are increasing... - Age at menarche and metabolic markers for type 2 diabetes in premenopausal women: the BioCycle StudyLiwei Chen
Department of Epidemiology, School of Public Health, Louisiana State University Health Science Center, New Orleans, Louisiana 70112, USA
J Clin Endocrinol Metab 96:E1007-12. 2011..Early age at menarche has been linked to an elevated risk of type 2 diabetes. However, the underlying mechanism is unclear... - The exposome - exciting opportunities for discoveries in reproductive and perinatal epidemiologyGermaine M Buck Louis
Division of Epidemiology, Statistics and Prevention Research, National Institutes of Health, Rockville, MD
Paediatr Perinat Epidemiol 27:229-36. 2013..Bold new conceptual frameworks such as the exposome are needed for designing research that may lead to discovery and improve population health... - Childhood size and life course weight characteristics in association with the risk of incident type 2 diabetesEdwina H Yeung
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
Diabetes Care 33:1364-9. 2010..To determine how childhood overweight, in conjunction with other life course weight characteristics, relates to the development of type 2 diabetes in adulthood... - Effect of daily fiber intake on reproductive function: the BioCycle StudyAudrey J Gaskins
Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
Am J Clin Nutr 90:1061-9. 2009..The influence of fiber on aspects of reproduction, which include ovulation, has not been well studied in premenopausal women... - Maternal serum theobromine and the development of preeclampsiaMark A Klebanoff
Epidemiology Branch, Department of Health and Human Services, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Epidemiology 20:727-32. 2009.... 
Maternal plasma ascorbic Acid (vitamin C) and risk of gestational diabetes mellitusCuilin Zhang
Department of Epidemiology, University of Washington School of Public Health and Community Medicine, Seattle, Washington, USA
Epidemiology 15:597-604. 2004..Antioxidants, particularly vitamin C (ascorbic acid), have the capacity to influence glucose tolerance. Modification of diet could reduce the likelihood of developing gestational diabetes mellitus...- Trp64Arg polymorphism of the beta3-adrenergic receptor gene, pre-pregnancy obesity and risk of pre-eclampsiaCuilin Zhang
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
J Matern Fetal Neonatal Med 17:19-28. 2005..We investigated the relation of the beta3-AR gene to pre-pregnancy obesity and risk of pre-eclampsia. The present study is a case-control study of 87 Caucasian pre-eclampsia cases and 214 controls... - The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic menLu Qi
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Diabetes 54:1607-10. 2005..0019). In conclusion, our study showed significant associations between APM1 G276T and decreased CVD risk and increased plasma adiponectin levels in diabetic men... - Interactions between the -514C->T polymorphism of the hepatic lipase gene and lifestyle factors in relation to HDL concentrations among US diabetic menCuilin Zhang
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 81:1429-35. 2005..A common polymorphism (-514C-->T) of the hepatic lipase gene (LIPC), which accounts for up to 30% of the variation in hepatic lipase activity, has been associated with low hepatic lipase activity and high HDL-cholesterol concentrations... - Hepatic lipase gene polymorphism, pre-pregnancy overweight status and risk of preeclampsia among Peruvian womenDaniel A Enquobahrie
Center for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA
Gynecol Endocrinol 21:211-7. 2005..In this study, we found that LIPC -514TT genotype and overweight status, when occurring together, were associated with a 3-fold increase in risk of preeclampsia among Peruvian women... - Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and menCuilin Zhang
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Diabetes 55:2645-8. 2006..48-fold increased risk (P < 10(-16)). Our findings confirm that the TCF7L2 gene represents an important locus for predicting inherited susceptibility to type 2 diabetes... - Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitusCuilin Zhang
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Diabetes Care 29:2223-30. 2006..We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk... - Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individualsLu Qi
Departments of Nutrition and Epidemiology, Harvard School of Public Health, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
J Clin Endocrinol Metab 92:3618-25. 2007..IL-6 (IL6) is an immune-modulating cytokine associated with obesity in humans... - Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US womenLu Qi
Department of Nutrition, Harvard School of Public Health, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Obesity (Silver Spring) 16:1061-5. 2008..The variations in perilipin gene (PLIN) were previously associated with obesity and insulin sensitivity. We examined whether PLIN variability was associated with diabetes risk and obesity status modified such associations... - Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in womenChristin Heidemann
Harvard School of Public Health, Massachusetts General Hospital, Brigham and Women s Hospital, and Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Ann Intern Med 149:307-16. 2008..Adiponectin and resistin are recently discovered adipokines that may provide a molecular link between adiposity and type 2 diabetes... - A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsiaChunfang Qiu
Center for Perinatal Studies, Swedish Medical Center, 747 Broadway, Suite 449 North, Seattle, WA 98122, USA
Am J Hypertens 17:154-60. 2004..We measured C-reactive protein (CRP), a clinical marker of systemic inflammation, in maternal serum collected at 13 weeks gestation on average, to determine whether elevations precede the clinical manifestation of preeclampsia...