Affiliation: National Institutes of Health
- Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin geneYanlin Yu
Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 5:e12710. 2010....
- The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasisYanlin Yu
Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892-4264, USA
Cancer Res 66:1982-9. 2006..Our data indicate that Ezrin represents a promising therapeutic target for patients with advanced-stage rhabdomyosarcoma and perhaps other malignancies...
- Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulatorsYanlin Yu
Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Nat Med 10:175-81. 2004..The identification of ezrin and Six-1 as critical regulators of metastasis in RMS provides new mechanistic and therapeutic insights into this pediatric cancer...