J Yewdell


Affiliation: National Institutes of Health
Country: USA


  1. Wei J, Yewdell J. Flu DRiPs in MHC Class I Immunosurveillance. Virol Sin. 2018;: pubmed publisher
  2. Angeletti D, Yewdell J. Understanding and Manipulating Viral Immunity: Antibody Immunodominance Enters Center Stage. Trends Immunol. 2018;39:549-561 pubmed publisher
  3. Hickman H, Mays J, Gibbs J, Kosik I, Magadán J, Takeda K, et al. Influenza A Virus Negative Strand RNA Is Translated for CD8+ T Cell Immunosurveillance. J Immunol. 2018;201:1222-1228 pubmed publisher
    ..Together, our findings demonstrate both the translation of sequences on the negative strand of a single-stranded RNA virus and its relevance in antiviral immunosurveillance. ..
  4. Yewdell J. DRiPs solidify: progress in understanding endogenous MHC class I antigen processing. Trends Immunol. 2011;32:548-58 pubmed publisher
    ..DRiPs enable the immune system to rapidly detect alterations in cellular gene expression with great sensitivity. ..
  5. Yewdell J. Amsterdamming DRiPs. Mol Immunol. 2013;55:110-2 pubmed publisher
    ..Here I discuss the most recent findings regarding the nature of substrates for the MHC class I antigen processing pathways which provide glimpses of the mist shrouded features remaining to be discovered. ..
  6. Yewdell J. Monoclonal antibodies specific for discontinuous epitopes direct refolding of influenza A virus hemagglutinin. Mol Immunol. 2010;47:1132-6 pubmed publisher
  7. Yewdell J. Viva la revolución: rethinking influenza a virus antigenic drift. Curr Opin Virol. 2011;1:177-83 pubmed publisher
  8. Yewdell J, Ince W. Greasing the SCIDs for universal flu antibodies. Cell Host Microbe. 2013;14:7-8 pubmed publisher
    ..As proof of principle, they isolate human mAbs that could potentially be used to treat or prevent human infection with any influenza A virus strain. ..
  9. request reprint
    Yewdell J. Immunology. Hide and seek in the peptidome. Science. 2003;301:1334-5 pubmed

More Information


  1. Yewdell J. Designing CD8+ T cell vaccines: it's not rocket science (yet). Curr Opin Immunol. 2010;22:402-10 pubmed publisher
    ..With the rapid advances in this area of research, the dawn of rational vaccine design is at hand. ..
  2. Angeletti D, Frank G, Yewdell J. Flow-Cytometric Method Measuring B Cell Surface Immunoglobulin Avidity. Methods Mol Biol. 2017;1623:181-189 pubmed publisher
    ..This method can be generally employed to include antibody avidity measurements basic and clinical studies of immunity to viruses and other medically relevant immunogens. ..
  3. Wei J, Yewdell J. Immunoribosomes: Where's there's fire, there's fire. Mol Immunol. 2018;: pubmed publisher
    ..Here, we review the evidence for the immunoribosome hypothesis. ..