J C Yang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity
    J C Yang
    Surgery Branch, National Cancer Institute, Bethesda, MD 20892, USA
    J Clin Oncol 16:197-203. 1998
  2. ncbi Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b
    S A Rosenberg
    Surgery Branch and Department of Biostatistics and Data Management Section, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Oncol 17:968-75. 1999
  3. ncbi Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine
    S A Rosenberg
    Surgery Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 163:1690-5. 1999
  4. ncbi Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100
    Y Zhai
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Immunother 20:15-25. 1997
  5. ncbi High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    H J Zeh
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 162:989-94. 1999
  6. ncbi Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma
    M E Dudley
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1502, USA
    J Immunother 24:363-73. 2001
  7. ncbi Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas
    K Hanada
    Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 61:5511-6. 2001
  8. ncbi Serum endostatin levels are elevated in patients with soft tissue sarcoma
    A L Feldman
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer 91:1525-9. 2001
  9. ncbi Lack of retroperitoneal lymphadenopathy predicts survival of patients with metastatic renal cell carcinoma
    J R Vasselli
    Surgery Branch, Clinical Oncology Program, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Urol 166:68-72. 2001
  10. ncbi Immunization against endogenous retroviral tumor-associated antigens
    M H Kershaw
    Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 61:7920-4. 2001

Collaborators

Detail Information

Publications10

  1. ncbi Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity
    J C Yang
    Surgery Branch, National Cancer Institute, Bethesda, MD 20892, USA
    J Clin Oncol 16:197-203. 1998
    ..This randomized, prospective study assesses the impact of postoperative external-beam radiation therapy on local recurrence (LR), overall survival (OS), and quality of life after limb-sparing resection of extremity sarcomas...
  2. ncbi Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b
    S A Rosenberg
    Surgery Branch and Department of Biostatistics and Data Management Section, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Clin Oncol 17:968-75. 1999
    ..We have performed a prospective randomized trial in patients with metastatic melanoma, comparing treatment with chemotherapy to treatment with chemoimmunotherapy...
  3. ncbi Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine
    S A Rosenberg
    Surgery Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 163:1690-5. 1999
    ..These represent the first detailed studies of the impact of immunization with tumor peptides in conjunction with a variety of cytokines in patients with metastatic cancer...
  4. ncbi Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100
    Y Zhai
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Immunother 20:15-25. 1997
    ..These results may suggest that immunization with heterologous tumor antigen, rather than self, may be more effective as an immunotherapeutic reagent in designing antigen-specific cancer vaccines...
  5. ncbi High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    H J Zeh
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 162:989-94. 1999
    ..These results demonstrate that qualitative differences in the CTL that recognize these two self-Ags are critically important to their in vitro and in vivo anti-tumor efficacy...
  6. ncbi Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma
    M E Dudley
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1502, USA
    J Immunother 24:363-73. 2001
    ..The lack of clinical effectiveness of this protocol suggests that transfer of different or additional cell types or that modulation of the recipient host environment is required for successful therapy...
  7. ncbi Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas
    K Hanada
    Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 61:5511-6. 2001
    ..As a normal protein with significant overexpression by multiple adenocarcinomas and little normal tissue expression, FGF-5 represents an immunotherapy target with potential utility against a broad array of nonmelanoma cancers...
  8. ncbi Serum endostatin levels are elevated in patients with soft tissue sarcoma
    A L Feldman
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer 91:1525-9. 2001
    ..Elevated endostatin levels appear to be associated with tumor aggressiveness. The role of these cytokines in sarcoma angiogenesis and as potential targets for therapy warrants further study...
  9. ncbi Lack of retroperitoneal lymphadenopathy predicts survival of patients with metastatic renal cell carcinoma
    J R Vasselli
    Surgery Branch, Clinical Oncology Program, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Urol 166:68-72. 2001
    ....
  10. ncbi Immunization against endogenous retroviral tumor-associated antigens
    M H Kershaw
    Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 61:7920-4. 2001
    ..The ability to immunize against endogenous retroviral tumor antigens may have relevance in the induction of antitumor immunity for some human cancers...