Yuhe Yan

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892 0460, USA
    Retrovirology 5:2. 2008
  2. pmc Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 cell surface receptor
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Retrovirology 6:87. 2009
  3. pmc Evolution of functional and sequence variants of the mammalian XPR1 receptor for mouse xenotropic gammaretroviruses and the human-derived retrovirus XMRV
    Yuhe Yan
    NIH, NIAID, LMM, Bldg 4, Room 329, 4 Center Drive MSC 0460, Bethesda, MD 20892 0460
    J Virol 84:11970-80. 2010
  4. pmc Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage
    Ryan C Knoper
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Virology 391:232-9. 2009
  5. pmc Wild mouse variants of envelope genes of xenotropic/polytropic mouse gammaretroviruses and their XPR1 receptors elucidate receptor determinants of virus entry
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 0460, USA
    J Virol 81:10550-7. 2007
  6. pmc Origin, antiviral function and evidence for positive selection of the gammaretrovirus restriction gene Fv1 in the genus Mus
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Proc Natl Acad Sci U S A 106:3259-63. 2009
  7. pmc Rmcf2, a xenotropic provirus in the Asian mouse species Mus castaneus, blocks infection by polytropic mouse gammaretroviruses
    Tiyun Wu
    Laboratory of Molecular Microbiology, National Institute and Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    J Virol 79:9677-84. 2005
  8. pmc Novel postentry resistance to AKV ecotropic mouse gammaretroviruses in the African pygmy mouse, Mus minutoides
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 0460, USA
    J Virol 82:6120-9. 2008
  9. pmc Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove
    Bradley Sanville
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America
    PLoS Pathog 6:e1000974. 2010

Collaborators

Detail Information

Publications9

  1. pmc Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 20892 0460, USA
    Retrovirology 5:2. 2008
    ..Because M. dunni cells carry a variant CAT-1 cell surface virus receptor (dCAT-1), we examined the role of this receptor variant in cytopathicity and host range...
  2. pmc Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 cell surface receptor
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Retrovirology 6:87. 2009
    ..The mouse xenotropic/polytropic (X/PMV) gammaretroviruses rely on the XPR1 cell surface receptor for entry into host cells, and polymorphic variants of this receptor have been identified in different rodent species...
  3. pmc Evolution of functional and sequence variants of the mammalian XPR1 receptor for mouse xenotropic gammaretroviruses and the human-derived retrovirus XMRV
    Yuhe Yan
    NIH, NIAID, LMM, Bldg 4, Room 329, 4 Center Drive MSC 0460, Bethesda, MD 20892 0460
    J Virol 84:11970-80. 2010
    ....
  4. pmc Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage
    Ryan C Knoper
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Virology 391:232-9. 2009
    ..Virus envelope glycan size or type does not affect infectivity. Thus, host range variation due to N-glycan deletion is receptor variant-specific, cell-specific, virus type-specific, and glycan site-specific...
  5. pmc Wild mouse variants of envelope genes of xenotropic/polytropic mouse gammaretroviruses and their XPR1 receptors elucidate receptor determinants of virus entry
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 0460, USA
    J Virol 81:10550-7. 2007
    ....
  6. pmc Origin, antiviral function and evidence for positive selection of the gammaretrovirus restriction gene Fv1 in the genus Mus
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    Proc Natl Acad Sci U S A 106:3259-63. 2009
    ..This analysis suggests that Fv1 has had an antiviral role throughout Mus evolution predating exposure of mice to the MLVs restricted by laboratory mouse Fv1, and suggests a mechanism for Fv1 restriction...
  7. pmc Rmcf2, a xenotropic provirus in the Asian mouse species Mus castaneus, blocks infection by polytropic mouse gammaretroviruses
    Tiyun Wu
    Laboratory of Molecular Microbiology, National Institute and Allergy and Infectious Diseases, Bethesda, MD 20892 0460, USA
    J Virol 79:9677-84. 2005
    ..This type of provirus Env-mediated resistance represents an important defense mechanism in wild mouse populations exposed to endemic infections...
  8. pmc Novel postentry resistance to AKV ecotropic mouse gammaretroviruses in the African pygmy mouse, Mus minutoides
    Yuhe Yan
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 0460, USA
    J Virol 82:6120-9. 2008
    ..M. minutoides cells thus have a novel postentry resistance to AKV MLVs...
  9. pmc Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove
    Bradley Sanville
    Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America
    PLoS Pathog 6:e1000974. 2010
    ....