Zongli Xu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
    Li Qian
    Comprehensive Center for Inflammatory Disorders, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    J Neuroinflammation 4:23. 2007
  2. pmc SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Nucleic Acids Res 37:W600-5. 2009
  3. doi request reprint Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study
    Lisa A DeRoo
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Carcinogenesis 35:333-8. 2014
  4. pmc TAGster: efficient selection of LD tag SNPs in single or multiple populations
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Bioinformatics 23:3254-5. 2007
  5. pmc Epigenome-wide association study of breast cancer using prospectively collected sister study samples
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 105:694-700. 2013
  6. pmc No association between DNA repair gene XRCC1 and amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA
    Neurobiol Aging 33:1015.e25-6. 2012
  7. pmc GWAS SNP Replication among African American and European American men in the North Carolina-Louisiana prostate cancer project (PCaP)
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Prostate 71:881-91. 2011
  8. pmc Genome-wide analysis of loss of heterozygosity and copy number amplification in uterine leiomyomas using the 100K single nucleotide polymorphism array
    Kellen L Meadows
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Exp Mol Pathol 91:434-9. 2011
  9. pmc Inhibition of fried meat-induced colorectal DNA damage and altered systemic genotoxicity in humans by crucifera, chlorophyllin, and yogurt
    Daniel T Shaughnessy
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, United States of America
    PLoS ONE 6:e18707. 2011
  10. pmc Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced gammaH2A.X Foci
    Christina A Markunas
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    J Cancer Epidemiol 2008:387423. 2008

Collaborators

Detail Information

Publications11

  1. pmc Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
    Li Qian
    Comprehensive Center for Inflammatory Disorders, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    J Neuroinflammation 4:23. 2007
    ..Microglia-mediated inflammation has recently been implicated as a critical mechanism responsible for progressive neurodegeneration...
  2. pmc SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Nucleic Acids Res 37:W600-5. 2009
    ..Finally, we provide an example using prostate cancer and demonstrate that this algorithm can select a small panel of SNPs that include many of the recently validated prostate cancer SNPs...
  3. doi request reprint Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study
    Lisa A DeRoo
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Carcinogenesis 35:333-8. 2014
    ..PON1 (rs757158) was associated with breast cancer but not methylation. ..
  4. pmc TAGster: efficient selection of LD tag SNPs in single or multiple populations
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Bioinformatics 23:3254-5. 2007
    ..AVAILABILITY: The software Package TAGster is freely available at http://www.niehs.nih.gov/research/resources/software/tagster/..
  5. pmc Epigenome-wide association study of breast cancer using prospectively collected sister study samples
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 105:694-700. 2013
    ..Previous studies have suggested DNA methylation in blood is a potential epigenetic marker of cancer risk, but this has not been evaluated on a genome-wide scale in prospective studies for breast cancer...
  6. pmc No association between DNA repair gene XRCC1 and amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA
    Neurobiol Aging 33:1015.e25-6. 2012
    ..Our results did not show any differences in the frequency of XRCC1 gene polymorphisms between ALS patients and controls free of any neurological disease...
  7. pmc GWAS SNP Replication among African American and European American men in the North Carolina-Louisiana prostate cancer project (PCaP)
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Prostate 71:881-91. 2011
    ..This study evaluates GWAS SNPs associated with CaP in African Americans (AAs) and European Americans (EA)...
  8. pmc Genome-wide analysis of loss of heterozygosity and copy number amplification in uterine leiomyomas using the 100K single nucleotide polymorphism array
    Kellen L Meadows
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Exp Mol Pathol 91:434-9. 2011
    ..Despite the importance of this tumor in women's health, relatively little is known about the molecular etiology...
  9. pmc Inhibition of fried meat-induced colorectal DNA damage and altered systemic genotoxicity in humans by crucifera, chlorophyllin, and yogurt
    Daniel T Shaughnessy
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, United States of America
    PLoS ONE 6:e18707. 2011
    ..To our knowledge, this is the first demonstration that dietary factors can reduce DNA damage in the target tissue of fried-meat associated carcinogenesis...
  10. pmc Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced gammaH2A.X Foci
    Christina A Markunas
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    J Cancer Epidemiol 2008:387423. 2008
    ..We saw no significant difference in gammaH2A.X foci between controls and any of the panels of cell lines representing the different nsSNPs...
  11. ncbi request reprint Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data
    Zongli Xu
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Eur J Hum Genet 15:1063-70. 2007
    ..Finally, we generalized the greedy algorithm proposed by Carlson et al (2004) to select tag SNPs for multiple populations and implemented the algorithm into a freely available software package mPopTag...