Renee Wong

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Cardioprotection leads to novel changes in the mitochondrial proteome
    Renee Wong
    Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 298:H75-91. 2010
  2. doi request reprint Cyclophilin D modulates mitochondrial acetylome
    Tiffany Tuyen M Nguyen
    From the Systems Biology Center T T M N, S M, J S, E M, Division of Cardiovascular Sciences R W, Proteomics Core Facility Y C, G W, M G, and Center for Molecular Medicine M N S, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD and Department of Pathology, Johns Hopkins Medical Center, Baltimore, MD C S
    Circ Res 113:1308-19. 2013
  3. pmc CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism
    Sara Menazza
    Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    J Mol Cell Cardiol 56:81-90. 2013
  4. pmc Acute inhibition of GSK causes mitochondrial remodeling
    Tiffany Nguyen
    Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Am J Physiol Heart Circ Physiol 302:H2439-45. 2012
  5. doi request reprint The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
    Nisha Narayan
    Center for Molecular Medicine, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland 20892, USA
    Nature 492:199-204. 2012
  6. pmc Mechanism of cardioprotection: what can we learn from females?
    Elizabeth Murphy
    NHLBI, NIH, Room 8N202, Building 10, 10 Center Drive, Bethesda, MD, USA
    Pediatr Cardiol 32:354-9. 2011
  7. pmc Mitochondrial permeability transition pore and calcium handling
    Renee Wong
    Cardiac Physiology Section, Systems Biology Center, NHLBI, NIH, Bethesda, MD 20892, USA
    Methods Mol Biol 810:235-42. 2012

Collaborators

Detail Information

Publications7

  1. pmc Cardioprotection leads to novel changes in the mitochondrial proteome
    Renee Wong
    Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 298:H75-91. 2010
    ..Thus the ability of PC and GSK inhibition to alter the expression levels of electron transport complexes will have important implications for mitochondrial function...
  2. doi request reprint Cyclophilin D modulates mitochondrial acetylome
    Tiffany Tuyen M Nguyen
    From the Systems Biology Center T T M N, S M, J S, E M, Division of Cardiovascular Sciences R W, Proteomics Core Facility Y C, G W, M G, and Center for Molecular Medicine M N S, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD and Department of Pathology, Johns Hopkins Medical Center, Baltimore, MD C S
    Circ Res 113:1308-19. 2013
    ..As acetylation has been shown to regulate metabolism, we tested whether changes in protein acetylation might play a role in these metabolic changes in CypD(-/-) hearts...
  3. pmc CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism
    Sara Menazza
    Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    J Mol Cell Cardiol 56:81-90. 2013
    ..In summary, CypD(-/-) hearts exhibit changes in many metabolic pathways and caution should be used when interpreting results from these mice as due solely to inhibition of the MPTP...
  4. pmc Acute inhibition of GSK causes mitochondrial remodeling
    Tiffany Nguyen
    Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Am J Physiol Heart Circ Physiol 302:H2439-45. 2012
    ..Taken together, these data show that SB leads to a remodeling of the mitochondrial proteome that is partially GD sensitive...
  5. doi request reprint The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
    Nisha Narayan
    Center for Molecular Medicine, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland 20892, USA
    Nature 492:199-204. 2012
    ....
  6. pmc Mechanism of cardioprotection: what can we learn from females?
    Elizabeth Murphy
    NHLBI, NIH, Room 8N202, Building 10, 10 Center Drive, Bethesda, MD, USA
    Pediatr Cardiol 32:354-9. 2011
    ..It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed...
  7. pmc Mitochondrial permeability transition pore and calcium handling
    Renee Wong
    Cardiac Physiology Section, Systems Biology Center, NHLBI, NIH, Bethesda, MD 20892, USA
    Methods Mol Biol 810:235-42. 2012
    ..This chapter focuses on key issues in the study of the MPT and provides some methods for measuring MPT opening in isolated mitochondria...