L Wolff


Affiliation: National Institutes of Health
Country: USA


  1. request reprint
    Wolff L. Myb-induced transformation. Crit Rev Oncog. 1996;7:245-60 pubmed
    ..Although c-myb's involvement in human leukemia has been suggested, it has never been clearly established and should be investigated further. ..
  2. Wolff L, Koller R, Hu X, Anver M. A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms. J Virol. 2003;77:4965-71 pubmed
    ..Interesting, MCF recombinant envelope was expressed in the lymphoid but not the myeloid neoplasms of BALB/c mice. This retrovirus has the potential for accelerating myeloid disease in genetically engineered mice...
  3. request reprint
    Wolff L, Garin M, Koller R, Bies J, Liao W, Malumbres M, et al. Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice. Oncogene. 2003;22:9265-74 pubmed
    ..Mice deficient in both alleles were not more susceptible to myeloid disease than those deficient in one allele, raising the possibility that there are opposing forces related to the development of myeloid leukemia in Ink4b null mice. ..
  4. request reprint
    Wolff L, Garin M, Koller R, Bies J, Tessarollo L, Anver M, et al. A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15Ink4b in myeloid cells in vivo. Blood Cells Mol Dis. 2004;32:226-31 pubmed