Robert Wojciechowski

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Hum Genet 119:389-99. 2006
  2. pmc Dissecting the genetic heterogeneity of myopia susceptibility in an Ashkenazi Jewish population using ordered subset analysis
    Claire L Simpson
    1nherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Vis 17:1641-51. 2011
  3. pmc Genomewide linkage scans for ocular refraction and meta-analysis of four populations in the Myopia Family Study
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, Baltimore, Maryland 21231, USA
    Invest Ophthalmol Vis Sci 50:2024-32. 2009
  4. pmc Matrix metalloproteinases and educational attainment in refractive error: evidence of gene-environment interactions in the Age-Related Eye Disease Study
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Ophthalmology 120:298-305. 2013
  5. pmc Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland 21224, USA
    Invest Ophthalmol Vis Sci 51:4989-95. 2010
  6. pmc Regional replication of association with refractive error on 15q14 and 15q25 in the Age-Related Eye Disease Study cohort
    Claire L Simpson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD
    Mol Vis 19:2173-86. 2013
  7. pmc Fine-mapping of candidate region in Amish and Ashkenazi families confirms linkage of refractive error to a QTL on 1p34-p36
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, 333 Cassell Drive, Baltimore, MD 21224, USA
    Mol Vis 15:1398-406. 2009
  8. pmc Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects
    Yoonhee Kim
    National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA
    BMC Proc 3:S64. 2009
  9. pmc Old lessons learned anew: family-based methods for detecting genes responsible for quantitative and qualitative traits in the Genetic Analysis Workshop 17 mini-exome sequence data
    Claire L Simpson
    Statistical Genetics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 31 Center Drive, 333 Cassell Drive Suite 1200, Baltimore, MD 21224, USA
    BMC Proc 5:S83. 2011
  10. pmc Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits
    Alison P Klein
    Inherited Disease Research Branch, NHGRI NIH, Baltimore, MD, USA
    BMC Genet 6:S20. 2005

Collaborators

Detail Information

Publications10

  1. pmc Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Hum Genet 119:389-99. 2006
    ..Conclusion: We found genomewide significant evidence for linkage of refractive error to a novel QTL on chromosome 1p36 in an Ashkenazi Jewish population...
  2. pmc Dissecting the genetic heterogeneity of myopia susceptibility in an Ashkenazi Jewish population using ordered subset analysis
    Claire L Simpson
    1nherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Vis 17:1641-51. 2011
    ..Genetic studies have pointed to a strong inherited component, but although many candidate regions have been implicated, few genes have been positively identified...
  3. pmc Genomewide linkage scans for ocular refraction and meta-analysis of four populations in the Myopia Family Study
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, Baltimore, Maryland 21231, USA
    Invest Ophthalmol Vis Sci 50:2024-32. 2009
    ..We also performed a meta-analysis by combining these results with our previous linkage results from Ashkenazi Jewish (ASHK) and African American (AFRAM) families...
  4. pmc Matrix metalloproteinases and educational attainment in refractive error: evidence of gene-environment interactions in the Age-Related Eye Disease Study
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Ophthalmology 120:298-305. 2013
    ..A candidate gene replication study of association between refraction and single nucleotide polymorphisms (SNPs) within these genomic regions was conducted...
  5. pmc Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland 21224, USA
    Invest Ophthalmol Vis Sci 51:4989-95. 2010
    ..The genetic association of refractive error and polymorphisms in MMP and TIMP genes in Old Order Amish (AMISH) and Ashkenazi Jewish (ASHK) families was investigated...
  6. pmc Regional replication of association with refractive error on 15q14 and 15q25 in the Age-Related Eye Disease Study cohort
    Claire L Simpson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD
    Mol Vis 19:2173-86. 2013
    ..This paper seeks to determine whether the non-replication in this AREDS sample may be due to the limited number of SNPs chosen for replication...
  7. pmc Fine-mapping of candidate region in Amish and Ashkenazi families confirms linkage of refractive error to a QTL on 1p34-p36
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, 333 Cassell Drive, Baltimore, MD 21224, USA
    Mol Vis 15:1398-406. 2009
    ..1. We carried out a fine-mapping study of this region in Orthodox Ashkenazi Jewish (ASHK) and Old Order Amish (OOA) families to confirm linkage and narrow the candidate region...
  8. pmc Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects
    Yoonhee Kim
    National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA
    BMC Proc 3:S64. 2009
    ....
  9. pmc Old lessons learned anew: family-based methods for detecting genes responsible for quantitative and qualitative traits in the Genetic Analysis Workshop 17 mini-exome sequence data
    Claire L Simpson
    Statistical Genetics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 31 Center Drive, 333 Cassell Drive Suite 1200, Baltimore, MD 21224, USA
    BMC Proc 5:S83. 2011
    ..The family-based tests of association found the same major loci as the linkage analyses and detected low-frequency loci with moderate effect sizes, but control of type I error was not as stringent...
  10. pmc Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits
    Alison P Klein
    Inherited Disease Research Branch, NHGRI NIH, Baltimore, MD, USA
    BMC Genet 6:S20. 2005
    ..The presence of LD between markers may have led to an increased number of false positive regions but no clear relationship between regions of high LD and locations of false positive linkage signals was observed...