G Winterer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Schizophrenia: reduced signal-to-noise ratio and impaired phase-locking during information processing
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, 10 Center Drive, Room 4S235 MSC 1379, Bethesda, USA
    Clin Neurophysiol 111:837-49. 2000
  2. ncbi request reprint Genetics of human prefrontal function
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res Brain Res Rev 43:134-63. 2003
  3. ncbi request reprint Association of EEG coherence and an exonic GABA(B)R1 gene polymorphism
    Georg Winterer
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:51-6. 2003
  4. ncbi request reprint An association between reduced interhemispheric EEG coherence in the temporal lobe and genetic risk for schizophrenia
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1379, USA
    Schizophr Res 49:129-43. 2001
  5. ncbi request reprint Prefrontal broadband noise, working memory, and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Am J Psychiatry 161:490-500. 2004
  6. ncbi request reprint Association analysis of exonic variants of the GABA(B)-receptor gene and alpha electroencephalogram voltage in normal subjects and alcohol-dependent patients
    Georg Winterer
    Department of Psychiatry, Benjamin Franklin University Hospital, Free University of Berlin, Berlin, Germany
    Behav Genet 33:7-15. 2003
  7. ncbi request reprint EEG phenotype in alcoholism: increased coherence in the depressive subtype
    G Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Acta Psychiatr Scand 108:51-60. 2003
  8. ncbi request reprint Association analysis of GABAAbeta2 and gamma2 gene polymorphisms with event-related prefrontal activity in man
    G Winterer
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Germany
    Hum Genet 107:513-8. 2000
  9. ncbi request reprint Frontal dysfunction in schizophrenia--a new electrophysiological classifier for research and clinical applications
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Eur Arch Psychiatry Clin Neurosci 250:207-14. 2000
  10. ncbi request reprint P300 and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4s229A, MSC 1379, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 60:1158-67. 2003

Detail Information

Publications60

  1. ncbi request reprint Schizophrenia: reduced signal-to-noise ratio and impaired phase-locking during information processing
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, 10 Center Drive, Room 4S235 MSC 1379, Bethesda, USA
    Clin Neurophysiol 111:837-49. 2000
    ....
  2. ncbi request reprint Genetics of human prefrontal function
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res Brain Res Rev 43:134-63. 2003
    ..Special emphasis is also given to methodological concerns that need to be addressed when conducting research on the genetics of prefrontal function in humans...
  3. ncbi request reprint Association of EEG coherence and an exonic GABA(B)R1 gene polymorphism
    Georg Winterer
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:51-6. 2003
    ..Since variations of EEG coherence have been described for several neuropsychiatric disorders, the present association should be tested in clinical samples using EEG coherence as an intermediate phenotype...
  4. ncbi request reprint An association between reduced interhemispheric EEG coherence in the temporal lobe and genetic risk for schizophrenia
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1379, USA
    Schizophr Res 49:129-43. 2001
    ..Thus, while power spectrum EEG abnormalities may be state-dependent, reduced coherence as a possible measure of neuronal synchronization is familial and potentially a heritable trait related to genetic risk for schizophrenia...
  5. ncbi request reprint Prefrontal broadband noise, working memory, and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Am J Psychiatry 161:490-500. 2004
    ..In the present study, the authors explored whether this particular physiological abnormality predicts working memory performance and is related to the genetic risk for schizophrenia...
  6. ncbi request reprint Association analysis of exonic variants of the GABA(B)-receptor gene and alpha electroencephalogram voltage in normal subjects and alcohol-dependent patients
    Georg Winterer
    Department of Psychiatry, Benjamin Franklin University Hospital, Free University of Berlin, Berlin, Germany
    Behav Genet 33:7-15. 2003
    ....
  7. ncbi request reprint EEG phenotype in alcoholism: increased coherence in the depressive subtype
    G Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Acta Psychiatr Scand 108:51-60. 2003
    ..However, it is unclear whether alpha power and coherence differences reflect reversible toxic or withdrawal effects of alcohol...
  8. ncbi request reprint Association analysis of GABAAbeta2 and gamma2 gene polymorphisms with event-related prefrontal activity in man
    G Winterer
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Germany
    Hum Genet 107:513-8. 2000
    ....
  9. ncbi request reprint Frontal dysfunction in schizophrenia--a new electrophysiological classifier for research and clinical applications
    G Winterer
    Clinical Brain Disorder Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Eur Arch Psychiatry Clin Neurosci 250:207-14. 2000
    ..It is proposed that this new classifier can be useful for clinical and research applications when subtyping of schizophrenics with detection of frontal dysfunction as the aim...
  10. ncbi request reprint P300 and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4s229A, MSC 1379, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 60:1158-67. 2003
    ....
  11. doi request reprint Brain activation patterns underlying fast habituation to painful laser stimuli
    A Mobascher
    Neuropsychiatric Research Laboratory, Department of Psychiatry, Heinrich Heine University Duesseldorf, Germany
    Int J Psychophysiol 75:16-24. 2010
    ....
  12. doi request reprint Fluctuations in electrodermal activity reveal variations in single trial brain responses to painful laser stimuli--a fMRI/EEG study
    A Mobascher
    Department of Psychiatry, Neuropsychiatric Research Laboratory, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 44:1081-92. 2009
    ..Thus, EDA is a useful additional, objective index when pain is studied with fMRI/EEG which might be of particular relevance in the context of genetic- and pharmacoimaging...
  13. ncbi request reprint Reduced event-related current density in the anterior cingulate cortex in schizophrenia
    C Mulert
    Laboratory for Clinical Psychophysiology, Free University, Berlin, Germany
    Neuroimage 13:589-600. 2001
    ..Our data also suggest that anterior cingulate function in schizophrenics is disturbed at a relatively early time point in the information-processing stream (100-140 ms poststimulus)...
  14. ncbi request reprint Cortical activation, signal-to-noise ratio and stochastic resonance during information processing in man
    G Winterer
    Department of Psychiatry, Free University of Berlin, Germany
    Clin Neurophysiol 110:1193-203. 1999
    ....
  15. doi request reprint Distinct haplogenotypes of the dopamine D2 receptor gene are associated with non-smoking behaviour and daily cigarette consumption
    C Wernicke
    Charite Universitatsmedizin Berlin, Klinische Neurobiologie, Klinik für Psychiatrie and Psychotherapie, Campus Benjamin Franklin, Berlin, Germany
    Pharmacopsychiatry 42:41-50. 2009
    ..Thus, the knowledge about the distribution of the haplotypes in groups of subjects, differing by their smoking behaviour, would result in a better understanding of the putative associations compared to single SNP investigations...
  16. ncbi request reprint P300 and LORETA: comparison of normal subjects and schizophrenic patients
    G Winterer
    Department of Psychiatry, Free University Berlin, Germany
    Brain Topogr 13:299-313. 2001
    ..The data further suggest that the P300-deficit in schizophrenics involves an extended cortical network of the left hemisphere at several steps in time during the information processing stream...
  17. ncbi request reprint Genetic variation of the glutamate transporter EAAT2 gene and vulnerability to alcohol dependence
    T Sander
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Germany
    Psychiatr Genet 10:103-7. 2000
    ..009). These two consistent lines of evidence suggest that genetic variation of the EAAT2 gene confers vulnerability to risk-taking behavior in alcoholics...
  18. doi request reprint Laser-evoked potential P2 single-trial amplitudes covary with the fMRI BOLD response in the medial pain system and interconnected subcortical structures
    A Mobascher
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 45:917-26. 2009
    ..Furthermore, our findings suggest a concerted effort of the ACC and the amygdala in the cognitive-emotional evaluation of pain...
  19. ncbi request reprint Association analysis between a Cys23Ser substitution polymorphism of the human 5-HT2c receptor gene and neuronal hyperexcitability
    J Samochowiec
    Department of Psychiatry, University Hospital Benjamin Franklin, Free University of Berlin, Germany
    Am J Med Genet 88:126-30. 1999
    ....
  20. ncbi request reprint Evaluation of an allelic association of the serotonin 5-HT1B G681C polymorphism with antisocial alcoholism in the German population
    T Sander
    Department of Psychiatry, University Hospital Charite, Campus Virchow Clinic, Humboldt University of Berlin, Berlin, Germany
    Addict Biol 5:167-72. 2000
    ..52). Our results do not provide evidence that the 861C allele contributes a substantial vulnerability effect to antisocial behavior in German alcohol-dependent subjects...
  21. ncbi request reprint Spontaneous brain activity and EEG microstates. A novel EEG/fMRI analysis approach to explore resting-state networks
    F Musso
    Department of Psychiatry, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
    Neuroimage 52:1149-61. 2010
    ....
  22. ncbi request reprint Event-related potentials and genetic risk for schizophrenia
    G Winterer
    Clinical Brain Disorders Branch, NIMH/NIH, Building 10, Room 4S229A MSC, Bethesda, MD 20892, USA
    Biol Psychiatry 50:407-17. 2001
    ..Possible reasons for these largely negative findings are discussed...
  23. pmc Hippocampal subfields predict positive symptoms in schizophrenia: first evidence from brain morphometry
    S Kuhn
    Charite University Medicine, St Hedwig Krankenhaus, Clinic for Psychiatry and Psychotherapy, Berlin, Germany
    Transl Psychiatry 2:e127. 2012
    ..Our observation opens the gate for advanced investigation of the commonly reported hippocampal abnormalities in schizophrenia in terms of specific subfields...
  24. doi request reprint Association of a variant in the muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction
    A Mobascher
    Department of Psychiatry, Neuropsychiatric Research Laboratory, Heinrich Heine University, Duesseldorf, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:684-90. 2010
    ..Alternatively, variations in CHRM2 could modulate presynaptic auto-regulation in cholinergic systems and may thereby affect an individual's response to nicotine more specifically...
  25. ncbi request reprint Cortical microcircuits in schizophrenia--the dopamine hypothesis revisited
    G Winterer
    Department of Psychiatry, Heinrich Heine University Hospital Duesseldorf, Germany
    Pharmacopsychiatry 39:S68-71. 2006
    ..In schizophrenia, a diminished cortical dopamine D1/D2 activation ratio--in concert with altered GABAergic and glutamatergic transmission--appear to critically interfere with this process...
  26. ncbi request reprint Single-trial P3 amplitude and latency informed event-related fMRI models yield different BOLD response patterns to a target detection task
    T Warbrick
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 47:1532-44. 2009
    ..Our findings suggest that ERP amplitudes and latencies can yield different activation patterns when used to modify relevant aspects of the GLM...
  27. ncbi request reprint Electrophysiological subtypes of psychotic states
    E R John
    Brain Research Laboratories, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Acta Psychiatr Scand 116:17-35. 2007
    ..This research sought neurobiological features common to psychotic states displayed by patients with different clinical diagnoses...
  28. doi request reprint The P300 event-related potential and smoking--a population-based case-control study
    A Mobascher
    Neuropsychiatric Research Laboratory, Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Int J Psychophysiol 77:166-75. 2010
    ..Our results provide the phenotypical groundwork for future multidimensional analyses of genotype-phenotype relationships in the field of smoking and nicotine dependence...
  29. ncbi request reprint Hypofrontality -- a risk-marker related to schizophrenia?
    Y Wuebben
    Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany
    Schizophr Res 48:207-17. 2001
    ..However, since it is controversial whether subjects with schizotypal personality are at increased risk for schizophrenia, further studies in unaffected family members of schizophrenic patients are needed...
  30. doi request reprint The molecular and cellular neurobiology of nicotine abuse in schizophrenia
    A Mobascher
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Pharmacopsychiatry 41:S51-9. 2008
    ....
  31. ncbi request reprint Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans
    Jurgen Gallinat
    Klinik für Psychiatrie and Psychotherapie, Charite Universitatsmedizin, Berlin
    J Cogn Neurosci 19:59-68. 2007
    ..Because the NR3A is expressed in the human prefrontal cortex, we hypothesized that genetic variations of the NR3A subunit modulate prefrontal activation...
  32. ncbi request reprint Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking
    Undine E Lang
    Department of Psychiatry and Psychotherapy, University of Dresden, Fetscherstr 74, 01307, Dresden, Germany
    Psychopharmacology (Berl) 190:433-9. 2007
    ..In this study, we addressed the question if a common BDNF missense variation (Val66Met) influences the risk for smoking behavior in otherwise healthy human volunteers...
  33. ncbi request reprint Frontal and temporal dysfunction of auditory stimulus processing in schizophrenia
    Jurgen Gallinat
    Department of Psychiatry, Free University, Berlin, Germany
    Neuroimage 17:110-27. 2002
    ..This would be in line with the notion that attention deficits in schizophrenia involve an extended cortical network...
  34. ncbi request reprint Association of attentional network function with exon 5 variations of the CHRNA4 gene
    Georg Winterer
    Department of Psychiatry, Henirich Heine University, Duesseldorf, Germany
    Hum Mol Genet 16:2165-74. 2007
    ..If confirmed, future studies need to address what 'functional' polymorphisms are causative for the observed effects...
  35. pmc Neurophysiological biomarkers for drug development in schizophrenia
    Daniel C Javitt
    Nathan Kline Institute for Schizophrenia Research New York University School of Medicine, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA
    Nat Rev Drug Discov 7:68-83. 2008
    ..Moreover, many of these neurophysiological processes are phylogenetically conserved and can be modelled in preclinical studies, offering unique opportunities for use as translational biomarkers in schizophrenia drug discovery...
  36. ncbi request reprint Cortical hypoactivation during resting EEG in schizophrenics but not in depressives and schizotypal subjects as revealed by low resolution electromagnetic tomography (LORETA)
    Susanne Mientus
    Department of Psychiatry, Free University of Berlin, Berlin, Germany
    Psychiatry Res 116:95-111. 2002
    ..The results are discussed within a neurophysiological and methodological framework...
  37. ncbi request reprint Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population
    Catrin Wernicke
    Department of Clinical Neurobiology, Benjamin Franklin Medical School, Free University of Berlin, Ulmenallee 32, D 14050 Berlin, Germany
    Neurosci Lett 333:45-8. 2002
    ..032, OR = 4.707), and with an alcoholic mother (P = 0.021, OR = 5.250), compared to homozygote 10/10 controls. Our findings provide further evidence that the 3'UTR of the DAT1 gene affects vulnerability to severe alcohol withdrawal...
  38. ncbi request reprint Association of elevated phospho-tau levels with Alzheimer-typical 18F-fluoro-2-deoxy-D-glucose positron emission tomography findings in patients with mild cognitive impairment
    Andreas Fellgiebel
    Department of Psychiatry, University of Mainz, Mainz, Germany
    Biol Psychiatry 56:279-83. 2004
    ....
  39. ncbi request reprint Volition to action--an event-related fMRI study
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuroimage 17:851-8. 2002
    ..These results are in line with our previous electrophysiological findings and provide further evidence that early ACC activation during a choice reaction task reflects the intentional effort of a subject to carry out a task...
  40. ncbi request reprint Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series
    Stefano Marenco
    Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Building 10, Room 4S235, Bethesda, MD 20892, USA
    Schizophr Res 57:221-6. 2002
    ..No clear improvement in psychosis or in cognition was observed over the course of the study. CX516 at the doses tested did not appear to yield dramatic effects as a sole agent, but inference from this study is limited...
  41. ncbi request reprint Complex relationship between BOLD signal and synchronization/desynchronization of human brain MEG oscillations
    Georg Winterer
    MEG Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, USA
    Hum Brain Mapp 28:805-16. 2007
    ....
  42. ncbi request reprint Instability of prefrontal signal processing in schizophrenia
    Georg Winterer
    Genes, Cognition and Psychosis Program, NIH, NIMH, 10 Center Dr, MSC 1379, Bethesda, MD 20892, USA
    Am J Psychiatry 163:1960-8. 2006
    ....
  43. ncbi request reprint Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing
    Jurgen Gallinat
    Laboratory for Clinical Psychophysiology, Department of Psychiatry, Free University, Berlin, Germany and National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 54:40-8. 2003
    ..It was predicted that homozygous Met allele carriers have a lower frontal P300 amplitude...
  44. ncbi request reprint Functional and effective frontotemporal connectivity and genetic risk for schizophrenia
    Georg Winterer
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Biol Psychiatry 54:1181-92. 2003
    ..We sought to determine whether abnormalities of frontotemporal connectivity are trait markers of genetic risk for schizophrenia...
  45. ncbi request reprint Allelic variants of the functional promoter polymorphism of the human serotonin transporter gene is associated with auditory cortical stimulus processing
    Jurgen Gallinat
    Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany
    Neuropsychopharmacology 28:530-2. 2003
    ..The LD may serve as endophenotype in human serotonin research...
  46. ncbi request reprint Reduced oscillatory gamma-band responses in unmedicated schizophrenic patients indicate impaired frontal network processing
    Jurgen Gallinat
    Clinic for Psychiatry and Psychotherapy, Humboldt University, Berlin, Germany
    Clin Neurophysiol 115:1863-74. 2004
    ..This is the first investigation of oscillatory activations in the gamma-band in an auditory oddball paradigm in unmedicated schizophrenic patients...
  47. ncbi request reprint The relationship between reaction time, error rate and anterior cingulate cortex activity
    Christoph Mulert
    Laboratory for Clinical Psychophysiology, Department of Psychiatry, Free University, Berlin, Germany
    Int J Psychophysiol 47:175-83. 2003
    ..This finding suggests that increased ACC activity is associated with a gain in reaction speed at the expense of correctness and is discussed in the context of current concepts about the role of the ACC in cognitive functions...
  48. ncbi request reprint Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits
    Catrin Wernicke
    Department of Clinical Neurobiology, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Biol Psychiatry 54:922-8. 2003
    ..This study examined the hypothesis that allelic variants of the ionotropic glutamatergic N-methyl-D-aspartate receptor (NMDAR) are associated with vulnerability to alcoholism and some related traits...
  49. ncbi request reprint Distributed BOLD-response in association cortex vector state space predicts reaction time during selective attention
    Francesco Musso
    Laboratory of Molecular Neuroimaging and Electrophysiology, Department of Psychiatry, Johannes Gutenberg University Hospital, Untere Zahlbacherstr 8, 55131 Mainz, Germany
    Neuroimage 29:1311-8. 2006
    ....
  50. ncbi request reprint Smoking impacts on prefrontal attentional network function in young adult brains
    Francesco Musso
    Department of Psychiatry, Heinrich Heine University, Bergische Landstr 2, 40629 Duesseldorf, Germany
    Psychopharmacology (Berl) 191:159-69. 2007
    ..In contrast, little is known about potentially neurotoxic effects on the attentional network during neurodevelopmentally critical periods, such as during adolescence and early adulthood...
  51. ncbi request reprint Persistent dysfunctional frontal lobe activation in former smokers
    Andres Neuhaus
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Benjamin Franklin, Berlin, Germany
    Psychopharmacology (Berl) 186:191-200. 2006
    ..However, it is largely unknown if cerebral dysfunctions are reversible or persist during long term abstinence...
  52. ncbi request reprint Prefrontal electrophysiologic "noise" and catechol-O-methyltransferase genotype in schizophrenia
    Georg Winterer
    Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 60:578-84. 2006
    ....
  53. ncbi request reprint COMT genotype predicts BOLD signal and noise characteristics in prefrontal circuits
    Georg Winterer
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 32:1722-32. 2006
    ..In the present study, we addressed the question of whether the prefrontal SNR of the BOLD response is decreased in Val carriers using a visual oddball task and an approach to analysis of fMRI data that maximizes noise characterization...
  54. doi request reprint Association of 5' end neuregulin-1 (NRG1) gene variation with subcortical medial frontal microstructure in humans
    Georg Winterer
    Department of Psychiatry, Heinrich Heine University, Bergische Landstr 2, 40629 Duesseldorf, Germany
    Neuroimage 40:712-8. 2008
    ..By extension, our findings suggest that SNP8NRG221533 may contribute to the risk for the complex polygenic illness schizophrenia via its impact on myelination in frontal lobe white matter...
  55. ncbi request reprint Valproate and GABAergic system effects
    Georg Winterer
    Neuropsychopharmacology 28:2050-1. 2003
  56. pmc Disturbed structural connectivity in schizophrenia primary factor in pathology or epiphenomenon?
    Andreas Konrad
    Department of Psychiatry, Johannes Gutenberg University, Mainz, Germany
    Schizophr Bull 34:72-92. 2008
    ....
  57. ncbi request reprint Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study
    Andreas Fellgiebel
    Department of Psychiatry, University of Mainz, Mainz, Germany
    Dement Geriatr Cogn Disord 18:101-8. 2004
    ..4% (with a specificity set at 80%). Therefore, the DTI technique validates the MCI concept, and diffusion tensor MR measurement can be a helpful tool to quantify MCI pathology in vivo...
  58. ncbi request reprint Genes, dopamine and cortical signal-to-noise ratio in schizophrenia
    Georg Winterer
    Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Trends Neurosci 27:683-90. 2004
    ..In schizophrenia, an abnormal cortical dopamine D1/D2 activation ratio - in concert with, and in part related to, altered GABA and glutamate transmission - appears to interfere crucially with this process...
  59. ncbi request reprint Neuroimaging and human genetics
    Georg Winterer
    Genes, Cognition and Psychosis Program, National Institute of Mental Health National Institutes of Health, Bethesda, Maryland 20892, USA
    Int Rev Neurobiol 67:325-83. 2005
  60. ncbi request reprint EEG microstate duration and syntax in acute, medication-naive, first-episode schizophrenia: a multi-center study
    Dietrich Lehmann
    The KEY Institute for Brain Mind Research, University Hospital of Psychiatry, CH 8029 Zurich, Switzerland
    Psychiatry Res 138:141-56. 2005
    ..The intermittent occurrence might account for Bleuler's "double bookkeeping." The disturbed microstate syntax opens a novel physiological comparison of mental operations between patients and controls...