Denise Whitby

Summary

Affiliation: National Cancer Institute
Country: USA

Publications

  1. ncbi request reprint Genotypic characterization of Kaposi's sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, NCI Frederick, MD 21701, USA
    J Gen Virol 85:155-63. 2004
  2. pmc Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, NCI Frederick, Frederick, MD 21702, USA
    Int J Cancer 120:321-8. 2007
  3. pmc Sequence analysis of Kaposi sarcoma-associated herpesvirus (KSHV) microRNAs in patients with multicentric Castleman disease and KSHV-associated inflammatory cytokine syndrome
    Alex Ray
    National Cancer Institute, Frederick, MD, USA
    J Infect Dis 205:1665-76. 2012
  4. pmc Kaposi sarcoma (KS)-associated herpesvirus microRNA sequence analysis and KS risk in a European AIDS-KS case control study
    Vickie Marshall
    Viral Oncology Section, SAIC Frederick, NCI Frederick, Frederick, Maryland 21702, USA
    J Infect Dis 202:1126-35. 2010
  5. pmc An interleukin-6-related systemic inflammatory syndrome in patients co-infected with Kaposi sarcoma-associated herpesvirus and HIV but without Multicentric Castleman disease
    Thomas S Uldrick
    HIV and AIDS Malignancy Branch, National Cancer Institute Frederick, Frederick, MD, USA
    Clin Infect Dis 51:350-8. 2010
  6. pmc Detection of antibodies to Kaposi's sarcoma-associated herpesvirus: a new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA
    Georgina L Mbisa
    Viral Technology Laboratory, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, United States
    J Immunol Methods 356:39-46. 2010
  7. doi request reprint Kaposi's sarcoma-associated herpesvirus transmission and primary infection
    Rachel Bagni
    Viral Oncology Section, AIDS and Cancer Virus Program, SAIC Frederick, NCI Frederick, Frederick, Maryland 21702, USA
    Curr Opin HIV AIDS 4:22-6. 2009
  8. ncbi request reprint Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman disease
    Vickie Marshall
    Viral Epidemiology Section, AIDS Vaccine Program, Science Applications International Corporation Frederick, National Cancer Institute Frederick, Frederick, MD 21701, USA
    J Infect Dis 195:645-59. 2007
  9. pmc Risk factors for seropositivity to Kaposi sarcoma-associated herpesvirus among children in Uganda
    Katie Wakeham
    Medical Research Council, Uganda Virus Research Institute, Uganda Research Unit on AIDS, Entebbe, Uganda
    J Acquir Immune Defic Syndr 63:228-33. 2013
  10. pmc Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, National Cancer Institute, Frederick, MD 21702, USA
    J Virol 77:8159-65. 2003

Detail Information

Publications54

  1. ncbi request reprint Genotypic characterization of Kaposi's sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, NCI Frederick, MD 21701, USA
    J Gen Virol 85:155-63. 2004
    ..The heterogeneity of the KSHV strains found in these subjects from Botswana contrasts with the homogeneity of KSHV strains in Amerindians, reflecting differences in the evolutionary history of these populations...
  2. pmc Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, NCI Frederick, Frederick, MD 21702, USA
    Int J Cancer 120:321-8. 2007
    ..These in vitro data provide support for the "oncoweed" hypothesis by demonstrating basic biological plausibility...
  3. pmc Sequence analysis of Kaposi sarcoma-associated herpesvirus (KSHV) microRNAs in patients with multicentric Castleman disease and KSHV-associated inflammatory cytokine syndrome
    Alex Ray
    National Cancer Institute, Frederick, MD, USA
    J Infect Dis 205:1665-76. 2012
    ..We observed a high level of conservation for most sequences but also a divergent cluster of 5 KSHV sequences, including 2 from MCD patients...
  4. pmc Kaposi sarcoma (KS)-associated herpesvirus microRNA sequence analysis and KS risk in a European AIDS-KS case control study
    Vickie Marshall
    Viral Oncology Section, SAIC Frederick, NCI Frederick, Frederick, Maryland 21702, USA
    J Infect Dis 202:1126-35. 2010
    ..Here, we examine whether any of these may contribute to KS risk in a European AIDS-KS case-control study...
  5. pmc An interleukin-6-related systemic inflammatory syndrome in patients co-infected with Kaposi sarcoma-associated herpesvirus and HIV but without Multicentric Castleman disease
    Thomas S Uldrick
    HIV and AIDS Malignancy Branch, National Cancer Institute Frederick, Frederick, MD, USA
    Clin Infect Dis 51:350-8. 2010
    ..Patients with KSHV-MCD develop fevers, wasting, hypoalbuminemia, cytopenias, and hyponatremia that are related to overproduction of KSHV-encoded viral interleukin (IL)-6 (vIL-6) and human IL-6 (hIL-6)...
  6. pmc Detection of antibodies to Kaposi's sarcoma-associated herpesvirus: a new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA
    Georgina L Mbisa
    Viral Technology Laboratory, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, United States
    J Immunol Methods 356:39-46. 2010
    ..1 ELISA to enable the highly sensitive and specific detection of antibodies to KSHV. Use of this testing strategy will provide a more accurate and reliable diagnostic assessment of KSHV status...
  7. doi request reprint Kaposi's sarcoma-associated herpesvirus transmission and primary infection
    Rachel Bagni
    Viral Oncology Section, AIDS and Cancer Virus Program, SAIC Frederick, NCI Frederick, Frederick, Maryland 21702, USA
    Curr Opin HIV AIDS 4:22-6. 2009
    ..Transmission and risk factors for infection by KSHV are not fully understood. The purpose of this review is to highlight recent advances in our understanding of KSHV transmission in various settings...
  8. ncbi request reprint Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman disease
    Vickie Marshall
    Viral Epidemiology Section, AIDS Vaccine Program, Science Applications International Corporation Frederick, National Cancer Institute Frederick, Frederick, MD 21701, USA
    J Infect Dis 195:645-59. 2007
    ..Kaposi sarcoma (KS)-associated herpesvirus (KSHV) encodes 12 distinct microRNA genes, all of which are located within the latency-associated region that is highly expressed in all KSHV-associated malignancies...
  9. pmc Risk factors for seropositivity to Kaposi sarcoma-associated herpesvirus among children in Uganda
    Katie Wakeham
    Medical Research Council, Uganda Virus Research Institute, Uganda Research Unit on AIDS, Entebbe, Uganda
    J Acquir Immune Defic Syndr 63:228-33. 2013
    ..Local environmental factors, including other infectious agents, may be key...
  10. pmc Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons
    Denise Whitby
    Viral Epidemiology Section, AIDS Vaccine Program, SAIC Frederick, National Cancer Institute, Frederick, MD 21702, USA
    J Virol 77:8159-65. 2003
    ..This establishes baboons as a novel resource to investigate rhadinovirus biology, which can be developed into an animal model system for KSHV-associated human diseases, vaccine development, and therapy evaluation...
  11. ncbi request reprint Risk factors for human herpesvirus 8 seropositivity in the AIDS Cancer Cohort Study
    Sam M Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, 6120 Executive Blvd, Executive Plaza South Rm 8006, Mail Stop Center 7248, Rockville, MD 20852, USA
    J Clin Virol 35:442-9. 2006
    ..Cigarette smoking has been associated with a decreased risk for AIDS-related and classical KS, but whether it is associated with decreased risk of human herpesvirus 8 (HHV-8) infection is unknown...
  12. ncbi request reprint Risk factors for human herpesvirus 8 infection among adults in the United States and evidence for sexual transmission
    Eric A Engels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20892, USA
    J Infect Dis 196:199-207. 2007
    ..Human herpesvirus 8 (HHV-8) causes Kaposi sarcoma. In the United States, transmission routes for HHV-8 are uncertain...
  13. ncbi request reprint Host immunogenetics and control of human herpesvirus-8 infection
    Elizabeth E Brown
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Center for Cancer Research, National Cancer Institute, Rockville 20852, Maryland, USA
    J Infect Dis 193:1054-62. 2006
    ..Host genes important for control of HHV-8 infection are not well characterized...
  14. ncbi request reprint Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity
    Elizabeth E Brown
    National Cancer Institute, 6120 Executive Boulevard, EPS 8005 MSC 7248 Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:926-34. 2006
    ..Among KSHV-seropositive Italians, CKS risk was associated with diplotypes of IL8RB and IL13, supporting laboratory evidence of immune-mediated pathogenesis...
  15. pmc Real-time PCR assay for detection and quantification of hepatitis B virus genotypes A to G
    Tania M Welzel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892, USA
    J Clin Microbiol 44:3325-33. 2006
    ....
  16. ncbi request reprint Human herpesvirus 8 (HHV-8) infection in healthy urban employees from Greece: seroprevalence and associated factors
    Assimina Zavitsanou
    Department of Hygiene and Epidemiology, Athens University Medical School, Athens, Greece
    J Med Virol 79:591-6. 2007
    ..The association between HHV-8 seropositivity and endoscopic examination requires further investigation...
  17. ncbi request reprint Association of clinical progression in classic Kaposi's sarcoma with reduction of peripheral B lymphocytes and partial increase in serum immune activation markers
    Alexander J Stratigos
    Department of Dermatology, University of Athens, Andreas Sygros Hospital, Athens, Greece
    Arch Dermatol 141:1421-6. 2005
    ..To evaluate various immunologic markers in the peripheral blood of patients with early and advanced classic Kaposi's sarcoma (CKS)...
  18. ncbi request reprint Transmission of Kaposi sarcoma-associated herpesvirus between mothers and children in a South African population
    Babatyi I Malope
    Cancer Epidemiology Research Group, National Health Laboratory Services, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 44:351-5. 2007
    ..To assess whether Kaposi sarcoma-associated herpesvirus (KSHV) with or without HIV coinfection in South African mothers is associated with higher KSHV seropositivity in their children...
  19. ncbi request reprint Human herpesvirus 8 infection within families in rural Tanzania
    Sam M Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA
    J Infect Dis 187:1780-5. 2003
    ..2; 95% CI, 1.9-9.4). Our data are consistent with the occurrence of HHV-8 transmission within families, from mothers and other relatives to children via nonsexual routes and between spouses via sexual routes...
  20. ncbi request reprint Prevalence of Kaposi's sarcoma-associated herpesvirus infection in sex workers and women from the general population in Spain
    Silvia de Sanjose
    Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
    Int J Cancer 98:155-8. 2002
    ..All PBMC samples were negative. These results suggest that in low-risk countries for KSHV, oral shedding and heterosexual contacts are potential pathways for KSHV transmission...
  21. ncbi request reprint Mother-to-child transmission of human herpesvirus-8 in South Africa
    Martin Dedicoat
    Liverpool School of Tropical Medicine, Liverpool, and Cancer Research UK Epidemiology Unit, Oxford, United Kingdom
    J Infect Dis 190:1068-75. 2004
    ..1-6.2). The presence of HHV-8 DNA in maternal saliva was unrelated to latent antibodies in children. Saliva could be a route of transmission of HHV-8 from person to person, although other routes cannot be ruled out...
  22. ncbi request reprint Antibody reactivity to latent and lytic antigens to human herpesvirus-8 in longitudinally followed homosexual men
    Robert J Biggar
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA
    J Infect Dis 187:12-8. 2003
    ..Because persons with more advanced infections have higher antibody titers, they are easier to detect, which may skew our understanding of the epidemiology of HHV-8...
  23. ncbi request reprint Detection of kaposi sarcoma-associated herpesvirus DNA in saliva and buffy-coat samples from children with sickle cell disease in Uganda
    Sam M Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, Maryland, USA
    J Infect Dis 190:1382-6. 2004
    ..Detection was associated with K8.1 seropositivity, younger age, and high household density, indicating the importance of in-household person-to-person transmission, likely via saliva...
  24. pmc Sexually transmissible infections and prostate cancer risk
    Wen Yi Huang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:2374-81. 2008
    ..Sexually transmissible infections (STI) have been variably associated with increased risks of prostate cancer, largely in case-control studies...
  25. ncbi request reprint Kaposi's sarcoma-associated herpesvirus infection in elderly Jews and non-Jews from New York City
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Int J Epidemiol 31:946-50. 2002
    ..Elderly Jews have relatively high KS risk, but it is unclear whether this indicates heightened prevalence of KS-associated herpesvirus (KSHV), the KS agent. We studied Jewish and non-Jewish patients at a New York City geriatrics clinic...
  26. ncbi request reprint Immunoblastic lymphoma in persons with AIDS-associated Kaposi's sarcoma: a role for Kaposi's sarcoma-associated herpesvirus
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer and Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Mod Pathol 16:424-9. 2003
    ..We conclude that Kaposi's sarcoma-associated herpesvirus is present in some immunoblastic lymphomas in persons with AIDS-associated Kaposi's sarcoma...
  27. ncbi request reprint Impact of interleukin-10 polymorphisms (-1082 and -3575) on the survival of patients with lymphoid neoplasms
    Eva Domingo-Domenech
    Department of Hematology, Institut Catala d Oncologia, Avda Gran Via s n, Km 2 7, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Haematologica 92:1475-81. 2007
    ..The aim of this study was to explore the association between polymorphisms of IL-10-(1082A>G) and IL-10-(3575T>A) with the overall survival in patients with lymphoid neoplasms...
  28. ncbi request reprint Mouthwash as a low-cost and safe specimen transport medium for human papillomavirus DNA testing of cervicovaginal specimens
    Philip E Castle
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 5004, EPS MSC 7234, Bethesda, MD 20892 7234, USA
    Cancer Epidemiol Biomarkers Prev 16:840-3. 2007
    ..We suggest that mouthwash might be used as a low-cost, safe, nonflammable storage and transport medium for cervical specimens for HPV DNA testing in cervical cancer screening programs...
  29. pmc Combining assays for estimating prevalence of human herpesvirus 8 infection using multivariate mixture models
    Ruth M Pfeiffer
    Biostatistics Branch, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Biostatistics 9:137-51. 2008
    ..We assess model performance in simulations and present results from applying various parameterizations of the model to the Ugandan study...
  30. pmc Seroprevalence and risk factors for human herpesvirus 8 infection, rural Egypt
    Sam M Mbulaiteye
    National Cancer Institute, Bethesda, MD, USA
    Emerg Infect Dis 14:586-91. 2008
    ..1, 95% CI 0.3-16.4), but marginal for women (OR 1.5, 95% CI 1.0-2.5). Our findings suggest salivary and possible nosocomial HHV-8 transmission in rural Egypt...
  31. doi request reprint Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma
    Patrizia Barozzi
    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Via del Pozzo 71, Modena, Italy
    Transplantation 86:738-44. 2008
    ..HHV-8-specific T-cell responses are required to achieve posttransplant KS remission, and may be restored under SRL, while maintaining effective immunosuppression...
  32. ncbi request reprint One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia
    Kyoung Mu Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd EPS 8118, Bethesda, MD 20892 7240, USA
    Hum Genet 122:525-33. 2007
    ..01). In conclusion, the results of this study suggest that genetic polymorphisms of one-carbon metabolism genes such as MTHFR and TYMS may influence susceptibility to NHL...
  33. pmc Human herpesvirus 8 load and progression of AIDS-related Kaposi sarcoma lesions
    Martin M Nsubuga
    Makerere University Medical School, Kampala, Uganda
    Cancer Lett 263:182-8. 2008
    ..We investigated these relationships in persons with AIDS...
  34. doi request reprint No evidence of sexual transmission of Kaposi's sarcoma herpes virus in a heterosexual South African population
    Babatyi I Malope
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa
    AIDS 22:519-26. 2008
    ..The transmission of Kaposi's sarcoma herpes virus (KSHV) in men who have sex with men is clearly associated with sexual risk factors, but evidence of heterosexual transmission of KSHV is conflicting...
  35. doi request reprint Human herpesvirus 8 seroprevalence among children and adolescents in the United States
    Lesley A Anderson
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Pediatr Infect Dis J 27:661-4. 2008
    ..4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status...
  36. ncbi request reprint Risk factors for human Herpesvirus 8 infection and AIDS-associated Kaposi's sarcoma among men who have sex with men in a European multicentre study
    Elisa Martro
    Centre d Estudis Epidemiològics sobre l HIV SIDA de Catalunya, Departament de Salut, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
    Int J Cancer 120:1129-35. 2007
    ....
  37. ncbi request reprint A pilot study of cidofovir in patients with kaposi sarcoma
    Richard F Little
    HIV and AIDS Malignancy Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
    J Infect Dis 187:149-53. 2003
    ..This study does not provide proof of principle for the treatment of KS with CDV. However, it remains possible that antiherpesvirus therapy can be developed for herpes-induced tumors...
  38. ncbi request reprint Risk factors for Kaposi's sarcoma-associated herpesvirus infection among HIV-1-infected pregnant women in the USA
    James J Goedert
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20892, USA
    AIDS 17:425-33. 2003
    ..We sought to identify risk factors for infection with the Kaposi's Sarcoma-associated herpesvirus (KSHV) among pregnant women and to examine a reported association of KSHV with injecting drug use (IDU) and hepatitis C virus (HCV) infection...
  39. ncbi request reprint Detection and quantification of Kaposi's sarcoma-associated herpesvirus to predict AIDS-associated Kaposi's sarcoma
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    AIDS 17:1847-51. 2003
    ..To identify immunologic and virologic predictors of AIDS-associated Kaposi's sarcoma (KS)...
  40. ncbi request reprint Human herpesvirus 8 infection and transfusion history in children with sickle-cell disease in Uganda
    Sam M Mbulaiteye
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 95:1330-5. 2003
    ..We studied the association between HHV-8 seropositivity and transfusion history among children with sickle-cell disease in Uganda, where HHV-8 infection is common in blood donors...
  41. ncbi request reprint Seroprevalence of human herpesvirus 8 among injection drug users in San Francisco
    Jonnae Atkinson
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    J Infect Dis 187:974-81. 2003
    ..These results are consistent with the occurrence of bloodborne transmission of HHV-8 among IDUs...
  42. ncbi request reprint Amino acid residue at position 13 in HLA-DR beta chain plays a critical role in the development of Kaposi's sarcoma in AIDS patients
    Antoni Gayà
    Fundació Banc de Sang i Teixits, Palma de Mallorca, Spain
    AIDS 18:199-204. 2004
    ..In 1994 human herpesvirus 8 (HHV-8) was identified as the causative agent of Kaposi's sarcoma (KS). Moreover, the crucial role of HLA molecules in determining susceptibility to several infections was recognized...
  43. ncbi request reprint Water, socioeconomic factors, and human herpesvirus 8 infection in Ugandan children and their mothers
    Sam M Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    J Acquir Immune Defic Syndr 38:474-9. 2005
    ..Human herpesvirus 8 (HHV-8) infection is common in sub-Saharan Africa, but its distribution is uneven. Transmission occurs during childhood within families by unclear routes...
  44. ncbi request reprint A common genetic variant in FCGR3A-V158F and risk of Kaposi sarcoma herpesvirus infection and classic Kaposi sarcoma
    Elizabeth E Brown
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 14:633-7. 2005
    ..05). Our findings suggest that gender differences could possibly modify the effect of FCGR3A on risk of KSHV infection and CKS. Additional studies are required to confirm these relationships and determine their etiologic significance...
  45. pmc Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma
    Motoki Kurokawa
    Department of Dermatology, Medical College, University of Miyazaki, Japan
    Blood 106:235-40. 2005
    ..AZT inhibits NF-kappaB and up-regulates EBV gene expression in primary EBV+ BLs. AZT with hydroxyurea may represent an inexpensive, targeted regimen for endemic BL...
  46. ncbi request reprint Correlates of Human Herpesvirus-8 DNA detection among adults in Italy without Kaposi sarcoma
    Elizabeth E Brown
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Rockville, MD 20852, USA
    Int J Epidemiol 34:1110-7. 2005
    ..The presence of Human Herpesvirus-8 (HHV8) DNA is predictive of Kaposi sarcoma (KS) among patients with HIV-associated or iatrogenic immunosuppression. However, correlates of HHV8-DNA detection in the general population remain undefined...
  47. ncbi request reprint Distribution of Epstein-Barr viral load in serum of individuals from nasopharyngeal carcinoma high-risk families in Taiwan
    Xiaohong Yang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA
    Int J Cancer 118:780-4. 2006
    ....
  48. ncbi request reprint Sexual behaviour and human herpesvirus 8 infection in homosexual men in Australia
    Andrew E Grulich
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Level 2, 376 Victoria Street, Sydney, NSW 2010 Australia
    Sex Health 2:13-8. 2005
    ..Human herpesvirus 8 (HHV-8) is a common sexually transmitted agent among homosexual men, but there are few Australian data. We aimed to describe the prevalence and risk factors for seropositivity to HHV-8 in Australian homosexual men...
  49. ncbi request reprint High levels of Epstein-Barr virus DNA in saliva and peripheral blood from Ugandan mother-child pairs
    Sam M Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, Maryland, USA
    J Infect Dis 193:422-6. 2006
    ..Our results indicate that EBV infection persists, with virus readily detectable in saliva and buffy coats from persons without apparent symptoms in Africa...
  50. ncbi request reprint Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium
    Nathaniel Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Lancet Oncol 7:27-38. 2006
    ..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
  51. ncbi request reprint Molecular evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus in Uganda and K1 gene evolution within the host
    Sam Mbulaiteye
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland 21701, USA
    J Infect Dis 193:1250-7. 2006
    ..Epidemiological studies of Kaposi sarcoma (KS)-related herpesvirus (KSHV) indicate that having a KSHV-seropositive mother is a risk factor for KSHV infection in children...
  52. ncbi request reprint Virologic, hematologic, and immunologic risk factors for classic Kaposi sarcoma
    Elizabeth E Brown
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer 107:2282-90. 2006
    ....
  53. ncbi request reprint Hepatitis C and risk of lymphoma: results of the European multicenter case-control study EPILYMPH
    Alexandra Nieters
    German Cancer Research Center, Heidelberg, Germany
    Gastroenterology 131:1879-86. 2006
    ..However, previous epidemiologic studies were limited in size to establish an association between HCV infection and specific lymphoma subtypes. We performed a large, multicenter, case-control study to address this question...
  54. ncbi request reprint Transmission of human herpesvirus 8 by sexual activity among adults in Lagos, Nigeria
    Mohamed A Eltom
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics DCEG, National Cancer Institute, 6120 Executive Boulevard, EPS Room 8014, Rockville, MD 20852 MSC 7248, USA
    AIDS 16:2473-8. 2002
    ..Studies in Europe and America suggest spread through homosexual contact, but evidence of heterosexual spread is inconsistent. We examined the association between HHV-8 and markers of risky sexual activity in Nigeria...