Harold H Wen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Efficient decoding of 2D structured illumination with linear phase stepping in X-ray phase contrast and dark-field imaging
    Katherine J Harmon
    Imaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 9:e87127. 2014
  2. pmc Flexible retrospective phase stepping in x-ray scatter correction and phase contrast imaging using structured illumination
    Han Wen
    Imaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e78276. 2013
  3. pmc Interferometric hard x-ray phase contrast imaging at 204 nm grating period
    Han Wen
    Imaging Physic Laboratory, Biophysics and Biochemistry Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Rev Sci Instrum 84:013706. 2013
  4. pmc Theory of oblique and grazing incidence Talbot‑Lau interferometers and demonstration in a compact source x‑ray reflective interferometer
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Opt Express 19:25093-112. 2011
  5. pmc Analytical method to measure three-dimensional strain patterns in the left ventricle from single slice displacement data
    Abbas Nasiraei Moghaddam
    Department of Radiological Sciences, Diagnostic Cardiovascular Imaging Section, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Cardiovasc Magn Reson 12:33. 2010
  6. pmc Single-shot x-ray differential phase-contrast and diffraction imaging using two-dimensional transmission gratings
    Harold H Wen
    Imaging Physics Section, Translational Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Opt Lett 35:1932-4. 2010
  7. pmc Fourier X-ray scattering radiography yields bone structural information
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Radiology 251:910-8. 2009
  8. pmc Spatial harmonic imaging of X-ray scattering--initial results
    Han Wen
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    IEEE Trans Med Imaging 27:997-1002. 2008
  9. pmc Adaptive postprocessing techniques for myocardial tissue tracking with displacement-encoded MR imaging
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bldg 10, B1D416, 10 Center Dr, Bethesda, MD 20892, USA
    Radiology 246:229-40. 2008
  10. pmc Magnetic resonance imaging assessment of myocardial elastic modulus and viscosity using displacement imaging and phase-contrast velocity mapping
    Han Wen
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:538-48. 2005

Collaborators

Detail Information

Publications22

  1. doi request reprint Efficient decoding of 2D structured illumination with linear phase stepping in X-ray phase contrast and dark-field imaging
    Katherine J Harmon
    Imaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 9:e87127. 2014
    ..It is demonstrated with motionless electromagnetic phase stepping and a flexible processing algorithm in x-ray dark-field and phase contrast imaging. ..
  2. pmc Flexible retrospective phase stepping in x-ray scatter correction and phase contrast imaging using structured illumination
    Han Wen
    Imaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e78276. 2013
    ..The algorithm retrospectively determines the spatial distribution of the phase intervals by a Fourier transform method. With this ability, grating-based x-ray imaging becomes more adaptable and robust for broader applications. ..
  3. pmc Interferometric hard x-ray phase contrast imaging at 204 nm grating period
    Han Wen
    Imaging Physic Laboratory, Biophysics and Biochemistry Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Rev Sci Instrum 84:013706. 2013
    ..The phase contrast images showed detailed features as small as 10 μm, and demonstrated the feasibility of high resolution x-ray phase contrast imaging with nanometer scale gratings...
  4. pmc Theory of oblique and grazing incidence Talbot‑Lau interferometers and demonstration in a compact source x‑ray reflective interferometer
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Opt Express 19:25093-112. 2011
    ..Based on the theory, we propose a practical method to correct for non-parallelism of the grating planes, and demonstrate its effectiveness with a polychromatic hard x-ray reflective interferometer...
  5. pmc Analytical method to measure three-dimensional strain patterns in the left ventricle from single slice displacement data
    Abbas Nasiraei Moghaddam
    Department of Radiological Sciences, Diagnostic Cardiovascular Imaging Section, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Cardiovasc Magn Reson 12:33. 2010
    ..The technique assumes incompressibility of the myocardium as a physical constraint...
  6. pmc Single-shot x-ray differential phase-contrast and diffraction imaging using two-dimensional transmission gratings
    Harold H Wen
    Imaging Physics Section, Translational Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Opt Lett 35:1932-4. 2010
    ..When compared to previous grating-based interferometry methods, this approach obviates the need for multiple exposures and separate measurements for different directions and thereby accelerates imaging speed...
  7. pmc Fourier X-ray scattering radiography yields bone structural information
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Radiology 251:910-8. 2009
    ..To characterize certain aspects of the microscopic structures of cortical and trabecular bone by using Fourier x-ray scattering imaging...
  8. pmc Spatial harmonic imaging of X-ray scattering--initial results
    Han Wen
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    IEEE Trans Med Imaging 27:997-1002. 2008
    ..This technique is simple to implement, and should help broaden the imaging applications of X-ray scattering...
  9. pmc Adaptive postprocessing techniques for myocardial tissue tracking with displacement-encoded MR imaging
    Han Wen
    National Heart, Lung and Blood Institute, National Institutes of Health, Bldg 10, B1D416, 10 Center Dr, Bethesda, MD 20892, USA
    Radiology 246:229-40. 2008
    ..Supplemental material: http://radiology.rsnajnls.org/cgi/content/full/246/1/229/DC1...
  10. pmc Magnetic resonance imaging assessment of myocardial elastic modulus and viscosity using displacement imaging and phase-contrast velocity mapping
    Han Wen
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:538-48. 2005
    ..Noninvasive, regional assessment of myocardial stiffness using DENSE and PC velocity mapping techniques is accurate in a canine model and feasible in humans...
  11. pmc Electromechanical analysis of infarct border zone in chronic myocardial infarction
    Hiroshi Ashikaga
    Laboratory of Cardiac Energetics, NHLBI, NIH, 10 Center Dr, MSC 1061, Bldg 10, B1D416, Bethesda, MD 20892 1061, USA
    Am J Physiol Heart Circ Physiol 289:H1099-105. 2005
    ..This indicates that impaired function in the border zone is not contributed by electrical factors but results from mechanical interaction between ischemic and normal myocardium...
  12. pmc A grating-based single-shot x-ray phase contrast and diffraction method for in vivo imaging
    Eric E Bennett
    National Heart, Lung, and Blood Institute, National Institutes of Health, Imaging Physics Section, Translational Medicine Branch, 10 Center Drive, MSC 1061, Bethesda, Maryland 20892, USA
    Med Phys 37:6047-54. 2010
    ..They show the source of artifacts in the phase contrast signal and optimal designs that minimize them. They also discuss its current limitations and ways to overcome them...
  13. ncbi request reprint Does binding of Gd-DTPA to myocardial tissue contribute to late enhancement in a model of acute myocardial infarction?
    Ulrich K M Decking
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 49:168-71. 2003
    ..The data from this acute myocardial infarction model do not support the notion that Gd-DTPA binding in the early stages of myocardial damage contributes to delayed enhancement...
  14. pmc The visceral pericardium: macromolecular structure and contribution to passive mechanical properties of the left ventricle
    Paul D Jobsis
    National Heart, Lung, and Blood Institute, National Institutes of Health, MSC 1061, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 293:H3379-87. 2007
    ..Alterations in this layer may occur in various disease states that effect diastolic function...
  15. pmc Selective imaging of nano-particle contrast agents by a single-shot x-ray diffraction technique
    Ashley F Stein
    Imaging Physic Section, Translational Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Opt Express 18:13271-8. 2010
    ..This approach should help the tracking of functionalized particles in cell labeling and targeted therapy...
  16. pmc In vivo study of microcirculation in canine myocardium using the IVIM method
    Virginie Callot
    Laboratory of Cardiac Energetics, NHLBI, NIH, Bethesda, Maryland 20892, USA
    Magn Reson Med 50:531-40. 2003
    ..With vasodilatation by adenosine infusion, a 25% increase in the VVF and a 7% increase in the mean microflow velocity were observed, while no change in the ADC was detected. A 28.5% decrease of the ADC was observed postmortem...
  17. pmc NADH enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP): applications to enzyme and mitochondrial reaction kinetics, in vitro
    Frederic Joubert
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Biophys J 86:629-45. 2004
    ..Initial data support the notion that the NADH regeneration process is far from equilibrium in mitochondria and is potentially controlled by NADH levels as well as several other matrix factors...
  18. pmc Detection of myocardial capillary orientation with intravascular iron-oxide nanoparticles in spin-echo MRI
    Alexandre Vignaud
    Laboratory of Cardiac Energetics, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 55:725-30. 2006
    ..Preliminary results also demonstrate the feasibility of this method for in vivo application to rodent imaging...
  19. pmc Noninvasive measurement of myocardial tissue volume change during systolic contraction and diastolic relaxation in the canine left ventricle
    Ignacio Rodriguez
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, ational Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 55:484-90. 2006
    ..The result supports the notion of high arterial resistance at the microvascular level from intramyocardial pressure during systole...
  20. pmc Rapid-motion-perception based cardiac navigators: using the high flow blood volume as a marker for the position of the heart
    Vinay M Pai
    Department of Radiology, New York University School of Medicine, 650 First Avenue, Room 611, New York, NY 10016, USA
    J Cardiovasc Magn Reson 5:531-43. 2003
    ..43 mm in the SI direction and +/- 0.84 mm in the AP direction. The RaMP navigator is suited for real-time tracking of the bulk translational motion of the heart...
  21. ncbi request reprint Towards new understanding of the heart structure and function
    Francisco Torrent-Guasp
    Denia, Alicante, Spain
    Eur J Cardiothorac Surg 27:191-201. 2005
    ..The benefit of this, of course, would be the most evident in the clinical arena...
  22. ncbi request reprint High-resolution imaging reveals a limit in spatial resolution of blood flow measurements by microspheres
    Ulrich K M Decking
    Department of Cardiovascular Physiology, Heinrich Heine University, 40225 Dusseldorf, Germany
    Am J Physiol Heart Circ Physiol 287:H1132-40. 2004
    ..We propose that at high spatial resolution (<2 microl) structural aspects of the vascular network dominate microsphere distribution, resulting in the organized patterns observed...