Stephanie J Weinstein

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine
    Stephanie J Weinstein
    Divison of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 12:1271-2. 2003
  2. pmc Pigmentation-related phenotypes and risk of prostate cancer
    S J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Br J Cancer 109:747-50. 2013
  3. pmc Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Servies, Bethesda, Maryland, United States of America
    PLoS ONE 7:e40204. 2012
  4. pmc Serum 25-hydroxyvitamin D and risks of colon and rectal cancer in Finnish men
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 173:499-508. 2011
  5. pmc Serum creatinine and prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:2643-9. 2009
  6. pmc One-carbon metabolism biomarkers and risk of colon and rectal cancers
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Nutritional Epidemiology Branch, Suite 320, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:3233-40. 2008
  7. ncbi request reprint Serum and dietary vitamin E in relation to prostate cancer risk
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1253-9. 2007
  8. ncbi request reprint Dietary factors of one-carbon metabolism and prostate cancer risk
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20892, USA
    Am J Clin Nutr 84:929-35. 2006
  9. pmc Serum 25-hydroxyvitamin D and risk of lung cancer in male smokers: a nested case-control study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e20796. 2011
  10. pmc Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    J Nutr 142:866-71. 2012

Detail Information

Publications78

  1. ncbi request reprint Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine
    Stephanie J Weinstein
    Divison of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 12:1271-2. 2003
  2. pmc Pigmentation-related phenotypes and risk of prostate cancer
    S J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Br J Cancer 109:747-50. 2013
    ..Pigmentation-related traits influence endogenous vitamin D synthesis and may alter risk of prostate cancer...
  3. pmc Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Servies, Bethesda, Maryland, United States of America
    PLoS ONE 7:e40204. 2012
    ..Many studies suggest protective effects among smokers and for aggressive prostate cancer, however...
  4. pmc Serum 25-hydroxyvitamin D and risks of colon and rectal cancer in Finnish men
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 173:499-508. 2011
    ..These results provide no evidence to support an inverse association between vitamin D status and colon or rectal cancer risk; instead, they suggest a positive association for colon cancer...
  5. pmc Serum creatinine and prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:2643-9. 2009
    ..We evaluated whether serum creatinine concentration was associated with risk of developing prostate cancer in a prospective cohort of male smokers...
  6. pmc One-carbon metabolism biomarkers and risk of colon and rectal cancers
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Nutritional Epidemiology Branch, Suite 320, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:3233-40. 2008
    ..Folate intake has been associated with reduced colorectal cancer risk; however, few studies have prospectively examined circulating folate or other related one-carbon biomarkers...
  7. ncbi request reprint Serum and dietary vitamin E in relation to prostate cancer risk
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1253-9. 2007
    ..In summary, higher prediagnostic serum concentrations of alpha-tocopherol, but not dietary vitamin E, was associated with lower risk of developing prostate cancer, particularly advanced prostate cancer...
  8. ncbi request reprint Dietary factors of one-carbon metabolism and prostate cancer risk
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20892, USA
    Am J Clin Nutr 84:929-35. 2006
    ..Vitamin B-6, vitamin B-12, methionine, and alcohol can influence folate-related metabolism...
  9. pmc Serum 25-hydroxyvitamin D and risk of lung cancer in male smokers: a nested case-control study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e20796. 2011
    ....
  10. pmc Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    J Nutr 142:866-71. 2012
    ..g., α-tocopherol) under supplementation conditions improves our understanding of the biological determinants of these nutritional exposures and their associations with cancer etiology...
  11. pmc Serum retinol and risk of prostate cancer
    Alison M Mondul
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Am J Epidemiol 173:813-21. 2011
    ..Future studies may clarify the underlying biologic mechanisms of the retinol-prostate cancer association...
  12. ncbi request reprint Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    Margaret E Wright
    Nutritional Epidemiology Branch and the Genetic Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 84:1200-7. 2006
    ..Little is known, however, about the relation between mortality and circulating concentrations of vitamin E resulting from dietary intake, low-dose supplementation, or both...
  13. pmc Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
    J Natl Cancer Inst 101:1272-9. 2009
    ..The mitogenic and growth-stimulatory effects of insulin-like growth factors appear to play a role in prostate carcinogenesis, yet any direct association of circulating insulin levels and risk of prostate cancer remains unclear...
  14. ncbi request reprint Serum alpha-tocopherol and gamma-tocopherol in relation to prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:396-9. 2005
    ..Participants with higher circulating concentrations of the major vitamin E fractions, alpha-tocopherol and gamma-tocopherol, had similarly lower prostate cancer risk...
  15. pmc Adipokine genes and prostate cancer risk
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Cancer 124:869-76. 2009
    ..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
  16. pmc Serum ghrelin is inversely associated with risk of subsequent oesophageal squamous cell carcinoma
    Gwen Murphy
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20892, USA
    Gut 61:1533-7. 2012
    ..Ghrelin, a hormone which, is also produced in the gastric fundic glands may be a marker of gastric atrophy, but its association with OSCC is not known...
  17. pmc A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancer
    Min Shen
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892, United States
    Lung Cancer 73:133-7. 2011
    ..Telomere length plays an important role in chromosomal stability and tumorigenesis, and its measurement in peripheral white blood cell DNA may be a predictor of the development of lung cancer...
  18. doi request reprint Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    Int J Cancer 123:1154-9. 2008
    ..Supplementation with vitamin E or beta-carotene did not modify the family history-prostate cancer association. This study provides additional evidence that family history is a significant risk factor for prostate cancer...
  19. pmc Helicobacter pylori seropositivity and risk of lung cancer
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 7:e32106. 2012
    ..pylori seropositivity. Despite earlier small studies suggesting that H. pylori may contribute to lung carcinogenesis, H. pylori seropositivity does not appear to be associated with lung cancer...
  20. pmc Advanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 20:1430-8. 2011
    ..AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement...
  21. pmc A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma
    Qing Lan
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, Maryland 20892 7240, USA
    Clin Cancer Res 15:7429-33. 2009
    ..We hypothesized that telomere length in peripheral WBC DNA obtained from healthy individuals would be a predictor of future risk of developing non-Hodgkin lymphoma...
  22. pmc Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8118, MCS 7240, Bethesda, MD 20892 7240, USA
    Carcinogenesis 31:847-9. 2010
    ....
  23. pmc Serum vitamin D and risk of bladder cancer
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Res 70:9218-23. 2010
    ..03). In this prospective study of male smokers, lower serum 25(OH)D was associated with an increased risk of bladder cancer. Future studies should examine the association in other populations, especially nonsmokers and women...
  24. pmc Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective study
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Cancer Res 71:3582-9. 2011
    ..46 (0.23-0.73), P(trend) = 0.002]. Further adjustment for glucose or insulin levels did not change the observed associations. Our findings suggest that sRAGE is inversely associated with pancreatic cancer risk among Finnish male smokers...
  25. doi request reprint A prospective analysis of telomere length and pancreatic cancer in the alpha-tocopherol beta-carotene cancer (ATBC) prevention study
    Shannon M Lynch
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD Center for Clinical Epidemiology and Biostatistics, Center for Genetics and Complex Traits, University of Pennsylvania, Philadelphia, PA
    Int J Cancer 133:2672-80. 2013
    ..03, 95% CI = 0.85-1.22; highest quartile OR = 1.04, 95% CI = 0.60-1.79). This is the first prospective study to suggest an association between longer blood leukocyte telomere length and increased pancreatic cancer risk. ..
  26. pmc Mitochondrial DNA copy number and pancreatic cancer in the alpha-tocopherol beta-carotene cancer prevention study
    Shannon M Lynch
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1912-9. 2011
    ..14, 95% CI = 0.53-2.45, continuous OR = 1.05, 95% CI = 0.93-1.18). Our results support the hypothesis that mtDNA copy number is associated with pancreatic cancer and could possibly serve as a biomarker for pancreatic cancer development...
  27. pmc Serum C-reactive protein and risk of pancreatic cancer in two nested, case-control studies
    Jason B Douglas
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 20:359-69. 2011
    ..Many epidemiologic studies have examined the association between C-reactive protein (CRP) and risk of cancer with inconsistent results...
  28. pmc Genetic variants reflecting higher vitamin e status in men are associated with reduced risk of prostate cancer
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, NIH, Bethesda, MD
    J Nutr 144:729-33. 2014
    ..This study suggests that polymorphisms near BUD13/ZNF259/APOA5, involved in vitamin E transport and metabolism, may be associated with lower risk of prostate cancer. This trial was registered at clinicaltrials.gov as NCT00002540. ..
  29. pmc The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma
    Summer S Han
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7231, USA
    Hum Mol Genet 21:1190-200. 2012
    ..72 × 10(-9), per-allele OR = 1.28, 95% CI: 1.18-1.39) In conclusion, we report that chromosome 2p21 harbors a complex genetic architecture for common RCC risk variants...
  30. pmc The relationship between serum ghrelin and the risk of gastric and esophagogastric junctional adenocarcinomas
    Gwen Murphy
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 3034, Rockville, MD 20892, USA
    J Natl Cancer Inst 103:1123-9. 2011
    ..However, the relationship between ghrelin and the risk of gastric and esophagogastric junctional cancers has not been investigated...
  31. pmc Circulating 25-hydroxyvitamin D and risk of pancreatic cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Rachael Z Stolzenberg-Solomon
    National Cancer Institute, Bethesda, Maryland 20852, USA
    Am J Epidemiol 172:81-93. 2010
    ..12, 95% confidence interval: 1.23, 3.64). Given this result, recommendations to increase vitamin D concentrations in healthy persons for the prevention of cancer should be carefully considered...
  32. pmc Circulating 25-hydroxyvitamin D, vitamin D-binding protein and risk of prostate cancer
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20982 7242, USA
    Int J Cancer 132:2940-7. 2013
    ..47, 95% CI: 0.98-2.20, p-trend 0.10, p-interaction = 0.02). Our data suggest that the primary vitamin D carrier protein, DBP, modulates the impact of vitamin D status on prostate cancer...
  33. pmc Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Cancer Res 73:2211-20. 2013
    ..Our findings could have implications for targeted prevention strategies. However, other smoking-related diseases, as well as practical and ethical considerations, need to be considered before any recommendations could be made...
  34. ncbi request reprint No association between serum insulin-like growth factor (IGF)-I, IGF-binding protein-3, and lung cancer risk
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS 3044, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 15:2010-2. 2006
  35. pmc Genome-wide association study of circulating retinol levels
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Hum Mol Genet 20:4724-31. 2011
    ..31× 10(-5)). Discovery of common genetic variants associated with serum retinol levels may provide further insight into the contribution of retinol and other vitamin A compounds to the development of cancer and other complex diseases...
  36. doi request reprint Flavonoid intake and risk of pancreatic cancer in male smokers (Finland)
    Gerd Bobe
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, 6120 Executive Boulevard, Room 3022, Rockville, MD 20852 7232, USA
    Cancer Epidemiol Biomarkers Prev 17:553-62. 2008
    ..Our data suggest that a flavonoid-rich diet may decrease pancreatic cancer risk in male smokers not consuming supplemental alpha-tocopherol and/or beta-carotene...
  37. pmc Predictors of fasting serum insulin and glucose and the risk of pancreatic cancer in smokers
    Cari L Meinhold
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 20:681-90. 2009
    ..A history of type 2 diabetes is one of few consistent risk factors for pancreatic cancer. Potentially modifiable factors related to fasting insulin and glucose concentrations may influence pancreatic cancer risk...
  38. doi request reprint Cigarette smoking and cancer: intensity patterns in the alpha-tocopherol, beta-carotene cancer prevention study in Finnish men
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852
    Am J Epidemiol 167:970-5. 2008
    ..Consistency of intensity patterns suggested a general phenomenon and may provide clues to the molecular basis of smoking-related cancer risk...
  39. pmc Prediagnostic total and high-density lipoprotein cholesterol and risk of cancer
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 18:2814-21. 2009
    ..We examined the relationship between serum total and HDL cholesterol and risk of overall and site-specific cancers among 29,093 men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort...
  40. pmc Genetic variation in the vitamin d pathway in relation to risk of prostate cancer--results from the breast and prostate cancer cohort consortium
    Alison M Mondul
    National Cancer Institute, NIH, 6120 Executive Blvd, Suite 320, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 22:688-96. 2013
    ..We examined prostate cancer risk in relation to single-nucleotide polymorphisms (SNP) in four genes shown to predict circulating levels of 25(OH)D...
  41. pmc Metabolomic profile of response to supplementation with β-carotene in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    Alison M Mondul
    Nutritional Epidemiology Branch and the Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
    Am J Clin Nutr 98:488-93. 2013
    ..Two chemoprevention trials found that supplementation with β-carotene increased the risk of lung cancer and overall mortality. The biologic basis of these findings remains poorly understood...
  42. pmc Pre-diagnostic circulating vitamin D and risk of melanoma in men
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e35112. 2012
    ..The aim of this study is to investigate the association between serum vitamin D [25(OH)D] levels and melanoma in a cohort of older, middle-aged Finnish male smokers...
  43. pmc Application of a novel score test for genetic association incorporating gene-gene interaction suggests functionality for prostate cancer susceptibility regions
    Julia Ciampa
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA
    Hum Hered 72:182-93. 2011
    ..We use our method in applications designed to detect interactions that generate hypotheses about the functionality of prostate cancer (PRCA) susceptibility regions...
  44. pmc Serum 25-hydroxy vitamin D and prostate cancer risk in a large nested case-control study
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20982, USA
    Cancer Epidemiol Biomarkers Prev 20:1850-60. 2011
    ..Vitamin D compounds inhibit prostate tumorigenesis experimentally, but epidemiologic data are inconsistent with respect to prostate cancer risk, with some studies suggesting nonsignificant positive associations...
  45. ncbi request reprint Glioma risk in relation to serum levels of insulin-like growth factors
    Stefan Lonn
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7053, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 16:844-6. 2007
    ..3; 95% confidence interval, 0.1-0.7). The results encourage future research on IGFs in relation to brain tumors in larger studies...
  46. pmc Circulating 25-hydroxyvitamin D and risk of esophageal and gastric cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Christian C Abnet
    National Cancer Institute, Bethesda, Maryland 20852, USA
    Am J Epidemiol 172:94-106. 2010
    ..31, 0.96). Subgroup analyses by alcohol consumption produced opposing trends. Results do not support the hypothesis that interventions aimed at increasing vitamin D status would lead to a lower risk of these highly fatal cancers...
  47. pmc Iron in relation to gastric cancer in the Alpha-tocopherol, Beta-carotene Cancer Prevention Study
    Michael B Cook
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS Suite 550 Room 5014, Bethesda, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 21:2033-42. 2012
    ..We used the prospective Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study to assess whether iron metrics were associated with gastric cardia cancer (GCC) and gastric noncardia cancer (GNCC)...
  48. pmc Genome-wide association study identifies common variants associated with circulating vitamin E levels
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics and Core Genotyping Facility, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Hum Mol Genet 20:3876-83. 2011
    ..In one of the two male GWAS cohorts (n= 992), no SNPs were significantly associated with gamma-tocopherol concentrations after including data from the replication sample for 71 independent SNPs with P< 1 × 10(-4) identified...
  49. pmc Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Carcinogenesis 30:769-76. 2009
    ..Results from the most comprehensive evaluation of serum vitamin D and its related genes to date suggest that tag SNPS in the 3' UTR of VDR may be associated with risk of prostate cancer in men with low vitamin D status...
  50. pmc Circulating 25-hydroxyvitamin D and risk of non-hodgkin lymphoma: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Mark P Purdue
    National Cancer Institute, Bethesda, Maryland, USA
    Am J Epidemiol 172:58-69. 2010
    ..Future research investigating the biologic basis for the sunlight-NHL association should consider alternative mechanisms, such as immunologic effects...
  51. ncbi request reprint Serum high-density lipoprotein cholesterol and risk of non-hodgkin lymphoma
    Unhee Lim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 67:5569-74. 2007
    ..06). Our findings implicate HDL-C as a preclinical indicator of NHL and warrant further prospective investigations for its etiologic contribution...
  52. ncbi request reprint Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study
    Margaret E Wright
    Divisions of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:1128-35. 2007
    ..The potential benefit of gamma-tocopherol for prostate cancer prevention deserves further attention...
  53. ncbi request reprint Insulin resistance-related gene polymorphisms and risk of prostate cancer
    Steven C Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
  54. pmc Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background
    Idan Menashe
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 7:e29396. 2012
    ..Identification of the aromatic amine metabolism pathway provides support for the ability of this approach to identify pathways with established relevance to bladder carcinogenesis...
  55. pmc Serum total and HDL cholesterol and risk of prostate cancer
    Alison M Mondul
    Department of Health and Human Services, Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 22:1545-52. 2011
    ..Confirmation in additional populations and examination of associations for lipoprotein subfractions are needed...
  56. ncbi request reprint A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland)
    Panagiota N Mitrou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Int J Cancer 120:2466-73. 2007
    ..The results from this large prospective study suggest that intake of calcium or some related component contained in dairy foods is associated with increased prostate cancer risk...
  57. pmc Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  58. ncbi request reprint A case-control study of risk factors for invasive cervical cancer among U.S. women exposed to oncogenic types of human papillomavirus
    Tammy S Shields
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7234, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 13:1574-82. 2004
    ..It is particularly worth considering further why studies of different designs are inconsistent regarding the effect of oral contraceptive use...
  59. pmc Associations between alpha-tocopherol, beta-carotene, and retinol and prostate cancer survival
    Joanne L Watters
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch and Biostatistics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 69:3833-41. 2009
    ..Further investigations, possibly including randomized studies, are needed to confirm this observation...
  60. pmc A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
    Nathaniel Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Nat Genet 42:978-84. 2010
    ..Our findings on common variants associated with bladder cancer risk should provide new insights into the mechanisms of carcinogenesis...
  61. ncbi request reprint Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 132:762-7. 2002
    ..Risks for oral cancer are not folate specific; preventive recommendations for this disease should emphasize the importance of a healthy diet, including substantial intake of fruits...
  62. pmc Soluble receptor for advanced glycation end products and risk of liver cancer
    Kristin A Moy
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hepatology 57:2338-45. 2013
    ..sRAGE and CML-AGE concentrations were inversely associated with liver cancer. Further adjustment for glucose and insulin or exclusion of case subjects with chronic HBV or HCV did not change the associations...
  63. pmc Prediagnostic circulating adipokine concentrations and risk of renal cell carcinoma in male smokers
    Linda M Liao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Carcinogenesis 34:109-12. 2013
    ..These findings provide the strongest evidence to date, suggesting that the association between obesity and RCC is mediated at least in part through the effects of low adiponectin...
  64. pmc Impact of circulating vitamin D binding protein levels on the association between 25-hydroxyvitamin D and pancreatic cancer risk: a nested case-control study
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20982, USA
    Cancer Res 72:1190-8. 2012
    ..Simultaneous examination of DBP and 25(OH)D may be important in determining the association of vitamin D with cancer risk...
  65. pmc A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Hum Mol Genet 20:4282-9. 2011
    ..Our findings suggest that genetic variation in SLC14A1 could provide new etiological insights into bladder carcinogenesis...
  66. pmc A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
    Blood 112:4247-9. 2008
    ..0; 3.2 [0.7-15.7]; 14.1 [1.9-103.2]; P(trend) = .009). These results suggest that mtDNA copy number could be associated with the risk of NHL, particularly CLL/SLL...
  67. ncbi request reprint Serum selenium and the risk of cervical cancer among women in the United States
    Frances E Thompson
    National Cancer Institute, Division of Cancer Control and Population Sciences, Applied Research Program, Risk Factor Monitoring and Methods Branch, EPN 4016, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    Cancer Causes Control 13:517-26. 2002
    ..To explore the relationship between serum selenium and cervical cancer...
  68. pmc Circulating thyroxine, thyroid-stimulating hormone, and hypothyroid status and the risk of prostate cancer
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
    PLoS ONE 7:e47730. 2012
    ..We undertook a prospective analysis of thyroid hormones and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study...
  69. ncbi request reprint Healthy Eating Index scores are associated with blood nutrient concentrations in the third National Health And Nutrition Examination Survey
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Insititue, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    J Am Diet Assoc 104:576-84. 2004
    ..Our objectives were to assess the HEI as a measure of dietary status through its correlation with nutritional biomarkers and to identify those biomarkers most associated with diet quality and healthful food intake patterns...
  70. ncbi request reprint Nutritional and genetic inefficiencies in one-carbon metabolism and cervical cancer risk
    Regina G Ziegler
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 132:2345S-2349S. 2002
    ....
  71. pmc Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3)
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Mol Genet 18:3749-57. 2009
    ..8%, P = 1.82 x 10(-6)). Genetic variation in genes in the sex steroid hormone pathway is associated with differences in circulating SHBG and sex steroid hormones...
  72. pmc A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma
    Todd M Gibson
    Yale School of Public Health, 60 College Street, New Haven, CT 06520, USA
    Cancer Causes Control 21:1061-9. 2010
    ..We conducted a nested case-control study within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, a prospective study of Finnish male smokers aged 50-69 at baseline...
  73. pmc Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States
    Todd M Gibson
    Yale School of Public Health, New Haven, CT, USA
    Am J Clin Nutr 94:1053-62. 2011
    ..Therefore, mandatory folic acid fortification of grain products in the United States may have unintended negative consequences...
  74. pmc Serum 25-hydroxyvitamin D and risk of oropharynx and larynx cancers in Finnish men
    Hannah Arem
    Yale School of Public Health, Department ofChronic Disease Epidemiology, New Haven, Connecticut, USA
    Cancer Epidemiol Biomarkers Prev 20:1178-84. 2011
    ..Prolonged darker months in Finland are associated with lower levels of ultraviolet B radiation, raising concerns about low vitamin D levels...
  75. pmc Detectable clonal mosaicism and its relationship to aging and cancer
    Kevin B Jacobs
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland, USA
    Nat Genet 44:651-8. 2012
    ..4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases...
  76. pmc Serum vitamin D and risk of bladder cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening trial
    Alison M Mondul
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
    Cancer Epidemiol Biomarkers Prev 21:1222-5. 2012
    ....
  77. pmc Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, USA
    Nat Genet 43:60-5. 2011
    ..31 for rs4765623, which maps to SCARB1, the scavenger receptor class B, member 1 gene (P = 2.6 × 10⁻⁸). Our study reports previously unidentified genomic regions associated with RCC risk that may lead to new etiological insights...
  78. ncbi request reprint Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
    ..Estrogen receptor beta (ESR2) may play a role in modulating prostate carcinogenesis through the regulation of genes related to cell proliferation and apoptosis...