Brant M Weinstein
Affiliation: National Institutes of Health
Moore J, Mulligan T, Yordán N, Castranova D, Pham V, Tang Q, et al
. T Cell Immune Deficiency in zap70 Mutant Zebrafish. Mol Cell Biol. 2016;36:2868-2876 pubmed publisher
..i>zap70 mutant zebrafish show remarkable conservation of immune cell dysfunction as found in mice and humans and will serve as a valuable model to study zap70 immune deficiency. ..
Swift M, Pham V, Castranova D, Bell K, Poole R, Weinstein B. SoxF factors and Notch regulate nr2f2 gene expression during venous differentiation in zebrafish. Dev Biol. 2014;390:116-25 pubmed publisher
..We show that Notch signaling activity present in the dorsal aorta suppresses expression of nr2f2, restricting nr2f2-dependent promotion of venous differentiation to the cardinal vein. ..
Stratman A, Pezoa S, Farrelly O, Castranova D, Dye L, Butler M, et al
. Interactions between mural cells and endothelial cells stabilize the developing zebrafish dorsal aorta. Development. 2017;144:115-127 pubmed publisher
Jung H, Castranova D, Swift M, Pham V, Venero Galanternik M, Isogai S, et al
. Development of the larval lymphatic system in zebrafish. Development. 2017;144:2070-2081 pubmed publisher
..Our results show that major trunk lymphatic vessels are conserved in the zebrafish, and provide a thorough and complete description of trunk lymphatic vessel assembly. ..
Krispin S, Stratman A, Melick C, Stan R, Malinverno M, Gleklen J, et al
. Growth Differentiation Factor 6 Promotes Vascular Stability by Restraining Vascular Endothelial Growth Factor Signaling. Arterioscler Thromb Vasc Biol. 2018;38:353-362 pubmed publisher
..Understanding how GDF6 affects vascular integrity may help to provide insights into hemorrhage and associated vascular pathologies in humans. ..