Research Topics
| D Heather WattsSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The effects of three nonoxynol-9 preparations on vaginal flora and epitheliumD H Watts
Pediatric, Adolescent, Maternal AIDS Branch, CRMC NICHD NIH, Bethesda, MD 20892, USA
J Infect Dis 180:426-37. 1999..Symptoms and colposcopic abnormalities were rare. Changes in levels of vaginal bacteria were transient after single applications of N-9, but adverse effects may be enhanced with frequent, chronic use...- Effects of bacterial vaginosis and other genital infections on the natural history of human papillomavirus infection in HIV-1-infected and high-risk HIV-1-uninfected womenD Heather Watts
National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892 7510, USA
J Infect Dis 191:1129-39. 2005..Whether the natural history of human papillomavirus (HPV) infection is affected by bacterial vaginosis (BV) or Trichomonas vaginalis (TV) infection has not been adequately investigated in prospective studies... 
Birth defects among a cohort of infants born to HIV-infected women on antiretroviral medicationD Heather Watts
Eunice Kennedy Shriver National Institute for Child Health and Human Development, Bethesda, MD, USA
J Perinat Med 39:163-70. 2011..To determine rate of and risk factors for birth defects in infants born to HIV-infected women receiving nucleoside and protease inhibitor antiretroviral (ARV) therapy...- Assessing the risk of birth defects associated with antiretroviral exposure during pregnancyD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA
Am J Obstet Gynecol 191:985-92. 2004..The purpose of this study was to examine teratogenic risk of antiretroviral (ARV) drugs... - Teratogenicity risk of antiretroviral therapy in pregnancyD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, CRMC NICHD NIH, 6100 Executive Boulevard, Room 4B11, Bethesda, MD 20892, USA
Curr HIV/AIDS Rep 4:135-40. 2007..Additional data on risks of antiretrovirals during pregnancy are needed. Providers should report cases of antiretroviral drug exposures during pregnancy to the Antiretroviral Pregnancy Registry... - Maternal toxicity and pregnancy complications in human immunodeficiency virus-infected women receiving antiretroviral therapy: PACTG 316D Heather Watts
National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
Am J Obstet Gynecol 190:506-16. 2004..The purpose of this study was to evaluate rates of maternal toxicity, pregnancy complications, and peripartum morbidity by type and duration of antiretroviral therapy (ART) during pregnancy... - Progression of HIV disease among women following deliveryD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
J Acquir Immune Defic Syndr 33:585-93. 2003..To assess patterns of HIV disease progression among HIV-1-infected women following delivery... - Management of human immunodeficiency virus infection in pregnancyD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research on Mothers and Children, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
N Engl J Med 346:1879-91. 2002 - Treating HIV during pregnancy: an update on safety issuesD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research for Mothers and Children, National Institute of Child Health and Human Development, Rockville, Maryland, USA
Drug Saf 29:467-90. 2006..Concern has been raised, however, that these exposures may lead to persistent mitochondrial dysfunction or later cancers, underscoring the need for long-term surveillance of antiretroviral-exposed, HIV-uninfected infants... - The occurrence of vaginal infections among HIV-infected and high-risk HIV-uninfected women: longitudinal findings of the women's interagency HIV studyD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research on Mothers and Children, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 43:161-8. 2006..CONCLUSIONS:: Declines in BV, TV, and YV represent decreased morbidity for HIV-infected women and, potentially, decreased risk of transmission of HIV, because each has been associated with increased genital detection of HIV... - Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093D Heather Watts
National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA
Contraception 77:84-90. 2008..We evaluated the safety and tolerability of depot medroxyprogesterone acetate (DMPA) among women on ARV... - Assessment of birth defects according to maternal therapy among infants in the Women and Infants Transmission StudyD Heather Watts
Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research on Mothers and Infants, National Institute of Child Health and Human Development NIH, 6100 Executive Boulevard, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 44:299-305. 2007..To evaluate rate and types of birth defects according to timing of antiretroviral exposure among babies born to HIV-infected women... - Effect of pregnancyD Heather Watts
National Institute of Child Health and Human Development, National Institutes of Health, DHHS, USA
J Acquir Immune Defic Syndr 38:S36-8. 2005 - Changing trends in clinical AIDS presentations and survival among HIV-1-infected womenManhattan Charurat
Division of Epidemiology and Prevention, Institute of Human Virology, University of Maryland, Baltimore, MD, USA
J Womens Health (Larchmt) 13:719-30. 2004..To profile trends of clinical AIDS-defining illness (ADI) among a cohort of human immunodeficiency virus (HIV)-infected women over a 12-year period... - The relationship between cocaine use and human papillomavirus infections in HIV-seropositive and HIV-seronegative womenHoward Minkoff
Department of Obstetrics and Gynecology at Maimonides Medical Center and SUNY Downstate, NY 11219, USA
Infect Dis Obstet Gynecol 2008:587082. 2008..Since both cocaine use and HPV infection are common among HIV-positive women, we sought to determine whether use of cocaine and/or crack influences the natural history of HPV among women with or at high risk of HIV... 
No association between antepartum serologic and genital tract evidence of herpes simplex virus-2 coinfection and perinatal HIV-1 transmissionKatherine T Chen
Department of Obstetrics and Gynecology and Epidemiology, Columbia University, New York, NY 10032, USA
Am J Obstet Gynecol 198:399.e1-5. 2008..The purpose of this study was to assess the risk of perinatal HIV-1 transmission in women who are coinfected with herpes simplex virus-2 (HSV-2)...- The impact of sex and contraceptive therapy on the plasma and intracellular pharmacokinetics of zidovudineFrancesca T Aweeka
Drug Research Unit, University of California, San Francisco, California 94143 0622, USA
AIDS 20:1833-41. 2006..This study evaluated the impact of female sex and contraceptive therapy on zidovudine plasma and intracellular pharmacokinetics and the impact of contraceptive therapy on HIV viral load... - HIV type 1 zidovudine (ZDV) resistance in blood and uterine cervical secretions of pregnant womenLisa M Frenkel
University of Washington, Seattle, Washington 98109, Children s Hospital and Medical Center of Seattle, Seattle, Washington 98105, USA
AIDS Res Hum Retroviruses 22:870-3. 2006..However, in only 1 (1.8%) of 57 pregnancies evaluated was resistant virus limited to the cervical secretions. ZDV-resistant virus is rarely limited to the female genital tract... - Relationship of pregnancy to human papillomavirus among human immunodeficiency virus-infected womenHoward Minkoff
Department of Obstetrics and Gynecology, Maimonides Medical Center and SUNY Downstate, Brooklyn, New York, USA
Obstet Gynecol 108:953-60. 2006.... - Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant womenJashvant D Unadkat
Department of Pharmaceutics, University of Washington, Box 357610, Seattle, WA 98195, USA
Antimicrob Agents Chemother 51:783-6. 2007..Indinavir area under the plasma concentration-time curve was 68% lower antepartum versus postpartum, suggesting increased intestinal and/or hepatic CYP3A activity during pregnancy... - Analysis of standard methods for diagnosing vaginitis: HIV infection does not complicate the diagnosis of vaginitisBeverly E Sha
Department of Medicine, Section of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA
J Low Genit Tract Dis 11:240-50. 2007..We sought to determine whether the standard diagnostic methods for vaginitis behave similarly among HIV-infected and at-risk seronegative women... - Nevirapine concentrations in newborns receiving an extended prophylactic regimenMark Mirochnick
Department of Pediatrics, Boston University School of Medicine, Boston, MA 02118, USA
J Acquir Immune Defic Syndr 47:334-7. 2008..The optimal neonatal antiretroviral (ARV) regimen for prevention of HIV mother-to-child transmission (MTCT) is unknown for infants born to mothers who receive no ARVs during pregnancy... - Protease inhibitor-based antiretroviral therapy and glucose tolerance in pregnancy: AIDS Clinical Trials Group A5084Jane Hitti
University of Washington, Seattle, WA, USA
Am J Obstet Gynecol 196:331.e1-7. 2007..The objective of the study was to determine whether protease inhibitors increase glucose intolerance and insulin resistance in pregnancy... - Outcomes after treatment of cervical intraepithelial neoplasia among women with HIVL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9640, USA
J Low Genit Tract Dis 11:90-7. 2007..To describe outcomes after treatment of cervical intraepithelial neoplasia (CIN) in women with HIV... - Association of cutaneous anergy with human papillomavirus and cervical neoplasia in HIV-seropositive and seronegative womenTiffany G Harris
Albert Einstein College of Medicine, Bronx, New York 10461, USA
AIDS 21:1933-41. 2007..This study assessed the relationship of anergy test results with cervical infection by human papillomavirus (HPV) and cervical neoplasia in HIV-seropositive and seronegative women... - Contraceptive use among U.S. women with HIVL Stewart Massad
Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
J Womens Health (Larchmt) 16:657-66. 2007..To describe trends in and correlates of use of contraception and sterilization among women with the human immunodeficiency virus (HIV)... - Reproductive health of adolescent girls perinatally infected with HIVSusan B Brogly
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Mass 02115 6017, USA
Am J Public Health 97:1047-52. 2007..We sought to describe the reproductive health of adolescent girls perinatally infected with HIV... 
Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USAMarie Louise Newell
Centre of Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, UK
BMC Infect Dis 7:60. 2007....- Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infantsCarmen D Zorrilla
Obstetrics and Gynecology Department, UPR School of Medicine, P O Box 365067, San Juan, Puerto Rico
Antimicrob Agents Chemother 51:2208-10. 2007..Two had elevated liver transaminases and amylase. Seven infant adverse events were possibly treatment related (anemia, neutropenia, and hyperbilirubinemia)... - Effects of HIV infection and its treatment on self-reported menstrual abnormalities in womenL Stewart Massad
Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
J Womens Health (Larchmt) 15:591-8. 2006..To describe menstrual abnormalities among women with HIV... - Effect of hormonal contraceptive use on plasma HIV-1-RNA levels among HIV-infected womenHelen E Cejtin
Department of Obstetrics and Gynecology, Cook County Hospital, Chicago, IL, USA
AIDS 17:1702-4. 2003..There did not appear to be an association between hormonal contraception use and HIV-1-RNA levels in our study. There was a small increase in CD4 cell counts among hormonal users of doubtful clinical significance... - Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant womenEdward P Acosta
University of Alabama at Birmingham, Birmingham, Alabama, USA
Antimicrob Agents Chemother 48:430-6. 2004..These PK results suggest that SQV-RTV at 800/100 mg b.i.d. appears to be a reasonable treatment option for this population... - HPV testing for triage of HIV-infected women with papanicolaou smears read as atypical squamous cells of uncertain significanceL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois School of Medicine, Springfield, Illinois 62794, USA
J Womens Health (Larchmt) 13:147-53. 2004.... - Relationship between smoking and human papillomavirus infections in HIV-infected and -uninfected womenHoward Minkoff
Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York, USA
J Infect Dis 189:1821-8. 2004..Among HIV-infected women, smoking is associated with a significantly higher prevalence and incidence of HPV infection. Smoking during HIV infection may alter the natural history of HPV infection and increase the risk of cervical disease... - Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022Jane Hitti
University of Washington, Seattle, 98195, USA
J Acquir Immune Defic Syndr 36:772-6. 2004..To compare the safety of nelfinavir and nevirapine-based antiretroviral treatment in HIV-1-infected pregnant women... - The relationship of pregnancy to human immunodeficiency virus disease progressionHoward Minkoff
Department of Obstetrics and Gynecology, Maimonides Medical Center and SUNY Downstate, Brooklyn, New York 11219, USA
Am J Obstet Gynecol 189:552-9. 2003..This study was undertaken to determine the effect of pregnancy on progression of human immunodeficiency virus (HIV) disease... - Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV StudyKiros Berhane
Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
J Acquir Immune Defic Syndr 37:1245-52. 2004..Anemia is common in HIV-infected individuals and may be associated with decreased survival... - Effect of hard-drug use on CD4 cell percentage, HIV RNA level, and progression to AIDS-defining class C events among HIV-infected womenLorna E Thorpe
New York City Department of Health and Mental Hygiene, New York, NY, USA
J Acquir Immune Defic Syndr 37:1423-30. 2004..65; 95% confidence interval, 1.00-2.72), especially herpes, pulmonary tuberculosis, and recurrent pneumonia. Hard-drug-using women may have a higher risk for nonfatal opportunistic infections... - Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332Nancy A Wade
Department of Pediatrics, Children s Hospital at Albany Medical Center, Albany, New York 12208, USA
J Infect Dis 190:2167-74. 2004..No infants had positive HIV viral diagnostic tests. d4T with or without 3TC is a potential alternative to ZDV for HIV-infected pregnant women... - Variants of human papillomaviruses 16 and 18 and their natural history in human immunodeficiency virus-positive womenNicolas F Schlecht
Albert Einstein College of Medicine, Department of Epidemiology and Population Health, 1300 Morris Park Avenue, Bronx, NY 10461, USA
J Gen Virol 86:2709-20. 2005..If non-European variants are more oncogenic, the effect may involve a late stage in cervical tumorigenesis... - Improved obstetric outcomes and few maternal toxicities are associated with antiretroviral therapy, including highly active antiretroviral therapy during pregnancyRuth E Tuomala
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
J Acquir Immune Defic Syndr 38:449-73. 2005..3, 95% CI: 0.2-0.7). Benefits of ART continue to outweigh observed risks... - Incidence of cervical squamous intraepithelial lesions associated with HIV serostatus, CD4 cell counts, and human papillomavirus test resultsTiffany G Harris
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
JAMA 293:1471-6. 2005.... - Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive womenHoward D Strickler
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer 1308, Bronx, NY 10461, USA
J Natl Cancer Inst 97:577-86. 2005.... - Association of cigarette smoking with HIV prognosis among women in the HAART era: a report from the women's interagency HIV studyJoseph G Feldman
SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
Am J Public Health 96:1060-5. 2006..We assessed the association of cigarette smoking with the effectiveness of highly active antiretroviral therapy (HAART) among low-income women... - Squamous cervical lesions in women with human immunodeficiency virus: long-term follow-upL Stewart Massad
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Obstet Gynecol 111:1388-93. 2008..To estimate the frequency of and trends in abnormal Pap test results in women with human immunodeficiency virus (HIV) and HIV-uninfected women... - A double-blind, randomized, placebo-controlled trial of acyclovir in late pregnancy for the reduction of herpes simplex virus shedding and cesarean deliveryD Heather Watts
Department of Obstetrics and Gynecology, University of Washington, Seattle, USA
Am J Obstet Gynecol 188:836-43. 2003..Neonatal outcomes were similar between groups. CONCLUSION: Acyclovir significantly reduced, but did not eliminate, herpes simplex virus lesions and detection in late pregnancy... - Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV studyAlexandra M Levine
Department of Medicine, Division of Hematology, University of Southern California, Los Angeles, CA 90033, USA
Arch Intern Med 166:405-10. 2006..Neither the effect of highly active antiretroviral therapy (HAART) on neutrophil counts nor the significance of neutropenia in terms of survival has previously been evaluated... - Insulin-like growth factor axis and oncogenic human papillomavirus natural historyTiffany G Harris
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Cancer Epidemiol Biomarkers Prev 17:245-8. 2008..07; 95% CI, 0.01-0.66). These prospective data provide initial evidence that the IGF axis may influence the natural history of oncogenic HPV... - Natural history of grade 1 cervical intraepithelial neoplasia in women with human immunodeficiency virusL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
Obstet Gynecol 104:1077-85. 2004..We sought to estimate rates of progression and regression of grade 1 cervical intraepithelial neoplasia (CIN 1) among women with human immunodeficiency virus (HIV)... - Outcome after negative colposcopy among human immunodeficiency virus-infected women with borderline cytologic abnormalitiesL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
Obstet Gynecol 106:525-32. 2005..To estimate the risk of and risk factors for progression among human immunodeficiency virus (HIV)-seropositive women with abnormal cervical cytology but negative colposcopy... - Hysterectomy among women with HIV: indications and incidenceL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
J Acquir Immune Defic Syndr 44:566-8. 2007..To describe hysterectomy rates and indications among women with HIV and to compare them with at-risk HIV-seronegative women... - Prevalence and predictors of Toxoplasma seropositivity in women with and at risk for human immunodeficiency virus infectionOluwatoyin Falusi
Cook County Hospital and Rush Medical College, Chicago, IL 60612, USA
Clin Infect Dis 35:1414-7. 2002..HIV-infected women aged > or =50 years and those born outside of the United States were more likely to have latent Toxoplasma infection, with prevalences of 32% and 41%, respectively...