Michael Waters

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The impact of new technologies on human population studies
    Michael D Waters
    National Center for Toxicogenomics, 111 Alexander Drive, P O Box 12233, MD F1 05, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:349-60. 2003
  2. ncbi request reprint Toxicogenomics and systems toxicology: aims and prospects
    Michael D Waters
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, PO Box 12233, MD F1 05, 111 Alexander Drive, Research Triangle Park, North Carolina 27709 2233, USA
    Nat Rev Genet 5:936-48. 2004
  3. ncbi request reprint Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base
    Michael Waters
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    EHP Toxicogenomics 111:15-28. 2003
  4. ncbi request reprint Toxicogenomic approach for assessing toxicant-related disease
    Michael D Waters
    National Center for Toxigenomics, National Institute of Environmental Health Sciences, P O Box 12233, MD F1 05, 111 Alexander Drive, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:415-24. 2003
  5. pmc CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data
    Michael Waters
    NIEHS, National Center for Toxicogenomics, PO Box 12233, Research Triangle Park, NC 27709, USA
    Nucleic Acids Res 36:D892-900. 2008
  6. ncbi request reprint Toward a checklist for exchange and interpretation of data from a toxicology study
    Jennifer M Fostel
    NIEHS, LMIT ITSS Contract, Research Triangle Park, North Carolina 27709 2233, USA
    Toxicol Sci 99:26-34. 2007
  7. doi request reprint Databases applicable to quantitative hazard/risk assessment--towards a predictive systems toxicology
    Michael Waters
    ILS, Inc, P O Box 13501, Research Triangle Park, NC 27709, USA
    Toxicol Appl Pharmacol 233:34-44. 2008
  8. ncbi request reprint Quality review procedures necessary for rodent pathology databases and toxicogenomic studies: the National Toxicology Program experience
    Gary A Boorman
    Laboratory for Experimental Pathology, Environmental Toxicology Program, National Center for Toxicogenomics, NIEHS, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 30:88-92. 2002
  9. ncbi request reprint Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data
    Jennifer Fostel
    LIMT Lockheed Martin Information Technology LMIT, Research Triangle Park, NC 27709, USA
    Toxicol Sci 88:585-601. 2005
  10. ncbi request reprint Consensus recommendations to promote and advance predictive systems toxicology and toxicogenomics
    Michael Waters
    Integrated Laboratory Systems, Research Triangle Park, North Carolina 27709, USA
    Environ Mol Mutagen 48:400-3. 2007

Detail Information

Publications13

  1. ncbi request reprint The impact of new technologies on human population studies
    Michael D Waters
    National Center for Toxicogenomics, 111 Alexander Drive, P O Box 12233, MD F1 05, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:349-60. 2003
    ..This knowledge can be used to protect susceptible individuals from disease and to reduce adverse exposure and environmentally induced disease...
  2. ncbi request reprint Toxicogenomics and systems toxicology: aims and prospects
    Michael D Waters
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, PO Box 12233, MD F1 05, 111 Alexander Drive, Research Triangle Park, North Carolina 27709 2233, USA
    Nat Rev Genet 5:936-48. 2004
    ....
  3. ncbi request reprint Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base
    Michael Waters
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    EHP Toxicogenomics 111:15-28. 2003
    ..The CEBS development effort will span a decade or more...
  4. ncbi request reprint Toxicogenomic approach for assessing toxicant-related disease
    Michael D Waters
    National Center for Toxigenomics, National Institute of Environmental Health Sciences, P O Box 12233, MD F1 05, 111 Alexander Drive, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:415-24. 2003
    ....
  5. pmc CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data
    Michael Waters
    NIEHS, National Center for Toxicogenomics, PO Box 12233, Research Triangle Park, NC 27709, USA
    Nucleic Acids Res 36:D892-900. 2008
    ..niehs.nih.gov. BID can be accessed via the user interface from https://dir-apps.niehs.nih.gov/arc/. Requests for a copy of BID and for depositing data into CEBS or BID are available at http://www.niehs.nih.gov/cebs-df/...
  6. ncbi request reprint Toward a checklist for exchange and interpretation of data from a toxicology study
    Jennifer M Fostel
    NIEHS, LMIT ITSS Contract, Research Triangle Park, North Carolina 27709 2233, USA
    Toxicol Sci 99:26-34. 2007
    ..It is anticipated that once a toxicology checklist is accepted and put into use, then toxicology databases can be configured to require and output these fields, making it straightforward to annotate data for interpretation by others...
  7. doi request reprint Databases applicable to quantitative hazard/risk assessment--towards a predictive systems toxicology
    Michael Waters
    ILS, Inc, P O Box 13501, Research Triangle Park, NC 27709, USA
    Toxicol Appl Pharmacol 233:34-44. 2008
    ..Each of the public databases has been discussed in prior publications. They will be briefly described in the present report from the perspective of aggregating datasets to augment the data and information contained within them...
  8. ncbi request reprint Quality review procedures necessary for rodent pathology databases and toxicogenomic studies: the National Toxicology Program experience
    Gary A Boorman
    Laboratory for Experimental Pathology, Environmental Toxicology Program, National Center for Toxicogenomics, NIEHS, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 30:88-92. 2002
    ..The lessons learned in assuring data quality in standard rodent studies also applies to the emerging field of toxicogenomics...
  9. ncbi request reprint Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data
    Jennifer Fostel
    LIMT Lockheed Martin Information Technology LMIT, Research Triangle Park, NC 27709, USA
    Toxicol Sci 88:585-601. 2005
    ..To illustrate the utility of the CEBS-DD, we present an example of integrating data from two proteomics and transcriptomics studies of the response to acute acetaminophen toxicity (A. N. Heinloth et al., 2004, Toxicol. Sci. 80, 193-202)...
  10. ncbi request reprint Consensus recommendations to promote and advance predictive systems toxicology and toxicogenomics
    Michael Waters
    Integrated Laboratory Systems, Research Triangle Park, North Carolina 27709, USA
    Environ Mol Mutagen 48:400-3. 2007
    ....
  11. ncbi request reprint Chemical effects in biological systems (CEBS) object model for toxicology data, SysTox-OM: design and application
    Sandhya Xirasagar
    Science Applications International Corporation, 20201 Century Boulevard, 3rd Floor, Germantown, MD 20874, USA
    Bioinformatics 22:874-82. 2006
    ..All of these data types can be integrated in a seamless fashion to enable data query and analysis in a biologically meaningful manner...
  12. ncbi request reprint CEBS object model for systems biology data, SysBio-OM
    Sandhya Xirasagar
    Science Applications International Corporation, 20201 Century Building, 3rd Floor, Germantown, MD 20874, USA
    Bioinformatics 20:2004-15. 2004
    ..Data streams include, but are not limited to, gene expression analysis (transcriptomics), protein expression and protein-protein interaction analysis (proteomics) and changes in low molecular weight metabolite levels (metabolomics)...
  13. pmc Database development in toxicogenomics: issues and efforts
    William B Mattes
    Pfizer Inc, Groton, Connecticut, USA
    Environ Health Perspect 112:495-505. 2004
    ....