Yan Wang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization
    Yan Wang
    Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 71:371-82. 2011
  2. pmc Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection
    Yan Wang
    Laboratory of Clinical Investigation, Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA
    J Chromatogr A 1216:3533-7. 2009
  3. pmc Structural basis of G protein-coupled receptor-G protein interactions
    Jianxin Hu
    Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Nat Chem Biol 6:541-8. 2010
  4. pmc Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells
    Wook Kim
    National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Diabetes 60:1198-209. 2011
  5. pmc Structural basis of toll-like receptor 3 signaling with double-stranded RNA
    Lin Liu
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Science 320:379-81. 2008

Collaborators

Detail Information

Publications5

  1. pmc The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization
    Yan Wang
    Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 71:371-82. 2011
    ..Together, our results suggest menin as an important novel negative regulator of AKT kinase activity...
  2. pmc Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection
    Yan Wang
    Laboratory of Clinical Investigation, Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA
    J Chromatogr A 1216:3533-7. 2009
    ....
  3. pmc Structural basis of G protein-coupled receptor-G protein interactions
    Jianxin Hu
    Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Nat Chem Biol 6:541-8. 2010
    ..As heterotrimeric G proteins as well as most GPCRs share a high degree of structural homology, our findings should be of broad general relevance...
  4. pmc Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells
    Wook Kim
    National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Diabetes 60:1198-209. 2011
    ..We undertook the current study to investigate if intraislet endogenous cannabinoids (ECs) regulate β-cell proliferation and if they influence insulin action...
  5. pmc Structural basis of toll-like receptor 3 signaling with double-stranded RNA
    Lin Liu
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Science 320:379-81. 2008
    ..This juxtaposition could mediate downstream signaling by dimerizing the cytoplasmic Toll interleukin-1 receptor (TIR) domains. The overall shape of the TLR3-ECD does not change upon binding to dsRNA...