Research Topics
| Xiao Yang WangSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survivalXiao Yang Wang
Department of Oncology, Georgetown University, and Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA
Mol Cancer 9:221. 2010..It is unknown how Msi1 relates to other breast cancer markers, whether it denotes tumor initiating cells (TICs), and how it affects gene expression and tumor cell survival in breast cancer cells...
Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathwaysXiao Yang Wang
Department of Oncology, Georgetown University, and Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA
Mol Cell Biol 28:3589-99. 2008..These results identify Msi1 as a key determinant of the mammary lineage through its ability to coordinate cell cycle entry and activate the Notch and Wnt pathways by a novel autocrine process involving PLF1 and DKK3...
Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokininAnandwardhan A Hardikar
Diabetes Transplant Unit, Prince of Wales Hospital and University of New South Wales, Sydney, New South Wales 2031, Australia
Endocrinology 143:3505-14. 2002..In conclusion, GLP-1 and CCK have a dual effect on fetal pig ICCs, causing maturation of glucose-induced insulin secretion from beta-cells as well as enhancement of differentiation from undifferentiated precursors...
Musashi1: a stem cell marker no longer in search of a functionRobert I Glazer
Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Cell Cycle 7:2635-9. 2008..Identification of PLF1 as an effector of these pathways in the absence of the DKK3 tumor suppressor provides a new avenue for investigating differences between normal and malignant tissues, and potentially targeting tumor stem cells...
