Lili Wang

Summary

Affiliation: National Institute of Standards and Technology
Country: USA

Publications

  1. ncbi request reprint Monoclonal antibody selection for interleukin-4 quantification using suspension arrays and forward-phase protein microarrays
    L Wang
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    J Proteome Res 6:4720-7. 2007
  2. doi request reprint Human CD4+ lymphocytes for antigen quantification: characterization using conventional flow cytometry and mass cytometry
    Lili Wang
    Biochemical Science Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA
    Cytometry A 81:567-75. 2012
  3. ncbi request reprint Raman and FTIR spectroscopies of fluorescein in solutions
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Spectrochim Acta A Mol Biomol Spectrosc 57:1781-91. 2001
  4. ncbi request reprint Fluorescent nanometer microspheres as a reporter for sensitive detection of simulants of biological threats using multiplexed suspension arrays
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Bioconjug Chem 16:194-9. 2005
  5. ncbi request reprint Spectroscopic characterization of fluorescein- and tetramethylrhodamine-labeled oligonucleotides and their complexes with a DNA template
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8312, Gaithersburg, MD 20899 8312, USA
    Spectrochim Acta A Mol Biomol Spectrosc 60:2741-50. 2004
  6. ncbi request reprint Comparison of ovalbumin quantification using forward-phase protein microarrays and suspension arrays
    L Wang
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    J Proteome Res 5:1770-5. 2006
  7. ncbi request reprint Comparison of fluorescein and phycoerythrin conjugates for quantifying CD20 expression on normal and leukemic B-cells
    Lili Wang
    Biochemical Science Division, National Institute of Standards and Technology NIST, Gaithersburg, Maryland 20899 8312, USA
    Cytometry B Clin Cytom 70:410-5. 2006
  8. ncbi request reprint Discrepancy in measuring CD4 expression on T-lymphocytes using fluorescein conjugates in comparison with unimolar CD4-phycoerythrin conjugates
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Cytometry B Clin Cytom 72:442-9. 2007
  9. ncbi request reprint Silicon nanoparticles as a luminescent label to DNA
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Bioconjug Chem 15:409-12. 2004
  10. ncbi request reprint Sensitivity comparison of real-time PCR probe designs on a model DNA plasmid
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Biochem 344:257-65. 2005

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Monoclonal antibody selection for interleukin-4 quantification using suspension arrays and forward-phase protein microarrays
    L Wang
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    J Proteome Res 6:4720-7. 2007
    ....
  2. doi request reprint Human CD4+ lymphocytes for antigen quantification: characterization using conventional flow cytometry and mass cytometry
    Lili Wang
    Biochemical Science Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA
    Cytometry A 81:567-75. 2012
    ..This study provides confirmation that the results obtained from the newly developed mass cytometry are directly comparable to the results from conventional flow cytometry when both methods are standardized using the same ABC approach...
  3. ncbi request reprint Raman and FTIR spectroscopies of fluorescein in solutions
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Spectrochim Acta A Mol Biomol Spectrosc 57:1781-91. 2001
    ..Excellent correlation is found between the experimental and calculated spectra...
  4. ncbi request reprint Fluorescent nanometer microspheres as a reporter for sensitive detection of simulants of biological threats using multiplexed suspension arrays
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Bioconjug Chem 16:194-9. 2005
    ..Importantly, the two simulants do not interfere with each other in the multiplexing experiments. The 40 nm FRET microspheres are a new sensitive alternative as fluorescent reporters for detection in suspension arrays...
  5. ncbi request reprint Spectroscopic characterization of fluorescein- and tetramethylrhodamine-labeled oligonucleotides and their complexes with a DNA template
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8312, Gaithersburg, MD 20899 8312, USA
    Spectrochim Acta A Mol Biomol Spectrosc 60:2741-50. 2004
    ..This interaction may bring the donor and the acceptor molecules closely together, which could cause interaction between the two dye molecules shown in absorbance measurements of the FRET complexes...
  6. ncbi request reprint Comparison of ovalbumin quantification using forward-phase protein microarrays and suspension arrays
    L Wang
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    J Proteome Res 5:1770-5. 2006
    ..Knowledge of the advantages and disadvantages of the two proteomic methods would allow their more rational use in clinical diagnosis...
  7. ncbi request reprint Comparison of fluorescein and phycoerythrin conjugates for quantifying CD20 expression on normal and leukemic B-cells
    Lili Wang
    Biochemical Science Division, National Institute of Standards and Technology NIST, Gaithersburg, Maryland 20899 8312, USA
    Cytometry B Clin Cytom 70:410-5. 2006
    ..CD20 expression in B-cell chronic lymphocytic leukemia (B-CLL) is one of the best examples of such a biomarker, but results from the use of different QFC methods vary considerably...
  8. ncbi request reprint Discrepancy in measuring CD4 expression on T-lymphocytes using fluorescein conjugates in comparison with unimolar CD4-phycoerythrin conjugates
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Cytometry B Clin Cytom 72:442-9. 2007
    ..We further examined pH of the cellular microenvironment as a cause of discordant results obtained with the FITC conjugate...
  9. ncbi request reprint Silicon nanoparticles as a luminescent label to DNA
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Bioconjug Chem 15:409-12. 2004
    ..We report a conjugation process that allows labeling of Si nanoparticles to an oligonucleotide in aqueous solutions. Ways to further optimize the procedure in order to achieve narrower and brighter photoluminescence are discussed...
  10. ncbi request reprint Sensitivity comparison of real-time PCR probe designs on a model DNA plasmid
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Biochem 344:257-65. 2005
    ..The study points out that the nucleotide environment surrounding the reporting fluorophore can strongly affect the probe performance in real-time PCR...
  11. ncbi request reprint Fluorescence resonance energy transfer between donor-acceptor pair on two oligonucleotides hybridized adjacently to DNA template
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8312, Gaithersburg, Maryland 20899 8312, USA
    Biopolymers 72:401-12. 2003
    ..The study identifies important parameters that determine FRET response in applications such as real-time PCR...
  12. doi request reprint Toward quantitative fluorescence measurements with multicolor flow cytometry
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Cytometry A 73:279-88. 2008
    ..The calibration procedure is based on firm scientific foundations so that it is easy to envision future improvements in accuracy and ease of implementation...
  13. doi request reprint NIST/ISAC standardization study: variability in assignment of intensity values to fluorescence standard beads and in cross calibration of standard beads to hard dyed beads
    Robert A Hoffman
    Biochemical Science Division, National Institute of Standards and Technology NIST, Gaithersburg, Maryland 20899 8312, USA
    Cytometry A 81:785-96. 2012
    ..Close interaction between bead manufacturers and NIST is recommended to have reliable and uniformly assigned fluorescence standard beads...
  14. ncbi request reprint Evaluating the quality of data from DNA microarray measurements
    Lili Wang
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD, USA
    Methods Mol Biol 381:121-31. 2007
    ..An array calibration slide was used to calibrate an Axon GenePix 4000A scanner and ensure the dynamic range of the instrument. The work is a first step toward our goal of quantitative gene expression measurements...
  15. ncbi request reprint A multistate model for the fluorescence response of R-phycoerythrin
    A Gaigalas
    National Institute of Standards and Technology, Gaithersburg, MD, USA
    Photochem Photobiol 82:635-44. 2006
    ..The two processes that result in the loss of fluorescence intensity are most likely associated with the PEB-560 group...
  16. ncbi request reprint Fluorescence resonance energy transfer-based method for detection of DNA binding activities of nuclear factor kappaB
    Hua Jun He
    National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Biotechniques 43:93-8. 2007
    ..In addition, this FRET-based assay can be easily adapted for high-throughput screening of NF-kappaB activation...
  17. doi request reprint An immunoprecipitation coupled with fluorescent Western blot analysis for the characterization of a model secondary serum cardiac troponin I reference material
    Hua Jun He
    Chemical Science and Technology Laboratory, National Institute of Standards and Technology NIST, Gaithersburg, MD 20899 8312, USA
    Clin Chim Acta 412:107-11. 2011
    ..The objective of this study is to develop measurement procedures for the characterization of the future secondary reference material using a pooled cTnI-positive serum sample as a development model...
  18. ncbi request reprint Photophysical properties of ricin
    A K Gaigalas
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD, USA
    Photochem Photobiol 83:1149-56. 2007
    ..Irreversible thermal unfolding of ricin occurred between 65 degrees C and 70 degrees C. (D=3.3364*10(-30) Cm, not SI unit, convenient unit for the magnitude of the electric dipole moment of molecules.)...
  19. doi request reprint Quantitative fluorescence measurements with multicolor flow cytometry
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, MD, USA
    Methods Mol Biol 699:53-65. 2011
    ..The chapter also points out current efforts for implementing quantification of biomarkers in a manner which is independent of instrument platforms and reagent differences...
  20. ncbi request reprint Application of electromodulated fluorescence to the study of the dynamics of single-strand oligonucleotides at modified gold surfaces
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA
    J Colloid Interface Sci 248:404-12. 2002
    ..Large variation in the EmF response was observed for electrodes modified with amine and carboxyl groups. This suggests that electrostatic interactions play a dominant role...
  21. doi request reprint Breast cancer biomarker measurements and standards
    Kenneth D Cole
    National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA
    Proteomics Clin Appl 7:17-29. 2013
    ..This review is focused on efforts to improve the quantitation and reliability of cancer biomarkers by using standards and reference materials...
  22. ncbi request reprint Optical properties of Alexa 488 and Cy5 immobilized on a glass surface
    Lili Wang
    National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Biotechniques 38:127-32. 2005
    ..These results suggest that the design of microarray detection systems should be based on the optical properties of fluorophores attached to the surface and not on the optical properties of fluorophores in solution...
  23. pmc Variables in the quantification of CD4 in normals and hairy cell leukemia patients
    Lili Wang
    Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8312, USA
    Cytometry B Clin Cytom 80:51-6. 2011
    ..Quantitative normal T-cell CD4 expression represents a biologic standard and quality control agent. However, low levels of CD4 expression were detected in normal T-cells in Hairy Cell Leukemia (HCL) samples...
  24. ncbi request reprint Particle concentration measurement of virus samples using electrospray differential mobility analysis and quantitative amino acid analysis
    Kenneth D Cole
    Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    J Chromatogr A 1216:5715-22. 2009
    ..The advantages and limitations of ES-DMA and AAA to characterize virus reference materials are discussed...
  25. pmc Sensing the insulin signaling pathway with an antibody array
    Hua Jun He
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD, USA
    Proteomics Clin Appl 3:1440-50. 2009
    ..Thus, this insulin signaling antibody array provides a powerful and effective way to investigate the mechanism of insulin resistance and likely assist the development of innovative therapeutic drugs for type 2 diabetes...
  26. ncbi request reprint Formalization of the MESF unit of fluorescence intensity
    Abe Schwartz
    Center for Quantitative Cytometry, San Juan, Puerto Rico
    Cytometry B Clin Cytom 57:1-6. 2004
    ..nist.gov) listed as the references 2-4. The use of the fluorescence intensity unit provides a tool to compare quantitative fluorescence intensity measurements over time and across platforms...
  27. ncbi request reprint The nitrate reductase gene-switch: a system for regulated expression in transformed cells of Dunaliella salina
    Jie Li
    Laboratory for Cell Biology, The First Affiliated Hospital, Zhengzhou University, Henan 450052, PR China
    Gene 403:132-42. 2007
    ..The findings of this study demonstrate that the promoter of the D. salina NR gene can be used to control expression of the heterologous genes in transgenic D. salina...
  28. ncbi request reprint Porous silicon biosensor for detection of viruses
    Andrea M Rossi
    Department of Electrical and Computer Engineering, University of Maryland, College Park, MD 20742, USA
    Biosens Bioelectron 23:741-5. 2007
    ..The system exhibits sensitivity and dynamic range similar to the Luminex liquid array-based assay while outperforming protein micro-array methods...
  29. ncbi request reprint Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid
    Luk H Vandenberghe
    Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 125 S 31st Street, Philadelphia, Pennsylvania 19104, USA
    Nat Med 12:967-71. 2006
    ..The role of heparin binding in the activation of CD8(+) T cells may be useful in modulating the immunogenicity of antigens and improving the safety profile of existing AAV vectors for gene therapy...
  30. ncbi request reprint Fabrication and experimental observation of monolithic multi-air-core fiber array for image transmission
    Jian Wang
    State Key Laboratory of Transient Optics and Photonics, Xi an Institute of Optics and Precision Mechanics, ChineseAcademy of Sciences, Information road 17, Xi an, Shannxi, 710119, China
    Opt Express 16:7703-8. 2008
    ..The imaging function of the fibers was investigated with home-made specialized microscopy. This new type of fiber provides strong potential for applications in endoscopy, chemical sensing, biosensors, fiber-optical faceplates...
  31. ncbi request reprint Intense ultraviolet upconversion luminescence from hexagonal NaYF4:Yb3+/Tm3+ microcrystals
    Guofeng Wang
    State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, P R China
    Opt Express 16:11907-14. 2008
    ..Theoretical analysis indicated that the complicated dependent relationships were mainly caused by phonon-assisted energy transfers and nonradiative relaxation...
  32. ncbi request reprint Solubilization and refolding with simultaneous purification of recombinant human stem cell factor
    Chaozhan Wang
    Institute of Modern Separation Science, Department of Chemistry, Northwest University, 229 Tai Bai North Road, Xi an 710069, People s Republic of China
    Appl Biochem Biotechnol 144:181-9. 2008
    ..It may have a great potential for large-scale production of rhSCF...
  33. ncbi request reprint S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase
    Robert Wuerffel
    Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL 60612 7344, USA
    Immunity 27:711-22. 2007
    ..Thus, the S-S synaptosome is formed as a result of the self-organizing transcription system that regulates GLT expression and may serve to guard against spurious chromosomal translocations...
  34. ncbi request reprint Development of a novel solid-phase extraction element for thermal desorption gas chromatography analysis
    Lili Wang
    Frontier Laboratories Ltd, Saikon 1 8 14, Koriyama, Fukushima 963 8862, Japan
    J Chromatogr A 1035:277-9. 2004
    ..992. Detection limit of 0.5 ng/l level was achieved and the reproducibility of the measurements for bethrodine at 10 ng/l level was found to be fairly good with relative standard deviation below 7.5%...
  35. ncbi request reprint Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms
    Emmanuel Planel
    Laboratory for Alzheimer s Disease, The Institute of Physical and Chemical Research, Saitama 351 0198, Japan
    J Neurosci 27:13635-48. 2007
    ....
  36. pmc Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney
    Hong Ming Shen
    Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA
    Mol Immunol 45:1883-92. 2008
    ..Despite this modification, known to enhance AID activity, resting B cells did not undergo SHM. Apparently, the large amounts of AID in resting B cells are not targeted to Ig genes in vivo, in contrast to findings in vitro...
  37. doi request reprint Chlorogenic acid derivatives with alkyl chains of different lengths and orientations: potent alpha-glucosidase inhibitors
    Chao Mei Ma
    Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930 0194, Japan
    J Med Chem 51:6188-94. 2008
    ..Acetals with the alkyl chain oriented toward position 2 of chlorogenic acid showed more potent activity than those oriented toward position 6...
  38. ncbi request reprint Structural and functional studies of the abundant tegument protein ORF52 from murine gammaherpesvirus 68
    Jordi Benach
    Department of Biological Sciences, Northeast Structural Genomics Consortium, Columbia University, New York, New York 10027, USA
    J Biol Chem 282:31534-41. 2007
    ..The results of the functional studies are fully consistent with the structural observations and indicate that the N-terminal alpha-helix is a crucial site of interaction for ORF52...
  39. ncbi request reprint Cloned endangered species takin (Budorcas taxicolor) by inter-species nuclear transfer and comparison of the blastocyst development with yak (Bos grunniens) and bovine
    Yanxin Li
    The State Key Laboratory of Agriobiotechnology, China Agricultural University, Yuanmingyuan West Road 2, Beijing, China
    Mol Reprod Dev 73:189-95. 2006
    ....
  40. ncbi request reprint [Effect of shenqi fuzheng injection on pre/post-operational change of argyrophilic-nucleolar organizer regions in peripheral T-lymphocyte in patients with gastric carcinoma]
    Jin quiang Yang
    The Third Department of Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang
    Zhongguo Zhong Xi Yi Jie He Za Zhi 25:626-8. 2005
    ..To investigate the pre-post operational change of argyrophilic-nucleolar organizer regions (Ag-NORs) in peripheral T-lymphocyte of patients with gastric carcinoma (GC), and to explore the effect of shenqi fuzheng injection(SFI) on it...
  41. ncbi request reprint No evidence for tumorigenesis of AAV vectors in a large-scale study in mice
    Peter Bell
    Gene Therapy Program, Division of Medical Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mol Ther 12:299-306. 2005
    ....
  42. ncbi request reprint T-cell specific enhancement of histone H3 acetylation in 5' flanking region of the IL-2 gene
    Lili Wang
    Department of Immunology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Biochem Biophys Res Commun 331:589-94. 2005
    ..These results suggest that the 5' flanking region including the distal enhancer region of the IL-2 gene is already accessible in T cells with constitutive acetylation of histone H3,which may serve for T-cell specific IL-2 expression...
  43. ncbi request reprint Birth of calves expressing the enhanced green fluorescent protein after transfer of fresh or vitrified/thawed blastocysts produced by somatic cell nuclear transfer
    Guochun Gong
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
    Mol Reprod Dev 69:278-88. 2004
    ..Our results show that genetic manipulation and serum starvation of donor cells (FOECs) do not affect in vitro developmental competence of bovine SCNT embryos, and vitrified transgenic SCNT blastocysts can develop to term successfully...
  44. ncbi request reprint Strategies for gene disruptions and plasmid constructions in fission yeast
    Lili Wang
    Boston College, Biology Department, Higgins Hall 401B, Chestnut Hill, MA 02467, USA
    Methods 33:199-205. 2004
    ..Several applications of this gap repair plasmid construction strategy are discussed...
  45. ncbi request reprint Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine heart: application to study of phospholamban physiology
    Hunter C Champion
    Division of Cardiology, Department of Medicine, 600 N Wolfe St, Halsted 500, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Circulation 108:2790-7. 2003
    ..We postulated that a key impediment derives from the use of proximal aortic occlusion during virus injection, because this eliminates coronary perfusion gradients in mice as aortic root and left ventricle pressures equalize...
  46. ncbi request reprint Increase of TCR V beta accessibility within E beta regulatory region influences its recombination frequency but not allelic exclusion
    Makoto Senoo
    Department of Immunology, Tokai University School of Medicine, Isehara, Kanagawa, Japan
    J Immunol 171:829-35. 2003
    ..These results provide strong evidence that increase of Vbeta accessibility influences frequency but not allelic exclusion of the TCR Vbeta rearrangement if the Vbeta gene is located in the Ebeta regulatory region...
  47. ncbi request reprint Genomewide screening of DNA copy number changes in chronic myelogenous leukemia with the use of high-resolution array-based comparative genomic hybridization
    Noriko Hosoya
    Department of Hematology and Oncology, Graduate School of Medicine, University of Tokyo, Hongo, Tokyo, Japan
    Genes Chromosomes Cancer 45:482-94. 2006
    ..This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  48. pmc Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase
    Richard S Kao
    Biology Department, Boston College, Chestnut Hill, Massachusetts 02467, USA
    Genetics 173:49-61. 2006
    ..In addition, Git1 and adenylate cyclase physically interact and partially colocalize in the cell. Thus, Git1 is a critical component of the S. pombe glucose/cAMP pathway...
  49. ncbi request reprint Renaturation with simultaneous purification of rhG-CSF from Escherichia coli by ion exchange chromatography
    Chaozhan Wang
    Institute of Modern Separation Science, Key Laboratory of Separation Science in Shaanxi Province, Department of Chemistry, Northwest University, Xi an, PR China
    Biomed Chromatogr 21:1291-6. 2007
    ..0 x 10(8) IU/mg, a purity of 96%, and a mass recovery of 49%. Compared with the usual dilution method, the IEC method developed here is more effective for rhG-CSF refolding in terms of specific bioactivity and mass recovery...
  50. ncbi request reprint NF-kappa B binds to the immunoglobulin S gamma 3 region in vivo during class switch recombination
    Lili Wang
    Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL 60612 7344, USA
    Eur J Immunol 36:3315-23. 2006
    ..H3 histone hyper acetylation at Sgamma1 is strongly correlated with NF-kappaB binding, suggesting that NF-kappaB mediates chromatin remodeling in the Sgamma3 and Sgamma1 region...
  51. pmc Streptococcus suis sequence type 7 outbreak, Sichuan, China
    Changyun Ye
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Changping, Beijing 102206, People s Republic of China
    Emerg Infect Dis 12:1203-8. 2006
    ..suis ST-7, the causative agent, was a single-locus variant of ST-1 with increased virulence. These findings strongly suggest that ST-7 is an emerging, highly virulent S. suis clone that caused the largest S. suis outbreak ever described...
  52. ncbi request reprint Preparation and physical characterization of a novel marine oil emulsion as a potential new formulation vehicle for lipid soluble drugs
    Guohui Cui
    School of Pharmacy, Memorial University of Newfoundland, St John s, Newfoundland, Canada A1B 3V6
    Int J Pharm 325:180-5. 2006
    ..It was shown that Crodasinic LS-30 had very little effect on the particle size, zeta-potential and pH, while the effect of Incroquat Benhenyl TMS was found to be dependent upon the concentration of the surfactant used...
  53. ncbi request reprint Expression of CD18 on the neutrophils of patients with diabetic retinopathy
    Huping Song
    Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University and Eye Institute of PLA, Xian 710032, People s Republic of China
    Graefes Arch Clin Exp Ophthalmol 245:24-31. 2007
    ..To investigate the expression of CD18 on neutrophils from patients with various stages of diabetic retinopathy (DR) and to determine the possibility of using it as a marker of disease development...
  54. ncbi request reprint FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates
    Liqin Zhao
    Laboratory of Computer Aided Drug Design and Discovery, Beijing Institute of Pharmacology and Toxicology, 27 Taiping Road, Beijing 100850, China
    J Med Chem 49:4059-71. 2006
    ..This study further suggests the clinical potential of novel FKBP ligands as a new therapeutic approach in the treatment of neurodegenerative disorders, such as Parkinson's disease...
  55. ncbi request reprint Modeling and synthesis of non-cyclic derivatives of GPI-1046 as potential FKBP ligands with neurotrophic properties
    Liqin Zhao
    Laboratory of Computer Aided Drug Design and Discovery, Beijing Institute of Pharmacology and Toxicology, Beijing, China
    Bioorg Med Chem Lett 16:4385-90. 2006
    ..However, in the absence of exogenously added NGF, all test compounds, including GPI-1046, failed to afford any positive effect on DRGs. This study suggests the intriguing potential of these compounds for further investigation...
  56. ncbi request reprint Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus
    Zhaoyang Zeng
    Cancer Research Institute, Central South University, Changsha 410078, Peoples Republic of China
    Genet Med 8:156-60. 2006
    ..In this study, family-based association analysis was performed to test the transmission disequilibrium of chromosome 3p in 18 high-risk nasopharyngeal carcinoma families of Hunan province in southern China...
  57. pmc Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
    Alberto Auricchio
    Institute for Human Gene Therapy, The Wistar Institute, Department of Medicine, and Division of Pulmonary Medicine, Department of Pediatrics, The Children s Hospital of Philadelphia and the University of Pennsylvania, Philadelphia 19104 4268, USA
    J Clin Invest 110:499-504. 2002
    ....