Research Topics
| P D WagnerSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Two-component kinase-like activity of nm23 correlates with its motility-suppressing activityP D Wagner
Laboratory of Biochemistry, Division of Basic Sciences, National Cancer Institute, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 94:9000-5. 1997..Thus, the transfer of phosphate from nm23-H1 to aspartates or glutamates on other proteins appears to correlate better with the suppression of motility than does the transfer to histidines...
Histidine to aspartate phosphotransferase activity of nm23 proteins: phosphorylation of aldolase C on Asp-319P D Wagner
Laboratory of Biochemistry, National Cancer Institute, Bethesda, MD 20892 4255, USA
Biochem J 346:623-30. 2000..The sequence around Asp-319 of aldolase C has some similarities to those around the histidine residues on ATP-citrate lyase and succinic thiokinase that are phosphorylated by nm23 proteins...
Phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins/nucleoside diphosphate kinasesP D Wagner
Laboratory of Biochemistry, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 275:35570-6. 2000..The phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins provides a novel mechanism by which these proteins might exert their biological effects...
Anti-(14-3-3 protein) antibody inhibits stimulation of noradrenaline (norepinephrine) secretion by chromaffin-cell cytosolic proteinsY N Wu
Laboratory of Biochemistry, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
Biochem J 285:697-700. 1992..These results demonstrate that 14-3-3 protein makes a significant contribution to the ability of leaked chromaffin-cell proteins to maintain secretory activity...
14-3-3 proteins bind to histone and affect both histone phosphorylation and dephosphorylationF Chen
Laboratory of Biochemistry, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
FEBS Lett 347:128-32. 1994..These results suggest that at least some of the reported effects of 14-3-3 proteins on PKC activity may result from 14-3-3 proteins binding to histone...
Pertussis toxin modification of PC12 cells lowers cytoskeletal F-actin and enhances norepinephrine secretion: involvement of protein kinase C and protein phosphatasesF Chen
Laboratory of Biochemistry, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Arch Physiol Biochem 105:317-28. 1998..The similarity between the effects of pertussis toxin and low concentrations of okadaic acid suggest that the effect of pertussis toxin on cytoskeletal F-actin in PC12 cells may result from an inhibition of protein phosphatase 2A...
