Research Topics
| Valerie VoonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Impulsive choice and response in dopamine agonist-related impulse control behaviorsValerie Voon
National Institutes of Health, 10 Center Drive, Bldg 10 Rm 7D37, Bethesda, MD 20892 1428, USA
Psychopharmacology (Berl) 207:645-59. 2010..Dopaminergic medication-related impulse control disorders (ICDs) such as pathological gambling and compulsive shopping have been reported in Parkinson's disease (PD)...
Medication-related impulse control and repetitive behaviors in Parkinson diseaseValerie Voon
National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr, Bldg 10, Room 5S213, Bethesda, MD 20892 1428, USA
Arch Neurol 64:1089-96. 2007..The study of these behaviors allows not only improved clinical management but also greater insight into a biologically mediated complex behavioral model...- Medication-related impulse control and repetitive behaviors in Parkinson's diseaseValerie Voon
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, Maryland 20892 1428, USA
Curr Opin Neurol 20:484-92. 2007..In patients on dopamine agonists, these behaviors as a group are relatively common, can have potentially devastating psychosocial consequences and are commonly hidden... - Factors associated with dopaminergic drug-related pathological gambling in Parkinson diseaseValerie Voon
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Arch Neurol 64:212-6. 2007..To evaluate factors associated with pathological gambling (PG) in Parkinson disease (PD)... 
Emotional stimuli and motor conversion disorderValerie Voon
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1428, USA
Brain 133:1526-36. 2010..Greater functional connectivity of limbic regions influencing motor preparatory regions during states of arousal may underlie the pathophysiology of motor conversion symptoms...- A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's diseaseValerie Voon
National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1428, USA
Brain 131:2720-8. 2008..Postoperative depression should be carefully assessed and treated. A multidisciplinary assessment and follow-up is recommended... - Prevalence of repetitive and reward-seeking behaviors in Parkinson diseaseV Voon
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1428, USA
Neurology 67:1254-7. 2006..4%. Compulsive shopping was 0.7%. Combined with our pathologic gambling data, the lifetime prevalence of these behaviors was 6.1% and increases to 13.7% in patients on dopamine agonists... - Deep brain stimulation: neuropsychological and neuropsychiatric issuesValerie Voon
Department of Psychiatry, Toronto Western Hospital, Toronto, Canada
Mov Disord 21:S305-27. 2006..Outcome studies, methodological issues, pathophysiology, and preoperative and postoperative management of the cognitive and neuropsychiatric aspects and complications of DBS for PD are discussed... - Prospective prevalence of pathologic gambling and medication association in Parkinson diseaseV Voon
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1428, USA
Neurology 66:1750-2. 2006..4% and on any dopamine agonist was 7.2%. PG was associated with earlier PD onset and with dopamine agonists but not with agonist subtype or doses. We found no association with a potent D3 receptor agonist... - Antidepressant treatment outcomes of psychogenic movement disorderValerie Voon
Department of Psychiatry, Toronto Western Hospital, Toronto, Ontario, Canada
J Clin Psychiatry 66:1529-34. 2005..Psychogenic movement disorder (PMD) is a subtype of conversion disorder. We describe the outcomes of a series of PMD patients following antidepressant treatment... - Deep brain stimulation: preoperative issuesAnthony E Lang
Department of Neurology, Toronto Western Hospital, Toronto, Ontario, Canada
Mov Disord 21:S171-96. 2006..It outlines answers to a series of questions developed to address all aspects of deep brain stimulation preoperative decision-making... - Psychiatric symptoms following surgery for Parkinson's disease with an emphasis on subthalamic stimulationValerie Voon
Department of Psychiatry, Toronto Western Hospital, UHN, Toronto, Canada
Adv Neurol 96:130-47. 2005..The paucity of the literature underscores the need for well-designed studies on psychiatric issues investigating both pathophysiology and clinical outcomes... - Mechanisms underlying dopamine-mediated reward bias in compulsive behaviorsValerie Voon
National Institutes of Health, Bethesda, MD 20892 1428, USA
Neuron 65:135-42. 2010..Thus, our findings are consistent with a model whereby a distorted estimation of the gain cue underpins a choice bias toward gains... - Amantadine use associated with impulse control disorders in Parkinson disease in cross-sectional studyDaniel Weintraub
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Ann Neurol 68:963-8. 2010..Further research, including larger clinical trials, is needed to assess the role of amantadine in the development and treatment of ICDs in PD... - Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's diseaseDaniel Weintraub
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Mov Disord 24:1461-7. 2009..A positive screen should be followed by a comprehensive, clinical interview to determine the range and severity of symptoms, as well as need for clinical management... - Psychiatric symptoms in patients with Parkinson disease presenting for deep brain stimulation surgeryValerie Voon
Department of Psychiatry, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
J Neurosurg 103:246-51. 2005..In the present study, preoperative psychiatric symptoms were systematically assessed in patients with PD presenting for routine preoperative psychiatric assessment... - Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's diseaseNaomi P Visanji
Toronto Western Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada
Mov Disord 21:1879-91. 2006..The response of different components of the psychotomimetic behavior suggested the involvement of both dopaminergic and nondopaminergic mechanisms in their expression... - Punding prevalence in Parkinson's diseaseJanis M Miyasaki
Movement Disorders Centre, Toronto Western Hospital, University Health Network, Krembil Neuroscience Centre, University of Toronto, Toronto, Canada
Mov Disord 22:1179-81. 2007..4%) in contrast with previous reports of 14%. Despite the low incidence, this behavior is disruptive and should be carefully elicited by physicians caring for Parkinson's disease patients... - Psychopathology and psychogenic movement disordersSarah Kranick
Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
Mov Disord 26:1844-50. 2011..A careful psychological assessment is indicated to optimize therapeutic modalities... - Antidepressants in the treatment of psychosis with comorbid depression in Parkinson diseaseValerie Voon
University of Toronto, Toronto Western Hospital University Health Network, Ontario, Canada
Clin Neuropharmacol 27:90-2. 2004..Potential mechanisms implicated in the response of psychosis to antidepressants are discussed... - Drug Insight: impulse control disorders and dopamine therapies in Parkinson's diseaseMarc N Potenza
Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
Nat Clin Pract Neurol 3:664-72. 2007.... - Deep brain stimulation for treatment-resistant depressionHelen S Mayberg
Rotman Research Institute at Baycrest Centre, and Departments of Psychiatry and Neurology, University of Toronto, Toronto, Ontario, M6A 2E1, Canada
Neuron 45:651-60. 2005.... - Diagnosis and treatment of impulse control disorders in patients with movement disordersTiago A Mestre
Movement Disorders Centre and the Edmond J Safra Program in Parkinson s Disease, Toronto Western Hospital, University Health Network, Division of Neurology, University of Toronto, Toronto, Ontario, Canada
Ther Adv Neurol Disord 6:175-88. 2013..Unfortunately, their use is only supported by case reports, small case series or open-label clinical studies. Prospective, controlled studies are warranted. Ongoing investigations include naltrexone and nicotine... - Psychogenic movement disorders: past developments, current status, and future directionsAnthony E Lang
Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Mov Disord 26:1175-86. 2011..Given the personal and societal impact of these problems, further advances in our understanding of their pathogenesis and the subsequent development of effective therapies are sorely needed... - Antidepressants and psychosis in Parkinson disease: a case seriesValerie Voon
Int J Geriatr Psychiatry 22:601-4. 2007 - Repetition, repetition, and repetition: compulsive and punding behaviors in Parkinson's diseaseValerie Voon
Mov Disord 19:367-70. 2004 - Pathological gambling in Parkinson's disease improves on chronic subthalamic nucleus stimulationClaire Ardouin
, CHU Grenoble, INSERM U318, , Grenoble, France
Mov Disord 21:1941-6. 2006.... - Dopamine receptor agonists and levodopa and inducing psychosis-like behavior in the MPTP primate model of Parkinson diseaseSusan H Fox
Arch Neurol 63:1343-4. 2006 - Deep brain stimulation: postoperative issuesGunther Deuschl
Department of Neurology, Christian Albrechts Universitat Kiel, Kiel, Germany
Mov Disord 21:S219-37. 2006..The report has been endorsed by the Scientific Issues Committee of the Movement Disorder Society and the American Society of Stereotactic and Functional Neurosurgery... - Diagnostic criteria for psychosis in Parkinson's disease: report of an NINDS, NIMH work groupBernard Ravina
Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14620, USA
Mov Disord 22:1061-8. 2007..These criteria require validation and may be refined, but form a starting point for studies of the epidemiology and pathophysiology of PDPsy, and are a potential indication for therapy development...