- Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cellsSuresh R Volate
Cancer Stem Cell Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute at Frederick, NIH, Frederick, Maryland 21702, USA
Mol Cancer Ther 9:461-70. 2010..These studies show for the first time that gossypol treatment induces DNA damage and activates p53. Collectively, these data support the use of gossypol as a novel agent for prostate cancer...