Cathy D Vocke

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors
    Cathy D Vocke
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:931-5. 2005
  2. pmc UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1107, Bldg 10 CRC, Room 1 5942, Bethesda, MD 20892 1107
    Cancer Genet Cytogenet 196:45-55. 2010
  3. doi request reprint Adrenal nodular hyperplasia in hereditary leiomyomatosis and renal cell cancer
    Brian Shuch
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1107, USA
    J Urol 189:430-5. 2013
  4. pmc The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 1W 5888, Bethesda, MD 20892, USA
    Cancer Genet Cytogenet 180:100-9. 2008
  5. pmc A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Genet 205:377-90. 2012
  6. pmc Hereditary kidney cancer: unique opportunity for disease-based therapy
    W Marston Linehan
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Building 10 CRC, Room 1 5940, Bethesda, MD 20892 1107, USA
    Cancer 115:2252-61. 2009
  7. pmc Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome
    Jihane N Benhammou
    Urologic Oncology Branch, NCI, NIH, Bethesda, MD 20892, USA
    Genes Chromosomes Cancer 50:466-77. 2011
  8. doi request reprint Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer
    Christopher J Ricketts
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Urol 188:2063-71. 2012
  9. ncbi request reprint Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer
    Jennifer I Swalwell
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892, USA
    Genes Chromosomes Cancer 33:201-5. 2002
  10. ncbi request reprint The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
    Igor Kuzmin
    Intramural Research Support Program, SAIC Frederick, Inc, National Cancer Institute Frederick, Maryland 21702, USA
    Cancer Res 62:3498-502. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors
    Cathy D Vocke
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:931-5. 2005
    ..These results support a role for BHD as a tumor suppressor gene that predisposes to the development of renal tumors when both copies are inactivated...
  2. pmc UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1107, Bldg 10 CRC, Room 1 5942, Bethesda, MD 20892 1107
    Cancer Genet Cytogenet 196:45-55. 2010
    ..This tumor model is the embodiment of the Warburg effect. UOK 262 provides a unique in vitro and in vivo preclinical model for studying the bioenergetics of the Warburg effect in human cancer...
  3. doi request reprint Adrenal nodular hyperplasia in hereditary leiomyomatosis and renal cell cancer
    Brian Shuch
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1107, USA
    J Urol 189:430-5. 2013
    ....
  4. pmc The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 1W 5888, Bethesda, MD 20892, USA
    Cancer Genet Cytogenet 180:100-9. 2008
    ..The result demonstrates that the established tumor cells consist of two cell populations, one containing four and one containing five copies of the MYC oncogene...
  5. pmc A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Genet 205:377-90. 2012
    ....
  6. pmc Hereditary kidney cancer: unique opportunity for disease-based therapy
    W Marston Linehan
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Building 10 CRC, Room 1 5940, Bethesda, MD 20892 1107, USA
    Cancer 115:2252-61. 2009
    ..Studies of the tricarboxylic acid cycle and the VHL-HIF pathways have provided the foundation for therapeutic approaches in patients with HLRCC-associated kidney cancer as well as other hereditary and sporadic forms of RCC...
  7. pmc Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome
    Jihane N Benhammou
    Urologic Oncology Branch, NCI, NIH, Bethesda, MD 20892, USA
    Genes Chromosomes Cancer 50:466-77. 2011
    ..RQ-PCR, MLPA and aCGH may be used for clinical molecular diagnosis of BHDS in patients who are FLCN mutation-negative by DNA sequencing...
  8. doi request reprint Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer
    Christopher J Ricketts
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Urol 188:2063-71. 2012
    ..We report our experience with the diagnosis, evaluation and treatment of this novel form of hereditary kidney cancer...
  9. ncbi request reprint Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer
    Jennifer I Swalwell
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892, USA
    Genes Chromosomes Cancer 33:201-5. 2002
    ..The three cases define an internally consistent minimal candidate tumor suppressor gene interval of approximately two megabases...
  10. ncbi request reprint The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
    Igor Kuzmin
    Intramural Research Support Program, SAIC Frederick, Inc, National Cancer Institute Frederick, Maryland 21702, USA
    Cancer Res 62:3498-502. 2002
    ..Suppression of cell growth in vitro was demonstrated after the reintroduction of RASSF1A-expressing construct into LNCaP prostate carcinoma cells. Our data implicate the RASSF1A gene in human prostate tumorigenesis...