M Verma

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The promise of biomarkers in cancer screening and detection
    Robert S Negm
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Trends Mol Med 8:288-93. 2002
  2. pmc Epigenome-Wide Association Studies (EWAS) in Cancer
    Mukesh Verma
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, Division of Epidemiology and Genetics, National Cancer Institute, National Institutes of Health NIH, 6130 Executive Boulevard, Suite 5100, Bethesda, MD 20892 7324, USA
    Curr Genomics 13:308-13. 2012
  3. doi request reprint Multiple infections and cancer: implications in epidemiology
    Vidya Vedham
    Methods and Technologies Branch, Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health NIH, 6130 Executive Boulevard, Suite 5100, Bethesda, MD 20892 7324, USA
    Technol Cancer Res Treat 13:177-94. 2014
  4. doi request reprint Cancer control and prevention: nutrition and epigenetics
    Mukesh Verma
    Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7324, USA
    Curr Opin Clin Nutr Metab Care 16:376-84. 2013
  5. pmc Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling
    Mukesh Verma
    Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:189-200. 2013
  6. pmc Cancer control and prevention by nutrition and epigenetic approaches
    Mukesh Verma
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Antioxid Redox Signal 17:355-64. 2012
  7. doi request reprint Epigenetic biomarkers in cancer epidemiology
    Mukesh Verma
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    Methods Mol Biol 863:467-80. 2012
  8. ncbi request reprint Epigenetics and cancer
    Mukesh Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7324, USA
    Crit Rev Clin Lab Sci 41:585-607. 2004
  9. ncbi request reprint Pancreatic cancer epidemiology
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20852, USA
    Technol Cancer Res Treat 4:295-301. 2005
  10. ncbi request reprint Genetic and epigenetic biomarkers in cancer : improving diagnosis, risk assessment, and disease stratification
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland 20852, USA
    Mol Diagn Ther 10:1-15. 2006

Collaborators

Detail Information

Publications34

  1. ncbi request reprint The promise of biomarkers in cancer screening and detection
    Robert S Negm
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Trends Mol Med 8:288-93. 2002
    ..Here, we discuss examples of recent advances and limitations in cancer biomarker identification and validation, and the implications for cancer prevention...
  2. pmc Epigenome-Wide Association Studies (EWAS) in Cancer
    Mukesh Verma
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, Division of Epidemiology and Genetics, National Cancer Institute, National Institutes of Health NIH, 6130 Executive Boulevard, Suite 5100, Bethesda, MD 20892 7324, USA
    Curr Genomics 13:308-13. 2012
    ..The current status of EWAS, challenges in the field, and their potential solutions are discussed in this article...
  3. doi request reprint Multiple infections and cancer: implications in epidemiology
    Vidya Vedham
    Methods and Technologies Branch, Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health NIH, 6130 Executive Boulevard, Suite 5100, Bethesda, MD 20892 7324, USA
    Technol Cancer Res Treat 13:177-94. 2014
    ..In this article, we discuss the role of infectious agents in malignancies, highlight the role of multiple/co-infections in cancer etiology, and review implications for cancer epidemiology...
  4. doi request reprint Cancer control and prevention: nutrition and epigenetics
    Mukesh Verma
    Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7324, USA
    Curr Opin Clin Nutr Metab Care 16:376-84. 2013
    ..To evaluate recent developments in nutritional epigenomics and related challenges, opportunities, and implications for cancer control and prevention...
  5. pmc Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling
    Mukesh Verma
    Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 22:189-200. 2013
    ..Rigorous analytic and validation standards, transparent availability of massive data, and integration in large-scale evidence are essential in fulfilling the potential of these technologies...
  6. pmc Cancer control and prevention by nutrition and epigenetic approaches
    Mukesh Verma
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Antioxid Redox Signal 17:355-64. 2012
    ..Epigenetics involves alterations in gene expression without changing the nucleotide sequence. Because some epigenetic changes can be reversed chemically, epigenetics has tremendous implications for disease intervention and treatment...
  7. doi request reprint Epigenetic biomarkers in cancer epidemiology
    Mukesh Verma
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    Methods Mol Biol 863:467-80. 2012
    ..This review discusses cancer biomarkers, the characteristics of an ideal biomarker for cancer, and technologies for biomarker detection...
  8. ncbi request reprint Epigenetics and cancer
    Mukesh Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7324, USA
    Crit Rev Clin Lab Sci 41:585-607. 2004
    ..Changes in gene expression due to epigenetic regulation can be reversed by chemicals, and this approach opens up a novel approach in cancer prevention and treatment...
  9. ncbi request reprint Pancreatic cancer epidemiology
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20852, USA
    Technol Cancer Res Treat 4:295-301. 2005
    ..Given current therapeutic modalities, only early detection of cancer of the pancreas, followed by surgical resection, offers the possibility of lengthening survival time...
  10. ncbi request reprint Genetic and epigenetic biomarkers in cancer : improving diagnosis, risk assessment, and disease stratification
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland 20852, USA
    Mol Diagn Ther 10:1-15. 2006
    ..The current status and the challenges in the field of genetic and epigenetic markers in cancer diagnosis, risk assessment, and disease stratification are discussed...
  11. ncbi request reprint Genetic and epigenetic biomarkers in cancer diagnosis and identifying high risk populations
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, United States
    Crit Rev Oncol Hematol 60:9-18. 2006
    ..In this review, the current status of the clinical genetic and epigenetic biomarkers and their implication in cancer diagnosis and risk assessment are discussed...
  12. ncbi request reprint Meeting report: mitochondrial DNA and cancer epidemiology
    Mukesh Verma
    Analytic Epidemiology Research Branch, National Cancer Institute, Rockville, Maryland 20852, USA
    Cancer Res 67:437-9. 2007
  13. ncbi request reprint Application of mitochondrial genome information in cancer epidemiology
    Mukesh Verma
    Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20852, USA
    Clin Chim Acta 383:41-50. 2007
    ..Applications of mitochondrial DNA markers to identify high risk populations and future challenges are discussed in this article...
  14. ncbi request reprint Biomarkers for risk assessment in molecular epidemiology of cancer
    M Verma
    Analytical Epidemiology Research Branch, Epidemiology and Genetics, Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
    Technol Cancer Res Treat 3:505-14. 2004
    ..The current challenges and future directions in the field are discussed in this article...
  15. ncbi request reprint MUC1 upregulation by ethanol
    M Verma
    Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
    Cancer Biochem Biophys 17:1-11. 1999
    ..This concentration of ethanol does not affect the half-life of MUC1 mRNA...
  16. ncbi request reprint Epigenetics in cancer: implications for early detection and prevention
    Mukesh Verma
    Cancer Biomarker Research Group, Division of Cancer Prevention, National Cancer Institute, MD 20892 7346, USA
    Lancet Oncol 3:755-63. 2002
    ..The discovery of these basic premises should stimulate much future research on epigenetics...
  17. ncbi request reprint Epigenetics in cancer prevention: early detection and risk assessment: introduction
    Barbara K Dunn
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Executive Plaza North, Rockville, Maryland 20852 7362, USA
    Ann N Y Acad Sci 983:1-4. 2003
  18. ncbi request reprint Viral genes and methylation
    Mukesh Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852 7362, USA
    Ann N Y Acad Sci 983:170-80. 2003
    ..Since methylation can be reversed by a variety of exogenous agents, great potential exists to develop interventions that target cancer-associated aberrant methylation in an effort to reverse or prevent carcinogenesis...
  19. ncbi request reprint Early detection and risk assessment: proceedings and recommendations from the Workshop on Epigenetics in Cancer Prevention
    Mukesh Verma
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Ann N Y Acad Sci 983:298-319. 2003
    ..Further research will lead to the identification of new targets for cancer prevention...
  20. ncbi request reprint Proteomic maps of the cancer-associated infectious agents
    Sudhir Srivastava
    Cancer Biomarkers Research Group, Analytical Epidemiology Branch, Organ System Branch, National Cancer Institute, Bethesda, MD 20892, USA
    J Proteome Res 4:1171-80. 2005
    ..Herein, we discuss the current technologies and challenges in the field, and application of protein signatures in cancer detection and prevention...
  21. ncbi request reprint Challenges for biomarkers in cancer detection
    Paul D Wagner
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7346, USA
    Ann N Y Acad Sci 1022:9-16. 2004
    ..Recent technological advances have helped develop noninvasive, sensitive, and specific biomarkers to detect cancer at early stages of the disease...
  22. ncbi request reprint Proteomics for cancer biomarker discovery
    Pothur R Srinivas
    Division of Cancer Prevention, National Cancer Institute, Rockville, MD 20852, USA
    Clin Chem 48:1160-9. 2002
    ..Finally, the review touches on the efforts of the Early Detection Research Network at the National Cancer Institute in promoting biomarker discovery for translation at the clinical level...
  23. ncbi request reprint Biomarkers for early detection of colon cancer
    S Srivastava
    Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland 20852, USA
    Clin Cancer Res 7:1118-26. 2001
    ....
  24. ncbi request reprint New cancer biomarkers deriving from NCI early detection research
    Mukesh Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institute of Health, 6130 Executive Boulevard, EPN 3142, Rockville, MD 20852 7346, USA
    Recent Results Cancer Res 163:72-84; discussion 264-6. 2003
    ..The network's serious determined efforts in linking discovery to process development, resulting in early detection tests and clinical assessment, are also discussed...
  25. ncbi request reprint Proteomic approaches within the NCI early detection research network for the discovery and identification of cancer biomarkers
    M Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA
    Ann N Y Acad Sci 945:103-15. 2001
    ..We highlight recent work from Network investigators to demonstrate the potential of proteomics to identify proteins present in cancer tissues and body fluids that are relevant for cancer screening...
  26. ncbi request reprint Proteomic analysis of cancer-cell mitochondria
    Mukesh Verma
    Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892, USA
    Nat Rev Cancer 3:789-95. 2003
    ....
  27. doi request reprint Proteomics and cancer epidemiology
    Mukesh Verma
    National Cancer Institute, Bethesda, MD, USA
    Methods Mol Biol 471:197-215. 2009
    ..Several markers have to be clinically validated. In this chapter, methods used in proteomic analysis of clinical samples, challenges in the proteomics and cancer epidemiology, and their potential solutions are discussed...
  28. ncbi request reprint Expression and methylation status of 14-3-3 sigma gene can characterize the different histological features of ovarian cancer
    Masanori Kaneuchi
    Department of Urology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, CA, USA
    Biochem Biophys Res Commun 316:1156-62. 2004
    ..This is the first report suggesting that 14-3-3 sigma gene expression and methylation status can characterize histological features of different types of ovarian cancer...
  29. ncbi request reprint WT1 and WT1-AS genes are inactivated by promoter methylation in ovarian clear cell adenocarcinoma
    Masanori Kaneuchi
    Department of Urology, University of California San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121, USA
    Cancer 104:1924-30. 2005
    ..The authors hypothesized that Wilms tumor suppressor 1 gene (WT1) sense and antisense (WT1-AS) expression and their promoter methylation status could characterize ovarian clear cell adenocarcinoma from ovarian serous adenocarcinoma...
  30. ncbi request reprint Application of nanotechnology in cancer
    Hirendra N Banerjee
    Department of Biological and Pharmaceutical Sciences, Elizabeth City State University, University of North Carolina, Elizabeth City, NC 27909, USA
    Technol Cancer Res Treat 7:149-54. 2008
    ..The implication of nanotechnology in cancer is discussed in this article with an emphasis on biomarker detection, imaging studies for diagnosis, and its role in therapeutic intervention...
  31. ncbi request reprint Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discovery
    Angelique H Habis
    Centers for Disease Control and Prevention, U S Public Health Service, U S Department of Health and Human Services, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 13:492-6. 2004
    ..However, with a sensitive gold particle-based detection method, reproducible microarray results were obtained using this RNA...
  32. ncbi request reprint Use of nanotechnology for the development of novel cancer biomarkers
    Hirendra Nath Banerjee
    University of North Carolina, Department of Biological Sciences and Pharmaceutical Sciences, Division of Mathematics, Sciences, Technology and Pharmaceutical Sciences, Elizabeth City, NC 27909, USA
    Expert Rev Mol Diagn 6:679-83. 2006
    ..Another area with near-term potential for the early detection of cancer is the identification of mutations and genomic instability...
  33. ncbi request reprint CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer
    Hideki Enokida
    Department of Urology, University of California, San Francisco, California 94121, USA
    Cancer Res 64:5956-62. 2004
    ..These findings suggest that CpG hypermethylation of MDR1 promoter is a frequent event in prostate cancer and is related to disease progression via increased cell proliferation in prostate cancer cells...