Research Topics
| M VermaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The promise of biomarkers in cancer screening and detectionRobert S Negm
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Trends Mol Med 8:288-93. 2002..Here, we discuss examples of recent advances and limitations in cancer biomarker identification and validation, and the implications for cancer prevention...
Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profilingMukesh Verma
Corresponding Author Mukesh Verma, Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, 6130 Executive Boulevard, Room 5100, Bethesda, MD 20892
Cancer Epidemiol Biomarkers Prev 22:189-200. 2013..Cancer Epidemiol Biomarkers Prev; 22(2); 189-200. ©2012 AACR...- Cancer control and prevention by nutrition and epigenetic approachesMukesh Verma
Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
Antioxid Redox Signal 17:355-64. 2012..Nutrients such as folic acid that supply methyl groups have been shown to have a protective effect in colon cancer... 
Epigenetic biomarkers in cancer epidemiologyMukesh Verma
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
Methods Mol Biol 863:467-80. 2012..This review discusses cancer biomarkers, the characteristics of an ideal biomarker for cancer, and technologies for biomarker detection...- Epigenetics and cancerMukesh Verma
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892 7324, USA
Crit Rev Clin Lab Sci 41:585-607. 2004..Changes in gene expression due to epigenetic regulation can be reversed by chemicals, and this approach opens up a novel approach in cancer prevention and treatment... - Pancreatic cancer epidemiologyMukesh Verma
Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20852, USA
Technol Cancer Res Treat 4:295-301. 2005..Given current therapeutic modalities, only early detection of cancer of the pancreas, followed by surgical resection, offers the possibility of lengthening survival time... - Genetic and epigenetic biomarkers in cancer : improving diagnosis, risk assessment, and disease stratificationMukesh Verma
Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland 20852, USA
Mol Diagn Ther 10:1-15. 2006..The current status and the challenges in the field of genetic and epigenetic markers in cancer diagnosis, risk assessment, and disease stratification are discussed... - Genetic and epigenetic biomarkers in cancer diagnosis and identifying high risk populationsMukesh Verma
Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, United States
Crit Rev Oncol Hematol 60:9-18. 2006..In this review, the current status of the clinical genetic and epigenetic biomarkers and their implication in cancer diagnosis and risk assessment are discussed... - Meeting report: mitochondrial DNA and cancer epidemiologyMukesh Verma
Analytic Epidemiology Research Branch, National Cancer Institute, Rockville, Maryland 20852, USA
Cancer Res 67:437-9. 2007 - Application of mitochondrial genome information in cancer epidemiologyMukesh Verma
Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20852, USA
Clin Chim Acta 383:41-50. 2007..Applications of mitochondrial DNA markers to identify high risk populations and future challenges are discussed in this article... - Biomarkers for risk assessment in molecular epidemiology of cancerM Verma
Analytical Epidemiology Research Branch, Epidemiology and Genetics, Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
Technol Cancer Res Treat 3:505-14. 2004..The current challenges and future directions in the field are discussed in this article... - MUC1 upregulation by ethanolM Verma
Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
Cancer Biochem Biophys 17:1-11. 1999..This concentration of ethanol does not affect the half-life of MUC1 mRNA... - Epigenetics in cancer: implications for early detection and preventionMukesh Verma
Cancer Biomarker Research Group, Division of Cancer Prevention, National Cancer Institute, MD 20892 7346, USA
Lancet Oncol 3:755-63. 2002..The discovery of these basic premises should stimulate much future research on epigenetics... - Epigenetics in cancer prevention: early detection and risk assessment: introductionBarbara K Dunn
Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Executive Plaza North, Rockville, Maryland 20852-7362, USA
Ann N Y Acad Sci 983:1-4. 2003 - Proteomic maps of the cancer-associated infectious agentsSudhir Srivastava
Cancer Biomarkers Research Group, Analytical Epidemiology Branch, Organ System Branch, National Cancer Institute, Bethesda, MD 20892, USA
J Proteome Res 4:1171-80. 2005..Herein, we discuss the current technologies and challenges in the field, and application of protein signatures in cancer detection and prevention... - Viral genes and methylationMukesh Verma
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852 7362, USA
Ann N Y Acad Sci 983:170-80. 2003..Since methylation can be reversed by a variety of exogenous agents, great potential exists to develop interventions that target cancer-associated aberrant methylation in an effort to reverse or prevent carcinogenesis... - Early detection and risk assessment: proceedings and recommendations from the Workshop on Epigenetics in Cancer PreventionMukesh Verma
Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Ann N Y Acad Sci 983:298-319. 2003..Further research will lead to the identification of new targets for cancer prevention... - Proteomics for cancer biomarker discoveryPothur R Srinivas
Division of Cancer Prevention, National Cancer Institute, Rockville, MD 20852, USA
Clin Chem 48:1160-9. 2002..Finally, the review touches on the efforts of the Early Detection Research Network at the National Cancer Institute in promoting biomarker discovery for translation at the clinical level... - Challenges for biomarkers in cancer detectionPaul D Wagner
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-7346, USA
Ann N Y Acad Sci 1022:9-16. 2004..Recent technological advances have helped develop noninvasive, sensitive, and specific biomarkers to detect cancer at early stages of the disease... - Biomarkers for early detection of colon cancerS Srivastava
Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland 20852, USA
Clin Cancer Res 7:1118-26. 2001.... - New cancer biomarkers deriving from NCI early detection researchMukesh Verma
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institute of Health, 6130 Executive Boulevard, EPN-3142, Rockville, MD 20852-7346, USA
Recent Results Cancer Res 163:72-84; discussion 264-6. 2003..The network's serious determined efforts in linking discovery to process development, resulting in early detection tests and clinical assessment, are also discussed... - Proteomic approaches within the NCI early detection research network for the discovery and identification of cancer biomarkersM Verma
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA
Ann N Y Acad Sci 945:103-15. 2001..We highlight recent work from Network investigators to demonstrate the potential of proteomics to identify proteins present in cancer tissues and body fluids that are relevant for cancer screening... - Proteomics and cancer epidemiologyMukesh Verma
National Cancer Institute, Bethesda, MD, USA
Methods Mol Biol 471:197-215. 2009..Several markers have to be clinically validated. In this chapter, methods used in proteomic analysis of clinical samples, challenges in the proteomics and cancer epidemiology, and their potential solutions are discussed... - Proteomic analysis of cancer-cell mitochondriaMukesh Verma
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892, USA
Nat Rev Cancer 3:789-95. 2003.... - Expression and methylation status of 14-3-3 sigma gene can characterize the different histological features of ovarian cancerMasanori Kaneuchi
Department of Urology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, CA, USA
Biochem Biophys Res Commun 316:1156-62. 2004..This is the first report suggesting that 14-3-3 sigma gene expression and methylation status can characterize histological features of different types of ovarian cancer... - Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discoveryAngelique H Habis
Centers for Disease Control and Prevention, U.S. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA, USA
Cancer Epidemiol Biomarkers Prev 13:492-6. 2004..However, with a sensitive gold particle-based detection method, reproducible microarray results were obtained using this RNA... - Use of nanotechnology for the development of novel cancer biomarkersHirendra Nath Banerjee
University of North Carolina, Department of Biological Sciences and Pharmaceutical Sciences, Division of Mathematics, Sciences, Technology and Pharmaceutical Sciences, Elizabeth City, NC 27909, USA
Expert Rev Mol Diagn 6:679-83. 2006..Another area with near-term potential for the early detection of cancer is the identification of mutations and genomic instability... - WT1 and WT1-AS genes are inactivated by promoter methylation in ovarian clear cell adenocarcinomaMasanori Kaneuchi
Department of Urology, University of California San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121, USA
Cancer 104:1924-30. 2005..This study presents new molecular characterizations between these two types of adenocarcinoma and may provide insight as to why clear cell adenocarcinoma has a poorer prognosis than serous adenocarcinoma of the ovary... - Application of nanotechnology in cancerHirendra N Banerjee
Department of Biological and Pharmaceutical Sciences, Elizabeth City State University, University of North Carolina, Elizabeth City, NC 27909, USA
Technol Cancer Res Treat 7:149-54. 2008..The implication of nanotechnology in cancer is discussed in this article with an emphasis on biomarker detection, imaging studies for diagnosis, and its role in therapeutic intervention... - CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancerHideki Enokida
Department of Urology, University of California, San Francisco, California 94121, USA
Cancer Res 64:5956-62. 2004..These findings suggest that CpG hypermethylation of MDR1 promoter is a frequent event in prostate cancer and is related to disease progression via increased cell proliferation in prostate cancer cells...