Research Topics
Species | Ivan VelascoSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
High extracellular gamma-aminobutyric acid protects cultured neurons against damage induced by the accumulation of endogenous extracellular glutamateIvan Velasco
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
J Neurosci Res 67:406-10. 2002....
Influence of serum-free medium on the expression of glutamate transporters and the susceptibility to glutamate toxicity in cultured cortical neuronsIvan Velasco
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
J Neurosci Res 71:811-8. 2003..We conclude that glutamate transporters with the culture conditions studied are sensitive to glutamate uptake inhibition and that Neurobasal/B27 medium protects cells against excitotoxicity...
Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cellsNéstor F Díaz
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
Int J Dev Neurosci 27:493-500. 2009..Our results suggest that estradiol should be useful in producing higher proportions of dopamine neurons from embryonic stem cells aimed for treating Parkinson's disease...
GABA effects during neuronal differentiation of stem cellsPatricia Salazar
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, AP 70 253, Mexico, DF, 04510, Mexico
Neurochem Res 33:1546-57. 2008..GABA effects in these cells are very similar to those found in embryonic cortical precursor cells, and therefore it is possible that this amino acid has important roles during adult brain plasticity...
Histamine induces neural stem cell proliferation and neuronal differentiation by activation of distinct histamine receptorsAnayansi Molina-Hernández
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
J Neurochem 106:706-17. 2008....
Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cellsGriselda Rodríguez-Martínez
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
PLoS ONE 7:e43797. 2012..Activin A is a protein that participates principally in reproductive functions. In the adult brain, Activin is neuroprotective, but its role in brain development is still elusive...
Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3CElisa Tamariz
Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico
J Neurosci Res 88:971-80. 2010..The observations reported here show phenotypic similarities between VM-TH(+) and ES-TH(+) neurons and suggest that semaphorins 3A and 3C could be employed to guide axons of grafted ES-TH(+) in therapeutic protocols for PD...
Activated Notch1 is a stronger astrocytic stimulus than leukemia inhibitory factor for rat neural stem cellsNidia S Rodríguez-Rivera
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico
Int J Dev Biol 53:947-53. 2009..These experiments show that cells stimulated with NICD differentiate more readily to astrocytes than LIF-treated NSC...
Therapeutic potential of motor neurons differentiated from embryonic stem cells and induced pluripotent stem cellsRodrigo López-González
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, DF, Mexico
Arch Med Res 43:1-10. 2012..This review summarizes MN differentiation protocols from ES and iPS cells in regard to neuronal differentiation efficiency, expression of MN markers and functional properties in vitro, as well as their therapeutic effects after grafting...
Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and developmentAlejandro López-Juárez
Instituto de Fisiologia Celular, Division de Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Glia 59:577-89. 2011..Altogether our data indicate that LPP3 participates in several aspects of neuron-glia communication required for proper cerebellum development...
Histamine up-regulates fibroblast growth factor receptor 1 and increases FOXP2 neurons in cultured neural precursors by histamine type 1 receptor activation: conceivable role of histamine in neurogenesis during cortical development in vivoAnayansi Molina-Hernández
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
Neural Dev 8:4. 2013....
Transient recovery in a rat model of familial amyotrophic lateral sclerosis after transplantation of motor neurons derived from mouse embryonic stem cellsRodrigo López-González
Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
Cell Transplant 18:1171-81. 2009..In contrast, WT rats analyzed at the same age possessed grafted GFP-positive MN in their spinal cords. These results strongly suggest that the transgenic hSOD1(G93A) environment is detrimental to grafted MN in the long term...
Progesterone and 17β-estradiol increase differentiation of mouse embryonic stem cells to motor neuronsRodrigo López-González
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico
IUBMB Life 63:930-9. 2011..Furthermore, the effect of estradiol was mediated by specific activation of ER-α...
Activin and TGF-β effects on brain development and neural stem cellsGriselda Rodríguez-Martínez
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
CNS Neurol Disord Drug Targets 11:844-55. 2012..The emerging picture from these studies suggests that these growth factors can be used to manipulate neurogenesis and might help to achieve restoration after brain deterioration...
Stem cells with neurogenic potential and steroid hormonesIvan Velasco
Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, AP 70 253, Mexico D F 04510, Mexico
Curr Top Med Chem 11:1684-93. 2011....
Changes in the content of estrogen alpha and progesterone receptors during differentiation of mouse embryonic stem cells to dopamine neuronsNéstor F Díaz
Departamento de Biologia, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
Brain Res Bull 73:75-80. 2007..These results show a differential expression pattern of ER-alpha and PR isoforms during neuronal differentiation of ESC...
