Ivan Velasco

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint High extracellular gamma-aminobutyric acid protects cultured neurons against damage induced by the accumulation of endogenous extracellular glutamate
    Ivan Velasco
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    J Neurosci Res 67:406-10. 2002
  2. ncbi request reprint Influence of serum-free medium on the expression of glutamate transporters and the susceptibility to glutamate toxicity in cultured cortical neurons
    Ivan Velasco
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    J Neurosci Res 71:811-8. 2003
  3. pmc Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells
    Néstor F Díaz
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Int J Dev Neurosci 27:493-500. 2009
  4. pmc Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons
    N Emmanuel Díaz-Martínez
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    Mol Ther 21:1579-91. 2013
  5. pmc Histamine up-regulates fibroblast growth factor receptor 1 and increases FOXP2 neurons in cultured neural precursors by histamine type 1 receptor activation: conceivable role of histamine in neurogenesis during cortical development in vivo
    Anayansi Molina-Hernández
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
    Neural Dev 8:4. 2013
  6. doi request reprint Progesterone and 17β-estradiol increase differentiation of mouse embryonic stem cells to motor neurons
    Rodrigo López-González
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico
    IUBMB Life 63:930-9. 2011
  7. doi request reprint Histamine induces neural stem cell proliferation and neuronal differentiation by activation of distinct histamine receptors
    Anayansi Molina-Hernández
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    J Neurochem 106:706-17. 2008
  8. doi request reprint GABA effects during neuronal differentiation of stem cells
    Patricia Salazar
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, AP 70 253, Mexico, DF, 04510, Mexico
    Neurochem Res 33:1546-57. 2008
  9. pmc Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells
    Griselda Rodríguez-Martínez
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    PLoS ONE 7:e43797. 2012
  10. pmc Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3C
    Elisa Tamariz
    Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico
    J Neurosci Res 88:971-80. 2010

Collaborators

Detail Information

Publications17

  1. ncbi request reprint High extracellular gamma-aminobutyric acid protects cultured neurons against damage induced by the accumulation of endogenous extracellular glutamate
    Ivan Velasco
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    J Neurosci Res 67:406-10. 2002
    ....
  2. ncbi request reprint Influence of serum-free medium on the expression of glutamate transporters and the susceptibility to glutamate toxicity in cultured cortical neurons
    Ivan Velasco
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    J Neurosci Res 71:811-8. 2003
    ..We conclude that glutamate transporters with the culture conditions studied are sensitive to glutamate uptake inhibition and that Neurobasal/B27 medium protects cells against excitotoxicity...
  3. pmc Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells
    Néstor F Díaz
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Int J Dev Neurosci 27:493-500. 2009
    ..Our results suggest that estradiol should be useful in producing higher proportions of dopamine neurons from embryonic stem cells aimed for treating Parkinson's disease...
  4. pmc Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons
    N Emmanuel Díaz-Martínez
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    Mol Ther 21:1579-91. 2013
    ..These results are evidence that Semaphorin 3-directed long-distance axonal growth of dopaminergic neurons, resulting in behavioral improvement, is possible in adult diseased brains. ..
  5. pmc Histamine up-regulates fibroblast growth factor receptor 1 and increases FOXP2 neurons in cultured neural precursors by histamine type 1 receptor activation: conceivable role of histamine in neurogenesis during cortical development in vivo
    Anayansi Molina-Hernández
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
    Neural Dev 8:4. 2013
    ....
  6. doi request reprint Progesterone and 17β-estradiol increase differentiation of mouse embryonic stem cells to motor neurons
    Rodrigo López-González
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico
    IUBMB Life 63:930-9. 2011
    ..Furthermore, the effect of estradiol was mediated by specific activation of ER-α...
  7. doi request reprint Histamine induces neural stem cell proliferation and neuronal differentiation by activation of distinct histamine receptors
    Anayansi Molina-Hernández
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    J Neurochem 106:706-17. 2008
    ....
  8. doi request reprint GABA effects during neuronal differentiation of stem cells
    Patricia Salazar
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, AP 70 253, Mexico, DF, 04510, Mexico
    Neurochem Res 33:1546-57. 2008
    ..GABA effects in these cells are very similar to those found in embryonic cortical precursor cells, and therefore it is possible that this amino acid has important roles during adult brain plasticity...
  9. pmc Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells
    Griselda Rodríguez-Martínez
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    PLoS ONE 7:e43797. 2012
    ..Activin A is a protein that participates principally in reproductive functions. In the adult brain, Activin is neuroprotective, but its role in brain development is still elusive...
  10. pmc Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3C
    Elisa Tamariz
    Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico
    J Neurosci Res 88:971-80. 2010
    ..The observations reported here show phenotypic similarities between VM-TH(+) and ES-TH(+) neurons and suggest that semaphorins 3A and 3C could be employed to guide axons of grafted ES-TH(+) in therapeutic protocols for PD...
  11. doi request reprint Activated Notch1 is a stronger astrocytic stimulus than leukemia inhibitory factor for rat neural stem cells
    Nidia S Rodríguez-Rivera
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico
    Int J Dev Biol 53:947-53. 2009
    ..These experiments show that cells stimulated with NICD differentiate more readily to astrocytes than LIF-treated NSC...
  12. doi request reprint Therapeutic potential of motor neurons differentiated from embryonic stem cells and induced pluripotent stem cells
    Rodrigo López-González
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, DF, Mexico
    Arch Med Res 43:1-10. 2012
    ..This review summarizes MN differentiation protocols from ES and iPS cells in regard to neuronal differentiation efficiency, expression of MN markers and functional properties in vitro, as well as their therapeutic effects after grafting...
  13. pmc Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development
    Alejandro López-Juárez
    Instituto de Fisiologia Celular, Division de Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Glia 59:577-89. 2011
    ..Altogether our data indicate that LPP3 participates in several aspects of neuron-glia communication required for proper cerebellum development...
  14. ncbi request reprint Activin and TGF-β effects on brain development and neural stem cells
    Griselda Rodríguez-Martínez
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    CNS Neurol Disord Drug Targets 11:844-55. 2012
    ..The emerging picture from these studies suggests that these growth factors can be used to manipulate neurogenesis and might help to achieve restoration after brain deterioration...
  15. doi request reprint Transient recovery in a rat model of familial amyotrophic lateral sclerosis after transplantation of motor neurons derived from mouse embryonic stem cells
    Rodrigo López-González
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Cell Transplant 18:1171-81. 2009
    ..In contrast, WT rats analyzed at the same age possessed grafted GFP-positive MN in their spinal cords. These results strongly suggest that the transgenic hSOD1(G93A) environment is detrimental to grafted MN in the long term...
  16. pmc Changes in the content of estrogen alpha and progesterone receptors during differentiation of mouse embryonic stem cells to dopamine neurons
    Néstor F Díaz
    Departamento de Biologia, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
    Brain Res Bull 73:75-80. 2007
    ..These results show a differential expression pattern of ER-alpha and PR isoforms during neuronal differentiation of ESC...
  17. ncbi request reprint Stem cells with neurogenic potential and steroid hormones
    Ivan Velasco
    Instituto de Fisiologia Celular Neurociencias, Universidad Nacional Autonoma de Mexico, AP 70 253, Mexico D F 04510, Mexico
    Curr Top Med Chem 11:1684-93. 2011
    ....