M P Vawter

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Dysregulation of the neural cell adhesion molecule and neuropsychiatric disorders
    M P Vawter
    National Institute on Drug Abuse IRP NIDA IRP, Addiction Research Center, Section on Development and Plasticity, Baltimore, MD 21224, USA
    Eur J Pharmacol 405:385-95. 2000
  2. ncbi request reprint Elevated concentration of N-CAM VASE isoforms in schizophrenia
    M P Vawter
    Cellular Neurobiology Branch, NIDA IRP, Baltimore, MD 21224, USA
    J Psychiatr Res 34:25-34. 2000
  3. ncbi request reprint The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia
    E Lehrmann
    Cellular Neurobiology Research Branch, National Institute on Drug Abuse, NIH DHHS, Baltimore, MD 21224, USA
    Curr Mol Med 3:437-46. 2003
  4. ncbi request reprint Application of cDNA microarrays to examine gene expression differences in schizophrenia
    M P Vawter
    Section on Plasticity and Development, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
    Brain Res Bull 55:641-50. 2001
  5. ncbi request reprint Assembly and use of a broadly applicable neural cDNA microarray
    T Barrett
    Transgenic and Knockout Facility Section, National Institute on Aging, NIH, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Restor Neurol Neurosci 18:127-35. 2001
  6. ncbi request reprint Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia
    M P Vawter
    Cellular Neurobiology Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Psychiatry 7:571-8. 2002
  7. ncbi request reprint Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells
    M E Truckenmiller
    Cellular Neurobiology Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Restor Neurol Neurosci 18:67-80. 2001
  8. pmc Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse
    E Lehrmann
    Cellular Neurobiology Research Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
    Pharmacogenomics J 3:27-40. 2003
  9. ncbi request reprint A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity
    T Barrett
    Research Resources Branch, Laboratory of Genetics, Intramural Research Program, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, Maryland 21224-6825, USA
    Neurobiol Dis 8:822-33. 2001
  10. ncbi request reprint Characterization of human cleaved N-CAM and association with schizophrenia
    M P Vawter
    Development and Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    Exp Neurol 172:29-46. 2001

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Dysregulation of the neural cell adhesion molecule and neuropsychiatric disorders
    M P Vawter
    National Institute on Drug Abuse IRP NIDA IRP, Addiction Research Center, Section on Development and Plasticity, Baltimore, MD 21224, USA
    Eur J Pharmacol 405:385-95. 2000
    ..Synapse stability and plasticity may be part of the molecular neuropathology of these disorders...
  2. ncbi request reprint Elevated concentration of N-CAM VASE isoforms in schizophrenia
    M P Vawter
    Cellular Neurobiology Branch, NIDA IRP, Baltimore, MD 21224, USA
    J Psychiatr Res 34:25-34. 2000
    ..These results provide further evidence of an abnormality of N-CAM protein in chronic schizophrenia and suggest differences between schizophrenia and affective disorders in regulation of N-CAM...
  3. ncbi request reprint The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia
    E Lehrmann
    Cellular Neurobiology Research Branch, National Institute on Drug Abuse, NIH DHHS, Baltimore, MD 21224, USA
    Curr Mol Med 3:437-46. 2003
    ....
  4. ncbi request reprint Application of cDNA microarrays to examine gene expression differences in schizophrenia
    M P Vawter
    Section on Plasticity and Development, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
    Brain Res Bull 55:641-50. 2001
    ..Identification of patterns of changes in gene expression may lead to a better understanding of the pathophysiology of schizophrenia disorders...
  5. ncbi request reprint Assembly and use of a broadly applicable neural cDNA microarray
    T Barrett
    Transgenic and Knockout Facility Section, National Institute on Aging, NIH, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Restor Neurol Neurosci 18:127-35. 2001
    ..This selected set of brain-relevant cDNAs should be widely useful in the analysis of gene expression patterns from brain tissues as well as neural cell lines...
  6. ncbi request reprint Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia
    M P Vawter
    Cellular Neurobiology Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Psychiatry 7:571-8. 2002
    ..Reductions in synapsin in both patients with schizophrenia (synapsin IIa and IIIa) and bipolar disorder (synapsin Ia, IIa and IIIa) imply that altered or reduced synaptic function in the hippocampus may be involved in these disorders...
  7. ncbi request reprint Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells
    M E Truckenmiller
    Cellular Neurobiology Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Restor Neurol Neurosci 18:67-80. 2001
    ..We employed a broad human 15K microarray (15,000 genes) and focused Neuroarray (1152 genes) to examine changes in gene expression early in the process of differentiation (6 hr), before morphology or growth changes are observed...
  8. pmc Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse
    E Lehrmann
    Cellular Neurobiology Research Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
    Pharmacogenomics J 3:27-40. 2003
    ..These data suggest that cocaine abuse targets a distinct subset of genes in the dlPFC, resulting in either a state of acute activation in which increased gene expression predominates, or a relatively destimulated, refractory phase...
  9. ncbi request reprint A murine dopamine neuron-specific cDNA library and microarray: increased COX1 expression during methamphetamine neurotoxicity
    T Barrett
    Research Resources Branch, Laboratory of Genetics, Intramural Research Program, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, Maryland 21224-6825, USA
    Neurobiol Dis 8:822-33. 2001
    ..This is the first work to describe a gene expression profile for a neuronal subtype and to identify gene expression changes during methamphetamine neurotoxicity...
  10. ncbi request reprint Characterization of human cleaved N-CAM and association with schizophrenia
    M P Vawter
    Development and Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    Exp Neurol 172:29-46. 2001
    ..Alternatively, the increases in cN-CAM in schizophrenia may be a reflection of a more general abnormality in the regulation of proteolysis or of extracellular matrix stability...
  11. pmc Region-specific transcriptional response to chronic nicotine in rat brain
    - Konu O
    Department of Pharmacology, University of Tennessee College of Medicine, 874 Union Avenue, Memphis, TN 38163, USA
    Brain Res 909:194-203. 2001
    ..Finally, a number of genes, involved in MAPK, phosphatidylinositol, and EGFR signaling pathways, were identified and proposed as possible targets in response to nicotine administration...
  12. pmc DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles
    S J Evans
    Pritzker Consortium for Severe Psychiatric Disorders, San Francisco, CA, USA
    Neurobiol Dis 14:240-50. 2003
    ....
  13. pmc Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders
    M P Vawter
    Department of Psychiatry, University of California, Irvine, USA
    Mol Psychiatry 11:615, 663-79. 2006
    ..Genes with the least sensitivity to agonal-pH could present a starting point for candidate gene search in neuropsychiatric disorders...
  14. pmc Dysregulation of the fibroblast growth factor system in major depression
    S J Evans
    Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 101:15506-11. 2004
    ..We also make available the gene-expression profile of all of the other growth factors and growth factor receptors detected in these postmortem samples...
  15. pmc Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression
    P V Choudary
    Center for Neuroscience and Department of Psychiatry and Behavioral Sciences, University of California Davis, 1544 Newton Court, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 102:15653-8. 2005
    ..These findings point to previously undiscovered molecular underpinnings of the pathophysiology of major depression and offer potentially new pharmacological targets for treating depression...
  16. pmc Coding SNPs included in exon arrays for the study of psychiatric disorders
    A Sequeira
    Mol Psychiatry 13:363-5. 2008