Que N Van

Summary

Affiliation: National Cancer Institute
Country: USA

Publications

  1. doi request reprint Analytical and statistical approaches to metabolomics research
    Haleem J Issaq
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    J Sep Sci 32:2183-99. 2009
  2. ncbi request reprint Comparison of 1D and 2D NMR spectroscopy for metabolic profiling
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA
    J Proteome Res 7:630-9. 2008
  3. ncbi request reprint The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    Dis Markers 19:169-83. 2003
  4. doi request reprint Metabolic profiling for the detection of bladder cancer
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, MD 21702, USA
    Curr Urol Rep 12:34-40. 2011
  5. ncbi request reprint The depletion of protein signals in metabonomics analysis with the WET-CPMG pulse sequence
    Que N Van
    SAIC Frederick, Inc, National Cancer Institute at Frederick, P O Box B, Bldg 469, Rm 160, Frederick, MD 21702, USA
    Biochem Biophys Res Commun 301:952-9. 2003
  6. pmc Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2'-exo (north) and 3'-exo (south) 'locked' templates
    Melissa Maderia
    Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA
    Nucleic Acids Res 35:1978-91. 2007
  7. pmc How close is the bench to the bedside? Metabolic profiling in cancer research
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, USA
    Genome Med 1:5. 2009
  8. pmc Schweinfurthins I and J from Macaranga schweinfurthii
    Paul Klausmeyer
    Natural Products Support Group, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland 21702, USA
    J Nat Prod 73:479-81. 2010
  9. ncbi request reprint Application of high-field NMR and cryogenic probe technologies in the structural elucidation of poecillastrin a, a new antitumor macrolide lactam from the sponge poecillastra species
    Mohammad A Rashid
    Molecular Targets Drug Discovery Program, Center for Cancer Research, National Cancer Institute, Building 1052, Room 121, Frederick, Maryland 21702 1201, USA
    Org Lett 4:3293-6. 2002

Collaborators

Detail Information

Publications9

  1. doi request reprint Analytical and statistical approaches to metabolomics research
    Haleem J Issaq
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    J Sep Sci 32:2183-99. 2009
    ....
  2. ncbi request reprint Comparison of 1D and 2D NMR spectroscopy for metabolic profiling
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA
    J Proteome Res 7:630-9. 2008
    ..While acquisition of the 2D data require more time, the data obtained resulted in a more meaningful and comprehensive metabolic profile, aided in metabolite identifications, and minimized ambiguities in peak assignments...
  3. ncbi request reprint The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    Dis Markers 19:169-83. 2003
    ..Using this bioinformatic approach, we were able to discriminate spectral patterns associated with IC-affected, BC-affected, and unaffected patients with a success rate of approximately 84%...
  4. doi request reprint Metabolic profiling for the detection of bladder cancer
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, MD 21702, USA
    Curr Urol Rep 12:34-40. 2011
    ....
  5. ncbi request reprint The depletion of protein signals in metabonomics analysis with the WET-CPMG pulse sequence
    Que N Van
    SAIC Frederick, Inc, National Cancer Institute at Frederick, P O Box B, Bldg 469, Rm 160, Frederick, MD 21702, USA
    Biochem Biophys Res Commun 301:952-9. 2003
    ....
  6. pmc Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2'-exo (north) and 3'-exo (south) 'locked' templates
    Melissa Maderia
    Laboratory of Medicinal Chemistry, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA
    Nucleic Acids Res 35:1978-91. 2007
    ..Our data and those of others suggest that although DNA can tolerate modifications with RNA-like (North) nucleotides, a more complicated spectrum of changes emerges with modifications restricted to South (DNA-like) puckers...
  7. pmc How close is the bench to the bedside? Metabolic profiling in cancer research
    Que N Van
    Laboratory of Proteomics and Analytical Technologies, Advanced Technology Program, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, USA
    Genome Med 1:5. 2009
    ..Here, we discuss the challenges and opportunities in metabolic phenotyping for discovering novel cancer biomarkers, and we assess the clinical applicability of MS and NMR...
  8. pmc Schweinfurthins I and J from Macaranga schweinfurthii
    Paul Klausmeyer
    Natural Products Support Group, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland 21702, USA
    J Nat Prod 73:479-81. 2010
    ..The structures of these new compounds, schweinfurthins I and J (1 and 2), were elucidated by 1D- and 2D-NMR techniques...
  9. ncbi request reprint Application of high-field NMR and cryogenic probe technologies in the structural elucidation of poecillastrin a, a new antitumor macrolide lactam from the sponge poecillastra species
    Mohammad A Rashid
    Molecular Targets Drug Discovery Program, Center for Cancer Research, National Cancer Institute, Building 1052, Room 121, Frederick, Maryland 21702 1201, USA
    Org Lett 4:3293-6. 2002
    ..The structure of poecillastrin A (1) was assigned using NMR data acquired at 500 MHz with an inverse-detection cryogenic probe and at 800 MHz with a room-temperature probe...