Research Topics
| P M ValloneSummaryAffiliation: National Institute of Standards and Technology Country: USA Publications
| Collaborators
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Detail Information
Publications
High-throughput Y-STR typing of U.S. populations with 27 regions of the Y chromosome using two multiplex PCR assaysRichard Schoske
Biotechnology Division, National Institute of Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899, USA
Forensic Sci Int 139:107-21. 2004..Samples containing the most common type in the European database could be well resolved with additional markers beyond the minimal haplotype loci...
Capillary electrophoresis of an 11-plex mtDNA coding region SNP single base extension assay for discrimination of the most common Caucasian HV1/HV2 mitotypePeter M Vallone
Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD, USA
Methods Mol Biol 830:159-67. 2012..Separation and detection can be accomplished with a capillary-based electrophoresis platform commonly found in most forensic laboratories...- Forensic application of the Affymetrix human mitochondrial resequencing arrayP M Vallone
National Institute of Standards and Technology NIST, Biochemical Sciences Division, 100 Bureau Dr, M S 8311, Gaithersburg, MD 20899 8311, United States
Forensic Sci Int Genet 1:196-8. 2007..Here we evaluate the potential of the Affymetrix GeneChip Mitochondrial Resequencing Array (version 2.0) for forensic applications... - Allele frequencies for 70 autosomal SNP loci with U.S. Caucasian, African-American, and Hispanic samplesPeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8311, USA
Forensic Sci Int 149:279-86. 2005..The final pair of unrelated samples could be resolved with the combination of 4 STR loci: D2S1338, D18S51, FGA, and VWA... - AutoDimer: a screening tool for primer-dimer and hairpin structuresPeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
Biotechniques 37:226-31. 2004..Sodium counterion and total stand concentrations can be adjusted for the Tm and deltaG calculations. The predicted interactions are saved in a text file for further evaluation... - A multiplex allele-specific primer extension assay for forensically informative SNPs distributed throughout the mitochondrial genomePeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899, USA
Int J Legal Med 118:147-57. 2004..We demonstrate that the assay performs well for heteroplasmy and mixture detection, and for typical mtDNA casework samples with highly degraded DNA... - A strategy for examining complex mixtures of deoxyoligonucleotides using ion-pair-reverse-phase high-performance liquid chromatography, matrix-assisted laser desorption ionization time-of-flight mass spectrometry, and informaticsPeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899, USA
Anal Biochem 304:257-65. 2002..IP-RP HPLC, MALDI-TOF MS, exonuclease digests, and a simple computational algorithm provide an integrated strategy for determining the sequence of short nucleic acid oligomers... - Genotyping of two mutations in the HFE gene using single-base extension and high-performance liquid chromatographyJ M Devaney
Transgenomic Inc, Gaithersburg, Maryland 20878, USA
Anal Chem 73:620-4. 2001..This assay allows concurrent genotyping of the C282Y and H63D mutations in 11 min and is 100% concordant with current testing methods for both of these mutations... - Capillary electrophoresis as a tool for optimization of multiplex PCR reactionsJ M Butler
National Institute of Standards and Technology, Biotechnology Division, Gaithersburg, MD 20899, USA
Fresenius J Anal Chem 369:200-5. 2001..The rapid separation and quantitation capabilities of capillary electrophoresis make it an efficient technique to help in the multiplex PCR optimization process... - Quality control of PCR primers used in multiplex STR amplification reactionsJ M Butler
Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899, USA
Forensic Sci Int 119:87-96. 2001..We present here the use of high performance liquid chromatography (HPLC) and time-of-flight mass spectrometry (TOF-MS) methods for characterization of commercially available STR kits... - The impact of additional Y-STR loci on resolving common haplotypes and closely related individualsA E Decker
National Institute of Standards and Technology, Biochemical Science Division, Gaithersburg, MD 20899, United States
Forensic Sci Int Genet 1:215-7. 2007..S. population groups. Additional Y-STRs can also increase the power of discrimination between closely related male individuals, which is important not only in forensics but also in the paternity and genetic genealogy communities... - Demonstration of rapid multiplex PCR amplification involving 16 genetic lociPeter M Vallone
National Institute of Standards and Technology, Biochemical Science Division, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899 8311, USA
Forensic Sci Int Genet 3:42-5. 2008..84... - Production and certification of NIST Standard Reference Material 2372 Human DNA Quantitation StandardMargaret C Kline
Biochemical Science Division, National Institute of Standards and Technology, 100 Bureau Drive, MS 8311, Gaithersburg, MD 20899 8311, USA
Anal Bioanal Chem 394:1183-92. 2009.... - A 26plex autosomal STR assay to aid human identity testing*Carolyn R Hill
Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8311, USA
J Forensic Sci 54:1008-15. 2009..The 26plex has the potential to benefit the forensic community for reference sample testing and complex relationship evaluation... - Allele frequencies for 27 Y-STR loci with U.S. Caucasian, African American, and Hispanic samplesJohn M Butler
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8311, USA
Forensic Sci Int 156:250-60. 2006..Allele frequencies for each locus are reported along with nomenclature based on sequence analysis... - Effective strategies for forensic analysis in the mitochondrial DNA coding regionMichael D Coble
Biotechnology Division, National Institute of Standards and Technology, 100Bureau Drive Mail Stop 8311, Gaithersburg, MD 20899, USA
Int J Legal Med 120:27-32. 2006..This is true even when only synonymous variation is targeted to minimize the potential for problems arising from discovery of mutations that have reportedly been related to disease... - Chromosomal duplications along the Y-chromosome and their potential impact on Y-STR interpretationJohn M Butler
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
J Forensic Sci 50:853-9. 2005..In addition, duplicated loci typically possess alleles that differ by only a single repeat unit and possess similar peak heights... - Mitochondrial DNA typing screens with control region and coding region SNPsMargaret C Kline
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
J Forensic Sci 50:377-85. 2005..These types of screening assays should enable more rapid evaluation of forensic casework samples such that only samples not excluded would be subjected to further characterization through full HVI/HVII mtDNA sequence analysis... - Y-SNP typing of U.S. African American and Caucasian samples using allele-specific hybridization and primer extensionPeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8311, USA
J Forensic Sci 49:723-32. 2004..A total of 18 unique haplogroups out of a possible 45 were observed in a group of 229 U.S. African American and Caucasian males with the majority of samples being assigned into 2 of the 18 haplogroups... - A novel multiplex for simultaneous amplification of 20 Y chromosome STR markersJohn M Butler
Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8311, Gaithersburg, MD 20899, USA
Forensic Sci Int 129:10-24. 2002..Haplotype comparisons between the 20plex and a commercially available kit found excellent agreement across the 76 samples in the Y chromosome consortium panel... - Allele frequencies for 15 autosomal STR loci on U.S. Caucasian, African American, and Hispanic populationsJohn M Butler
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8311, USA
J Forensic Sci 48:908-11. 2003 - Genotyping SNPs using a UV-photocleavable oligonucleotide in MALDI-TOF MSPeter M Vallone
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD, USA
Methods Mol Biol 297:169-78. 2005..Subsequently, the small fragments derived from the 3' ends of the molecules containing the genotype information were analyzed by matrix-assisted laser desorption ionization time-of-flight using a 3-hydroxypicolinic acid matrix... - Toward increased utility of mtDNA in forensic identificationsRebecca S Just
Armed Forces DNA Identification Laboratory, Armed Forces Institute of Pathology, AFIP Annex, 1413 Research Blvd, Rockville, MD 20850, USA
Forensic Sci Int 146:S147-9. 2004..A large-scale databasing effort targeting several populations underrepresented in current mtDNA databases is underway... - Studies of DNA dumbbells VIII. Melting analysis of DNA dumbbells with dinucleotide repeat stem sequencesKathleen E Mandell
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Room 4500, 60607, USA
Biopolymers 82:199-221. 2006....