Leslie G Ungerleider

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Experience-dependent changes in cerebellar contributions to motor sequence learning
    Julien Doyon
    Department of Psychology, University of Montreal, Montreal, QC, Canada H3C 3J7
    Proc Natl Acad Sci U S A 99:1017-22. 2002
  2. pmc Uncovering the visual "alphabet": advances in our understanding of object perception
    Leslie G Ungerleider
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Vision Res 51:782-99. 2011
  3. ncbi request reprint Cortical connections of area V4 in the macaque
    Leslie G Ungerleider
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1366, USA
    Cereb Cortex 18:477-99. 2008
  4. pmc The prefrontal cortex and the executive control of attention
    Andrew F Rossi
    Division of Neuroscience and Basic Behavioral Science, NIMH, NIH, Bethesda, MD 20892, USA
    Exp Brain Res 192:489-97. 2009
  5. pmc Relationship between functional magnetic resonance imaging-identified regions and neuronal category selectivity
    Andrew H Bell
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:12229-40. 2011
  6. ncbi request reprint Impaired filtering of distracter stimuli by TE neurons following V4 and TEO lesions in macaques
    Elizabeth A Buffalo
    Laboratory of Neuropsychology, NIMH, 49 Convent Drive, Bethesda, MD 20892, USA
    Cereb Cortex 15:141-51. 2005
  7. ncbi request reprint Visual responses to targets and distracters by inferior temporal neurons after lesions of extrastriate areas V4 and TEO
    Giuseppe Bertini
    Laboratory of Brain and Cognition, NIMH, 10 Center Drive, Bethesda, MD 20892, USA
    Neuroreport 15:1611-5. 2004
  8. pmc Dynamic and static facial expressions decoded from motion-sensitive areas in the macaque monkey
    Nicholas Furl
    Laboratories of Neuropsychology and Brain and Cognition, NIMH NIH, Bethesda, Maryland 20892, USA
    J Neurosci 32:15952-62. 2012
  9. pmc Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex
    Fadila Hadj-Bouziane
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:E3640-8. 2012
  10. ncbi request reprint Top down attentional deficits in macaques with lesions of lateral prefrontal cortex
    Andrew F Rossi
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:11306-14. 2007

Detail Information

Publications41

  1. pmc Experience-dependent changes in cerebellar contributions to motor sequence learning
    Julien Doyon
    Department of Psychology, University of Montreal, Montreal, QC, Canada H3C 3J7
    Proc Natl Acad Sci U S A 99:1017-22. 2002
    ....
  2. pmc Uncovering the visual "alphabet": advances in our understanding of object perception
    Leslie G Ungerleider
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Vision Res 51:782-99. 2011
    ..This review highlights how some of these recent technological advances have contributed to the study of visual processing and where we now stand with respect to our understanding of neural mechanisms underlying object recognition...
  3. ncbi request reprint Cortical connections of area V4 in the macaque
    Leslie G Ungerleider
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1366, USA
    Cereb Cortex 18:477-99. 2008
    ..By contrast, the predominance of central field projections from V4 to inferior temporal areas is consistent with the need for detailed form analysis for object vision...
  4. pmc The prefrontal cortex and the executive control of attention
    Andrew F Rossi
    Division of Neuroscience and Basic Behavioral Science, NIMH, NIH, Bethesda, MD 20892, USA
    Exp Brain Res 192:489-97. 2009
    ..The PFC in particular plays a critical role in the ability to switch attentional control on the basis of changing task demands...
  5. pmc Relationship between functional magnetic resonance imaging-identified regions and neuronal category selectivity
    Andrew H Bell
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:12229-40. 2011
    ....
  6. ncbi request reprint Impaired filtering of distracter stimuli by TE neurons following V4 and TEO lesions in macaques
    Elizabeth A Buffalo
    Laboratory of Neuropsychology, NIMH, 49 Convent Drive, Bethesda, MD 20892, USA
    Cereb Cortex 15:141-51. 2005
    ....
  7. ncbi request reprint Visual responses to targets and distracters by inferior temporal neurons after lesions of extrastriate areas V4 and TEO
    Giuseppe Bertini
    Laboratory of Brain and Cognition, NIMH, 10 Center Drive, Bethesda, MD 20892, USA
    Neuroreport 15:1611-5. 2004
    ..Distracters increased or decreased the response to targets more in the lesion-affected than in the normal quadrant, supporting the idea that V4 and/or TEO are sites where top-down attentional inputs filter out distracting stimuli...
  8. pmc Dynamic and static facial expressions decoded from motion-sensitive areas in the macaque monkey
    Nicholas Furl
    Laboratories of Neuropsychology and Brain and Cognition, NIMH NIH, Bethesda, Maryland 20892, USA
    J Neurosci 32:15952-62. 2012
    ..These regions may play a fundamental role in enhancing recognition of facial expression despite the complex stimulus changes associated with motion...
  9. pmc Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex
    Fadila Hadj-Bouziane
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:E3640-8. 2012
    ..Moreover, these modulatory effects are consistent with an anterior-to-posterior gradient of projections, as suggested by classical tracer studies...
  10. ncbi request reprint Top down attentional deficits in macaques with lesions of lateral prefrontal cortex
    Andrew F Rossi
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:11306-14. 2007
    ..The PFC thus appears to play a critical role in the ability to flexibly reallocate attention on the basis of changing task demands...
  11. pmc Object representations in the temporal cortex of monkeys and humans as revealed by functional magnetic resonance imaging
    Andrew H Bell
    Laboratory of Brain and Cognition, National Institute of Mental Health, 49 Convent Dr, Bethesda, MD 20892, USA
    J Neurophysiol 101:688-700. 2009
    ..In addition, they further support the idea that representations of complex stimuli in IT cortex are organized into multiple hierarchical tiers, encompassing both semantic and physical properties...
  12. pmc Posterior parietal cortex and the filtering of distractors
    Stacia R Friedman-Hill
    Laboratories of Brain and Cognition and Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 100:4263-8. 2003
    ....
  13. pmc Perception of emotional expressions is independent of face selectivity in monkey inferior temporal cortex
    Fadila Hadj-Bouziane
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 105:5591-6. 2008
    ..Thus, the neural mechanisms underlying face perception and valence perception appear to be distinct...
  14. pmc What does distractibility in ADHD reveal about mechanisms for top-down attentional control?
    Stacia R Friedman-Hill
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Cognition 115:93-103. 2010
    ....
  15. ncbi request reprint Impairments in spatial generalization of visual skills after V4 and TEO lesions in macaques (Macaca mulatta)
    Peter De Weerd
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland, USA
    Behav Neurosci 117:1441-7. 2003
    ....
  16. pmc Repetition suppression of faces is modulated by emotion
    Alumit Ishai
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:9827-32. 2004
    ..Our findings demonstrate a three-way interaction between emotional valence, repetition, and task relevance and suggest that repetition suppression is influenced by high-level cognitive processes in the human brain...
  17. ncbi request reprint Generalized deficits in visual selective attention after V4 and TEO lesions in macaques
    Peter De Weerd
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Eur J Neurosci 18:1671-91. 2003
    ..The results suggest a broad role of V4 and TEO in visual selective attention...
  18. ncbi request reprint Neuroimaging studies of attention and the processing of emotion-laden stimuli
    Luiz Pessoa
    Laboratory of Brain and Cognition, Department of Health and Human Services, National Institute of Mental Health, National Institutes of Health, 49 Convent Drive, Building 49, Room 1B80, Bethesda, MD 20892 4415, USA
    Prog Brain Res 144:171-82. 2004
    ....
  19. ncbi request reprint Neuroimaging studies of attention: from modulation of sensory processing to top-down control
    Luiz Pessoa
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 4415, USA
    J Neurosci 23:3990-8. 2003
  20. pmc Intrinsic structure of visual exemplar and category representations in macaque brain
    Ning Liu
    Section on Neurocircuitry, Laboratory of Brain and Cognition, NIMH NIH, Bethesda, MD 20892, USA
    J Neurosci 33:11346-60. 2013
    ....
  21. doi request reprint Human brain activity predicts individual differences in prior knowledge use during decisions
    Kathleen A Hansen
    National Institutes of Health, Bethesda, MD, USA
    J Cogn Neurosci 24:1462-75. 2012
    ..g., Category B targets if the 80/20 cue meant 20% probability B). The increased activity in these regions likely indicates a no-go response when sufficient perceptual evidence favored the alternative contraindicated by the 80/20 cue...
  22. pmc Individual differences in valence modulation of face-selective M170 response
    Shruti Japee
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD 20892 1366, USA
    Emotion 9:59-69. 2009
    ..These results suggest that individual differences between subjects, such as trait anxiety levels and sensitivity to fearful stimuli, may be an important factor to consider when studying emotion processing...
  23. ncbi request reprint Activations in visual and attention-related areas predict and correlate with the degree of perceptual learning
    Ikuko Mukai
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:11401-11. 2007
    ....
  24. pmc The ventral visual pathway: an expanded neural framework for the processing of object quality
    Dwight J Kravitz
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Trends Cogn Sci 17:26-49. 2013
    ....
  25. ncbi request reprint Task-independent functional brain activity correlation with skin conductance changes: an fMRI study
    James C Patterson
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Neuroimage 17:1797-806. 2002
    ..From these data, SCR appears to be a marker of a network that is active during, but independent of, the task being studied...
  26. ncbi request reprint Visual imagery of famous faces: effects of memory and attention revealed by fMRI
    Alumit Ishai
    Laboratory of Brain and Cognition, NIMH, National Institutes of Health, Bethesda, Maryland 20892 1366, USA
    Neuroimage 17:1729-41. 2002
    ..g., eyes, lips, or nose) resulted in increased activation in the right IPS and right IFG. Our results suggest differential effects of memory and attention during the generation and maintenance of mental images of faces...
  27. pmc Effects of Prior Knowledge on Decisions Made Under Perceptual vs. Categorical Uncertainty
    Kathleen A Hansen
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health Bethesda, MD, USA
    Front Neurosci 6:163. 2012
    ..When sensory evidence is difficult to perceive, prior knowledge increases visual cortical activity. When the sensory evidence is easy to perceive but difficult to interpret, prior knowledge decreases visual cortical activity...
  28. pmc Complementary roles of systems representing sensory evidence and systems detecting task difficulty during perceptual decision making
    Douglas A Ruff
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health Bethesda, MD, USA
    Front Neurosci 4:190. 2010
    ..We propose that a simple mechanism that scales a region's activity based on task demands can explain our results...
  29. pmc Development of a MR-visible compound for tracing neuroanatomical connections in vivo
    Carolyn W H Wu
    Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20814, USA
    Neuron 70:229-43. 2011
    ..These MR results were verified by classic immunohistochemical staining for CTB, in the same animals. The GdDOTA-CTB neuronal transport was target specific, monosynaptic, stable for several weeks, and reproducible...
  30. doi request reprint Fearful face detection sensitivity in healthy adults correlates with anxiety-related traits
    Tracy J Doty
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA
    Emotion 13:183-8. 2013
    ..These results underscore the important contribution of anxiety-related personality traits to threat processing in healthy adults...
  31. ncbi request reprint Attentional control of the processing of neural and emotional stimuli
    Luiz Pessoa
    Laboratory of Brain and Cognition, National Institute of Mental Health, 49 Convent Drive, Building 49, Room 1B80, Bethesda, MD 20892 4415, USA
    Brain Res Cogn Brain Res 15:31-45. 2002
    ..Thus, similar to the processing of other stimulus categories, the processing of facial expression is under top-down control...
  32. ncbi request reprint Imaging brain plasticity during motor skill learning
    Leslie G Ungerleider
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neurobiol Learn Mem 78:553-64. 2002
    ..We also briefly review neurophysiological and psychophysical evidence for the consolidation of motor skills, and we propose a working hypothesis of its underlying neural substrate in motor sequence learning...
  33. pmc Tactile form and location processing in the human brain
    Robert W Van Boven
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 102:12601-5. 2005
    ..Hence, hemispheric dominance appears to be an organizing principle for cortical processing of tactile form and location...
  34. ncbi request reprint Distinct contribution of the cortico-striatal and cortico-cerebellar systems to motor skill learning
    Julien Doyon
    Department of Psychology, University of Montreal, PO Box 6128, Downtown Station, Montreal, Que, Canada H3C3J7
    Neuropsychologia 41:252-62. 2003
    ..e. automatization) when subjects achieve asymptotic performance, as well as during reactivation of the new skilled behavior in the retention phase...
  35. ncbi request reprint Neural correlates of change detection and change blindness in a working memory task
    Luiz Pessoa
    Department of Psychology, Brown University, Providence, RI 02912, USA
    Cereb Cortex 14:511-20. 2004
    ..Whereas reporting that a change occurred, be it correctly or incorrectly, was associated with strong activation in fronto-parietal sites, change blindness appears to involve very limited territories...
  36. ncbi request reprint Target visibility and visual awareness modulate amygdala responses to fearful faces
    Luiz Pessoa
    Department of Psychology, Brown University, 89 Waterman Street, Providence, RI 02912, USA
    Cereb Cortex 16:366-75. 2006
    ..Taken together, our results further challenge the view that amygdala responses occur automatically...
  37. ncbi request reprint Bihemispheric leftward bias in a visuospatial attention-related network
    Tali Siman-Tov
    Functional Brain Imaging Unit, Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel
    J Neurosci 27:11271-8. 2007
    ..Additionally, the proposed model for asymmetry of visuospatial attention might provide important insights into the mechanisms underlying functional brain lateralization in general...
  38. ncbi request reprint Temporal dynamics of face repetition suppression
    Alumit Ishai
    Institute of Neuroradiology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Brain Res Bull 70:289-95. 2006
    ..Our data indicate that valence enhancement and context effects can be detected in extrastriate visual cortex within 250 ms and that these processes likely reflect feedback from other regions...
  39. pmc fMRI mapping of a morphed continuum of 3D shapes within inferior temporal cortex
    Roger B H Tootell
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 105:3605-9. 2008
    ..Neither result occurred; instead, we found approximately linearly graded changes in the response amplitudes to graded-shape changes, without changes in topography-similar to visual responses in different lower-tier cortical areas...
  40. ncbi request reprint Visual awareness and the detection of fearful faces
    Luiz Pessoa
    Department of Psychology, Brown University, Providence, RI 02912, USA
    Emotion 5:243-7. 2005
    ..Their findings suggest that considerable information is available even in briefly presented stimuli (possibly as short as 17 ms) to support masked fear detection...
  41. doi request reprint The neural systems that mediate human perceptual decision making
    Hauke R Heekeren
    Neurocognition of Decision Making Group, Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany
    Nat Rev Neurosci 9:467-79. 2008
    ..This leads to a new view about the neural basis of human perceptual decision-making processes...