J C Umhau
Affiliation: National Institutes of Health
- Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophyJohn C Umhau
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 8:e75333. 2013..In animal models, excessive alcohol consumption is reported to reduce brain DHA concentration, suggesting disturbed brain DHA metabolism. We hypothesized that brain DHA metabolism also is abnormal in chronic alcoholics...
- The relationship between folate and docosahexaenoic acid in menJ C Umhau
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism NIAAA, National Institutes of Health, MD 20892 1108, USA
Eur J Clin Nutr 60:352-7. 2006..The objective of this study is to determine if the blood concentrations of folate and DHA are correlated in humans...
- Hypothalamic function in response to 2-deoxy-D-glucose in long-term abstinent alcoholicsJ C Umhau
National Institute on Alcohol Abuse and Alcoholism Bethesda, Maryland 20892 1610, USA
Alcohol Clin Exp Res 25:781-6. 2001..Although many studies have examined this phenomenon in drinking and recently sober alcoholics, few studies have examined HPA axis function in long-term sober alcoholics...
- Blood glucose is correlated with cerebrospinal fluid neurotransmitter metabolitesJohn C Umhau
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 1610, USA
Neuroendocrinology 78:339-43. 2003..These correlations may represent a homeostatic relation between brain neurotransmitter activity and blood glucose...
- Atypical autonomic regulation in perpetrators of violent domestic abuseJohn C Umhau
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892, USA
Psychophysiology 39:117-23. 2002..These differences in the covariation between heart rate and RSA may represent differences in the neural regulation of heart rate and may be related to difficulties in controlling autonomic state...
- Serotonin, testosterone and alcohol in the etiology of domestic violenceD T George
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Psychiatry Res 104:27-37. 2001..These results suggest that DV-NALC and DV-ALC groups could have different biological mechanisms mediating domestic violence...
- Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomographyJ Hirvonen
Molecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892 1108, USA
Mol Psychiatry 18:916-21. 2013..The correlation of reduced binding with years of alcohol abuse suggests an involvement of CB1 receptors in alcohol dependence in humans. ..
- Long-term abstinent alcoholics have a blunted blood glucose response to 2-Deoxy-d-glucoseJohn C Umhau
National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892 1610, USA
Alcohol Alcohol 37:586-90. 2002....
- A select group of perpetrators of domestic violence: evidence of decreased metabolism in the right hypothalamus and reduced relationships between cortical/subcortical brain structures in position emission tomographyDavid T George
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, 10 Center Drive, MSC 1610, Building 10, Room 6S 240, Bethesda, MD 20892 1610, USA
Psychiatry Res 130:11-25. 2004..A possible psychological covariate of these changes in regional activity might be fear-induced aggression, but this hypothesis should be examined in larger study groups that undergo provocation during imaging...
- A model linking biology, behavior and psychiatric diagnoses in perpetrators of domestic violenceDavid T George
Laboratory of Clinical and Translational Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive MSC 1540, Bldg 10 Hatfield CRC Room 2 2352, Bethesda, MD 20892 1540, USA
Med Hypotheses 67:345-53. 2006..Linking conditioned fear and fear avoidance to the behaviors and psychiatric diagnoses will serve to change the way the medical community perceives and treats perpetrators of domestic violence...
- Omega-3 status and cerebrospinal fluid corticotrophin releasing hormone in perpetrators of domestic violenceJoseph R Hibbeln
Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852, USA
Biol Psychiatry 56:895-7. 2004..Prostaglandins E2 and F2alpha, which increase corticotrophin-releasing hormone RNA expression in this pathway, are reduced by dietary intakes of omega-3 fats...
- Folate and ageingJohn C Umhau
Lancet 369:1602. 2007