Affiliation: National Institutes of Health
- Rachmany L, Tweedie D, Rubovitch V, Li Y, Holloway H, Kim D, et al. Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration. Sci Rep. 2017;7:3735 pubmed publisher..These data imply that treatment with Ex-4 may represent a viable option for the management of secondary events triggered by blast-induced, mild traumatic brain injury that is commonly observed in militarized zones. ..
- Tweedie D, Rachmany L, Kim D, Rubovitch V, Lehrmann E, Zhang Y, et al. Mild traumatic brain injury-induced hippocampal gene expressions: The identification of target cellular processes for drug development. J Neurosci Methods. 2016;272:4-18 pubmed publisher..These processes may be further dissected to identify key factors that can be evaluated at the protein level to highlight possible treatments for TBI in human disease and potential biomarkers of neurodegenerative processes. ..