Jennifer L Troyer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Genome-wide association study implicates PARD3B-based AIDS restriction
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, Frederick, MD 21702, USA
    J Infect Dis 203:1491-502. 2011
  2. pmc FIV diversity: FIV Ple subtype composition may influence disease outcome in African lions
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, MD, USA
    Vet Immunol Immunopathol 143:338-46. 2011
  3. pmc Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA
    Am J Ophthalmol 151:999-1006.e4. 2011
  4. pmc Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
    J Acquir Immune Defic Syndr 54:343-51. 2010
  5. pmc Pathological manifestations of feline immunodeficiency virus (FIV) infection in wild African lions
    Melody E Roelke
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    Virology 390:1-12. 2009
  6. pmc Examination of disease-based selection, demographic history and population structure in European Y-chromosome haplogroup I
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Hum Genet 55:613-20. 2010
  7. pmc The evolutionary dynamics of the lion Panthera leo revealed by host and viral population genomics
    Agostinho Antunes
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America
    PLoS Genet 4:e1000251. 2008
  8. pmc Evolution of feline immunodeficiency virus in Felidae: implications for human health and wildlife ecology
    Jill Pecon-Slattery
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Frederick, MD 21702, United States
    Vet Immunol Immunopathol 123:32-44. 2008
  9. pmc FIV cross-species transmission: an evolutionary prospective
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, United States
    Vet Immunol Immunopathol 123:159-66. 2008
  10. pmc Feline immunodeficiency virus (FIV) in wild Pallas' cats
    Meredith A Brown
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Frederick, MD 21702, USA
    Vet Immunol Immunopathol 134:90-5. 2010

Detail Information

Publications22

  1. pmc Genome-wide association study implicates PARD3B-based AIDS restriction
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, Frederick, MD 21702, USA
    J Infect Dis 203:1491-502. 2011
    ..Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression...
  2. pmc FIV diversity: FIV Ple subtype composition may influence disease outcome in African lions
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, MD, USA
    Vet Immunol Immunopathol 143:338-46. 2011
    ....
  3. pmc Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA
    Am J Ophthalmol 151:999-1006.e4. 2011
    ....
  4. pmc Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
    J Acquir Immune Defic Syndr 54:343-51. 2010
    ..Clearly, further studies are warrented...
  5. pmc Pathological manifestations of feline immunodeficiency virus (FIV) infection in wild African lions
    Melody E Roelke
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
    Virology 390:1-12. 2009
    ....
  6. pmc Examination of disease-based selection, demographic history and population structure in European Y-chromosome haplogroup I
    Efe Sezgin
    Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, MD 21702 1201, USA
    J Hum Genet 55:613-20. 2010
    ..Clearly, further studies on Y-chromosome candidate loci sequencing to discover functional variants and discern the roles of evolutionary factors are warranted...
  7. pmc The evolutionary dynamics of the lion Panthera leo revealed by host and viral population genomics
    Agostinho Antunes
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America
    PLoS Genet 4:e1000251. 2008
    ..In particular, lion and FIV(Ple) variation affirms that the large, well-studied lion population occupying the greater Serengeti Ecosystem is derived from three distinct populations that admixed recently...
  8. pmc Evolution of feline immunodeficiency virus in Felidae: implications for human health and wildlife ecology
    Jill Pecon-Slattery
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Frederick, MD 21702, United States
    Vet Immunol Immunopathol 123:32-44. 2008
    ....
  9. pmc FIV cross-species transmission: an evolutionary prospective
    Jennifer L Troyer
    Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, MD 21702, United States
    Vet Immunol Immunopathol 123:159-66. 2008
    ..These studies illustrate the utility of FIV as a model to discover the variables necessary for establishment and control of lentiviral infections in new species...
  10. pmc Feline immunodeficiency virus (FIV) in wild Pallas' cats
    Meredith A Brown
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Frederick, MD 21702, USA
    Vet Immunol Immunopathol 134:90-5. 2010
    ..Histopathological examination of lymph node and spleen from infected and uninfected Pallas' cats suggests that FIV(Oma) causes immune depletion in its' native host...
  11. pmc Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression
    Sher L Hendrickson
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA
    PLoS ONE 5:e12862. 2010
    ..Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroups with presumed functional differences have been associated with differential AIDS progression...
  12. pmc Genetics and pathogenesis of feline infectious peritonitis virus
    Meredith A Brown
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702, USA
    Emerg Infect Dis 15:1445-52. 2009
    ..In addition, 5 membrane protein amino acid residues with functional potential differentiated healthy cats from cats with FIP. These findings may have potential as diagnostic markers for virulent FIP-associated FCoV...
  13. pmc Emerging viruses in the Felidae: shifting paradigms
    STEPHEN J O'BRIEN
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Frederick, MD 21702, USA
    Viruses 4:236-57. 2012
    ..The most recent interpretations indicate important new evolutionary conclusions implicating these deadly infectious agents in domestic and non-domestic felids...
  14. pmc Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection
    Leslie W Chinn
    National Cancer Institute, Rockville, MD, USA
    J Infect Dis 202:1836-45. 2010
    ..Genes conferring a significant effect were termed HIV-dependency factors (HDFs)...
  15. pmc Effect of host genetics on the development of cytomegalovirus retinitis in patients with AIDS
    Efe Sezgin
    Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, Maryland 21702 1201, USA
    J Infect Dis 202:606-13. 2010
    ..The ubiquitous CMV pathogen contains a human interleukin-10 (IL-10) homolog in its genome and utilizes it to evade host immune reactions through an IL-10 receptor mediated immune-suppression pathway...
  16. pmc Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia
    Ping An
    Basic Research Laboratory, SAIC Frederick, National Cancer Institute Frederick, Frederick, Maryland, USA
    PLoS Genet 7:e1002328. 2011
    ..28-6.31) among four major AIDS-defining conditions. Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor may affect PCP through immune regulation and inducing inflammation...
  17. pmc Accounting for multiple comparisons in a genome-wide association study (GWAS)
    Randall C Johnson
    Basic Research Program, SAIC Frederick, Inc NCI Frederick, Frederick, MD, USA
    BMC Genomics 11:724. 2010
    ..We consider seven implementations of these commonly used methods using data from 1514 European American participants genotyped for 700,078 SNPs in a GWAS for AIDS...
  18. pmc Seroprevalence and genomic divergence of circulating strains of feline immunodeficiency virus among Felidae and Hyaenidae species
    Jennifer L Troyer
    Laboratory of Genomic Diversity, National Cancer Institute Frederick, Maryland 21702 1201, USA
    J Virol 79:8282-94. 2005
    ....
  19. pmc Patterns of feline immunodeficiency virus multiple infection and genome divergence in a free-ranging population of African lions
    Jennifer L Troyer
    Laboratory of Genomic Diversity, National Cancer Institute Frederick IRSP Program, SAIC Frederick, Frederick, Maryland 21702, USA
    J Virol 78:3777-91. 2004
    ..This comprehensive study of FIV-Ple in a free-ranging population of lions reveals a dynamic transmission of virus in a social species that has historically adapted to render the virus benign...
  20. pmc Genetic characterization of feline leukemia virus from Florida panthers
    Meredith A Brown
    National Cancer Institute, Frederick, Maryland, USA
    Emerg Infect Dis 14:252-9. 2008
    ..These unique features may also account for the severity of the outbreak after cross-species transmission to the panther...
  21. pmc The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove
    Minzhong Tang
    College of Life Science and Bio engineering, Beijing University of Technology, Beijing, China
    PLoS Genet 8:e1003103. 2012
    ....
  22. pmc Association of Y chromosome haplogroup I with HIV progression, and HAART outcome
    Efe Sezgin
    NCI Frederick, MD 21702, USA
    Hum Genet 125:281-94. 2009
    ..Our results suggest that one or more loci on the Y chromosome found on haplogroup Y-I have an effect on AIDS progression and treatment responses in European Americans...