Research Topics
| Edward L TrimbleSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Intraperitoneal chemotherapy and the NCI clinical announcementEdward L Trimble
Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 02138, USA
Gynecol Oncol 103:S18-9. 2006
Untreated cervical cancer in the United StatesEdward L Trimble
Surgery Section, National Cancer Institute, 6130 Executive Boulevard, Suite 741, MSC 7436, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:271-7. 2005..To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States...
Pre-operative imaging, surgery and adjuvant therapy for women diagnosed with cancer of the corpus uteri in community practice in the United StatesEdward L Trimble
National Cancer Institute, Surgery Section, 6130 Executive Boulevard, Ste 741, M, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:741-8. 2005..Non-Hispanic black women are less often diagnosed with endometrial cancer than are non-Hispanic white women, but are more likely to die of their disease. Reasons for this disparity in outcome are not well understood...
Cervical cancer state-of-the-clinical-science meeting on pretreatment evaluation and prognostic factors, September 27-28, 2007: proceedings and recommendationsEdward L Trimble
National Cancer Institute, Bethesda, MD 20892 7436, USA
Gynecol Oncol 114:145-50. 2009..We choose to review current knowledge focused on pretreatment evaluation and prognostic markers in cervical cancer and make recommendations for future research...
National Cancer Institute-United States strategy regarding intraperitoneal chemotherapy for ovarian cancerE L Trimble
Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892 7436, USA
Int J Gynecol Cancer 18:26-8. 2008..The further development of IP chemotherapy in ovarian cancer requires additional clinical and translational research...
Improving cancer outcomes through international collaboration in academic cancer treatment trialsEdward L Trimble
National Cancer Institute, Bethesda, MD 20892 7436, USA
J Clin Oncol 27:5109-14. 2009..We sought to identify those efforts already underway which facilitate such collaboration, as well as barriers to greater collaboration...
Grants, clinical trials, and building research teamsEdward L Trimble
Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD 20892, USA
Gynecol Oncol 99:S6. 2005
Global strategies for cervical cancer control in the 21st centuryTed Trimble
National Cancer Institute, 6130 Executive Blvd, Suite 741, MSC 7436, Bethesda, MD 20892-7436, USA
Gynecol Oncol 99:S245. 2005
Summary and discussion of session recommendationsJane Fountain
National Cancer Institute, Bethesda, MD 20892, USA
Gynecol Oncol 103:S23-5. 2006
Treatment of platinum-resistant ovarian cancerE L Trimble
Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland, USA
Expert Opin Pharmacother 2:1299-306. 2001..The 5 year survival for women with stage III disease is 15-30% and 0-20% for those with stage IV disease. Medical and gynecological oncologists, therefore, must be prepared to treat many women with recurrent ovarian cancer...
Concluding remarks: optimal treatment for women with ovarian cancerEdward L Trimble
National Cancer Institute, Bethesda, MD 20892-7436, USA
Semin Oncol 33:S25-6. 2006
Current academic clinical trials in ovarian cancer: Gynecologic Cancer Intergroup and US National Cancer Institute Clinical Trials Planning Meeting, May 2009Edward L Trimble
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7436, USA
Int J Gynecol Cancer 20:1290-8. 2010..To review the current status of large phase academic clinical trials for women with ovarian cancer, address cross-cutting issues, and identify promising areas for future collaboration...
Patterns of care for women with cervical cancer in the United StatesEdward L Trimble
National Cancer Institute, Surgery Section, Bethesda, Maryland 20892 7436, USA
Cancer 113:743-9. 2008..This analysis was initiated to determine any systemic changes in management of cervical cancers...
Intraperitoneal chemotherapy for women with epithelial ovarian cancerEdward L Trimble
Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Boulevard, Suite 7025, MSC 7436, Bethesda, Maryland 20892 7436, USA
Oncologist 13:403-9. 2008..p. chemotherapy, the data supporting its use, the selection of appropriate patients for i.p. chemotherapy, how best to avoid and manage the toxicities observed with i.p. chemotherapy, and directions for future research...
Clinical trials referral resource. Clinical trials in ovarian cancer, Part 2Edward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 16:1660-2, 1665-7. 2002
Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United StatesLinda C Harlan
National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Clin Oncol 21:3488-94. 2003..We examined patterns of care in a population-based sample of 601 ovarian cancer patients diagnosed in 1991, and a sample of 566 women was selected in 1996 to examine trends in care...
Clinical Trials Referral Resource. Clinical trials in cervical cancerEdward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 17:84-9. 2003
Treatment and survival for women with Fallopian tube carcinoma: a population-based studyCarol Kosary
National Cancer Institute, Bethesda, Maryland 20892, USA
Gynecol Oncol 86:190-1. 2002..Further studies, both laboratory and clinical, are needed to delineate the differences between fallopian and ovarian cancers...
Clinical trials referral resource. Clinical trials in ovarian cancer; Part 1Edward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 16:1498-9, 1504, 1506-7. 2002
Clinical trials referral resource. Current clinical trials investigating cancer in the elderlyEdward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 17:1712-3, 1718-9. 2003
Long-term survival and patterns of care in women with ovarian tumors of low malignant potentialCornelia Liu Trimble
Department of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, Maryland, USA
Gynecol Oncol 86:34-7. 2002..Conservative surgery should be considered in younger women with early-stage disease. There are insufficient data to support a role for adjuvant chemotherapy for women with advanced disease...
Clinical trials referral resource. Current treatment trials for epithelial ovarian cancerEdward L Trimble
National Cancer Institute, Bethesda, USA
Oncology (Williston Park) 19:897-8, 900, 905-6 passim. 2005
NIH and NCI support for development of novel therapeutics in gynecologic cancer: a user's guideLucas Minig
National Cancer Institute, Bethesda, MD 20892, USA
Gynecol Oncol 116:177-80. 2010..Finally, the NIH and the NCI sponsor a variety of grant mechanisms, supporting institutions, consortia, and individuals, which investigators seeking to develop novel therapeutics should make themselves familiar...
Current clinical trials of HPV vaccinesEdward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 18:859-60, 862. 2004
Ovarian tumors of low malignant potentialCornelia Liu Trimble
Departments of Gynecology, Obstetrics, and Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Oncology (Williston Park) 17:1563-7; discussion 1567-70, 1575. 2003....
Clinical trials in gynecological cancerE L Trimble
National Cancer Institute Cancer Therapy Evaluation Program, Bethesda, MD, USA
Int J Gynecol Cancer 17:547-56. 2007..Other critical issues include support from government and charities and government regulations...
Increasing participation of physicians and patients from underrepresented racial and ethnic groups in National Cancer Institute-sponsored clinical trialsMichaele C Christian
Cancer Therapy Evaluation Program, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 12:277s-283s. 2003
Clinical trials referral resource. Current clinical trails in endometrial cancerEdward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 17:238-40, 244, 249. 2003
Health-related quality of life and symptom management research sponsored by the National Cancer InstituteLori M Minasian
Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7340, USA
J Clin Oncol 25:5128-32. 2007..The scope of NCI's research in symptom management and HRQOL is described with attention to its evolution over time and the next steps, through the Clinical Trials Working Group Recommendations...
Grantsmanship and career development for gynecologic cancer investigatorsEdward L Trimble
Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland, USA
Cancer 98:2075-81. 2003..Developing a successful academic career with a focus on research in gynecologic cancer requires planning and a supportive environment...
Clinical trials referral source. Current randomized phase III trials in gynecologic cancerEdward L Trimble
National Cancer Institute, Bethesda, MD, USA
Oncology (Williston Park) 18:1642, 1645-6. 2004
Building the evidence base for postoperative and postpartum adviceLucas Minig
Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Obstet Gynecol 114:892-900. 2009..The evidence base informing advice for most of these issues is minimal; we need prospective, well-designed studies to help guide us and our patients...
A pilot phase I trial of continuous hyperthermic peritoneal perfusion with high-dose carboplatin as primary treatment of patients with small-volume residual ovarian cancerM A Steller
Section of Gynecologic Oncology, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Chemother Pharmacol 43:106-14. 1999..Patients and..
Integrating cancer control into global healthHarold Varmus
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Sci Transl Med 3:101cm28. 2011..Here, we discuss ways in which the National Cancer Institute's newly formed Center for Global Health plans to stem the rising cancer burden in developing countries...
Hormones and endometrial cancer--new data from the Million Women StudyLouise A Brinton
National Cancer Institute, Bethesda, MD 20892, USA
Lancet 365:1517-8. 2005
Patterns of care for women with ovarian cancer in the United StatesK A Munoz
Division of Cancer Prevention and Control, and Cancer Therapy Evaluation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
J Clin Oncol 15:3408-15. 1997..To characterize treatments for ovarian cancer, to determine if recommended staging and treatment were provided, and to determine factors that influence receipt of recommended staging and treatment...
How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trialsWarren B Sateren
Walter Reed Army Institute of Research, Rockville, MD, USA
J Clin Oncol 20:2109-17. 2002..CONCLUSION: We must work to increase the number of adults who enroll onto trials, especially among the elderly. Ongoing partnership with professional societies may be an effective approach to strengthen accrual to clinical trials...
Clinical trials referral resource. Current clinical trials of supportive care/palliative careMason Schoenfeldt
EMMES Corporation, Rockville, MD, USA
Oncology (Williston Park) 17:1578, 1583-5, 1589-90. 2003
Cancer of the uterine corpus among Hispanic women living in the United States: patterns of staging, diagnosis, and primary treatmentTeresa P Diaz-Montes
The Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps 281, Baltimore, MD 21287, USA
Gynecol Oncol 96:753-9. 2005..To evaluate the demographic characteristics, clinico-pathological features, and patterns of care of uterine cancer among Hispanic women living in the United States...
Effect of surgeon specialty on processes of care and outcomes for ovarian cancer patientsCraig C Earle
Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
J Natl Cancer Inst 98:172-80. 2006..e., better outcomes). We examined associations between physician specialty and outcomes in a population-based cohort of elderly ovarian cancer surgery patients...
Cancer treatment and the older patientEdward L Trimble
Clin Cancer Res 12:1956-7. 2006
Intraperitoneal chemotherapy for women with advanced epithelial ovarian carcinomaEdward L Trimble
Gynecol Oncol 100:3-4. 2006
Patterns of care for cervical cancer patients treated in the U.S. military health care systemJohn H Farley
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, HI 96859 5000, USA
J Reprod Med 52:1040-5. 2007..S. Department of Defense (DOD) Military Health Care System received treatment within standard guidelines and whether survival was influenced by implementation of these guidelines...
Patient-reported outcomes assessment in cancer trials: taking stock, moving forwardJoseph Lipscomb
Emory University, Atlanta, GA 30322, USA
J Clin Oncol 25:5133-40. 2007....
Associations between hospital and surgeon procedure volumes and patient outcomes after ovarian cancer resectionDeborah Schrag
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Natl Cancer Inst 98:163-71. 2006..e., hospital or surgeon) procedure volumes and patient outcomes have been demonstrated for many types of cancer operation. We performed a population-based cohort study to examine these associations for ovarian cancer resections...
Practice patterns of radiotherapy in cervical cancer among member groups of the Gynecologic Cancer Intergroup (GCIG)David K Gaffney
Radiation Therapy Oncology Group, Salt Lake City, UT 84112, USA
Int J Radiat Oncol Biol Phys 68:485-90. 2007..The aim of this study was to describe radiotherapeutic practice of the treatment of cervical cancer in member groups of the Gynecologic Cancer Intergroup (GCIG)...
Ovarian cancer surgery in Maryland: volume-based access to careRobert E Bristow
Department of Biostatistics, Johns Hopkins Oncology Center, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Gynecol Oncol 93:353-60. 2004..To characterize the patterns of primary surgical care for ovarian cancer in a statewide population according to annual surgeon and hospital case volume...
Abdominal carcinomatosis in women with a history of breast cancerRuchi Garg
Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287-1281, USA
Gynecol Oncol 99:65-70. 2005..Optimal cytoreductive surgery was associated with a significant survival advantage for patients with primary ovarian/peritoneal cancer...
Participation of patients 65 years of age or older in cancer clinical trialsJoy H Lewis
RAND Health, Santa Monica, CA 90407 2138, USA
J Clin Oncol 21:1383-9. 2003..Our objective was to evaluate the participation of the elderly in clinical trials sponsored by the National Cancer Institute (NCI) and assess the impact of protocol exclusion criteria on elderly participation...
Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysisRobert E Bristow
Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD 21287 1248, USA
J Clin Oncol 20:1248-59. 2002..To evaluate the relative effect of percent maximal cytoreductive surgery and other prognostic variables on survival among cohorts of patients with advanced-stage ovarian carcinoma treated with platinum-based chemotherapy...
