G S Travlos

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Chronic progressive nephropathy in male F344 rats in 90-day toxicity studies: its occurrence and association with renal tubule tumors in subsequent 2-year bioassays
    Greg S Travlos
    National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA
    Toxicol Pathol 39:381-9. 2011
  2. ncbi request reprint Histopathology of bone marrow
    Gregory S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 34:566-98. 2006
  3. ncbi request reprint The effect of short intermittent light exposures on the melatonin circadian rhythm and NMU-induced breast cancer in female F344/N rats
    G S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 29:126-36. 2001
  4. ncbi request reprint Normal structure, function, and histology of the bone marrow
    Gregory S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 34:548-65. 2006
  5. ncbi request reprint Toxicity of 3,3',4,4'-tetrachloroazoxybenzene in rats and mice
    A P van Birgelen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Appl Pharmacol 156:206-21. 1999
  6. ncbi request reprint Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice
    R S Chhabra
    National Institute of Environmental Health Sciences, 111 Alexander Drive, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 60:28-37. 2001
  7. ncbi request reprint Toxicity of 3,3',4,4'-tetrachloroazobenzene in rats and mice
    A P van Birgelen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA
    Toxicol Appl Pharmacol 156:147-59. 1999
  8. ncbi request reprint 14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice
    K M Abdo
    National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
    Food Chem Toxicol 39:303-16. 2001
  9. ncbi request reprint Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate
    M C Rhodes
    National Institute of Environmental Health Sciences, Mail Drop EC 34, 79 TW Alexander Drive, Research Triangle Park, NC 27709, United States
    Food Chem Toxicol 43:21-9. 2005
  10. doi request reprint Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal
    Matthew D Stout
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    Toxicol Pathol 36:232-46. 2008

Collaborators

Detail Information

Publications24

  1. doi request reprint Chronic progressive nephropathy in male F344 rats in 90-day toxicity studies: its occurrence and association with renal tubule tumors in subsequent 2-year bioassays
    Greg S Travlos
    National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA
    Toxicol Pathol 39:381-9. 2011
    ....
  2. ncbi request reprint Histopathology of bone marrow
    Gregory S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 34:566-98. 2006
    ....
  3. ncbi request reprint The effect of short intermittent light exposures on the melatonin circadian rhythm and NMU-induced breast cancer in female F344/N rats
    G S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 29:126-36. 2001
    ..This finding was unexpected and suggests that melatonin can be produced by an organ or tissue other than the pineal gland...
  4. ncbi request reprint Normal structure, function, and histology of the bone marrow
    Gregory S Travlos
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 34:548-65. 2006
    ..In addition to discussing normal structure, function, and histology of bone marrow, methods for preparation and evaluation of bone marrow are presented...
  5. ncbi request reprint Toxicity of 3,3',4,4'-tetrachloroazoxybenzene in rats and mice
    A P van Birgelen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Appl Pharmacol 156:206-21. 1999
    ..No no-observed-adverse-effect level was reached in male or female rats or mice...
  6. ncbi request reprint Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice
    R S Chhabra
    National Institute of Environmental Health Sciences, 111 Alexander Drive, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 60:28-37. 2001
    ..A no-observed-adverse-effect level (NOAEL) of 30 ppm DDS in the diet (1.5 mg/kg body weight) was established for rats. DDS was not carcinogenic in these studies...
  7. ncbi request reprint Toxicity of 3,3',4,4'-tetrachloroazobenzene in rats and mice
    A P van Birgelen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA
    Toxicol Appl Pharmacol 156:147-59. 1999
    ....
  8. ncbi request reprint 14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice
    K M Abdo
    National Institute of Environmental Health Sciences, Research, Triangle Park, NC 27709, USA
    Food Chem Toxicol 39:303-16. 2001
    ..Based on mortality, body weight gain, clinical chemistry and gross and microscopic evaluation of tissues of rats and mice, the no-observed-effect level (NOEL) of methyleugenol for both species was estimated at 10 mg/kg...
  9. ncbi request reprint Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate
    M C Rhodes
    National Institute of Environmental Health Sciences, Mail Drop EC 34, 79 TW Alexander Drive, Research Triangle Park, NC 27709, United States
    Food Chem Toxicol 43:21-9. 2005
    ..No compound-related changes in hematology and clinical chemistry parameters were observed. There were no histopathological lesions attributed to CPM in rats or mice...
  10. doi request reprint Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal
    Matthew D Stout
    Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA
    Toxicol Pathol 36:232-46. 2008
    ..These findings suggest that the toxicity of hexenal was limited to the site of contact (stomach) and that the observed DNA adduct formation and cell proliferation occurred in the setting of severe tissue damage...
  11. ncbi request reprint Disseminated thrombosis and bone infarction in female rats following inhalation exposure to 2-butoxyethanol
    A Nyska
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 27:287-94. 1999
    ..In conclusion, exposure to 500 ppm BE vapors caused acute disseminated thrombosis and bone infarction in female rats. Possible pathogenic mechanisms are discussed...
  12. pmc Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure
    Matthew D Stout
    National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 117:716-22. 2009
    ..Hexavalent chromium [Cr(VI)] is a human carcinogen after inhalation exposure. Humans also ingest Cr(VI) from contaminated drinking water and soil; however, limited data exist on the oral toxicity and carcinogenicity of Cr(VI)...
  13. pmc IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women
    Aimee A D'Aloisio
    Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, Mail Drop A3 05, Research Triangle Park, NC 27709, USA
    Cancer Epidemiol Biomarkers Prev 18:954-66. 2009
    ..Our study supports that common IGFBP-3 SNPs, especially rs2854746, influence plasma IGFBP-3 levels among African Americans and Caucasians but provides less evidence that IGF-I SNPs affect plasma IGF-I levels...
  14. pmc A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein
    Scott S Auerbach
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Toxicology 253:79-88. 2008
    ..Increased systemic exposure to acrolein is likely responsible for the differences in hepatic toxicological profile observed with these chemicals...
  15. doi request reprint Toxicity and carcinogenicity studies of methylene blue trihydrate in F344N rats and B6C3F1 mice
    Scott S Auerbach
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Food Chem Toxicol 48:169-77. 2010
    ..There were no significant increases in neoplastic transformation observed in the mice; however, positive trends were noted for adenoma or carcinoma (combined) of the small intestine and malignant lymphoma...
  16. pmc Inclusion of biomarkers for detecting perturbations in the heart and lung and lipid/carbohydrate metabolism in National Toxicology Program studies
    June K Dunnick
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 100:29-35. 2007
    ..Breakout group reports and additional information on the workshop, including participants, presentations, and background materials, are posted on the NTP Web site http://ntp.niehs.nih.gov/go/20940...
  17. ncbi request reprint Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China
    Stephanie J London
    Epidemiology Branch and Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 94:749-54. 2002
    ..In a prospective study of men in Shanghai, China, we examined the association between serum levels of IGF-I and IGFBP-3 and the subsequent risk of lung cancer...
  18. ncbi request reprint Early changes in sex hormones are not evident in mice exposed to the uterine carcinogens chloroethane or bromoethane
    J R Bucher
    National Institute of Environmental Health Sciences, Mantech Inc, Research Triangle Park, North Carolina
    Toxicol Appl Pharmacol 130:169-73. 1995
    ..Thus, the findings suggest that early changes in circulating sex hormones are not important contributing factors in the uterine neoplasia caused by these chemicals...
  19. ncbi request reprint Gene expression profiling of rat livers reveals indicators of potential adverse effects
    Alexandra N Heinloth
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 80:193-202. 2004
    ..In conclusion, this study provides evidence that supports the hypothesis that gene expression profiling may be a sensitive means of identifying indicators of potential adverse effects in the absence of the occurrence of overt toxicity...
  20. ncbi request reprint Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice
    N B Ress
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 71:198-206. 2003
    ..However, the incidences were within the NTP historical control range and could not be clearly related to citral administration...
  21. ncbi request reprint Subchronic sodium chlorate exposure in drinking water results in a concentration-dependent increase in rat thyroid follicular cell hyperplasia
    M J Hooth
    Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Toxicol Pathol 29:250-9. 2001
    ..Follicular cell hyperplasia was not present in male or female B6C3F1 mice. These data can be used to estimate the human health risk that would be associated with using ClO2, rather than chlorine, to disinfect drinking water...
  22. pmc Heat map visualization of high-density clinical chemistry data
    J Todd Auman
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Physiol Genomics 31:352-6. 2007
    ..The value of this clinical chemistry data transformation and visualization will manifest itself through integration with other high-density data, such as genomics data, to study physiology at the systems level...
  23. ncbi request reprint Obesity and insulin-like growth factor-I in African Americans and Whites
    Donna Day Baird
    Cancer Epidemiol Biomarkers Prev 16:1526; author reply 1526. 2007
  24. ncbi request reprint Preconceptional fasting of fathers alters serum glucose in offspring of mice
    Lucy M Anderson
    Laboratory of Comparative Carcinogenesis, National Cancer Institute, Frederick, Maryland, USA
    Nutrition 22:327-31. 2006
    ..Maternal nutrition has long-term effects on offspring characteristics. Similar effects mediated through fathers have not been tested...